Revolution for dogs is a safe and simple, FDA-Approved, monthly topical medication used to protect your pet from heartworms, fleas, and ear mites. It also protects dogs from ticks and sarcoptic mange. Revolution requires a prescription from your veterinarian. (Example: 3 Pack=3 doses which lasts 3 months.)
Revolution is recommended for use in dogs six weeks of age or older.
Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations. Revolution also is indicated for the treatment and control of sarcoptic mange (Sarcoptes scabiei) and for the control of tick infestations due to Dermacentor variabilis.
Revolution works by penetrating the skin and entering your pet's bloodstream. Concentrations of selamectin, the active ingredient, in the tissue and bloodstream prevent heartworm disease. Selamectin also redistributes into the skin from the bloodstream and kills adult fleas, American dog ticks, and ear mites, and prevents flea eggs from hatching. It is also an anthelmintic, which means it fights to expel parasitic worms. Parasites ingest the drug when they feed on the animal's blood.
|Package Color||Selamactin Amount|
The recommended minimum dose is 2.7 mg selamectin per pound (6 mg/kg) of body weight.
|Dogs (lb)||Package Color||mg per tube||Potency (mg/ml)||Administered volume(mL)|
|Up to 5||Mauve||15 mg||60||0.25|
|For dogs over 130 lbs use the appropriate combination of tubes|
Revolution is flammable – Keep away from heat, sparks, open flames or other sources of ignition. Store below 30°C (86°F). After application, empty tubes can be placed in your normal household refuse for disposal.
Like all medicines, Revolution has some side effects. The most common is hair loss at the site of application with or without inflammation (redness, flaking) in cats. Other side effects reported in cats and dogs include vomiting, diarrhea with or without blood, anorexia (decreased appetite), lethargy (sluggishness), salivation, rapid breathing, pruritus (itching), urticaria (welts, hives), erythema (skin redness), ataxia (incoordination), fever and rare instances of death. There have also been rare reports of seizures in dogs.
If you have additional questions about possible side effects, talk to your veterinarian
Revolution is a prescription medication applied topically once a month. Do not use Revolution on puppies under 6 weeks of age or kittens under 8 weeks of age. According to the product literature, Revolution is safe for use on pregnant or lactating dogs and cats.
Revolution is a topical parasiticide applied once a month for the prevention of heartworm disease in dogs and cats. Revolution is also used on dogs for the treatment or prevention of fleas, the American Dog Tick, ear mites, and canine sarcoptic mange. When used on cats it is also used to treat or prevent fleas, ear mites, hookworms, and roundworms. It is recommended that heartworm prevention be used year-round. Revolution may also be used for purposes other than those listed in this guide.
Tell your veterinarian if your pet has ever had an allergic reaction to the medication.
Apply Revolution exactly as directed by your veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. Revolution is available as unit of use applicator tubes containing the specific amount of medication based on the weight of your pet. Revolution is available as a 15mg/0.25ml puppy/kitten dose for puppies older than 6 weeks and kittens older than 8 weeks weighing up to 5 lbs. Revolution is also available for cats 5.1-15 lbs (45mg/0.75ml), 15.1-22 lbs (60mg/1ml), and for dogs 5.1-10 lbs (30mg/0.25ml), dogs 10.1-20 lbs (60mg/0.5ml), 20.1-40 lbs (120mg/1 ml), 40-1-85 lbs (240mg/2 ml) and 85.1-130 lbs (360mg/3ml). For dogs over 130 lbs use the appropriate combination of tubes. The entire contents of the tube should be used. Do not split the contents as the accuracy of the dose and effectiveness of the medication cannot be assured. Bathing or shampooing your pet 2 or more hours after treatment will not reduce the effectiveness of Revolution. Keep this medication away from children and pets.
Give the missed dose as soon as you remember. Do not give a double dose of the medication.
Seek emergency veterinary medical treatment. Symptoms of overdose, while rare, may include salivation and lack of coordination, as well as symptoms listed below as side effects.
Because humans can contract hookworms from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the house and to not feed your pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended. Do not use on sick, weak, or underweight animals. Do not apply to wet hair. Dogs should be tested for heartworms prior to using Revolution. In humans, Revolution may be irritating to skin and eyes. Wash hands thoroughly after applying Revolution to your pet.
Side effects of Revolution that may occur include temporary hair loss at the site of application, loss of appetite, drooling, vomiting, diarrhea, drowsiness, rapid breathing, increased heart rate, and muscle tremors.
Do not apply Revolution to your pet if already giving an alternate heartworm medication. When switching from another heartworm medication, begin Revolution when the next dose of the heartworm medication is due.
Your pharmacist has additional information about Revolution written for health professionals that you may read.
I see fleas on my dog. Is Revolution working?
Revolution kills adult fleas and prevents flea eggs from hatching. You may occasionally see a few fleas on dogs or cats treated with Revolution but more than 98% of adult fleas are killed within 36 hours.
Immature stages of the flea called pupae may be present in your pets’ environment (yard, flooring, carpet, bedding, etc.). These pupae are not killed by parasiticides (including Revolution) and as such may emerge as adult fleas. These adult fleas may hop onto your pet at anytime. They must be exposed to Revolution on your dog or cat before being killed. It can take from 3–5 weeks (or longer depending on environmental conditions) for most fleas to complete their 4-stage life cycle (egg, larvae, pupae, and adult) and reach the adult stage before being seen on your pet. Due to the presence of immature flea stages in infested environments it can take up to 2 to 3 monthly applications for Revolution to maximally control the infestation of fleas in the environment. Once the flea population is controlled you will be less likely to see fleas.
Revolution controls tick infestations only due to the American Dog Tick (Dermacentor variabilis), a tick commonly found on dogs. There are other common species of ticks that are not killed or controlled by Revolution. Your veterinarian can recommend appropriate products to control or kill ticks common to your area. For the control of the American Dog Tick, Revolution should be applied once a month; however, your veterinarian may recommend a second administration applied 14 days after the first dose if your dog has a heavy tick infestation and/or recommend additional tick control methods. It may take up to 5 days to kill the majority of ticks on your dog.
In well-controlled clinical studies, Revolution was used safely in dogs and cats receiving other veterinary products such as vaccines, anthelmintics, antiparasitics, antibiotics, steroids, collars, shampoos and dips.
Tell your veterinarian about all medicines you have given your dog or cat in the past, and any medicines that you are planning to use with Revolution. This should include other medicines that you can get without a prescription. Your veterinarian may want to check that all of your dog’s or cat’s medicines can be given together.