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NexGard Flea & Tick Chewables for Dogs

NexGard Flea & Tick Chewables for Dogs

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  • Description
  • Ingredients
  • Directions
  • FAQ
  • Reviews


NexGard Flea & Tick Chewables for dogs is a brand new, revolutionary flea and tick preventative from the makers of Frontline®, the #1 choice of veterinarians. It's the first flea and tick killer of its kind because it comes in a yummy, beef-flavored soft chew that protects your dog from flea and tick infestations for a full 30 days. That means you no longer have to worry about messy topicals or accidentally washing it off your dog while bathing! It can also be taken alongside your dog's heartworm medication without interruption for your convenience.

NexGard keeps your pet protected from adult fleas by killing them before they have a chance to lay eggs, which reduces the possibility of a flea infestation. It also kills the American dog tick, which decreases the risk of your pet developing a deadly tick-borne disease.


NexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of Black-legged tick (Ixodes scapularis), American Dog tick (Dermacentor variabilis), Lone Star tick (Amblyomma americanum), and Brown dog tick (Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month.

Key Benefits

  • First-ever flea and tick preventive from the makers of Frontline that comes in a tasty beef-flavored chew
  • No messier topical preventives, and no more worrying about washing off your dog's flea protection
  • Safe, effective, FDA-approved, and lasts for 30 days
  • Can be taken alongside heartworm medication

How It Works

NexGard contains a brand new ingredient not used in any other flea and tick protection. Afoxolaner, the ingredient in NexGard, is rapidly absorbed into your pet's bloodstream where a good concentration makes your pet's blood toxic to insects without affecting your pet's health. The Afoxolaner is metabolized gradually to ensure that it remains in your pet's bloodstream in the appropriate concentration for a full 30 days.

When a flea or tick attempts to feast on your pet's blood, Afoxolaner acts on their Central Nervous System by impeding an important neurotransmitter, which causes instantaneous death. This means your pet receives amazing protection in one tasty morsel! NexGard is a prescription-only medication, so talk to your veterinarian about using it for your pet.


NexGard is for use in dogs only. The most frequently reported adverse reactions to include vomiting, dry/flaky skin, diarrhea, lethargy, and lack of appetite. The safe use of NexGard in pregnant, breeding or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures.

Prescription Required

NADA 141-406


WeightAfoxolaner (per chew)
4 - 10 lbs (Small Dogs)11.3 mg
10.1 - 24 lbs (Medium Dogs)28.3 mg
24.1 - 60 lbs (Large Dogs)68 mg
60.1 - 121 lbs (Extra Large Dogs)136 mg


View Nexgard Drug Facts Sheet.

Dosage and Administration

NexGard is given orally once a month, at the minimum dosage of 1.14 mg/lb (2.5 mg/kg).

Quick Tips

  • NexGard can be administered with or without food.
  • Treatment with NexGard may begin at any time of the year.
  • To minimize the likelihood of flea re-infestation, it is important to treat all animals within a household with an approved flea control product.
  • If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NexGard and resume a monthly dosing schedule.

Dosage Table

Body Weight Chewables Administered
4.0 to 10.0 lbs One (Orange)
10.1 to 24.9 lbs One (Blue)
24.1 to 60.0 lbs One (Purple)
60.1 to 121.0 lbs One (Red)
Over 121.0 lbs Administer the appropriate combination of chewables

Storage Directions

Store at or below 30°C (86°F) with excursions permitted up to 40°C (104°F). Keep away from children and pets.


Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.

Possible Side Effects

The most frequently reported adverse reaction was vomiting. The occurrence of vomiting was generally self-limiting and of short duration and tended to decrease with subsequent doses. There are no known contraindications for the use of NexGard.


There are no known contraindications for the use of NexGard.


View NexGard Chewables official FAQ.

How long does it take Nexgard to kill fleas?

NexGard has been shown to kill fleas four hours after initial administration and demonstrated >99% effectiveness at eight hours. In a separate well-controlled laboratory study, Nexgard demonstrated 100% effectiveness against adult fleas 24 hours post-infestation for 35 days.

Does Nexgard have an expiration date?

You can locate the expiration date on the outside of the package of Nexgard.

How long should I wait to bathe my dog (or let my dog go swimming) after giving Nexgard?

Because Nexgard is an oral product, swimming or bathing has no effect on it. Your dog's coat can get wet immediately after a dose.

Is Nexgard safe to use on any breed of dog?

It is safe and effective in any breed of dog when used as directed.

Can I administer Nexgard more than once a month?

Don't re-administer Nexgard before the month is through. It keeps working for a full 30 days.


Review Summary
45 Reviews
78% (35)
20% (9)
0% (0)
2% (1)
0% (0)
100% Recommend this product (45 of 45 responses)
By Fran
South Padre Island
Awesome product
February 13, 2020
Only flea med I’ve seen results from. Quick shipment! Thanks.
By Angie
Product is great customer service isn’t
January 29, 2020
I constantly responded to emails and it was evident they never check their customer service email. Until I called no one reached out to my vet for the prescription.
By Daisy
Stockton, CA
Terrific Service!
January 24, 2020
This was the first time I used this service. I have used NexGard and HeartGard for my dog and am very pleased with the product and now I found a service with good prices and excellent service. I will continue with this company if they continue their promotions.
ProsExcellent service and promotion prices
By Gail G.
Best company!
September 19, 2019
This medication was the most reasonable I found and came quickly
By jw
medicine was smashed
August 11, 2019
I'm thrilled to be able to give my dog a chewable and he likes it, but was disappointed that the first one I opened was in crumbled. Hoping the next 2 are intact! Don't know if it works but here's hoping!
ProsArrived quickly & good price.
Consnot a whole chew:(
By DougB
Seams to be working well.
August 5, 2019
No negative side effects observed. Will continue to use Nexgard for my 10 month old Husky pup.
By Cindy
No Fleas!
July 14, 2019
NexGard works great. I haven't seen any fleas on my dog since I have been using it.
By Beth
Madison, CT
It actually works!
February 1, 2019
My Vet introduced me to this product with my last German Shepard. Even after using other products, he still got ticks. NexGard....No Ticks in sight! You know that they get the whole dosage unlike the topical products. And to top it off---my dog loves to eat the "treat"!!
ProsKnown dosage Product works
By Kim
San Diego
Excellent price and excellent service!
January 5, 2019
Best price and quick service.
By Gail
Lake Elsinore
Good Product
December 28, 2018
Received what I ordered in a timely manner. Willing to help with obtaining the prescription.
By Stu
works fine. insects are no where to be seen
December 28, 2018
product does what it claims. the only downside is that my dog feels ill for the day, after taking this pill
By Kevin
San Diego
Excellent Product. Stellar Service!
December 12, 2018
NexGuard protects our dog with protection against both fleas and ticks. And, it doesn’t hurt hurt his stomach as has been the case with a previous flea medication.

Thsnk you to the pharmacy team for providing quick and efficient service.
By Mindy b.
De Soto MO
Flea Protection for canines
November 15, 2018
Great treatment and protection year round by taking one great tasting pill monthly.
ProsWorks well. Easy to give monthly
ConsRather expensive but well worth it for my sweet fur babies
By Taylor
Will be ordering again if the issue arises!
November 7, 2018
AMAZING. Cannot use another word to describe! The day after I gave my dog this med, there was no itching. He was able to relax, without flea worry!
Merchant Response:Hi Taylor, The Nexard chewables are perfect for killing and repelling fleas. Be sure to let us know if you need to order 3 or 6 month doses.
By Dog M.
Great price, right product!
October 4, 2018
Saved time and money by using your website. Fast and easy, the savings are significant.
ProsSavings. Convenient. Carry a full selection of brands and products.
By Karen
San Diego, CA
NexGard, it works!
August 31, 2018
This is the only flea medicine that works for my dog. I never see a flea on my dog Max. I will continue to use this to keep him flea free.
ProsHe enjoys taking this as if it were a treat.
By jjy55
Soquel, CA
Our Dog Loves These Chews
August 28, 2018
I actually bought NexGard through and my order was referred to Entirely Pets Pharmacy. I never had a problem doing this and received my order in a timely manner after I mailed my prescription to them. I found the pricing to be excellent especially if you use the discount for purchasing it online. I have no hesitation in purchasing NexGard this way.
Merchant Response:Fantastic! NexGard is a great product. Cheers!
By Kiz
Rocklin, CA
Easy to give
August 5, 2018
So much prefer this to yucky topicals for my dogs. Plus they love them!
By Robin
New York
Quick & Easy
June 3, 2018
Ordering through Entirely pets pharmacy was not only quick and easy, but saved me quite a bit of money. Prices are much lower than buying through my Vet.
By Bill
Palm Coast Fl
Love it!
June 1, 2018
Sweet Pea chews it right up! Guess she thinks it a 'treat'!
By tere
Good price for vet recommended product for ticks.
May 5, 2018
My little guy was getting ticks everyday. It seems like the product works. He seems a little subdued for a day or two after taking it.
ProsNothing to apply, he is happy to eat it up.
By Beth
Product as expected
April 29, 2018
Good product and product arrived after several weeks. I guess i wasn't aware that they would need to call/fax the vet in order to get a prescription. I thought I could just order the product and get it within a few days. Start early is my advice.
Merchant Response:We have since perfected our methods and prescriptions are getting approvals inside 3 days. We will continue to make improvements to get NexGard delivered as soon as possible!
By M C.
Pgh. Pa.
April 28, 2018
Got med. in timely manor no problems
By Jill
April 27, 2018
The Rx is fine but will never purchase from EntirelyPets Pharmacy again due to their extremely poor customer service.
By Eden B.
NetGuard Chews
April 9, 2018
I have two dogs so I have to order one 3-pack and 1-1 pack. They arrive together and are easy to order once your vet has sent the prescription.
ProsIt so easy to order and if you call the people are very helpful.
ConsI don't know any cons!
By Scott P.
my experience
December 14, 2017
This was our first attempt to buy pet meds via the internet ... loved it! Entirely Pets was so helpful and great through the process, can't thank you enough and I will recommend you all to everyone.
Merchant Response:Thank you for the great feedback Scott. We're glad we were able to get you your NexGard, don't hesitate to let us know when you're ready for a refill!
By Dog l.
To be please or not to be pleased...that is the question.
December 8, 2017
Pleased that they stock the item and shipment quick. Not so pleased because I don't understand why a little tiny chew costs so much. Overall tho...pleased.
Merchant Response:Hello, thank you for your feedback. We're sorry the NexGard is a little pricey, although we do strive to offer the best prices!
ProsFast service, quality product.
ConsPricey for a small pill.
By Mary
No fleas
December 6, 2017
My two German Shepherds have never had fleas in Ten years..Great product.
By Bonnie B.
Bellingham, WA
Edible flea treatment
November 22, 2017
This product Is so much easier to deal with than Frintline, my heretofore preferred flea treatment. The dogs eat it with relish. It vanishes. No more wet doggie necks that I would inevitably pet before the topical product dried and get some nasty stuff on my hands......what I mostly disliked about Frontline.

So flea treatment has evolved from collars to topical to edibles. I say hooray!
Merchant Response:Hi Bonnie, so good to hear the NexGard is working so well for you and your dogs and they're eating it with no problem. Hooray for not getting any nasty stuff on your hands!
By Mac
Lewes, DE
NexGard Chews 24.1 - 60lbs (6mnth supply) Purple
October 1, 2017
Works well for my German shepherd
Merchant Response:Thanks for the feedback Mac, glad to hear it's working well for you GSD!

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