Cystorelin Sterile Solution

CYSTORELIN is indicated for the treatment of ovarian follicular cysts in dairy cattle. Ovarian cysts are non-ovulated follicles with incomplete luteinization which result in nymphomania or irregular estrus. Historically, cystic ovaries have responded to an exogenous source of luteinizing hormone (LH) such as human chorionic gonadotropin. CYSTORELIN initiates release of endogenous LH to cause ovulation and luteinization.

CYSTORELIN was the first-selling GnRH productapproved by the FDA for treatment of cystic ovaries in cattle. CYSTORELIN is labeled for use in combination with SYNCHSURE to synchronize estrous cycles to allow for fixed-time artificial insemination (FTAI) in lactating dairy cows and beef cows.

Features and Benefits
• EFFICIENT: CYSTORELIN is available in a 10-bottle carton with 15 doses per bottle. That gives you more doses in one bottle than any other GnRH. A flexible 5-dose bottle is also available.
• EFFECTIVE: In a study,¹ CYSTORELIN induced the highest peak and highest average LH responses as well as the highest ovulatory response of 95% compared to Fertagyl® (gonadorelin) and Factrel® (gonadorelin hydrochloride).
• EASY TO USE:
• CYSTORELIN has no milk withholding and no meat withdrawal.
• Once opened, CYSTORELIN has a 6-month shelf life, and is stored at or below 77°F.

• 100 mcg (2 mL) per cow via intravenous or intramuscular injection.
• Store at or below 77°F (25°C). Brief excursions to 86°F (30°C) are permitted.

IMPORTANT SAFETY INFORMATION FOR CYSTORELIN: DO NOT USE IN HUMANS. KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.

IMPORTANT SAFETY INFORMATION FOR SYNCHSURE: FOR ANIMAL USE ONLY, NOT FOR HUMAN USE. KEEP OUT OF REACH OF CHILDREN. Women of childbearing age, asthmatics, and persons with bronchial and other respiratory problems should exercise extreme caution when handling this product. In the early stages women may be unaware of their pregnancies. SYNCHSURE™ (cloprostenol sodium) is readily absorbed through the skin and may cause abortion and/or bronchospasms: direct contact with the skin should therefore be avoided. Accidental spillage on the skin should be washed off immediately with soap and water.