Quellin (Carprofen) Soft Chewables | On Sale | EntirelyPets Rx
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Quellin (Carprofen) Soft Chewables

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  • Description
  • Ingredients
  • Directions
  • FAQ
  • Reviews

Description

Quellin is the first soft chewable formulation of carprofen (generic form of Rimadyl) which can make giving your pet's pain medication simple and easy. Each chewable is scored for effortless dosing and dogs love the meat flavor, so there's no need to hide the medication inside food or treats. Quellin requires a prescription from your veterinarian.

Key Benefits

  • Savory meat flavor and soft chewable tablet dogs take as a treat
  • Chewable tablet is scored for easy dosing
  • Can be given with or without food

How It Works

Quellin is a non-steroidal anti-inflammatory drug (NSAID) that relieves pain and inflammation from osteoarthritis or recent surgery to improve your dog's mobility. In most dogs, improvement can be seen in a few days.

Indications

Carprofen is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Specifications

  • Not for use in dogs exhibiting previous hypersensitivity to carprofen.
  • Soft chewable tablets are scored, and contain 25 mg, 75 mg, or 100 mg caprofen per tablet. Each tablet is packaged in bottles containing 30 or 120 soft chewable tablets.
  • Keep out of reach of children. Not for human use.
  • For use in dogs only. Do not use in cats. All dogs should undergo a thorough history and physical examination before initiation of NSAID therapy.
  • Consult a physician in cases of accidental ingestion by humans.
  • Manufacturer recommends appropriate laboratory tests to establish hematological and serum biochemical baseline data prior to, and periodically during, administration of any NSAID.

Prescription Required

Ingredients

Quellin Carprofen 25 mg Tablet
Active Ingredients (per tablet) Amount
Carprofen 25 mg
Quellin Carprofen 75 mg Tablet
Active Ingredients (per tablet) Amount
Carprofen 75 mg
Quellin Carprofen 100 mg Tablet
Active Ingredients (per tablet) Amount
Carprofen 100 mg

Directions

View Quellin Drug Facts Sheet.

Always provide Client Information Sheet with prescription. Carefully consider the potential benefits and risks of carprofen and other treatment options before deciding to use carprofen. Use the lowest effective dose for the shortest duration consistent with individual response. The recommended dose for oral administration to dogs is 2 mg/lb of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. quellin soft chewable tablets are scored and dosage should be calculated in half-tablet increments. Soft chewable tablets can be halved by holding the tablet on each side of the score line and pressing up in the middle to break the tablet into two pieces. Care should be taken to ensure that the dog consumes the complete dose.

Caution:

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Indications:

Carprofen is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.

Contraindications:

Carprofen should not be used in dogs exhibiting previous hypersensitivity to carprofen.

Warnings:

Keep out of reach of children. Not for human use. Consult a physician in cases of accidental ingestion by humans. For use in dogs only. Do not use in cats.

All dogs should undergo a thorough history and physical examination before initiation of NSAID therapy. Appropriate laboratory tests to establish hematological and serum biochemical baseline data prior to, and periodically during, administration of any NSAID should be considered. Owners should be advised to observe for signs of potential drug toxicity (see Information for Dog Owners, Adverse Reactions, Animal Safety and Post-Approval Experience).

Precautions:

As a class, cyclooxygenase inhibitory NSAIDs may be associated with gastrointestinal, renal and hepatic toxicity. Effects may result from decreased prostaglandin production and inhibition of the enzyme cyclooxygenase which is responsible for the formation of prostaglandins from arachidonic acid.11-14 When NSAIDs inhibit prostaglandins that cause inflammation they may also inhibit those prostaglandins which maintain normal homeostatic function. These anti-prostaglandin effects may result in clinically significant disease in patients with underlying or pre-existing disease more often than in healthy patients.12,14 NSAID therapy could unmask occult disease which has previously been undiagnosed due to the absence of apparent clinical signs. Patients with underlying renal disease for example, may experience exacerbation or decompensation of their renal disease while on NSAID therapy.11-14 The use of parenteral fluids during surgery should be considered to reduce the potential risk of renal complications when using NSAIDs perioperatively.

Carprofen is an NSAID, and as with others in that class, adverse reactions may occur with its use. The most frequently reported effects have been gastrointestinal signs. Events involving suspected renal, hematologic, neurologic, dermatologic and hepatic effects have also been reported. Patients at greatest risk for renal toxicity are those that are dehydrated, on concomitant diuretic therapy, or those with renal, cardiovascular, and/or hepatic dysfunction. Concurrent administration of potentially nephrotoxic drugs should be approached cautiously, with appropriate monitoring. Concomitant use of carprofen with other anti-inflammatory drugs, such as other NSAIDs or corticosteroids, should be avoided because of the potential increase of adverse reactions, including gastrointestinal ulcerations and/or perforations. Sensitivity to drug-associated adverse reactions varies with the individual patient. Dogs that have experienced adverse reactions from one NSAID may experience adverse reactions from another NSAID. Carprofen treatment was not associated with renal toxicity or gastrointestinal ulceration in well-controlled safety studies of up to ten times the dose in healthy dogs.

Carprofen is not recommended for use in dogs with bleeding disorders (e.g., Von Willebrand's disease), as safety has not been established in dogs with these disorders. The safe use of carprofen in animals less than 6 weeks of age, pregnant dogs, dogs used for breeding purposes, or in lactating bitches has not been established. Studies to determine the activity of carprofen when administered concomitantly with other protein-bound or similarly metabolized drugs have not been conducted. Drug compatibility should be monitored closely in patients requiring additional therapy. Such drugs commonly used include cardiac, anticonvulsant and behavioral medications. It has been suggested that treatment with carprofen may reduce the level of inhalant anesthetics needed.15 If additional pain medication is warranted after administration of the total daily dose of carprofen, alternative analgesia should be considered. The use of another NSAID is not recommended. Consider appropriate washout times when switching from one NSAID to another or when switching from corticosteroids use to NSAID use.

Information for Dog Owners:

Carprofen, like other drugs of its class, is not free from adverse reactions. Owners should be advised of the potential for dverse reactions and be informed of the clinical signs associated with drug intolerance. Adverse reactions may include decreased appetite, vomiting, diarrhea, dark or tarry stools, increased water consumption, increased urination, pale gums due to anemia, yellowing of gums, skin or white of the eye due to jaundice, lethargy, incoordination, seizure, or behavioral changes. Serious adverse reactions associated with this drug class can occur without warning and in rare situations result in death (see Adverse Reactions). Owners should be advised to discontinue quellin therapy and contact their veterinarian immediately if signs of intolerance are observed. The vast majority of patients with drug related adverse reactions have recovered when the signs are recognized, the drug is withdrawn, and veterinary care, if appropriate, is initiated. Owners should be advised of the importance of periodic follow up for all dogs during administration of any NSAID.

Animal Safety:

Laboratory studies in unanesthetized dogs and clinical field studies have demonstrated that carprofen is well tolerated in dogs after oral administration.

In target animal safety studies, carprofen was administered orally to healthy Beagle dogs at 1, 3 and 5 mg/lb twice daily (1, 3 and 5 times the recommended total daily dose) for 42 consecutive days with no significant adverse reactions. Serum albumin for a single female dog receiving 5 mg/lb twice daily decreased to 2.1 g/dL after 2 weeks of treatment, returned to the pre-treatment value(2.6 g/dL) after 4 weeks of treatment, and was 2.3 g/dL at the final 6-week evaluation. Over the 6-week treatment period, black or bloody stools were observed in 1 dog (1 incident) treated with 1 mg/lb twice daily and in 1 dog (2 incidents) treated with 3 mg/lb twice daily. Redness of the colonic mucosa was observed in 1 male that received 3 mg/lb twice daily.

Two of 8 dogs receiving 10 mg/lb orally twice daily (10 times the recommended total daily dose) for 14 days exhibited hypoalbuminemia. The mean albumin level in the dogs receiving this dose was lower (2.38 g/dL) than each of 2 placebo control groups (2.88 and 2.93 g/dL, respectively). Three incidents of black or bloody stool were observed in 1 dog. Five of 8 dogs exhibited reddened areas of duodenal mucosa on gross pathologic examination. Histologic exam of these areas revealed no evidence of ulceration, but did show minimal congestion of the lamina propria in 2 of the 5 dogs.

In separate safety studies lasting 13 and 52 weeks, respectively, dogs were administered orally up to 11.4 mg/lb/day (5.7 times the recommended total daily dose of 2 mg/lb) of carprofen. In both studies, the drug was well tolerated clinically by all of the animals. No gross or histologic changes were seen in any of the treated animals. In both studies, dogs receiving the highest doses had average increases inserum L-alanine aminotransferase (ALT) of approximately 20 IU.

In the 52-week study, minor dermatologic changes occurred in dogs in each of the treatment groups but not in the control dogs. The changes were described as slight redness or rash and were diagnosed as non-specific dermatitis. The possibility exists that these mild lesions were treatment related, but no dose relationship was observed.

Clinical field studies were conducted with 549 dogs of different breeds at the recommended oral doses for 14 days (297 dogs were included in a study evaluating 1 mg/lb twice daily and 252 dogs were included in a separate study evaluating 2 mg/lb once daily). In both studies the drug was clinically well tolerated and the incidence of clinical adverse reactions for carprofen-treated animals was no higher than placebo-treated animals (placebo contained inactive ingredients found in carprofen). For animals receiving 1 mg/lb twice daily, the mean post-treatment serum ALT values were 11 IU greater and 9 IU less than pre-treatment values for dogs receiving carprofen and placebo, respectively. Differences were not statistically significant. For animals receiving 2 mg/lb once daily, the mean post-treatment serum ALT values were 4.5 IU greater and 0.9 IU less than pre-treatment values for dogs receiving carprofen and placebo, respectively. In the latter study, 3 carprofen-treated dogs developed a 3-fold or greater increase in (ALT) and/or (AST) during the course of therapy. One placebo-treated dog had a greater than 2-fold increase in ALT. None of these animals showed clinical signs associated with laboratory value changes. Changes in the clinical laboratory values (hematology and clinical chemistry) were not considered clinically significant. The 1 mg/lb twice daily course of therapy was repeated as needed at 2-week intervals in 244 dogs, some for as long as 5 years.Clinical field studies were conducted in 297 dogs of different breeds undergoing orthopedic or soft tissue surgery. Dogs were administered 2 mg/lb of carprofen two hours prior to surgery then once daily, as needed for 2 days (soft tissue surgery) or 3 days (orthopedic surgery). Carprofen was well tolerated when used in conjunction with a variety of anesthetic-related drugs. The type and severity of abnormal health observation in carprofen- and placebo-treated animals were approximately equal and few in number (see Adverse Reactions). The most frequent abnormal health observation was vomiting and was observed at approximately the same frequency in carprofen- and placebo-treated animals. Changes in clinicopathologic indices of hematopoietic, renal, hepatic and clotting functions were not clinically significant. The mean post-treatment serum ALT values were 7.3 IU and 2.5 IU less than pre-treatment values for dogs receiving carprofen and placebo, respectively. The mean post-treatment AST values were 3.1 IU less for dogs receiving carprofen and 0.2 IU greater for dogs receiving placebo.

Effectiveness:

Confirmation of the effectiveness of quellin for the relief of pain and inflammation associated with osteoarthritis, and for the control of postoperative pain associated with soft tissue and orthopedic surgeries, was demonstrated in 5 placebo-controlled, masked studies examining the anti-inflammatory and analgesic effectiveness of carprofen in various breeds of dogs.

Separate placebo-controlled, masked, multicenter field studies confirmed the anti-inflammatory and analgesic effectiveness of carprofen caplets when dosed at2 mg/lb once daily or when divided and administered at 1 mg/lb twice daily. In these 2 field studies, dogs diagnosed with osteoarthritis showed statistically significant overall improvement based on lameness evaluations by the veterinarian and owner observations when administered carprofen at labeled doses.

Separate placebo-controlled, masked, multicenter field studies confirmed the effectiveness of carprofen caplets for the control of postoperative pain when dosed at 2 mg/lb once daily in various breeds of dogs. In these studies, dogs presented for ovariohysterectomy, cruciate repair and aural surgeries were administered carprofen preoperatively and for a maximum of 3 days (soft tissue) or 4 days (orthopedic) postoperatively. In general, dogs administered carprofen showed statistically significant reduction in pain scores compared to controls.

Storage:

Store at controlled room temperature 20°–25°C (68°–77°F).

FAQ

Quellin is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce pain and inflammation (soreness) due to osteoarthritis and pain following surgery in dogs. quellin is a prescription drug for dogs. It is available as a soft chewable tablet and is given to dogs by mouth. Osteoarthritis (OA) is a painful condition caused by “wear and tear” of cartilage and other parts of the joints that may result in the following changes or signs in your dog:

  • Limping or lameness
  • Decreased activity or exercise (reluctance to stand, climb stairs, jump or run, or difficulty in performing these activities)
  • Stiffness or decreased movement of jointsTo control surgical pain (e.g. for surgeries such as spays, ear procedures or orthopedic repairs) your veterinarian may administer quellin before the procedure and recommend that your dog be treated for several days after going home.

While quellin is not a cure for osteoarthritis, it can relieve the pain and inflammation of OA and improve your dog's mobility.

  • Response varies from dog to dog but can be quite dramatic.
  • In most dogs, improvement can be seen in a matter of days.
  • If quellin is discontinued or not given as directed, your dog's pain and inflammation may come back.

Your dog should not be given quellin if he/she:

  • Has had an allergic reaction to carprofen, the active ingredient of quellin.
  • Has had an allergic reaction to aspirin or other NSAIDs (for example deracoxib, etodolac, firocoxib, meloxicam, phenylbutazone or tepoxalin) such as hives, facial swelling, or red or itchy skin.

quellin should be given to dogs only. Cats should not be given quellin. Call your veterinarian immediately if your cat receives quellin. People should not take quellin. Keep quellin and all medicines out of reach of children. Call your physician immediately if you accidentally take quellin.

quellin should be given according to your veterinarian's instructions. Your veterinarian will tell you what amount of quellin is right for your dog and for how long it should be given. Most dogs will take quellin soft chewable tablets right out of your hand or the soft chewable tablet can be placed in the mouth. quellin may be given with or without food.

Talk to your veterinarian about:

  • The signs of OA you have observed (for example limping, stiffness).
  • The importance of weight control and exercise in the management of OA.
  • What tests might be done before quellin is prescribed.
  • How often your dog may need to be examined by your veterinarian.
  • The risks and benefits of using quellin.

Tell your veterinarian if your dog has ever had the following medical problems:

  • Experienced side effects from quellin or other NSAIDs, such as aspirin
  • Digestive upset (vomiting and/or diarrhea)
  • Liver disease
  • Kidney disease
  • A bleeding disorder (for example, Von Willebrand's disease)

Tell your veterinarian about:

  • Any other medical problems or allergies that your dog has now or has had.
  • All medicines that you are giving your dog or plan to give your dog, including those you can get without a prescription.

Tell your veterinarian if your dog is:

Pregnant, nursing or if you plan to breed your dog.

quellin, like other drugs, may cause some side effects. Serious but rare side effects have been reported in dogs taking NSAIDs, including quellin. Serious side effects can occur with or without warning and in rare situations result in death.

The most common NSAID-related side effects generally involve the stomach (such as bleeding ulcers), and liver or kidney problems. Look for the following side effects that can indicate your dog may be having a problem with quellin or may have another medical problem:

  • Decrease or increase in appetite
  • Vomiting
  • Change in bowel movements (such as diarrhea, or black, tarry or bloody stools)
  • Change in behavior (such as decreased or increased activity level, incoordination, seizure or aggression)
  • Yellowing of gums, skin, or whites of the eyes (jaundice)
  • Change in drinking habits (frequency, amount consumed)
  • Change in urination habits (frequency, color, or smell)
  • Change in skin (redness, scabs, or scratching)

It is important to stop therapy and contact your veterinarian immediately if you think your dog has a medical problem or side effect from quellin therapy. If you have additional questions about possible side effects, talk to your veterinarian.

quellin should not be given with other NSAIDs (for example, aspirin, deracoxib, etodolac, firocoxib, meloxicam, tepoxalin) or steroids (for example, cortisone, dexamethasone, prednisone, triamcinolone).

Tell your veterinarian about all medicines you have given your dog in the past, and any medicines that you are planning to give with quellin. This should include other medicines that you can get without a prescription. Your veterinarian may want to check that all of your dog's medicines can be given together.

Contact your veterinarian immediately if your dog eats more than the prescribed amount of quellin.
The soft chewable tablets are flavored. Keep quellin soft chewable tablets in a secured storage area out of the reach of your dog and other pets. If your dog ingests more than your veterinarian prescribed, or if your other pets take quellin soft chewable tablets, contact your veterinarian right away.

This sheet provides a summary of information about quellin. If you have any questions or concerns about quellin or osteoarthritis pain, or postoperative pain, talk to your veterinarian.

As with all prescribed medicines, quellin should only be given to the dog for which it was prescribed. It should be given to your dog only for the condition for which it was prescribed.

It is important to periodically discuss your dog's response to quellin at regular check ups. Your veterinarian will best determine if your dog is responding as expected and if your dog should continue receiving quellin.

Reviews

Review Summary
4.7
13 Reviews
5
69% (9)
4
31% (4)
3
0% (0)
2
0% (0)
1
0% (0)
100% Recommend this product (13 of 13 responses)
By Phill
Gilroy, CA
Beau Approves
July 12, 2020
Our boxer, Beau, tore his ACL (in dogs it’s called the CCL) and Quelling, from Entirely Pets, helps control inflammation.
By Timothy
Chelsea, MA
Good Rx POOR CUSTOMER SERVICE
January 23, 2020
I have a greyhound who is a retired racer. His leg was broken on the track and pinned. When I adopted him, an X-ray was taken which showed arthritis around the pinned area. The vet prescribed Carprofen 75mg twice a day. In the five years since he rescued me, I have tried various Carprofen products. I have found Quellin to work the best. The price was right and Entirely Pets Pharmacy has been great in contacting my vet for refills plus shipping this medication quickly. The reason for the 4 star is although it says "soft chewables", my greyhounds refuses to eat it by itself. It does hide better in his food than caplets, but I do not feed him 12 hours apart. I have to disguise it in a small amount of food.
By Alicia
PA.
Perfect.
October 18, 2019
I couldn't believe the price difference from my vet. I will be ordering again. My Golden needs 2 of these daily.
ProsPrice!!!!
By Auntie F.
Reno, NV
He loves them
October 16, 2018
My picky boy loves them. They’re soft so easy to divide if necessary and apparently tasty. He chews them up immediately. He usually at the Rimadyl chewable tablets but would sometimes spit them out.
ProsSoft, dividable, less expensive
ConsNo large bottles get several small bottles, take up more room in the cupboard. Bottles need to seal better, the last few get a little dry. Prefer non-childproof caps. No children in the house and the caps can be hard for the feeders with arthritis.
By Jill
Texas
Good Rx POOR CUSTOMER SERVICE
April 27, 2018
The Rx is fine but will never purchase from EntirelyPets Pharmacy again due to their extremely poor customer service.
By ColeenB
Philadelphia, Pennsylvania
Quelling works great for my greyhound
January 11, 2018
I have a greyhound who is a retired racer. His leg was broken on the track and pinned. When I adopted him, an X-ray was taken which showed arthritis around the pinned area. The vet prescribed Carprofen 75mg twice a day. In the five years since he rescued me, I have tried various Carprofen products. I have found Quellin to work the best. The price was right and Entirely Pets Pharmacy has been great in contacting my vet for refills plus shipping this medication quickly. The reason for the 4 star is although it says "soft chewables", my greyhounds refuses to eat it by itself. It does hide better in his food than caplets, but I do not feed him 12 hours apart. I have to disguise it in a small amount of food.
ProsWorks great
ConsGreyhound does like smell to chew without being hidden in food.
By kathy
Sellersville, PA
WONDERFUL GENERIC MEDICATION
November 6, 2017
My golden retriever has joint issues . I give her 1 per day to alleviate limping. It has been working very well and I will continue to purchase this product to avoid ACL surgery.
ProsSeems to alleviate limping Easy to give..chewable and she likes the taste..no need for pill pockets
Consnone so far
By Sue
Tucson, AZ
Love the product but...
May 5, 2017
Unfortunately the carprofen chewables expire in 6 months. I didn't know that and should have purchased way less as I only use 1/4 pill/day, so will have to use them after they expire or waste the extra.
ProsI have to cut the chewables into eighths which is impossible with the pill form. This makes it really easy and the dog likes them. I like working with Entirely Pets Pharmacy. This is my first prescription with them and they were great.
ConsThe expiration of the chewables really is a problem.
By Nanci
Mountain View, Ca.
great price
March 25, 2017
quick service and great prices
By Nanci
Mtn View, California
Great place to buy meds!
July 2, 2016
They are excellent! Process your order quickly, and it arrives so promptly, I'm amazed!
By Cindy
Oklahoma
This Medicine is Great!
November 20, 2015
My dog is 12 years ago. He was whining a lot and barely moving around. Limping. About a week after starting the medicine, we noticed that he seemed to feel better; now he's feeling a lot better. Moves around easily.
By Nanci S.
Mountain View, California
Quick and easy item to order
October 17, 2015
They got the RX from my vet, and promptly sent the order, great service!!
Proseasy order process quick and prompt delivery
By Olivia
Kerrville, Texas
Arthritis Pain Controlled
September 18, 2015
Our vet prescribed this medication for our 13 year old dog with arthritic back legs. He could barely walk to the end of our block and looked like he was in pain just getting up and down. Since he's been taking it a couple of months he's back to running up the stairs and walking up hill without hesitation. We've cut back the dosage like the vet suggested and he's still doing well. We didn't notice any side effects, either.

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