NexGard Chewables for Dogs | On Sale | EntirelyPets Rx
Licensed U.S. Pet Pharmacy | Verified Pharmacy

NexGard Flea & Tick Chewables for Dogs

Item#
FREE SHIPPING Over $49! * Pet Food & Other Exclusions
1. Select weight:
2. Select dosage:
QTY:-+

Price too low to show

Add to cart to see low price
Recurring Saings in EprxAUTOSHIP & SAVE[Details]
$17.95Reg $23.99
$52.95Reg $68.99
$99.95Reg $129.99
$199.95Reg $259.99
$18.05Reg $23.99
$53.95Reg $70.99
$102.95Reg $133.99
$204.95Reg $266.99
$18.59Reg $24.99
$55.95Reg $72.99
$105.95Reg $137.99
$209.95Reg $272.99
$18.99Reg $24.99
$56.95Reg $74.99
$107.95Reg $140.99
$215.95Reg $280.99
  • Description
  • Ingredients
  • Directions
  • FAQ
  • Reviews

Description

NexGard Flea & Tick Chewables for dogs is a brand new, revolutionary flea and tick preventative from the makers of Frontline®, the #1 choice of veterinarians. It's the first flea and tick killer of its kind because it comes in a yummy, beef-flavored soft chew that protects your dog from flea and tick infestations for a full 30 days. That means you no longer have to worry about messy topicals or accidentally washing it off your dog while bathing! It can also be taken alongside your dog's heartworm medication without interruption for your convenience.

NexGard keeps your pet protected from adult fleas by killing them before they have a chance to lay eggs, which reduces the possibility of a flea infestation. It also kills the American dog tick, which decreases the risk of your pet developing a deadly tick-borne disease.

Key Benefits

  • First ever flea and tick preventative from the makers of Frontline that comes in a tasty beef-flavored chew
  • No more messy topical preventatives, and no more worrying about washing off your dog's flea protection
  • Safe, effective, FDA-approved, and lasts for 30 days
  • Can be taken alongside heartworm medication

Indications

NexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of Black-legged tick (Ixodes scapularis), American Dog tick (Dermacentor variabilis), Lone Star tick (Amblyomma americanum), and Brown dog tick (Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month.

How It Works

NexGard contains a brand new ingredient not used in any other flea and tick protection. Afoxolaner, the ingredient in NexGard, is rapidly absorbed into your pet's bloodstream where a good concentration makes your pet's blood toxic to insects without affecting your pet's health. The Afoxolaner is metabolized gradually to ensure that it remains in your pet's bloodstream in the appropriate concentration for a full 30 days.

When a flea or tick attempts to feast on your pet's blood, Afoxolaner acts on their Central Nervous System by impeding an important neurotransmitter, which causes instantaneous death. This means your pet receives amazing protection in one tasty morsel! NexGard is a prescription-only medication, so talk to your veterinarian about using it for your pet.

Prescription Required

Ingredients

NexGard Chewables for Small Dogs 4-10 lbs
Active Ingredient (per tablet) Amount
Afoxolaner 11.3 mg
NexGard Chewables - For Medium Dogs 10.1-24 lbs
Active Ingredient (per tablet) Amount
Afoxolaner 28.3 mg
NexGard Chewables - For Large Dogs 24.1-60 lbs
Active Ingredient (per tablet) Amount
Afoxolaner 68 mg
NexGard Chewables - For Extra Large Dogs 60-121 lbs
Active Ingredient (per tablet) Amount
Afoxolaner 136 mg

Directions

View Nexgard Drug Facts Sheet.

NexGard is given orally once a month, at the minimum dosage of 1.14 mg/lb (2.5 mg/kg).

Dosing Schedule:
Body Weight Afoxolaner Per Chewable (mg) Chewables Administered
4.0 to 10.0 lbs 11.3 1 Orange
10.1 to 24.0 lbs 28.3 1 Blue
24.1 to 60.0 lbs 68 1 Purple
60.1 to 121.0 lbs 136 1 Red
Over 121.0 lbs Administer the appropriate combination of chewables

NexGard can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NexGard and resume a monthly dosing schedule.

Flea Treatment and Prevention:

Treatment with NexGard may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NexGard should continue the entire year without interruption.

To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.

Tick Treatment and Control:

Treatment with NexGard may begin at any time of the year (see Effectiveness).

Contraindications:

There are no known contraindications for the use of NexGard.

Warnings:

Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.

Precautions:

The safe use of NexGard in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures (see Adverse Reactions).

Adverse Reactions:

In a well-controlled US field study, which included a total of 333 households and 615 treated dogs (415 administered afoxolaner; 200 administered active control), no serious adverse reactions were observed with NexGard.

Over the 90-day study period, all observations of potential adverse reactions were recorded. The most frequent reactions reported at an incidence of > 1% within any of the three months of observations are presented in the following table. The most frequently reported adverse reaction was vomiting. The occurrence of vomiting was generally self-limiting and of short duration and tended to decrease with subsequent doses in both groups. Five treated dogs experienced anorexia during the study, and two of those dogs experienced anorexia with the first dose but not subsequent doses.

Dogs With Adverse Reactions.
Treatment Group
Afoxolaner Oral active control
N1 % (n=415 N2 % (n=200)
Anorexia 5 1.2 9 4.5
Vomiting (with and without blood 17 4.1 25 12.5
Dry/Flaky Skin 13 3.1 2 1.0
Diarrhea (with and without blood) 13 3.1 7 3.5
Lethargy 7 1.7 4 2.0

1Number of dogs in the afoxolaner treatment group with the identified abnormality.

2Number of dogs in the control group with the identified abnormality.

In the US field study, one dog with a history of seizures experienced a seizure on the same day after receiving the first dose and on the same day after receiving the second dose of NexGard. This dog experienced a third seizure one week after receiving the third dose. The dog remained enrolled and completed the study. Another dog with a history of seizures had a seizure 19 days after the third dose of NexGard. The dog remained enrolled and completed the study. A third dog with a history of seizures received NexGard and experienced no seizures throughout the study.

To report suspected adverse events, for technical assistance or to obtain a copy of the MSDS, contact Merial at 1-888-637-4251 or www.merial.com/nexgard. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth.

Mode of Action:

Afoxolaner is a member of the isoxazoline family, shown to bind at a binding site to inhibit insect and acarine ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfer of chloride ions across cell membranes. Prolonged afoxolaner-induced hyperexcitation results in uncontrolled activity of the central nervous system and death of insects and acarines. The selective toxicity of afoxolaner between insects and acarines and mammals may be inferred by the differential sensitivity of the insects and acarines' GABA receptors versus mammalian GABA receptors.

Effectiveness:

In a well-controlled laboratory study, NexGard began to kill fleas four hours after initial administration and demonstrated >99% effectiveness at eight hours. In a separate well-controlled laboratory study, NexGard demonstrated 100% effectiveness against adult fleas 24 hours post-infestation for 35 days, and was ≥93% effective at 12 hours post infestation through Day 21, and on Day 35. On Day 28, NexGard was 81.1% effective 12 hours post-infestation. Dogs in both the treated and control groups that were infested with fleas on Day 1 generated flea eggs at 12 and 24 hours post-treatment (0-11 eggs and 1-17 eggs in the NexGard treated dogs, and 4-90 eggs and 0-118 eggs in the control dogs, at 12 and 24-hours, respectively). At subsequent evaluations post infestation, fleas from dogs in the treated group were essentially unable to produce any eggs (0-1 eggs) while fleas from dogs in the control group continued to produce eggs (1-141 eggs).

In a 90-day US field study conducted in households with existing flea infestations of varying severity, the effectiveness of NexGard against fleas on the Day 30, 60 and 90 visits compared with baseline was 98.0%, 99.7%, and 99.9%, respectively.

Collectively, the data from the three studies (two laboratory and one field) demonstrate that NexGard kills fleas before they can lay eggs, thus preventing subsequent flea infestations after the start of treatment of existing flea infestations.

In well-controlled laboratory studies, NexGard demonstrated >97% effectiveness against Dermacentor variabilis, >94% effectiveness against Ixodes scapularis, and >93% effectiveness against Rhipicephalus sanguineus, 48 hours post-infestation for 30 days. At 72 hours post-infestation, NexGard demonstrated >97% effectiveness against Amblyomma americanum for 30 days.

Animal Safety:

In a margin of safety study, NexGard was administered orally to 8 to 9-week-old Beagle puppies at 1, 3, and 5 times the maximum exposure dose (6.3 mg/kg) for three treatments every 28 days, followed by three treatments every 14 days, for a total of six treatments. Dogs in the control group were sham-dosed. There were no clinically-relevant effects related to treatment on physical examination, body weight, food consumption, clinical pathology (hematology, clinical chemistries, or coagulation tests), gross pathology, histopathology or organ weights. Vomiting occurred throughout the study, with a similar incidence in the treated and control groups, including one dog in the 5x group that vomited four hours after treatment.

In a well-controlled field study, NexGard was used concomitantly with other medications, such as vaccines, anthelmintics, antibiotics (including topicals), steroids, NSAIDS, anesthetics, and antihistamines. No adverse reactions were observed from the concomitant use of NexGard with other medications.

Storage

Store at or below 30°C (86°F) with excursions permitted up to 40°C (104°F).

FAQ

If a dose is missed, administer the usual dose of NexGard Chewables and resume a monthly dosing schedule.
NexGard Chewables require a prescription. Give the appropriate dosage based on your dog's weight. (See How to Use). If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration redose with another full dose. NexGard Chewables can be administered with or without food. NexGard Chewables should be administered all year round. Treat all the pets in your home to reduce the risk of a flea infestation.
The most frequently reported adverse reactions include vomiting, dry/flaky skin, diarrhea, lethargy, and lack of appetite. The occurrence of vomiting was generally self-limiting and of short duration and tended to decrease with subsequent doses. There are no known contraindications for the use of NexGard Chewables.
Seek emergency veterinary medical treatment.
Avoid giving NexGard Chewables if your pet is pregnant, lactating or has a known history of seizures.
There are no known contraindications for the use of NexGard Chewables.
The active ingredient in NexGard Chewables is Afoxolaner. NexGard Chewables kill adult fleas and are indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of the American dog tick (Dermacentor variabilis), black-legged (deer) tick (Ixodes scapularis) and Lone star tick (Amblyomma americanum) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month.
Tell your veterinarian if your dog is pregnant, lactating or has a history of seizures. The safe use of NexGard Chewables in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures.
NexGard also kills the Lone Star tick, Black-legged tick, American Dog tick and Brown dog tick.
NexGard (afoxolaner) is safe and effective for use in puppies 8 weeks of age or older, weighing 4 pounds or more.
In a study, NexGard killed 100% of fleas within 24 hours.
NexGard stimulates the flea's nervous system, causing them to rise to the top of your dog's haircoat as they die.
Two years from the date of manufacture. You can locate the expiration date on the outside of the package of NexGard.
Because NexGard is an oral product, swimming or bathing has no effect on NexGard. Your dog's coat can get wet immediately after taking NexGard.
In a well-controlled field study, NexGard was used concomitantly with other medications, such as vaccines, anthelmintics, antibiotics (including topicals), steroids, nonsteroidal anti-inflammatory drugs (NSAIDs), anesthetics, and antihistamines.
NexGard is safe and effective in any breed of dog when used as directed.
No. NexGard should be used on dogs only.
Don't re-administer NexGard before the month is through. It keeps working for a full 30 days.
The most commonly reported adverse reactions found in NexGard for Dogs include vomiting, itching, diarrhea, lethargy and lack of appetite. Use with caution in dogs with a history of seizures.

Reviews

Review Summary
4.7
49 Reviews
5
78% (38)
4
20% (10)
3
0% (0)
2
2% (1)
1
0% (0)
100% Recommend this product (49 of 49 responses)
By Krystal
Claremont, CA
Great Product
July 2, 2020
Works great on my dog. Keeps all the ticks and fleas away with zero side effects for my pup.
By DP
Florida
Good Price
June 29, 2020
I have been getting this product from the Vet this was a better price however I would rather give the business to the local economy. will buy from Vet next time
By Von
WA
Works well
June 24, 2020
Nexgard was my pets vet recommendation. I needed an oral medication because we have a toddler in the house. But the choice was difficult as I have an Aussie, a Chihuahua,and a lab mix. I wanted something that was safe for the Aussie. This fits the bill.
By Terry
Northborough, MA
Great price & quick delivery!
June 24, 2020
Placed my first order with Entirely Pets, and was impressed with the discount and the quick delivery!
By Fran
South Padre Island
Awesome product
February 13, 2020
Only flea med Iā€™ve seen results from. Quick shipment! Thanks.
By Angie
Minnesota
Product is great customer service isn’t
January 29, 2020
I constantly responded to emails and it was evident they never check their customer service email. Until I called no one reached out to my vet for the prescription.
By Daisy
Stockton, CA
Terrific Service!
January 24, 2020
This was the first time I used this service. I have used NexGard and HeartGard for my dog and am very pleased with the product and now I found a service with good prices and excellent service. I will continue with this company if they continue their promotions.
ProsExcellent service and promotion prices
By Gail G.
IL
Best company!
September 19, 2019
This medication was the most reasonable I found and came quickly
By jw
CO
medicine was smashed
August 11, 2019
I'm thrilled to be able to give my dog a chewable and he likes it, but was disappointed that the first one I opened was in crumbled. Hoping the next 2 are intact! Don't know if it works but here's hoping!
ProsArrived quickly & good price.
Consnot a whole chew:(
By DougB
KS
Seams to be working well.
August 5, 2019
No negative side effects observed. Will continue to use Nexgard for my 10 month old Husky pup.
By Cindy
VA
No Fleas!
July 14, 2019
NexGard works great. I haven't seen any fleas on my dog since I have been using it.
By Beth
Madison, CT
It actually works!
February 1, 2019
My Vet introduced me to this product with my last German Shepard. Even after using other products, he still got ticks. NexGard....No Ticks in sight! You know that they get the whole dosage unlike the topical products. And to top it off---my dog loves to eat the "treat"!!
ProsKnown dosage Product works
ConsNone
By Kim
San Diego
Excellent price and excellent service!
January 5, 2019
Best price and quick service.
By Gail
Lake Elsinore
Good Product
December 28, 2018
Received what I ordered in a timely manner. Willing to help with obtaining the prescription.
By Stu
Manhattan
works fine. insects are no where to be seen
December 28, 2018
product does what it claims. the only downside is that my dog feels ill for the day, after taking this pill
By Kevin
San Diego
Excellent Product. Stellar Service!
December 12, 2018
NexGuard protects our dog with protection against both fleas and ticks. And, it doesnā€™t hurt hurt his stomach as has been the case with a previous flea medication.

Thsnk you to the pharmacy team for providing quick and efficient service.
By Mindy b.
De Soto MO
Flea Protection for canines
November 15, 2018
Great treatment and protection year round by taking one great tasting pill monthly.
ProsWorks well. Easy to give monthly
ConsRather expensive but well worth it for my sweet fur babies
By Taylor
Virginia
Will be ordering again if the issue arises!
November 7, 2018
AMAZING. Cannot use another word to describe! The day after I gave my dog this med, there was no itching. He was able to relax, without flea worry!
Merchant Response:Hi Taylor, The Nexard chewables are perfect for killing and repelling fleas. Be sure to let us know if you need to order 3 or 6 month doses.
By Dog M.
Virginia
Great price, right product!
October 4, 2018
Saved time and money by using your website. Fast and easy, the savings are significant.
ProsSavings. Convenient. Carry a full selection of brands and products.
By Karen
San Diego, CA
NexGard, it works!
August 31, 2018
This is the only flea medicine that works for my dog. I never see a flea on my dog Max. I will continue to use this to keep him flea free.
ProsHe enjoys taking this as if it were a treat.
By jjy55
Soquel, CA
Our Dog Loves These Chews
August 28, 2018
I actually bought NexGard through HeartlandVetSupply.com and my order was referred to Entirely Pets Pharmacy. I never had a problem doing this and received my order in a timely manner after I mailed my prescription to them. I found the pricing to be excellent especially if you use the discount for purchasing it online. I have no hesitation in purchasing NexGard this way.
Merchant Response:Fantastic! NexGard is a great product. Cheers!
By Kiz
Rocklin, CA
Easy to give
August 5, 2018
So much prefer this to yucky topicals for my dogs. Plus they love them!
By Robin
New York
Quick & Easy
June 3, 2018
Ordering through Entirely pets pharmacy was not only quick and easy, but saved me quite a bit of money. Prices are much lower than buying through my Vet.
By Bill
Palm Coast Fl
Love it!
June 1, 2018
Sweet Pea chews it right up! Guess she thinks it a 'treat'!
By tere
Tampa
Good price for vet recommended product for ticks.
May 5, 2018
My little guy was getting ticks everyday. It seems like the product works. He seems a little subdued for a day or two after taking it.
ProsNothing to apply, he is happy to eat it up.
By Beth
CA
Product as expected
April 29, 2018
Good product and product arrived after several weeks. I guess i wasn't aware that they would need to call/fax the vet in order to get a prescription. I thought I could just order the product and get it within a few days. Start early is my advice.
Merchant Response:We have since perfected our methods and prescriptions are getting approvals inside 3 days. We will continue to make improvements to get NexGard delivered as soon as possible!
By M C.
Pgh. Pa.
nexgard
April 28, 2018
Got med. in timely manor no problems
By Jill
Texas
Good Rx POOR CUSTOMER SERVICE
April 27, 2018
The Rx is fine but will never purchase from EntirelyPets Pharmacy again due to their extremely poor customer service.
By Eden B.
Ohio
NetGuard Chews
April 9, 2018
I have two dogs so I have to order one 3-pack and 1-1 pack. They arrive together and are easy to order once your vet has sent the prescription.
ProsIt so easy to order and if you call the people are very helpful.
ConsI don't know any cons!
By Scott P.
SF, CA
my experience
December 14, 2017
This was our first attempt to buy pet meds via the internet ... loved it! Entirely Pets was so helpful and great through the process, can't thank you enough and I will recommend you all to everyone.
Regards,
Scott
Merchant Response:Thank you for the great feedback Scott. We're glad we were able to get you your NexGard, don't hesitate to let us know when you're ready for a refill!

Customers Who Bought Also Bought