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Revolution for Cats

Revolution for Cats

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  • Description
  • Ingredients
  • Directions
  • FAQ
  • Reviews

Description

Revolution® (Selamectin) is a safe and simple monthly topical medication used to protect your dog or cat from heartworms, fleas, and ear mites. Revolution® (Selamectin) is also used on dogs for the treatment or prevention of fleas, the American Dog Tick, ear mites, and canine sarcoptic mange. When used on cats it is also used to treat or prevent fleas, ear mites, hookworms, and roundworms.

Key Benefits

  • Protects your pet from heartworms and fleas
  • Fights both internal and surface parasitic infections
  • Treats Sarcoptic mange in dogs
  • Treats and controls ear mites
  • Controls American Dog Tick infestation
  • Treats and controls roundworms and hookworms in cats
  • Only administered once a month
  • Safe and easy to use

Indication:

Revolution is recommended for use in dogs six weeks of age or older.

Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations. Revolution also is indicated for the treatment and control of sarcoptic mange (Sarcoptes scabiei) and for the control of tick infestations due to Dermacentor variabilis.

How It Works

Revolution works by penetrating the skin and entering your pet's bloodstream. Concentrations of selamectin, the active ingredient, in the tissue and bloodstream prevent heartworm disease. Selamectin also redistributes into the skin from the bloodstream and kills adult fleas, American dog ticks, and ear mites, and prevents flea eggs from hatching. It is also an anthelmintic, which means it fights to expel parasitic worms. Parasites ingest the drug when they feed on the animal's blood.

Ingredients

Revolution® (Selamectin) for Puppies/Kittens up to 5 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 15 mg
Revolution® (Selamectin) for Cats 5.1-15 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 45 mg
Revolution® (Selamectin) for Cats 15.1-22 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 60 mg
Revolution® (Selamectin) for Dogs 5.1-10 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 30 mg
Revolution® (Selamectin) for Dogs 10.1-20 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 60 mg
Revolution® (Selamectin) for Dogs 20.1-40 lbs:
Active Ingredients (per flavor tab) Amount
Milbemycin Oxime 120 mg
Revolution® (Selamectin) for Dogs 40.1-85 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 240 mg
Revolution® (Selamectin) for Dogs 85.1-130 lbs:
Active Ingredients (per flavor tab) Amount
Selamectin 360 mg

Directions

View Revolution product insert.

The recommended minimum dose is 2.7 mg selamectin per pound (6 mg/kg) of body weight. Administer the entire contents of a single dose tube (or two tubes used in combination for dogs weighing over 130 pounds) of Revolution topically in accordance with the following tables. (See Administration for the recommended treatment intervals.)

Dogs (lb) Package color mg per tube Potency (mg/mL) Administered volume (mL)
Up to 5 Mauve 15 mg 60 0.25
5.1-10 Purple 30 mg 120 0.25
10.1-20 Brown 60 mg 120 0.5
20.1-40 Red 120 mg 120 1.0
40.1-85 Teal 240 mg 120 2.0
85.1-130 Plum 360 mg 120 3.0

For dogs over 130 lbs use the appropriate combination of tubes.

Recommended for use in dogs 6 weeks of age and older and in cats 8 weeks of age and older.

Cats (lb) Package color mg per tube Potency (mg/mL) Administered volume (mL)
Up to 5 Mauve 15 mg 60 0.25
5.1-15 Blue 45 mg 60 0.75
15.1-22 Taupe 60 mg 60 1.0

For cats over 22 lbs use the appropriate combination of tubes.

Administration:

A veterinarian or veterinary technician should demonstrate or instruct the pet owner regarding the appropriatetechnique for applying Revolution topically to dogs and cats prior to first use. Firmly press the cap down to puncture the seal on the Revolution tube; a clicking sound will confirm that the cap has successfully punctured the seal. Remove the cap and check to ensure that the tip of the tube is open. To administer the product, part the hair on the back of the animal at the base of the neck in front of the shoulder blades until the skin is visible. Place the tip of the tube on the skin and squeeze the tube 3 or 4 times to empty its entire contents directly onto the skin in one spot. Keeping the tube squeezed, drag it away from the liquid and lift to remove. Check the tube to ensure that it is empty. Do not massage the product into the skin. Due to alcohol content, do not apply to broken skin. Avoid contact between the product and fingers. Do not apply when the haircoat is wet. Bathing or shampooing the dog 2 or more hours after treatment will not reduce the effectiveness of Revolution against fleas or heartworm. Bathing or shampooing the cat 2 hours after treatment will not reduce the effectiveness of Revolution against fleas. Bathing or shampooing the cat 24 hours after treatment will not reduce the effectiveness of Revolution against heartworm. Stiff hair, clumping of hair, hair discoloration, or a slight powdery residue may be observed at the treatment site in some animals. These effects are temporary and do not affect the safety or effectiveness of the product. Discard empty tubes in your ordinary household refuse.

Flea Control in Dogs and Cats

For the prevention and control of flea infestations, Revolution should be administered at monthly intervals throughout the flea season, starting one month before fleas become active. In controlled laboratory studies ›98% of fleas were killed within 36 hours. Results of clinical field studies using Revolution monthly demonstrated ›90% control of flea infestations within 30 days of the first dose. Dogs and cats treated with Revolution, including those with pre-existing flea allergy dermatitis, showed improvement in clinical signs associated with fleas as a direct result of eliminating the fleas from the animals and their environment.

If the dog or cat is already infested with fleas when the first dose of Revolution is administered, adult fleas on the animal are killed and no viable fleas hatch from eggs after the first administration. However, an environmental infestation of fleas may persist for a short time after beginning treatment with Revolution because of the emergence of adult fleas from pupae.

Heartworm Prevention in Dogs and Cats

For the prevention of heartworm disease, Revolution must be administered on a monthly basis. Revolution may be administered year-round or at least within one month after the animal's first exposure to mosquitoes and monthly thereafter until the end of the mosquito season. The final dose must be given within one month after the last exposure to mosquitoes. If a dose is missed and a monthly interval between dosing is exceeded then immediate administration of Revolution and resumption of monthly dosing will minimize the opportunity for the development of adult heartworms. When replacing another heartworm preventive product in a heartworm disease prevention program, the first dose of Revolution must be given within a month of the last dose of the former medication.

Selamectin, the active ingredient in Revolution, is a macrocyclic lactone compound. These compounds effectively prevent the development of adult heartworms when administered to dogs and cats within one month of exposure to infective (L3) Dirofilaria immitis larvae. Efficacy of macrocyclic lactones decreases below 100% in dogs, however, if first administered ›2 months after exposure to infective larvae. Thus, in heartworm endemic regions, delaying initiation of heartworm prevention using Revolution beyond 2 months of first exposure to infective larvae (e.g., starting puppies and kittens at ›8 weeks of age), or gaps of ›2 months in the administration of Revolution during periods of heartworm transmission, increases the risk of the animal acquiring heartworms. Animals with unknown heartworm history that test negative for heart-worms prior to the initiation of Revolution may be harboring pre-patent infections at the time Revolution was started. Testing such animals 3-4 months after initiation of Revolution would be necessary to confirm their negative heartworm status.

At the discretion of the veterinarian, cats ≥6 months of age may be tested to determine the presence of existing heartworm infections before beginning treatment with Revolution. Cats already infected with adult heartworms can be given Revolution monthly to prevent further infections.

Ear Mite Treatment in Dogs and Cats

For the treatment of ear mite (O. cynotis) infestations in dogs and cats, Revolution should be administered once as a single topical dose. A second monthly dose may be required in some dogs. Monthly use of Revolution will control any subsequent ear mite infestations. In the clinical field trials ears were not cleaned, and many animals still had debris in their ears after the second dose. Cleansing of the infested ears is recommended to remove the debris.

Sarcoptic Mange Treatment in Dogs

For the treatment of sarcoptic mange (S. scabiei) in dogs, Revolution should be administered once as a single topical dose. A second monthly dose may be required in some dogs. Monthly use of Revolution will control any subsequent sarcoptic mange mite infestations. Because of the difficulty in finding sarcoptic mange mites on skin scrapings, effectiveness assessments also were based on resolution of clinical signs. Resolution of the pruritus associated with the mite infestations was observed in approximately 50% of the dogs 30 days after the first treatment and in approximately 90% of the dogs 30 days after the second monthly treatment.

Tick Control in Dogs

For the control of tick (Dermacentor variabilis) infestations in dogs, Revolution should be administered on a monthly basis. In heavy tick infestations, complete efficacy may not be achieved after the first dose. In these cases, one additional dose may be administered two weeks after the previous dose, with monthly dosing continued thereafter.

Nematode Treatment in Cats

For the treatment and control of intestinal hookworm (A. tubaeforme) and roundworm (T. cati) infections, Revolution should be applied once as a single topical dose.

Safety:

Revolution has been tested safe in over 100 different pure and mixed breeds of healthy dogs and over 15 different pure and mixed breeds of healthy cats, including pregnant and lactating females, breeding males and females, puppies six weeks of age and older, kittens eight weeks of age and older, and avermectin sensitive collies. A kitten, estimated to be 5-6 weeks old (0.3 kg), died 8 ½ hours after receiving a single treatment of Revolution at the recommended dosage. The kitten displayed clinical signs which included muscle spasms, salivation and neurological signs. The kitten was a stray with an unknown history and was malnourished and underweight (see Warnings).

Dogs: In safety studies, Revolution was administered at 1, 3, 5, and 10 times the recommended dose to six-week-old puppies, and no adverse reactions were observed. The safety of Revolution administered orally also was tested in case of accidental oral ingestion. Oral administration of Revolution at the recommended topical dose in 5 to 8-month-old beagles did not cause any adverse reactions. In a pre-clinical study selamectin was dosed orally to ivermectin-sensitive collies. Oral administration of 2.5, 10, and 15 mg/kg in this dose escalating study did not cause any adverse reactions; however, eight hours after receiving 5 mg/kg orally, one avermectin-sensitive collie became ataxic for several hours, but did not show any other adverse reactions after receiving subsequent doses of 10 and 15 mg/kg orally. In a topical safety study conducted with avermectin-sensitive collies at 1, 3 and 5 times the recommended dose of Revolution, salivation was observed in all treatment groups, including the vehicle control. Revolution also was administered at 3 times the recommended dose to heartworm infected dogs, and no adverse effects were observed.

Cats: In safety studies, Revolution was applied at 1, 3, 5, and 10 times the recommended dose to six-week-old kittens. No adverse reactions were observed. The safety of Revolution administered orally also was tested in case of accidental oral ingestion. Oral administration of the recommended topical dose of Revolution to cats caused salivation and intermittent vomiting. Revolution also was applied at 4 times the recommended dose to patent heartworm infected cats, and no adverse reactions were observed. In well-controlled clinical studies, Revolution was used safely in animals receiving other frequently used veterinary products such as vaccines, anthelmintics, antiparasitics, antibiotics, steroids, collars, shampoos and dips.

FAQ

Revolution is a topical parasiticide that is applied to the skin of dogs six weeks of age and older and cats eight weeks of age and older to kill adult fleas and prevent flea eggs from hatching, prevent heartworm disease and protect your pet against other parasites (see below).

Dog Parasites:

  • Control and prevention of flea infestation (Ctenocephalides felis)
  • Prevention of heartworm disease (Dirofilaria immitis)
  • Treatment and control of ear mite infestation (Otodectes cynotis)
  • Treatment and control of sarcoptic mange (Sarcoptes scabiei)
  • Control of the American Dog Tick (Dermacentor variabilis)

Cat Parasites:

  • Control and prevention of flea infestation (Ctenocephalides felis)
  • Prevention of heartworm disease (Dirofilaria immitis)
  • Treatment and control of ear mite infestation (Otodectes cynotis)
  • Treatment and control of intestinal worms
    • Roundworm (Toxocara cati)
    • Hookworm (Ancylostoma tubaeforme)
Your veterinarian is best suited to discuss and recommend appropriate medications for your dog or cat. It is important to discuss your pet's health history with your veterinarian so he/she can decide if Revolution is right for your animal.

Dogs should be tested for heartworm disease prior to giving Revolution. If your dog tests positive for adult heartworms, your veterinarian can recommend appropriate treatment. Dogs infected with adult heartworms can safely be given Revolution.

If your cat is older than six months of age, your veterinarian may decide to test him/her for heartworm disease before prescribing Revolution. Cats infected with adult heartworms can be given Revolution to prevent further infections.

Your veterinarian will recommend the appropriate dose for your dog or cat based on your animal's body weight. You should not administer Revolution to dogs younger than 6 weeks of age or cats younger than 8 weeks of age. Revolution is available in eight separate dose strengths for dogs and cats of different weights.
If you forget to apply a monthly dose of Revolution, immediately apply Revolution, resume monthly applications, and notify your veterinarian.
Contact your veterinarian if you administer more than the prescribed amount of Revolution.

  1. Remove the Revolution tube from its protective package.
  2. Holding the tube upright, firmly press the cap down until you hear a 'click' sound, which signals that the cap has punctured the applicator seal. Remove the cap and check to be sure that the tip of the tube is open.
  3. Part the hair on the back of the animal at the base of the neck, in front of the shoulder blades, until the skin is visible.
  4. Apply the tip of the Revolution tube directly to the skin. Squeeze the tube firmly 3-4 times in one spot until empty. Keep tube compressed on the final squeeze to avoid drawing liquid back into tube. Avoid contact between Revolution and your fingers.
  5. While keeping tube squeezed, drag it away from liquid and lift up to remove.
  6. Ensure tube is empty.

Do not massage Revolution into the skin.

Do not apply when the haircoat is wet.

Do not apply to broken skin Revolution contains alcohol.

Stiff hair, clumping of hair, hair discoloration, or a slight powdery residue may be observed at the site in some animals. These effects are usually temporary and do not affect the safety or effectiveness of the product.

Yes. Bathing or shampooing the dog 2 or more hours after treatment will not reduce the effectiveness of Revolution against fleas or heartworm. Bathing or shampooing the cat 2 hours after treatment will not reduce the effectiveness of Revolution against fleas. Bathing or shampooing the cat 24 hours after treatment will not reduce the effectiveness of Revolution against heartworm.
You should avoid contact with application site when wet. You may hold or play with your pet any time after the area on which Revolution was applied is dry.

Revolution kills adult fleas and prevents flea eggs from hatching. You may occasionally see a few fleas on dogs or cats treated with Revolution but more than 98% of adult fleas are killed within 36 hours.

RImmature stages of the flea called pupae may be present in your pets' environment (yard, flooring, carpet, bedding, etc.). These pupae are not killed by parasiticides (including Revolution) and as such may emerge as adult fleas. These adult fleas may hop onto your pet at anytime. They must be exposed to Revolution on your dog or cat before being killed. It can take from 3-5 weeks (or longer depending on environmental conditions) for most fleas to complete their 4-stage life cycle (egg, larvae, pupae, and adult) and reach the adult stage before being seen on your pet. Due to the presence of immature flea stages in infested environments it can take up to 2 to 3 monthly applications for Revolution to maximally control the infestation of fleas in the environment. Once the flea population is controlled you will be less likely to see fleas.

Revolution controls tick infestations only due to the American Dog Tick (Dermacentor variabilis), a tick commonly found on dogs. There are other common species of ticks that are not killed or controlled by Revolution. Your veterinarian can recommend appropriate products to control or kill ticks common to your area. For the control of the American Dog Tick, Revolution should be applied once a month; however, your veterinarian may recommend a second administration applied 14 days after the first dose if your dog has a heavy tick infestation and/or recommend additional tick control methods. It may take up to 5 days to kill the majority of ticks on your dog.

Like all medicines, Revolution has some side effects. The most common is hair loss at the site of application with or without inflammation (redness, flaking) in cats. Other side effects reported in cats and dogs include vomiting, diarrhea with or without blood, anorexia (decreased appetite), lethargy (sluggishness), salivation, rapid breathing, pruritus (itching), urticaria (welts, hives), erythema (skin redness), ataxia (incoordination), fever and rare instances of death. There have also been rare reports of seizures in dogs.

If you have additional questions about possible side effects, talk to your veterinarian.

In well-controlled clinical studies, Revolution was used safely in dogs and cats receiving other veterinary products such as vaccines, anthelmintics, antiparasitics, antibiotics, steroids, collars, shampoos and dips.Tell your veterinarian about all medicines you have given your dog or cat in the past, and any medicines that you are planning to use with Revolution. This should include other medicines that you can get without a prescription. Your veterinarian may want to check that all of your dog's or cat's medicines can be given together.
Revolution is not for use in humans. Revolution should be kept out of reach of children. In humans, Revolution may be irritating to skin and eyes. Reactions such as hives, itching and skin redness have been reported in humans in rare instances. Individuals with known hypersensitivity to Revolution should use the product with caution or consult a health care professional. Revolution contains isopropyl alcohol and the preservative butylated hydroxytoluene (BHT). Wash hands after use and wash off any product in contact with the skin immediately with soap and water. In case of human ingestion contact a doctor immediately.

Reviews

Review Summary
4.9
17 Reviews
5
94% (16)
4
0% (0)
3
6% (1)
2
0% (0)
1
0% (0)
100% Recommend this product (17 of 17 responses)
By Peaches
Stockton, CA
One Product Does It All
September 11, 2020
We have three rescue cats and have used the Revolution Product line for the last seven years. The product is easy to apply and it appears to last the entire month. We are very happy to give a 5-Star review.
By Cindy E.
Santa Maria California 93454
excellent product
November 19, 2019
This is an excellent product. I applied 1 dose to each of our 2 adult cats. 8lbs and 5lbs and also a drop on each of 6 kittens. The fleas are under control and we're thrilled.....great product.
Merchant Response:It's good to be flea-free! Take care Cindy!
ProsA mother cat and her 5 month old kitten received a one month dose each. and her 6 8 week old kittens each got a drop each....and the results are wonderful....Good stuff!!!
By Mary J.
Santa Rosa, CA
Great Service! Thanks to Everyone Who Helped. This Is/Was My 1st Time To Shop With You!
November 13, 2019
ll: My Friend Diane introduced me to your "Entirely Pets Pharmacy" and helped me get started buying my 6 doses of Revolution for my Kitty!

I appreciate your fast, excellent service and look forward to doing business with you in the future.

I will also tell other friends about your Superb Service!!! :ll
Merchant Response:Hi Mary, I would like to personally thank you for ordering with EntirelyPets Pharmacy. We appreciate your business and the opportunity to service you. We are so glad to hear that we were able to help your Kitty.
By Amanda
OH
Great price
November 17, 2018
Very happy that one dose is available for purchase! Order was fulfilled quickly.
By Onosmom
NorCal
Cats Monthly Meds
October 27, 2018
Great! Good price and they contact my vet for the RX. Easy procedure. Thanks!
By Likestoshop
SW CO
This Really Works
September 5, 2018
I like this product and find that it is effective and without side effects for my cat.
By Amanda
OH
Good product but terrible service
May 5, 2018
This was my first order from Entirely Pets, but not my first purchase of Revolution. The price was great, but it took about 10 days or longer to receive my order. I ordered a week or more in advance of when I would need the next dose, but it did not arrive in time. I had to borrow a dose from a family member who uses the exact same product. The 3 doses did not come packaged in a sealed box from the manufacturer, as they have with every other online stores. There was no packaging at all, just 3 does in an envelope.
Merchant Response:We have since perfected our prescription approval process. Our turn around time is under 3 days. Glad to have you and your cat as customers!
Consservice, packaging
By Angelkitty
Florida
Really keep the fleas off
March 5, 2018
Revolution brand flea and tick treatment is the only brand that has worked, and I have been treating cats with it for over 20 years now. It is well worth the cost of testing the cat for heart worms prior to using this product.
ProsKeeps all the fleas off, never have to think about a flea problem when the cat is treated once a month with Revolution
ConsI had a little problem with ticks on one of our cats that likes to roam and hunt this winter. I did pull them off after locating them around her neck area, but this left sores that took weeks to actually heal and cover over with fur again. Our home sets on 3 actress and is next to a wooded lot, with a lot of sand pine trees. I know pine trees are notorious for breading ticks, soo I am hopefull that in the future the Revolution will work better.
By Java
Truro, MA
Works well for the price
November 18, 2016
My Vet originally told me about revolution so My cat gets his monthly dose with no problems.
ProsOK for my needs
By Janet
Brookport, IL and El Segundo, CA
REVOLUTION WORKS GREAT, PRINCESS IS HAPPY
November 11, 2016
We have a large short-hair all white cat named Princess with the thickest fur I have ever, ever seen on a cat. She is not allowed outside. The other flea medication we used stopped working and she got fleas. She was miserable, as were we. Revolution for Cats works great on Princess as she weighs 19 lbs. This is no thanks to Entirely Pets Pharmacy. Do not trust Entirely Pets Pharmacy to ship right away. They do not! By the time they finally shipped the prescription, we had left Illinois for California. So, I had to go to the expense of shipping it back to Illinois the the lady who was caring for Princess in our absence. I had to ship it Fedex Overnight as she was 3 days past due on this medication for fleas, ticks, ear mites, etc. This is the SECOND time this has happened, so Entirely Pets Pharmacy cannot say it just "fell through the cracks" as I'm sure they will claim. Dreadful service, and I have emails to them to prove it. No one at Entirely Pets Pharmacy, apparently, reads emails although the encourage customers to communicate with them!
ProsRevolution for large cats work just great.
ConsEntirely Pets Pharmacy cannot be trusted to ship right away -- even if they have the prescription already! As a customer, I don't know if it is the fault of the person filling the prescription, or the shipping department. And no one actually reads emails they receive.
By Grandma
Chicagoland
Cat Safety
July 22, 2016
My cats have been pest and parasite free using Revolution for several years! We travel all over the country and they would be continuously exposed to many different kinds.
By Megan
Connecticut
Good prevention
April 27, 2016
This is supposed to be the best prevention out there right now. I've been using it a little over a year for my cat, and he has not had a problem.
By Karen
Long Beach Ca.
Irradicate fleas from your Life!
September 27, 2015
This Product is the best on the market, since using it our home, animals and front and back Yard are Flea free! Even in this hot weather and even skipped months of treatment in winter. Because no fleas. But it also keeps the heart worms and ticks away too!
Also it disappates quickly after applying and the animals recover from the fear of being treated easily. Highly recommend this and worth every penny, but I wish it were less expensive. Thanks for the prompt service and delivery.
ProsFast order and delivery excellent product.
ConsNo complaints other than the price of Revolution being high, but product is great and your price too!
By Janice
Marietta, GA
Entirely Purrfect!
September 27, 2015
Ordering from Entirely Pets is seamless! They contacted my veterinarian for the required prescription, delivered the product to my door, AND I saved money. My kitty cats say "meow" (thank you) and so do I.
By Tim
Weatherford, TX
Great Product, delivered timely
August 30, 2015
EntirelyPets does a superb job delivering a fantastic product! Thank you for your quick delivery!
By A
Grayson County, TX
Love this product and this company
July 31, 2015
product came in fast and excellent customer service
Constoo expensive
By LSR
Texas
Best protection
July 9, 2015
All cats need heart worn protection just like dogs! Easy to use.

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