Itrafungol is for oral use in cats only and requires a prescription from your veterinarian. Itrafungol is an antifungal oral solution used to treat dermatophytosis, also known as ringworm. Itrafungol can be given with or without food. The solution is available in a 52 ml 10mg/ml bottle and comes with an oral dosing syringe. The solution should be administered orally using the enclosed graduated dosing syringe. Do not invert the bottle when filling the syringe.
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Itrafungol for Cats - Oral Solution for Cats (52 ml) - [Ringworm Treatment]
Item# 63423
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Description
Itrafungol (Itraconazole Oral Solution) is used to treat ringworm in cats caused by a fungus infection. Cats with ringworm typically have patches of hair loss, scaling, crusting, and redness, with or without itchiness. Most skin lesions are found around the ears and face or on the legs. The disease is most commonly seen in kittens.
Itrafungol Use
Itrafungol oral solution is used for treating dermatophytosis caused by Microsporum in cats.
Key Benefits
- Easy to administer with oral dosing syringe
- Delicious with cherry flavor
- Cost-effective
How It Works
Itrafungol is a cherry caramel-flavored liquid that is easy to dose and easy to administer. It requires a short course of pulse therapy oral dosing on alternate weeks for three treatment cycles.
Ingredients
Active Ingredient: 10 mg Itraconazole
Directions
View Itrafungol package insert for more information
The solution should be administered orally using the graduated dosing syringe.
The daily dosage is 5 mg/kg body weight administered once daily on alternating weeks for 3 treatment cycles. Cats are treated during weeks 1, 3, and 5, and left untreated during weeks 2 and 4.
Dosage Table
Dosage & Administration
- The solution should be administered orally using the enclosed graduated dosing syringe. Keep the bottle upright and insert the dosing syringe through the opening of the top of the bottle (Figure 1).
- DO not invert the bottle (Figure 2).
- Fill the syringe by pulling the plunger until it reaches the graduation corresponding to the correct mL dose as indicated at the top of the syringe ring (Figure 3).
- Treat the cat by slowly and gently administering the liquid into the mouth, allowing the cat to swallow the product (Figure 4).
For cats weighing more than 13.0 lbs, the total dose will need to be calculated and given over two doses as the dosing syringe only holds 3.0 mL of solution.
After dosing, the syringe should be removed from the bottle, rinsed and dried and the bottle cap should be screwed back on tightly.
Storage Directions
Store at 68-77°F (20-25°C). Excursions permitted between 59-86°F (15-30°C). Keep away from children and pets.
Contraindications
Do not administer to cats with hypersensitivity to itraconazole.
Warnings
Itrafungol (itraconazole oral solution) has not been shown to be safe in pregnant cats (see Animal Safety section). Itrafungol should only be used in pregnant or lactating cats when the benefits outweigh the potential risks.
User Safety Warnings
Not for use in humans. Keep this and all medications out of reach of children. Wash hands and exposed skin after use. In case of accidental contact with eyes, rinse thoroughly with water. In case of pain or irritation, seek medical advice. In case of accidental ingestion, rinse mouth with water and seek medical advice.
Special precautions for person administering the veterinary product to the animal:
Microsporum canis dermatophytosis is a zoonotic disease (a disease that can be transmitted from animals to humans); therefore consult a physician if a suspected lesion occurs on a human. Wear protective gloves when handling the animal during treatment or when cleaning the syringe. Wash hands and exposed skin after handling the animal.
Itrafungol has not been shown to be sporicidal; therefore in order to reduce zoonotic potential, environmental contamination, and to decrease course of the disease, topical and environmental treatment should also be utilized.
Precautions
Itrafungol has been associated with renal changes found on histopathology that were not noted after an eight week recovery period (see Animal Safety). Use with caution in cats with renal dysfunction.
Itrafungol is metabolized by the liver (mainly CYP3A) and can cause elevated liver enzymes (see Animal Safety section). Use with caution in cats with impaired liver function. If clinical signs suggestive of liver dysfunction develop, treatment should be discontinued.
Itrafungol is a cytochrome p-450 inhibitor and may increase or prolong plasma concentrations of other drugs metabolized by this pathway, such as amitriptyline, amlodipine, benzodiazepines, buspirone, cisapride, corticosteroids, cyclosporine, ivermectin, and macrolide antibiotics.
Negative effects have been reported in literature when itraconazole was administered intravenously to dogs and healthy human volunteers. Cats suffering from heart disease should be carefully monitored during treatment.
FAQ
Tell your veterinarian if your cat is pregnant, breeding or lactating. Tell your veterinarian if your cat is hypersensitive to Itrafungol's active ingredient, itraconazole. Consult with your veterinarian if your cat has renal dysfunction, impaired liver function, or heart disease.
Itrafungol should be administered orally using the enclosed graduated dosing syringe. The daily dosage is 5 mg/kg (0.5 ml/kg) body weight administered once daily on alternating weeks for 3 treatment cycles. Cats are treated during weeks 1, 3, and 5 and left untreated during weeks 2 and 4. Each line on the dosing syringe represents 0.05 ml of oral solution. Keep the bottle upright and insert the dosing syringe through the opening on the top of the bottle. Do not invert the bottle. Fill the syringe by pulling the plunger until it reaches the graduation corresponding to the correct ml dose as indicated at the top of the syringe ring. Slowly and gently administer the liquid into the mouth, allowing your cat to swallow the product. For cats weighing over 13 lbs, the total dose will need to be calculated and given over two doses as the dosing syringe only holds 3.0 ml of solution.
Side effects of Itrafungol may include hypersalivation during or immediately following dosing, vomiting, and loose stool.
Administer the missed dose as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose. Do not give a double dose.
If an overdose is suspected, contact your veterinarian.
Avoid giving to pregnant, breeding or lactating pets. Do not give to pets that are hypersensitive to itraconazole.
Tell your veterinarian about any medications or supplements your pet is taking. Itrafungol may interact with amitriptyline, amlodipine, benzodiazepines, buspirone, cisapride, corticosteroids, cyclosporine, ivermectin, and macrolide antibiotics.
Reviews
Review Summary
4.3
4 Reviews
5
50% (2)
4
25% (1)
3
25% (1)
2
0% (0)
1
0% (0)
100% Recommend this product (4 of 4 responses)
By Elaine
Pahoa, Hawaii
Really helpful
January 26, 2021
I love Itrafungol, use it frequently on my fostered rescues in order to speed up recovery from ringworm. My local vets think it’s too strong and don’t recommend it, but I’ve had no issues in three plus years of treating many kittens. I’ve recently started combining it with lime sulphur dip, and using the dip as a preventative on all the other kittens who may be sharing air with the infected ones. So far, that has stopped any cross-infection. I also use a topical, currently ketoconazole with chlorhexadine, but am wondering what foam topical Beth is using.
Merchant Response:Hi Elaine, we will work harder to get better pricing. It is our goal to make sure that we have the best price anywhere. Give us a call directly if you find otherwise. You take care.
Pros
- Easy to dose
- Starts to work quickly, for most cats
Cons
- Expensive!
- Some vets won't prescribe
By Beth
Virginia
Excellent Product - Careful Where You Get Your Information
October 21, 2020
I have no doubt that the reviewer from Dale City Florida, adores cats and is doing a great job. That said, his information about best practices for cats with ringworm is somewhat outdated.
Examples:
1) This medicine should never be used alone - there always has to be external and internal treatment, or ringworm will return.
2) Dipping/bathing is no longer recommended. Instead, a spray is used, which is less traumatic for the cat and the liquid won’t be contaminated by multiple cats. 2) Bleach is not needed. It’s been well documented that regular laundry detergent and *sufficient* water will eliminate infected fur and spores. Only a culture will tell if a cat is completely cured, and plucking fur is no longer recommended. A more accurate and completely painless method is using a toothbrush. Wear different clothing in rooms with ringworm cats versus healthy cats. Launder clothing and their bedding daily. Mop or vacuum frequently. Please make sure you are getting up-to-date, recent information.
Examples:
1) This medicine should never be used alone - there always has to be external and internal treatment, or ringworm will return.
2) Dipping/bathing is no longer recommended. Instead, a spray is used, which is less traumatic for the cat and the liquid won’t be contaminated by multiple cats. 2) Bleach is not needed. It’s been well documented that regular laundry detergent and *sufficient* water will eliminate infected fur and spores. Only a culture will tell if a cat is completely cured, and plucking fur is no longer recommended. A more accurate and completely painless method is using a toothbrush. Wear different clothing in rooms with ringworm cats versus healthy cats. Launder clothing and their bedding daily. Mop or vacuum frequently. Please make sure you are getting up-to-date, recent information.
Pros
- Assuming you're also using a foam or other external treatment, this medicine works. Internal and external treatment should always be done in tandem. We happen to use a foam three times a week. Our cat doesn't mind the flavor - very mild, slightly cherry.
Cons
- 2.75 mls is a lot of medicine (for a 12 pound cat). And the real con? After using the syringe and cleaning it after each use, the action isn?t smooth. Being able to buy other syringes of the same type would be appreciated. Separate syringes our vet gave us do not fit into the grid.
By Mark S.
Dade City, FL
Itrafungol good or bad?
March 28, 2020
I rescue cats and I'm part of the TNVR program. I have several rooms where I rotate cats that I catch depending on how they look - sick or healthy. I have to keep them in these rooms because there is quite a wait sometimes to get with the local vet to get them fixed, and I can't be sure if I'm going to be able to catch/trap them again. People have moved and left cats, or just don't get the ones they have fixed, so there was a big problem with the rise of cats in my neighborhood for a while. At any rate, I try to work with the cats once I have them inside to actually see if they can be rehomed or will need to be released. If you forget to wash your hands, or the cat gets out of it's room, you can have problems. This would be the case, and ringworm has no mercy. Once you realize you have a problem, it's too late. Everything must be cleaned with Clorox - beds, comforters, anywhere a cat lays, and more. I have been prescribed Terbinafine, Douxo AntiSeptic Chlorhexidine + Climbazole shampoo and mousse, Itrafungol, and much more. As far as Itrafungol, it will work ok on some cats, but if you have cats with long hair, it will not work by itself. And putting the mousse on your cat (especially ones with long hair) not only gets messy, but the hair mats up and they can't wait to get a bath with the medicated shampoo. I have one cat that I've had on both the topical (Chlorhexidine + Climbazole shampoo and mousse), and oral (Itrafungol) for almost a year now. Every time it looks like it's gone away, it just comes back. This poor cat has been given so many different topical and oral solutions, nothing should survive it. But sadly, the ringworm continues. And I have to constantly clean up every space she lays in so that other cats don't get it back. I'm still fighting it, but Itrafungol does seem to work easily on some cats. It is much better to use an oral medication than having to constantly put topical medications on them and then give them a bath to wash them off. Cats don't really like baths. Except for the one who has had this almost a year, she looks forward to getting the mousse off of her - I guess she doesn't like the 80's spiked hair look.
Pros
- It is much easier to fight ring worm from the inside rather than the outside. But once it starts working on some cats, you can stop using the topicals and it will do its job.
Cons
- It just doesn't work well on all cats. Sometimes you have to use quite a bit of topical solution to get rid of ring worm. I don't think the 1 week on, 1 week off works. But I'm afraid of it building up too much and causing problems with my babies.
By MI M.
MI
Love the product/HATE the ringworm
November 29, 2017
On the day I was calling the vet to make the appointment for the kittens spay/neuters, I found the white crusty area on one of the boys' ears...then another red crusty area above the eye on one of the girls. Where the heck did they come from? They weren't there last night. Having seen enough ringworm, I was pretty sure I was looking at it again. I immediately went to the supply box and got the miconazole nitrate cream. For those who are unfamiliar with this product or why/how it is used, it is found in the feminine product aisle, normally used for vaginal yeast infections. it is much less expensive than anything by prescription. I have also used a product given for jock itch which worked pretty well. However, DO NOT use internally with the kittens, just apply to the affected areas. I do it 3 times a day. I also use the Itrafungol Oral Solution in conjunction with the cream. My vet said to use it for three weeks with no breaks. The directions on the bottle say to use for 1 week on, 1 week off, for three cycles. I gave it to them for the 3 weeks, took off a week, then 1 more week on. I was so sick that these kittens had gotten the ringworm, which delayed their going to their forever homes for ever a month, that I wanted it gone quickly. I believe that the Itrafungol Oral Solution worked wonderfully, in conjunction with the cream, in getting rid of the ringworm. All 8 kittens were clear of any symptoms, hair growing back on affected areas, within 3 weeks. I probably would not have had to treat that last week, however, I did not want to take any chances, especially with them going to their forever homes. This bout of ringworm was cleared up 3 weeks faster than my other 2 experiences with it. I do, however, believe it should be used in conjunction with the miconazole cream for the best results. Hopefully, I will never have to use the product again, but I wouldn't hesitate if needed and would gladly recommend it to others. Thank you for a wonderful product to treat ringworm.
A grateful kitten momma
A grateful kitten momma
