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Revolution for Dogs

Revolution for Dogs

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  • Description
  • Ingredients
  • Directions
  • FAQ
  • Reviews

Description

Revolution® (Selamectin) is a safe and simple monthly topical medication used to protect your dog or cat from heartworms, fleas, and ear mites. Revolution® (Selamectin) is also used on dogs for the treatment or prevention of fleas, the American Dog Tick, ear mites, and canine sarcoptic mange. When used on cats it is also used to treat or prevent fleas, ear mites, hookworms, and roundworms.

Key Benefits

  • Protects your pet from heartworms and fleas
  • Fights both internal and surface parasitic infections
  • Treats Sarcoptic mange in dogs
  • Treats and controls ear mites
  • Controls American Dog Tick infestation
  • Treats and controls roundworms and hookworms in cats
  • Only administered once a month
  • Safe and easy to use

Indication:

Revolution is recommended for use in dogs six weeks of age or older.

Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations. Revolution also is indicated for the treatment and control of sarcoptic mange (Sarcoptes scabiei) and for the control of tick infestations due to Dermacentor variabilis.

How It Works

Revolution works by penetrating the skin and entering your pet's bloodstream. Concentrations of selamectin, the active ingredient, in the tissue and bloodstream prevent heartworm disease. Selamectin also redistributes into the skin from the bloodstream and kills adult fleas, American dog ticks, and ear mites, and prevents flea eggs from hatching. It is also an anthelmintic, which means it fights to expel parasitic worms. Parasites ingest the drug when they feed on the animal's blood.

Prescription Required

Ingredients

Revolution® (Selamectin) for Puppies/Kittens up to 5 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 15 mg
Revolution® (Selamectin) for Cats 5.1-15 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 45 mg
Revolution® (Selamectin) for Cats 15.1-22 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 60 mg
Revolution® (Selamectin) for Dogs 5.1-10 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 30 mg
Revolution® (Selamectin) for Dogs 10.1-20 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 60 mg
Revolution® (Selamectin) for Dogs 20.1-40 lbs:
Active Ingredients (per flavor tab) Amount
Milbemycin Oxime 120 mg
Revolution® (Selamectin) for Dogs 40.1-85 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 240 mg
Revolution® (Selamectin) for Dogs 85.1-130 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 360 mg

Directions

View Revolution product insert.

The recommended minimum dose is 2.7 mg selamectin per pound (6 mg/kg) of body weight. Administer the entire contents of a single dose tube (or two tubes used in combination for dogs weighing over 130 pounds) of Revolution topically in accordance with the following tables. (See Administration for the recommended treatment intervals.)

Dogs (lb) Package color mg per tube Potency (mg/mL) Administered volume (mL)
Up to 5 Mauve 15 mg 60 0.25
5.1-10 Purple 30 mg 120 0.25
10.1-20 Brown 60 mg 120 0.5
20.1-40 Red 120 mg 120 1.0
40.1-85 Teal 240 mg 120 2.0
85.1-130 Plum 360 mg 120 3.0

For dogs over 130 lbs use the appropriate combination of tubes.

Recommended for use in dogs 6 weeks of age and older and in cats 8 weeks of age and older.

Cats (lb) Package color mg per tube Potency (mg/mL) Administered volume (mL)
Up to 5 Mauve 15 mg 60 0.25
5.1-15 Blue 45 mg 60 0.75
15.1-22 Taupe 60 mg 60 1.0

For cats over 22 lbs use the appropriate combination of tubes.

Administration:

A veterinarian or veterinary technician should demonstrate or instruct the pet owner regarding the appropriatetechnique for applying Revolution topically to dogs and cats prior to first use. Firmly press the cap down to puncture the seal on the Revolution tube; a clicking sound will confirm that the cap has successfully punctured the seal. Remove the cap and check to ensure that the tip of the tube is open. To administer the product, part the hair on the back of the animal at the base of the neck in front of the shoulder blades until the skin is visible. Place the tip of the tube on the skin and squeeze the tube 3 or 4 times to empty its entire contents directly onto the skin in one spot. Keeping the tube squeezed, drag it away from the liquid and lift to remove. Check the tube to ensure that it is empty. Do not massage the product into the skin. Due to alcohol content, do not apply to broken skin. Avoid contact between the product and fingers. Do not apply when the haircoat is wet. Bathing or shampooing the dog 2 or more hours after treatment will not reduce the effectiveness of Revolution against fleas or heartworm. Bathing or shampooing the cat 2 hours after treatment will not reduce the effectiveness of Revolution against fleas. Bathing or shampooing the cat 24 hours after treatment will not reduce the effectiveness of Revolution against heartworm. Stiff hair, clumping of hair, hair discoloration, or a slight powdery residue may be observed at the treatment site in some animals. These effects are temporary and do not affect the safety or effectiveness of the product. Discard empty tubes in your ordinary household refuse.

Flea Control in Dogs and Cats

For the prevention and control of flea infestations, Revolution should be administered at monthly intervals throughout the flea season, starting one month before fleas become active. In controlled laboratory studies ›98% of fleas were killed within 36 hours. Results of clinical field studies using Revolution monthly demonstrated ›90% control of flea infestations within 30 days of the first dose. Dogs and cats treated with Revolution, including those with pre-existing flea allergy dermatitis, showed improvement in clinical signs associated with fleas as a direct result of eliminating the fleas from the animals and their environment.

If the dog or cat is already infested with fleas when the first dose of Revolution is administered, adult fleas on the animal are killed and no viable fleas hatch from eggs after the first administration. However, an environmental infestation of fleas may persist for a short time after beginning treatment with Revolution because of the emergence of adult fleas from pupae.

Heartworm Prevention in Dogs and Cats

For the prevention of heartworm disease, Revolution must be administered on a monthly basis. Revolution may be administered year-round or at least within one month after the animal's first exposure to mosquitoes and monthly thereafter until the end of the mosquito season. The final dose must be given within one month after the last exposure to mosquitoes. If a dose is missed and a monthly interval between dosing is exceeded then immediate administration of Revolution and resumption of monthly dosing will minimize the opportunity for the development of adult heartworms. When replacing another heartworm preventive product in a heartworm disease prevention program, the first dose of Revolution must be given within a month of the last dose of the former medication.

Selamectin, the active ingredient in Revolution, is a macrocyclic lactone compound. These compounds effectively prevent the development of adult heartworms when administered to dogs and cats within one month of exposure to infective (L3) Dirofilaria immitis larvae. Efficacy of macrocyclic lactones decreases below 100% in dogs, however, if first administered ›2 months after exposure to infective larvae. Thus, in heartworm endemic regions, delaying initiation of heartworm prevention using Revolution beyond 2 months of first exposure to infective larvae (e.g., starting puppies and kittens at ›8 weeks of age), or gaps of ›2 months in the administration of Revolution during periods of heartworm transmission, increases the risk of the animal acquiring heartworms. Animals with unknown heartworm history that test negative for heart-worms prior to the initiation of Revolution may be harboring pre-patent infections at the time Revolution was started. Testing such animals 3-4 months after initiation of Revolution would be necessary to confirm their negative heartworm status.

At the discretion of the veterinarian, cats ≥6 months of age may be tested to determine the presence of existing heartworm infections before beginning treatment with Revolution. Cats already infected with adult heartworms can be given Revolution monthly to prevent further infections.

Ear Mite Treatment in Dogs and Cats

For the treatment of ear mite (O. cynotis) infestations in dogs and cats, Revolution should be administered once as a single topical dose. A second monthly dose may be required in some dogs. Monthly use of Revolution will control any subsequent ear mite infestations. In the clinical field trials ears were not cleaned, and many animals still had debris in their ears after the second dose. Cleansing of the infested ears is recommended to remove the debris.

Sarcoptic Mange Treatment in Dogs

For the treatment of sarcoptic mange (S. scabiei) in dogs, Revolution should be administered once as a single topical dose. A second monthly dose may be required in some dogs. Monthly use of Revolution will control any subsequent sarcoptic mange mite infestations. Because of the difficulty in finding sarcoptic mange mites on skin scrapings, effectiveness assessments also were based on resolution of clinical signs. Resolution of the pruritus associated with the mite infestations was observed in approximately 50% of the dogs 30 days after the first treatment and in approximately 90% of the dogs 30 days after the second monthly treatment.

Tick Control in Dogs

For the control of tick (Dermacentor variabilis) infestations in dogs, Revolution should be administered on a monthly basis. In heavy tick infestations, complete efficacy may not be achieved after the first dose. In these cases, one additional dose may be administered two weeks after the previous dose, with monthly dosing continued thereafter.

Nematode Treatment in Cats

For the treatment and control of intestinal hookworm (A. tubaeforme) and roundworm (T. cati) infections, Revolution should be applied once as a single topical dose.

Safety:

Revolution has been tested safe in over 100 different pure and mixed breeds of healthy dogs and over 15 different pure and mixed breeds of healthy cats, including pregnant and lactating females, breeding males and females, puppies six weeks of age and older, kittens eight weeks of age and older, and avermectin sensitive collies. A kitten, estimated to be 5-6 weeks old (0.3 kg), died 8 ½ hours after receiving a single treatment of Revolution at the recommended dosage. The kitten displayed clinical signs which included muscle spasms, salivation and neurological signs. The kitten was a stray with an unknown history and was malnourished and underweight (see Warnings).

Dogs: In safety studies, Revolution was administered at 1, 3, 5, and 10 times the recommended dose to six-week-old puppies, and no adverse reactions were observed. The safety of Revolution administered orally also was tested in case of accidental oral ingestion. Oral administration of Revolution at the recommended topical dose in 5 to 8-month-old beagles did not cause any adverse reactions. In a pre-clinical study selamectin was dosed orally to ivermectin-sensitive collies. Oral administration of 2.5, 10, and 15 mg/kg in this dose escalating study did not cause any adverse reactions; however, eight hours after receiving 5 mg/kg orally, one avermectin-sensitive collie became ataxic for several hours, but did not show any other adverse reactions after receiving subsequent doses of 10 and 15 mg/kg orally. In a topical safety study conducted with avermectin-sensitive collies at 1, 3 and 5 times the recommended dose of Revolution, salivation was observed in all treatment groups, including the vehicle control. Revolution also was administered at 3 times the recommended dose to heartworm infected dogs, and no adverse effects were observed.

Cats: In safety studies, Revolution was applied at 1, 3, 5, and 10 times the recommended dose to six-week-old kittens. No adverse reactions were observed. The safety of Revolution administered orally also was tested in case of accidental oral ingestion. Oral administration of the recommended topical dose of Revolution to cats caused salivation and intermittent vomiting. Revolution also was applied at 4 times the recommended dose to patent heartworm infected cats, and no adverse reactions were observed. In well-controlled clinical studies, Revolution was used safely in animals receiving other frequently used veterinary products such as vaccines, anthelmintics, antiparasitics, antibiotics, steroids, collars, shampoos and dips.

FAQ

Revolution is a prescription medication applied topically once a month. Do not use Revolution on puppies under 6 weeks of age or kittens under 8 weeks of age. According to the product literature, Revolution is safe for use on pregnant or lactating dogs and cats.

Revolution is a topical parasiticide applied once a month for the prevention of heartworm disease in dogs and cats. Revolution is also used on dogs for the treatment or prevention of fleas, the American Dog Tick, ear mites, and canine sarcoptic mange. When used on cats it is also used to treat or prevent fleas, ear mites, hookworms, and roundworms. It is recommended that heartworm prevention be used year-round. Revolution may also be used for purposes other than those listed in this guide.

Tell your veterinarian if your pet has ever had an allergic reaction to the medication.

Apply Revolution exactly as directed by your veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. Revolution is available as unit of use applicator tubes containing the specific amount of medication based on the weight of your pet. Revolution is available as a 15mg/0.25ml puppy/kitten dose for puppies older than 6 weeks and kittens older than 8 weeks weighing up to 5 lbs. Revolution is also available for cats 5.1-15 lbs (45mg/0.75ml), 15.1-22 lbs (60mg/1ml), and for dogs 5.1-10 lbs (30mg/0.25ml), dogs 10.1-20 lbs (60mg/0.5ml), 20.1-40 lbs (120mg/1 ml), 40-1-85 lbs (240mg/2 ml) and 85.1-130 lbs (360mg/3ml). For dogs over 130 lbs use the appropriate combination of tubes. The entire contents of the tube should be used. Do not split the contents as the accuracy of the dose and effectiveness of the medication cannot be assured. Bathing or shampooing your pet 2 or more hours after treatment will not reduce the effectiveness of Revolution. Keep this medication away from children and pets.

Give the missed dose as soon as you remember. Do not give a double dose of the medication.

Seek emergency veterinary medical treatment. Symptoms of overdose, while rare, may include salivation and lack of coordination, as well as symptoms listed below as side effects.

Because humans can contract hookworms from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the house and to not feed your pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended. Do not use on sick, weak, or underweight animals. Do not apply to wet hair. Dogs should be tested for heartworms prior to using Revolution. In humans, Revolution may be irritating to skin and eyes. Wash hands thoroughly after applying Revolution to your pet.

Side effects of Revolution that may occur include temporary hair loss at the site of application, loss of appetite, drooling, vomiting, diarrhea, drowsiness, rapid breathing, increased heart rate, and muscle tremors.

Do not apply Revolution to your pet if already giving an alternate heartworm medication. When switching from another heartworm medication, begin Revolution when the next dose of the heartworm medication is due.

Your pharmacist has additional information about Revolution written for health professionals that you may read.

Revolution kills adult fleas and prevents flea eggs from hatching. You may occasionally see a few fleas on dogs or cats treated with Revolution but more than 98% of adult fleas are killed within 36 hours.

Immature stages of the flea called pupae may be present in your petsí environment (yard, flooring, carpet, bedding, etc.). These pupae are not killed by parasiticides (including Revolution) and as such may emerge as adult fleas. These adult fleas may hop onto your pet at anytime. They must be exposed to Revolution on your dog or cat before being killed. It can take from 3Ė5 weeks (or longer depending on environmental conditions) for most fleas to complete their 4-stage life cycle (egg, larvae, pupae, and adult) and reach the adult stage before being seen on your pet. Due to the presence of immature flea stages in infested environments it can take up to 2 to 3 monthly applications for Revolution to maximally control the infestation of fleas in the environment. Once the flea population is controlled you will be less likely to see fleas.

Revolution controls tick infestations only due to the American Dog Tick (Dermacentor variabilis), a tick commonly found on dogs. There are other common species of ticks that are not killed or controlled by Revolution. Your veterinarian can recommend appropriate products to control or kill ticks common to your area. For the control of the American Dog Tick, Revolution should be applied once a month; however, your veterinarian may recommend a second administration applied 14 days after the first dose if your dog has a heavy tick infestation and/or recommend additional tick control methods. It may take up to 5 days to kill the majority of ticks on your dog.

In well-controlled clinical studies, Revolution was used safely in dogs and cats receiving other veterinary products such as vaccines, anthelmintics, antiparasitics, antibiotics, steroids, collars, shampoos and dips.

Tell your veterinarian about all medicines you have given your dog or cat in the past, and any medicines that you are planning to use with Revolution. This should include other medicines that you can get without a prescription. Your veterinarian may want to check that all of your dogís or catís medicines can be given together.

Reviews

Review Summary
4.9
35 Reviews
5
91% (32)
4
6% (2)
3
0% (0)
2
3% (1)
1
0% (0)
100% Recommend this product (35 of 35 responses)
By Fairy M.
San Diego
Excellent
July 5, 2018
My dog is allergic to beef products and many heartworm meds contain beef. This topical is an excellent value because it is a heartworm med as well as a flea product. My sheltie tolerates it well. I also haven't seen or heard of any horror stories regarding this full spectrum product as I've heard and seen with others.
Merchant Response:You are quite the pet parent! We are happy to help and too glad to fill your pet scripts Fairy Dog Mother.
ProsNo bovine source as with edible heartworm med Flea and heartworm preventative
By I M.
Farmington Hills Michigan
Good product
September 6, 2020
Been using for at least six years and have never had a problem. Will continue using this product.
ConsNone
By Mary A.
Bend oregon
Revolution
July 4, 2020
Well - we were thrilled to find a heart worm product that we didnít have to shove down our dogs throat! However, directions were not clear about annual dosages and we werenít sure if we would be reminded when the next dose was due! I placed a call to find out but didnít receive a response.
ProsGood product!
ConsPoor instructions!
By Diane N.
Lakeville, MN
Revolution Prescription for Pet
June 25, 2020
After calling both the Entirely Pets Pharmacy and my veterinarian twice, the pharmacy finally called my vet and got a verbal authorization. The pharmacies excuse was they had issues with the vetís fax number. This ordeal took about 2 1/2 weeks to complete. I was glad that I had a monthís worth of prescription left while working this issue. If I continue using this pharmacy I now know that I have to give some lead time.
Merchant Response:Diane, we are working to better this process every day. We appreciate your feedback.
ProsThe pharmacy personnel were pleasant to work with. I finally received the prescription for my pet.
ConsPharmacy was a hassle to work with.
By Dick
Lake in the Hills, IL
Good and easy to use.
April 2, 2020
Good and easy to use
By JUDITH
SEBASTIAN FL
Revolution topical
March 24, 2020
I have an Italian greyhound with not a lot of fur. I was concerned that it may irritate his skin. It does not! Great! After the 3rd treatment he no longer has fleas nor in the house! I had a flea infestation in yard. Product is great stopping the fleas! It has heartworm med in it also. When he gets tested in may I will find out if it works on that! Good price also. I am continuing to use this product!
By Dogman
Wasington D.C. & Utal
SBD K-9 Unit
January 30, 2020
So far so good. This product covers heart worm, fleas and ticks.
ConsI guess the only way to tell if it works is that there are no problems -- right?
By Barbara
California
super easy
January 30, 2020
Very easy to apply and effective.
By Anita
Sheffield, VT
Revolution
November 3, 2019
Purchased the 6 pack version as a new customer. Supplied my vet information so they could obtain a prescription and I only had to wait for my shipment to be delivered. Very pleased with the purchase and I would purchase from these folks again.
Merchant Response:Hi Anita, I am so glad to hear that we were able to provide you with good customer service. I would like to thank you for shopping with our Pharmacy.
By Marge
Tucson, AZ
Revolution
September 25, 2019
Excellent product. Candy has been hear worm free and also tick, flea free since applying revolution monthly.
By dDanz
austin, texas
Great prices and efficent shipping
February 3, 2019
great prices, discount coupons sent via email and efficient, fast shipping
Prosgreat prices, discount coupons sent via email and efficient & fast shipping
Consnone that I can think of
By Jan
Macomb, MI
Great Job!
December 6, 2018
Ordering through Entirely Pets is always so quick and easy. Revolution is a great product. It is two medications in one. Our dog has allergies and our vet put him on Revolution to help. Not only is it for heart worm, flea and tick prevention, but also helps with his allergies. I like the two in one (heart worm AND flea/tick). Just one medication to give our dog. And it is cheaper not having to buy two prevention products. I highly recommend Revolution.
ProsGiving pet only one medication every month. Cheaper than buying heat worm and flea and tick prevention meds separately.
ConsNone
By Dave
Hamilton, Ohio
Great Product
November 10, 2018
We've used Revolution for quite a few years and haven't been disappointed in the results. It's a once a month product for fleas as well as a heartworm medication.
By Adrienne U.
Lake worth fl
Great price
October 26, 2018
Very easy to order and received in less than a week
ProsGreat price
ConsN/A
By Linda P.
Florida
Great Product
October 21, 2018
Been using Revolution for many years on all my dogs and cats.
ProsProtects against fleas, heartworms, ear mites, some types of ticks and one intestinal parasite (don't recall which one).
Consexpensive but you must keep in mind that in addition to flea prevention it also provides heartworm protection so no need to purchase heartworm preventive meds.
By Beatrix
Petaluma, CA
Excellent Product
August 30, 2018
Gets the job done with protecting for hear worm and fleas. Doesn't make my dog sick.
By Mary B.
Costa Mesa, CA
Delivery
August 29, 2018
Received product on time.
Always a pleasure to shop here.
Merchant Response:Mary, it's our pleasure. =)
By Moni
Austin, Tx
Good price
April 26, 2018
Received it quickly and exactly what ordered for a very good price.
ProsCovers everything in one application
ConsIt is a liquid you put on the back.
By Margaret C.
Tucson, Arizona
Revolution
March 15, 2018
Ordered online and received product fairly quickly as I had a prescription on file. Product well labeled and instructions clear. Great company
By Susan
Arizona
Great price
February 21, 2018
You have the best prices and fast shipping. Thank you...I know I will buy from you again
By BW
Hayward, CA
Fast, easy, and pricing is good!
January 20, 2017
Now, I do not have to spend my time on the weekend with my dog at Pet Expres to purchase this item. Also, the cost is cheaper!
ProsGreat service!
By Carol K.
Sublette, ILimois
Love the price
November 25, 2016
Exactly the same as the expense ones from our vet
By REX R.
Livingston
What a bargain!
November 13, 2016
When the sale started I bought 12 months! I have used this for years and have no fleas, ticks, or internal pests on my dogs. It's a great product at a great price.
By Judy
Las Cruces, NM
Very nice
September 30, 2016
Fast shippers and the price is always fair
By Ashley
Chicago
Just what I wanted
July 25, 2016
Great price
By Carol K.
Illinois
Great price for a great product
July 6, 2016
Saved almost $40 over the vet price no
By Margaret B.
Tucson, AZ
Revolution for dogs
April 22, 2016
Excellent product. Protects my dog from heartworm as well as fleas and ticks. Easy to administer. Entirely pets offers a great price and service.
ProsEffective against heartworm and fleas and ticks.
ConsNon
By Joan D.
Washington
Easy to apply, does the job
April 1, 2016
I have returned housing Revolution after trying other products, and applying this small amount of liquid on our dog's skin is working the best for her and for me. She didn't like the oral meds - spit them out after the first two treatments, and the other options were "too icky" when it came to cleaning her coat after application. She is a 47# Australian Shepherd.
By TD
California
Revolution
November 13, 2015
No problems on ordering, delivery, and great pricing!
By Christine
La Mesa, CA
What a deal!
October 23, 2015
Just like what I get from the vet, only better. Being a pet parent to 3 fur babies any time I can score a super great price on something I use what's not to like?!? I ran into some complications, on my end, but the people at Entirely Pets Pharmacy worked with me and I was able to get what I needed at the sale price! They were so helpful and understanding I can't see why I'd ever shop anywhere else. Thank you for a job well done.
ProsGreat service, great prices, friendly and caring people.

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