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Dorzolamide is used as a treatment for glaucoma, and is often prescribed by veterinarians for use with dogs and cats. This drug contains a carbonic anhydrase inhibitor which decreases intraocular pressure, a characteristic of many types of glaucoma.
Dorzolamide HCl inhibits carbonic anhydrase II. Inhibition of carbonic anhydrase decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. The result is a reduction in intraocular pressure (IOP).
Dorzolamide HCl Ophthalmic Solution is a carbonic anhydrase inhibitor indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.