What is compounding?
Drug compounding is often regarded as the process of combining or mixing drugs to create a medication tailored to the needs of an individual patient.
The generic form of Vetmedin is Pimobendan.
Vetmedin is in limited supply. Orders placed will be shipped as product continues to come off backorder.
Posatex Otic Suspension is an anti-bacterial, anti-inflammatory and anti-fungal medication for dogs that treats otitis externa associated with susceptible strains of yeast and bacteria.
Posatex Otic Suspension contains anti-bacterial, anti-inflammatory and anti-fungal properties to treat otitis externa, which is inflammation in the ear canal due to yeast and bacteria. Dogs with floppy ears tend to more susceptible to otitis externa since there is a limited amount of air-flow to the ear which creates a moist dark environment where bacteria and yeast thrive. Posatex Otic Suspension works by combining a broad spectrum antibiotic called Orbifloxacin, a potent anti-inflammatory agent called Mometasone Furoate Monohydrate and Novel triazole, a antifungal new to animal health.
Posatex Otic Suspension is indicated for the treatment of otitis externa in dogs associated with susceptible strains of yeast (Malassezia pachydermatis) and bacteria (coagulase positive staphylococci, Pseudomonas aeruginosa, and Enterococcus faecalis)
Posatex Otic Suspension is a registered trademark of Intervet Inc., d/b/a Merck Animal Health, a subsidiary of Merck & Co. Inc.
Shake well before use. For dogs weighing less than 30 lbs. instill 4 drops of Posatex Otic Suspension once daily into the ear canal. For dogs weighing 30 lbs. or more, instill 8 drops once daily into the ear canal. Therapy should continue for 7 consecutive days.
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Federal law prohibits the extralabel use of this drug in food-producing animals.
Posatex Otic Suspension is contraindicated in dogs with known or suspected hypersensitivity to quinolones, mometasone furoate monohydrate, or posaconazole. Do not use in dogs with known tympanic perforation (see Precautions).
Human Warnings: Not for use in humans. Keep out of reach of children.
Animal Warnings: Do not administer orally. Immediately discontinue use of Posatex Otic Suspension if hearing loss is observed during treatment (see Adverse Reactions).
The use of Posatex Otic Suspension in dogs with perforated tympanic membranes has not been evaluated. The integrity of the tympanic membranes should be confi rmed before administering this product.Avoid prolonged or repeated use of Posatex Otic Suspension. Long-term use of topical otic corticosteroids has been associated with adrenocortical suppressionand iatrogenic hyperadrenocorticism in dogs (see Animal Safety).
The safe use of Posatex Otic Suspension in dogs used for breeding purposes, during pregnancy or in lactating bitches, has not been evaluated. The systemic administration of quinolones has been shown to produce cartilage erosions of weight bearing joints and other signs of arthropathy in immature animals of various species.
In the field study, 143 dogs were treated with Posatex Otic Suspension. of those, 1 dog with bilateral otitis externa developed hearing loss. Posatex Otic Suspension treatment was discontinued and the condition resolved after one week.
To report suspected adverse reactions, call 1-800-224-5318.
For a copy of the Material Safety Data Sheet (MSDS) call 1-800-770-8878.
Posatex Otic Suspension was administered at 1,3, and 5 times the recommended dosage for 21 consecutive days. The control group received the vehicle in both ears at the clinical dose given five times per day. There was a slight decrease in serum cortisol concentration after ACTH stimulation on Day 21 in the 5X group. Erythema was noted in all groups. Aural pain, swelling, or heat were each noted in 3 separate dogs in the 5X group.
Store at temperatures between 2°-30°C (35.6°-86°F).Shake well before use.