RIMADYL (Carprofen) by Pfizer is a 24-hour, non-steroidal anti-inflammatory drug (NSAID) designed to treat arthritis in dogs. Rimadyl (Carprofen) are used for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs. Dogs love these liver-flavored Rimadyl (Carprofen) tablets. Although effective for most dogs, Rimadyl (Carprofen) should not be used in any dog with kidney, liver, or heart disease. Do not give to dogs that are pregnant or nursing.
INDICATIONS: Rimadyl is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
DOSAGE AND ADMINISTRATION: Always provide Client Information Sheet with prescription. Carefully consider the potential benefits and risk of Rimadyl and other treatment options before deciding to use Rimadyl. Use the lowest effective dose for the shortest duration consistent with individual response. The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Rimadyl tablets are scored, and dosage should be calculated in half-tablet increments. Tablets can be halved by placing the tablet on a hard surface and pressing down on both sides of the score. Rimadyl chewable tablets are palatable and willingly consumed by most dogs when offered by the owner. Therefore, they may be fed by hand or placed on food. Care should be taken to ensure that the dog consumes the complete dose.
The recommended dosage for subcutaneous administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as either 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For control of post-operative pain, administer approximately 2 hours before the procedure
PALATABILITY: A controlled palatability study was conducted which demonstrated that Rimadyl chewable tablets were readily accepted and consumed on first offering by a majority of dogs.
EFFECTIVENESS: Confirmation of the effectiveness of Rimadyl for the relief of pain and inflammation associated with osteoarthritis, and for the control of postoperative pain associated with soft tissue and orthopedic surgeries, was demonstrated in 7 placebo-controlled, masked studies examining the anti-inflammatory and analgesic effectiveness of Rimadyl caplets and injectable in various breeds of dogs.
Separate placebo-controlled, masked, multicenter field studies confirmed the anti-inflammatory and analgesic effectiveness of Rimadyl caplets when dosed at 2 mg/lb once daily or when divided and administered at 1 mg/lb twice daily. In these 2 field studies, dogs diagnosed with osteoarthritis showed statistically significant overall improvement based on lameness evaluations by the veterinarian and owner observations when administered Rimadyl at labeled doses.
Based upon the blood level comparison between subcutaneous and oral administration, Rimadyl effectiveness for osteoarthritis after dorsoscapular subcutaneous and oral administration should be similar, although there may be a slight delay in the onset of relief after subcutaneous injection.
Separate placebo-controlled, masked, multicenter field studies confirmed the effectiveness of Rimadyl caplets and injectable for the control of postoperative pain when dosed at 2 mg/lb once daily in various breeds of dogs. In these studies, dogs presented for ovariohysterectomy, cruciate repair and aural surgeries were administered Rimadyl preoperatively and for a maximum of 3 days (soft tissue) or 4 days (orthopedic) postoperatively. In general, dogs administered Rimadyl showed a statistically significant reduction in pain scores compared to controls.
CONTRAINDICATIONS: Rimadyl should not be used in dogs exhibiting previous hypersensitivity to carprofen.
WARNINGS: Keep out of reach of children. Not for human use. Consult a physician in cases of accidental ingestion by humans. For use in dogs only. Do not use in cats.
All dogs should undergo a thorough history and physical examination before initiation of NSAID therapy. Appropriate laboratory tests to establish hematological and serum biochemical baseline data before, and periodically during, administration of any NSAID should be considered. Owners should be advised to observe for signs of potential drug toxicity (see Information for Dog Owners, Adverse Reactions, Animal Safety, and Post-Approval Experience).
What is Rimadyl?
Rimadyl is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce pain and inflammation (soreness) due to osteoarthritis and surgery in dogs. A licensed veterinarian must prescribe Rimadyl for your dog. It is available as a caplet and chewable tablet and is given to dogs by mouth.
Osteoarthritis (OA) is a painful condition caused by "wear and tear" of cartilage and other parts of the joints that may result in the following changes or signs in your dog:
To control surgical pain (for example, for surgeries such as spays, ear procedures or orthopedic repairs), your veterinarian may administer Rimadyl before the procedure and recommend that your dog be treated for several days after going home.
What kind of results can I expect when my dog is on Rimadyl for OA?
While Rimadyl is not a cure for osteoarthritis, it can relieve the pain and inflammation of OA and improve your dog's mobility.
What should not take Rimadyl?
Your dog should not be given Rimadyl if he/she:
Rimadyl should be given to dogs only. Cats should not be given Rimadyl, Call your veterinarian immediately if your cat receives Rimadyl. People should not take Rimadyl. Keep Rimadyl and all medicines out of reach of children. Call your physician immediately if you accidentally take Rimadyl.
How to give Rimadyl to your dog.
Rimadyl should be given according to your veterinarian's instructions. Your veterinarian will tell you what amount of Rimadyl is right for your dog and for how long it should be given. Rimadyl Caplets should be given by mouth. Most dogs will take Rimadyl Chewable Tablets right out of your hand or the tablet can be placed in the mouth. Rimadyl may be given with or without food.
What to tell/ask your veterinarian before giving Rimadyl.
Talk to your veterinarian about:
Tell your veterinarian if your dog has ever had the following medical problems:
Tell your veterinarian about:
Tell your veterinarian if your dog is:
What are the possible side effects that may occur in my dog during Rimadyl therapy?
Rimadyl, like other drugs, may cause some side effects. Serious but rare side effects have been reported in dogs taking NSAIDs, including Rimadyl. Serious side effects can occur with or without warning and in rare situations result in death.
The most common NSAID-related side effects generally involve the stomach (such as bleeding ulcers). Kidneys and liver can also be affected. Look for the following side effects that can indicate your dog may be having a problem with Rimadyl or may have another medical problem:
It is important to stop therapy and contact your veterinarian immediately if you think your dog has a medical problem or side effect from Rimadyl therapy. If you have additional questions about possible side effects, talk to your veterinarian.
Can Rimadyl be given with other medicines?
Rimadyl should not be given with other NSAIDs (for example, aspirin, etodolac) or steroids (for example, cortisone, prednisone, dexamethasone, triamcinolone).
Tell your veterinarian about all medicines you have given your dog in the past, and any medicines that you are planning to give with Rimadyl. This should include other medicines that you can get without a prescription. Your veterinarian may want to check that all of your dog's medicines can be given together.
What do I do in case my dog eats more than the prescribed amount of Rimadyl?
Contact your veterinarian immediately if your dog eats more than the prescribed amount of Rimadyl.