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Revolution for Cats

Revolution for Cats

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  • Description
  • Ingredients
  • Directions
  • FAQ
  • Reviews


Revolution for cats is a safe and simple, FDA-Approved, monthly topical medication used to protect your pet from heartworms, fleas, and ear mites. It also protects cats from roundworms and hookworms. Revolution requires a prescription from your veterinarian. (Example: 3 Pack = 3 doses which lasts 3 months.)

Key Benefits

  • Protects your pet from heartworms, fleas, and ear mites, among other foreign invaders
  • Fights both internal and surface parasitic infections
  • Treats mange
  • Only administered once a month
  • Safe and easy to use

How It Works

Revolution works by penetrating the skin and entering your pet's bloodstream. Concentrations of selamectin, the active ingredient, in the tissue and bloodstream prevent heartworm disease. Selamectin also redistributes into the skin from the bloodstream and kills adult fleas, American dog ticks, and ear mites, and prevents flea eggs from hatching. It is also an anthelmintic, which means it fights to expel parasitic worms. Parasites ingest the drug when they feed on the animal's blood.

Prescription Required

NADA 141-152

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Active Ingredient


Package ColorSelamactin Amount
Mauve15 mg
Blue45 mg
Taupe60 mg


View Revolution product insert.


The recommended minimum dose is 2.7 mg selamectin per pound (6 mg/kg) of body weight.

Dosage Table

Cats (lb) Package Color mg per tube Potency (mg/mL Administered volume (mL)
Up to 5Mauve15 mg600.25
5.1-15Blue45 mg600.75
15.1-22Taupe60 mg601.0

For cats over 22 lbs use the appropriate combination of tubes.


  1. Remove the Revolution tube from its protective package.
  2. Holding the tube upright, firmly press the cap down until you hear a ‘click’ sound, which signals that the cap has punctured the applicator seal. Remove the cap and check to be sure that the tip of the tube is open.
  3. Part the hair on the back of the animal at the base of the neck, in front of the shoulder blades, until the skin is visible.
  4. Apply the tip of the Revolution tube directly to the skin. Squeeze the tube firmly 3–4 times in one spot until empty. Keep tube compressed on the final squeeze to avoid drawing liquid back into tube. Avoid contact between Revolution and your fingers.
  5. While keeping tube squeezed, drag it away from liquid and lift up to remove.
  6. Ensure tube is empty.

Quick Tips

  • Do not massage Revolution into the skin.
  • Do not apply when the haircoat is wet.
  • Do not apply to broken skin – Revolution contains alcohol.

Storage Directions

Revolution is flammable – Keep away from heat, sparks, open flames or other sources of ignition. Store below 30°C (86°F). After application, empty tubes can be placed in your normal household refuse for disposal.

Possible Side Effects

Like all medicines, Revolution has some side effects. The most common is hair loss at the site of application with or without inflammation (redness, flaking) in cats. Other side effects reported in cats and dogs include vomiting, diarrhea with or without blood, anorexia (decreased appetite), lethargy (sluggishness), salivation, rapid breathing, pruritus (itching), urticaria (welts, hives), erythema (skin redness), ataxia (incoordination), fever and rare instances of death. There have also been rare reports of seizures in dogs.

If you have additional questions about possible side effects, talk to your veterinarian


What is the most important information I should know about Revolution?

Revolution is a prescription medication applied topically once a month. Do not use Revolution on puppies under 6 weeks of age or kittens under 8 weeks of age. According to the product literature, Revolution is safe for use on pregnant or lactating dogs and cats.

What is Revolution?

Revolution is a topical parasiticide applied once a month for the prevention of heartworm disease in dogs and cats. Revolution is also used on dogs for the treatment or prevention of fleas, the American Dog Tick, ear mites, and canine sarcoptic mange. When used on cats it is also used to treat or prevent fleas, ear mites, hookworms, and roundworms. It is recommended that heartworm prevention be used year-round. Revolution may also be used for purposes other than those listed in this guide.

What should I discuss with my veterinarian before applying Revolution on my pet?

Tell your veterinarian if your pet has ever had an allergic reaction to the medication.

How should this medication be used?

Apply Revolution exactly as directed by your veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. Revolution is available as unit of use applicator tubes containing the specific amount of medication based on the weight of your pet. Revolution is available as a 15mg/0.25ml puppy/kitten dose for puppies older than 6 weeks and kittens older than 8 weeks weighing up to 5 lbs. Revolution is also available for cats 5.1-15 lbs (45mg/0.75ml), 15.1-22 lbs (60mg/1ml), and for dogs 5.1-10 lbs (30mg/0.25ml), dogs 10.1-20 lbs (60mg/0.5ml), 20.1-40 lbs (120mg/1 ml), 40-1-85 lbs (240mg/2 ml) and 85.1-130 lbs (360mg/3ml). For dogs over 130 lbs use the appropriate combination of tubes. The entire contents of the tube should be used. Do not split the contents as the accuracy of the dose and effectiveness of the medication cannot be assured. Bathing or shampooing your pet 2 or more hours after treatment will not reduce the effectiveness of Revolution. Keep this medication away from children and pets.

What happens if I miss applying a dose?

Give the missed dose as soon as you remember. Do not give a double dose of the medication.

What happens if I overdose the pet?

Seek emergency veterinary medical treatment. Symptoms of overdose, while rare, may include salivation and lack of coordination, as well as symptoms listed below as side effects.

What should I avoid while using Revolution on my pet?

Because humans can contract hookworms from animals, it is important to maintain good personal hygiene. It is also important to eliminate fleas on your pet and in the househand to not feed your pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended. Do not use on sick, weak, or underweight animals. Do not apply to wet hair. Dogs should be tested for heartworms prior to using Revolution. In humans, Revolution may be irritating to skin and eyes. Wash hands thoroughly after applying Revolution to your pet.

What are the possible side effects of Revolution?

Side effects of Revolution that may occur include temporary hair loss at the site of application, loss of appetite, drooling, vomiting, diarrhea, drowsiness, rapid breathing, increased heart rate, and muscle tremors.

What other drugs will affect Revolution?

Do not apply Revolution to your pet if already giving an alternate heartworm medication. When switching from another heartworm medication, begin Revolution when the next dose of the heartworm medication is due.

Where can I get more information?

Your pharmacist has additional information about Revolution written for health professionals that you may read.


Review Summary
16 Reviews
94% (15)
0% (0)
6% (1)
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0% (0)
100% Recommend this product (16 of 16 responses)
By Cindy E.
Santa Maria California 93454
excellent product
November 19, 2019
This is an excellent product. I applied 1 dose to each of our 2 adult cats. 8lbs and 5lbs and also a drop on each of 6 kittens. The fleas are under control and we're thrilled.....great product.
Merchant Response:It's good to be flea-free! Take care Cindy!
ProsA mother cat and her 5 month old kitten received a one month dose each. and her 6 8 week old kittens each got a drop each....and the results are wonderful....Good stuff!!!
By Mary J.
Santa Rosa, CA
Great Service! Thanks to Everyone Who Helped. This Is/Was My 1st Time To Shop With You!
November 13, 2019
ll: My Friend Diane introduced me to your "Entirely Pets Pharmacy" and helped me get started buying my 6 doses of Revolution for my Kitty!

I appreciate your fast, excellent service and look forward to doing business with you in the future.

I will also tell other friends about your Superb Service!!! :ll
Merchant Response:Hi Mary, I would like to personally thank you for ordering with EntirelyPets Pharmacy. We appreciate your business and the opportunity to service you. We are so glad to hear that we were able to help your Kitty.
By Amanda
Great price
November 17, 2018
Very happy that one dose is available for purchase! Order was fulfilled quickly.
By Onosmom
Cats Monthly Meds
October 27, 2018
Great! Good price and they contact my vet for the RX. Easy procedure. Thanks!
By Likestoshop
This Really Works
September 5, 2018
I like this product and find that it is effective and without side effects for my cat.
By Amanda
Good product but terrible service
May 5, 2018
This was my first order from Entirely Pets, but not my first purchase of Revolution. The price was great, but it took about 10 days or longer to receive my order. I ordered a week or more in advance of when I would need the next dose, but it did not arrive in time. I had to borrow a dose from a family member who uses the exact same product. The 3 doses did not come packaged in a sealed box from the manufacturer, as they have with every other online stores. There was no packaging at all, just 3 does in an envelope.
Merchant Response:We have since perfected our prescription approval process. Our turn around time is under 3 days. Glad to have you and your cat as customers!
Consservice, packaging
By Angelkitty
Really keep the fleas off
March 5, 2018
Revolution brand flea and tick treatment is the only brand that has worked, and I have been treating cats with it for over 20 years now. It is well worth the cost of testing the cat for heart worms prior to using this product.
ProsKeeps all the fleas off, never have to think about a flea problem when the cat is treated once a month with Revolution
ConsI had a little problem with ticks on one of our cats that likes to roam and hunt this winter. I did pull them off after locating them around her neck area, but this left sores that took weeks to actually heal and cover over with fur again. Our home sets on 3 actress and is next to a wooded lot, with a lot of sand pine trees. I know pine trees are notorious for breading ticks, soo I am hopefull that in the future the Revolution will work better.
By Java
Truro, MA
Works well for the price
November 18, 2016
My Vet originally told me about revolution so My cat gets his monthly dose with no problems.
ProsOK for my needs
By Janet
Brookport, IL and El Segundo, CA
November 11, 2016
We have a large short-hair all white cat named Princess with the thickest fur I have ever, ever seen on a cat. She is not allowed outside. The other flea medication we used stopped working and she got fleas. She was miserable, as were we. Revolution for Cats works great on Princess as she weighs 19 lbs. This is no thanks to Entirely Pets Pharmacy. Do not trust Entirely Pets Pharmacy to ship right away. They do not! By the time they finally shipped the prescription, we had left Illinois for California. So, I had to go to the expense of shipping it back to Illinois the the lady who was caring for Princess in our absence. I had to ship it Fedex Overnight as she was 3 days past due on this medication for fleas, ticks, ear mites, etc. This is the SECOND time this has happened, so Entirely Pets Pharmacy cannot say it just "fell through the cracks" as I'm sure they will claim. Dreadful service, and I have emails to them to prove it. No one at Entirely Pets Pharmacy, apparently, reads emails although the encourage customers to communicate with them!
ProsRevolution for large cats work just great.
ConsEntirely Pets Pharmacy cannot be trusted to ship right away -- even if they have the prescription already! As a customer, I don't know if it is the fault of the person filling the prescription, or the shipping department. And no one actually reads emails they receive.
By Grandma
Cat Safety
July 22, 2016
My cats have been pest and parasite free using Revolution for several years! We travel all over the country and they would be continuously exposed to many different kinds.
By Megan
Good prevention
April 27, 2016
This is supposed to be the best prevention out there right now. I've been using it a little over a year for my cat, and he has not had a problem.
By Karen
Long Beach Ca.
Irradicate fleas from your Life!
September 27, 2015
This Product is the best on the market, since using it our home, animals and front and back Yard are Flea free! Even in this hot weather and even skipped months of treatment in winter. Because no fleas. But it also keeps the heart worms and ticks away too!
Also it disappates quickly after applying and the animals recover from the fear of being treated easily. Highly recommend this and worth every penny, but I wish it were less expensive. Thanks for the prompt service and delivery.
ProsFast order and delivery excellent product.
ConsNo complaints other than the price of Revolution being high, but product is great and your price too!
By Janice
Marietta, GA
Entirely Purrfect!
September 27, 2015
Ordering from Entirely Pets is seamless! They contacted my veterinarian for the required prescription, delivered the product to my door, AND I saved money. My kitty cats say "meow" (thank you) and so do I.
By Tim
Weatherford, TX
Great Product, delivered timely
August 30, 2015
EntirelyPets does a superb job delivering a fantastic product! Thank you for your quick delivery!
By A
Grayson County, TX
Love this product and this company
July 31, 2015
product came in fast and excellent customer service
Constoo expensive
Best protection
July 9, 2015
All cats need heart worn protection just like dogs! Easy to use.

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