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Sentinel Spectrum is a brand of chewable tablets used for the prevention and control of various parasites in dogs. It provides broad-spectrum protection against fleas, heartworms, hookworms, roundworms, and whipworms.
Remember, while Sentinel Spectrum provides protection against several parasites, it does not protect against ticks. If you are in an area where ticks are prevalent, you may need to use an additional tick prevention product recommended by your veterinarian.
It's always advisable to consult your veterinarian for personalized advice regarding your dog's specific needs and to determine the most suitable parasite prevention regimen.
Sentinel Spectrum is indicated for the prevention and control of the following parasites in dogs:
The use of Sentinel Spectrum provides comprehensive protection against these parasites, ensuring the overall health and well-being of your dog. It is important to administer the product according to the recommended dosage and frequency as prescribed by your veterinarian.
Sentinel Spectrum works through the combined action of its active ingredients: Milbemycin Oxime, Lufenuron, and Praziquantel. Each ingredient targets different parasites and works in specific ways to prevent and control infestations.
By combining these active ingredients into a single product, Sentinel Spectrum provides comprehensive protection against fleas, heartworms, roundworms, hookworms, whipworms, and certain species of tapeworms. Regular administration of the chewable tablets ensures continuous protection and helps prevent reinfestation. However, it's important to note that Sentinel Spectrum does not provide protection against ticks, so additional measures may be necessary if tick prevention is required in your area.
Sentinel Spectrum Orange for Dogs 2-8 lbs: | |
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Active Ingredient (per chewable tablet) | Amount |
Milbemycin Oxime | 2.3 mg |
Lufenuron | 46 mg |
Praziquantel | 22.8 mg |
Sentinel Spectrum Green for Dogs 8.1-25 lbs: | |
Active Ingredient (per chewable tablet) | Amount |
Milbemycin Oxime | 5.75 mg |
Lufenuron | 115 mg |
Praziquantel | 57 mg |
Sentinel Spectrum Yellow for Dogs 25.1-50 lbs: | |
Active Ingredient (per chewable tablet) | Amount |
Milbemycin Oxime | 11.5 mg |
Lufenuron | 230 mg |
Praziquantel | 114 mg |
Sentinel Spectrum Blue for Dogs 50.1-100 lbs: | |
Active Ingredient (per chewable tablet) | Amount |
Milbemycin Oxime | 23 mg |
Lufenuron | 460 mg |
Praziquantel | 228 mg |
View Sentinel Spectrum Drug Facts Sheet.
Sentinel Spectrum should be administered orally, once every month, at the minimum dosage of 0.23 mg/lb (0.5 mg/kg) milbemycin oxime, 4.55 mg/lb (10 mg/kg) lufenuron, and 2.28 mg/lb (5 mg/kg) praziquantel. For heartworm prevention, give once monthly for at least 6 months after exposure to mosquitoes (see Effectiveness).
Dosage Schedule | ||||
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Body Weight | Milbemycin Oxime Per Chewable | Lufenuron Per Chewable | Praziquantel Per Chewable | Number of Chewables |
2 to 8 lbs | 2.3 mg | 46 mg | 22.8 mg | 1 (Orange) |
8.1 to 25 lbs | 5.75 mg | 115 mg | 57 mg | 1 (Green) |
25.1 to 50 lbs | 11.5 mg | 230 mg | 114 mg | 1 (Yellow) |
50.1 to 100 lbs | 23.0 mg | 460 mg | 228 mg | 1 (Blue) |
Over 100 lbs | Administer the appropriate combination of chewables |
To ensure adequate absorption, always administer Sentinel Spectrum to dogs immediately after or in conjunction with a normal meal.
Sentinel Spectrum may be offered to the dog by hand or added to a small amount of dog food. The chewables should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Chewables may be broken into pieces and fed to dogs that normally swallow treats whole. Care should be taken that the dog consumes the complete dose, and treated animals should be observed a few minutes after administration to ensure that no part of the dose is lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.
Sentinel Spectrum should be administered at monthly intervals beginning within 1 month of the dog’s first seasonal exposure to mosquitoes and continuing until at least 6 months after the dog’s last seasonal exposure (see Effectiveness). Sentinel Spectrum may be administered year-round without interruption. When switching from another heartworm preventative product to Sentinel Spectrum, the first dose of Sentinel Spectrum should be given within a month of the last dose of the former product.
Treatment with Sentinel Spectrum may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with Sentinel Spectrum should continue the entire year without interruption.
To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product, as necessary.
Dogs may be exposed to and can become infected with roundworms, whipworms, hookworms, and tapeworms throughout the year, regardless of season or climate. Clients should be advised of appropriate measures to prevent reinfection of their dog with intestinal parasites. Because the prepatent period for E. multilocularis may be as short as 26 days, dogs treated at the labeled monthly intervals may become reinfected and shed eggs between treatments.
There are no known contraindications to the use of Sentinel Spectrum.
Not for use in humans. Keep this and all drugs out of the reach of children.
Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention (see Effectiveness).
Prior to administration of Sentinel Spectrum, dogs should be tested for existing heartworm infections. At the discretion of the veterinarian, infected dogs should be treated to remove adult heartworms. Sentinel Spectrum is not effective against adult D. immitis.
Mild, transient hypersensitivity reactions, such as labored breathing, vomiting, hypersalivation, and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae.
Do not use in puppies less than six weeks of age.
Do not use in dogs or puppies less than two pounds of body weight.
The safety of Sentinel Spectrum has not been evaluated in dogs used for breeding or in lactating females. Studies have been performed with milbemycin oxime and lufenuron alone (see Animal Safety).
The following adverse reactions have been reported in dogs after administration of milbemycin oxime, lufenuron, or praziquantel: vomiting, depression/lethargy, pruritus, urticaria, diarrhea, anorexia, skin congestion, ataxia, convulsions, salivation, and weakness.
To report suspected adverse drug events, contact Virbac at 1-800-338-3659 or the FDA at 1-888-FDA-VETS.
For technical assistance call Virbac at 1-800-338-3659.
Echinococcus multilocularis and Echinococcus granulosus are tapeworms found in wild canids and domestic dogs. E. multilocularis and E. granulosus can infect humans and cause serious disease (alveolar hydatid disease and hydatid disease, respectively). Owners of dogs living in areas where E. multilocularis or E. granulosus are endemic should be instructed on how to minimize their risk of exposure to these parasites, as well as their dog’s risk of exposure. Although Sentinel Spectrum was 100% effective in laboratory studies in dogs against E. multilocularis and E. granulosus, no studies have been conducted to show that the use of this product will decrease the incidence of alveolar hydatid disease or hydatid disease in humans. Because the prepatent period for E. multilocularis may be as short as 26 days, dogs treated at the labeled monthly intervals may become reinfected and shed eggs between treatments.
In a well-controlled laboratory study, Sentinel Spectrum was 100% effective against induced heartworm infections when administered once monthly for 6 consecutive months. In well-controlled laboratory studies, neither one dose nor two consecutive doses of Sentinel Spectrum provided 100% Effectiveness against induced heartworm infections.
Elimination of the adult stage of hookworm (Ancylostoma caninum), roundworm (Toxocara canis, Toxascaris leonina), whipworm (Trichuris vulpis) and tapeworm (Echinococcus multilocularis, Echinococcus granulosus, Taenia pisiformis) infections in dogs was demonstrated in well-controlled laboratory studies.
In well-controlled studies, Sentinel Spectrum was effective in preventing flea eggs from hatching, thus providing control of the development of flea populations (Ctenocephalides felis).
In a field study of 117 dogs offered Sentinel Spectrum, 113 dogs (96.6%) accepted the product when offered from the hand as if a treat, 2 dogs (1.7%) accepted it from the bowl with food, 1 dog (0.9%) accepted it when it was placed in the dog’s mouth, and 1 dog (0.9%) refused it.
Sentinel Spectrum should be administered orally, once every month with dosing based on your dog's weight. For heartworm prevention, give once monthly for at least 6 months after exposure to mosquitoes. Sentinel Spectrum should be given once a month, every month of the year. Preferably, Sentinel Spectrum should be given on the same date each month. For dogs and puppies 2-8 lbs, give 1 chewable every month (Orange box). For dogs 8.1-25 lbs, give 1 chewable every month (Green box). For dogs 25.1-50 lbs, give 1 chewable every month (Yellow box). For dogs 50.1-100 lbs, give 1 chewable every month (Blue box). For dogs over 100 lbs, give the appropriate combination of chewables.
To ensure complete absorption, always give Sentinel Spectrum chewables to dogs either with or immediately after a normal meal. Food is essential for proper absorption of the product into the bloodstream. Most dogs like the taste of the Sentinel Spectrum chewable and will accept the chewable readily as a treat. The chewables should be administered in a manner that encourages the dog to chew, rather than to swallow the medication without chewing. The chewables may be broken into pieces and fed to dogs that normally swallow treats whole.
Sentinel Spectrum should be administered at monthly intervals beginning within 1 month of the dogs first seasonal exposure to mosquitoes and continuing until at least 6 months after the dogs last seasonal exposure. Sentinel Spectrum may be administered year-round without interruption. When switching from another heartworm preventative product to Sentinel Spectrum, the first dose of Sentinel Spectrum should be given within a month of the last dose of the former product.
Both products protect dogs against heartworms, roundworms, and hookworms, but Sentinel Spectrum Chews, with its unique combination of ingredients, protects against 3 additional common parasites that Heartgard® doesn't: fleas, whipworms, and tapeworms.
Sentinel® Spectrum® Chews (milbemycin oxime/lufenuron/praziquantel) - Dogs should be tested for heartworm prior to use. Mild hypersensitivity reactions have been noted in some dogs carrying a high number of circulating microfilariae. Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention.