Atopica is an oral solution prescribed to dogs who suffer from allergic dermatitis—a skin reaction caused by contact with an allergen. This is very common in canines with allergies, and can cause their skin to become uncomfortably itchy, red and scaly. Atopica targets the root of the problem to help relieve itching, so your companion no longer feels the need to incessantly scratch, rub or lick. Atopica can help provide your dog the relief she needs.
For: Dogs (at least 6 months of age and weighing at least 4 pounds)
How it works: Atopica targets the immune cells involved in the allergic reaction. You usually only administer one dose a day to control symptoms, but many dogs can be effectively controlled with every-other-day or twice-weekly dosing.
The initial dose of Atopica is 5 mg/kg/day (3.3-6.7 mg/kg/day) as a single daily dose for 30 days. Following this initial daily treatment period, the dose of Atopica may be tapered by decreasing the frequency of dosing to every other day or twice weekly, until a minimum frequency is reached which will maintain the desired therapeutic effect. Atopica should be given at least one hour before or two hours after a meal. If a dose is missed, the next dose should be administered (without doubling) as soon as possible, but dosing should be no more frequent than once daily.
|Dog Body weight (lbs)||Dog Body weight (kg)||Dose 5 mg/kg|
|4-6.5 lbs||2-2.9 kg||10 mg capsule|
|6.6-9 lbs||3-3.9 kg||2 x 10 mg capsule|
|9.1-16 lbs||4-7.9 kg||25 mg capsule|
|16.1-33 lbs||8-14.9 kg||50 mg capsule|
|33.1-64 lbs||15-28.9 kg||100 mg capsule|
|64.1-79 lbs||29-35.9 kg||100 mg capsule + 50 mg capsules|
|79.1-121 lbs||36-55.9 kg||2 x 100 mg capsules|
Contraindications: ATOPICA is contraindicated for use in dogs with a history of neoplasia. Do not use in dogs with a hypersensitivity to cyclosporine.
Warnings: ATOPICA (cyclosporine) is a systemic immunosuppressant that may increase the susceptibility to infection and the development of neoplasia.
Human Warnings: Not for human use. Keep this and all drugs out of reach of children.
For use only in dogs.
Capsules should not be broken or opened. Wear gloves during administration. Wash hands after administration. In case of accidental ingestion, seek medical advice immediately and provide the package insert or the label to the physician.
Cautions: There are many possible drug interactions. Be sure to tell your veterinarian what other medications your pet is currently using. Give Atopica at least one hour before food or 2 hours after food.
What happens if I miss giving a dose: Give the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and give the next regularly scheduled dose. Do not give a double dose unless otherwise directed by your veterinarian.
What happens if I overdose the pet: Seek emergency veterinary medical treatment.
Possible side effects of Atopica: If any of the following serious side effects occur, stop giving Atopica and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing, swelling of the lips, tongue or face, and hives). Other less serious side effects may occur. Continue giving Atopica and talk to your veterinarian if your pet develops vomiting, soft stools or diarrhea, muscle cramps, muscle weakness, loss of appetite, and change of hair coat. Other side effects may occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.
What should I avoid while giving Atopica to my pet: The safe use in breeding, pregnant or lactating pets has not been determined. Do not use Atopica in pets with known allergy to the medication. The drug should not be used in pets with kidney disease, stomach ulcers, and certain blood disorders. Prolonged use of Atopica can result in bacterial or fungal infection related to a decreased effect of the immune system.
What other drugs will affect Atopica: Tell your veterinarian what medications your pet is currently using and any new products, including herbal remedies you may start to give. Drug/drug interactions could cause a decrease in effectiveness or an increase in side effects of either Atopica or the other medication being given. Examples of medications that may cause drug/drug interactions are; SMZ-TMP (Bactrim, Septra), gentamicin, etodolac (EtoGesic), piroxicam (Feldene), ketoconazole (Nizoral), cimetidine (Tagamet), ranitidine (Zantac), itraconoazole (Sporanox), methylprednisolone (Medrol), erythromycin, Allopurinol (Zyloprim), metoclopramide (Reglan), prednisOLOne, digoxin (Lanoxin), any type of vaccination.
What should I discuss with my veterinarian before giving Atopica: Tell your veterinarian if your pet has liver disease, kidney disease, cancer, high blood pressure, a viral, bacterial or fungal infection, or any other serious or chronic condition. Tell your veterinarian if your pet is pregnant or lactating, and if you plan to breed your pet.
What is the most important information I should know about Atopica: Notify your veterinarian immediately if your pet develops fever (over 103°), painful urination, tiredness, sneezing, coughing, or runny nose.These symptoms could be early signs of dangerous side effects.