Vetprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to reduce pain and inflammation (soreness) due to osteoarthritis and pain following surgery in dogs. Vetprofen Flavored Tab is a prescription drug for dogs. It is available as a tablet and is given to dogs by mouth.
Osteoarthritis (OA) is painful condition caused by “wear and tear” of cartilage and other parts of the joints that may result in the following changes or signs in your dog:
To control surgical pain (e.g. for surgeries such as spays, ear procedures or orthopedic repairs) your veterinarian may administer Vetprofen Flavored Tab before the procedure and recommend that your dog be treated for several days after going home.
Always provide Client Information Sheet with prescription. The recommended dosage for oral administration to dogs is 2 mg/lb (4.4 mg/kg) of body weight daily. The total daily dose may be administered as 2 mg/lb of body weight once daily or divided and administered as 1 mg/lb (2.2 mg/kg) twice daily. For the control of postoperative pain, administer approximately 2 hours before the procedure. Caplets are scored, and dosage should be calculated in half-caplet increments.
EFFECTIVENESS: Confirmation of the effectiveness of carprofen for the relief of pain and inflammation associated with osteoarthritis, and for the control of postoperative pain associated with soft tissue and orthopedic surgeries was demonstrated in 5 placebo-controlled, masked studies examining the anti-inflammatory and analgesic effectiveness of carprofen caplets in various breeds of dogs.
Separate placebo-controlled, masked, multicenter field studies confirmed the anti-inflammatory and analgesic effectiveness of carprofen caplets when dosed at 2 mg/lb once daily or when divided and administered at 1 mg/lb twice daily. In these two field studies, dogs diagnosed with osteoarthritis showed statistically significant overall improvement based on lameness evaluations by the veterinarian and owner observations when administered carprofen at labeled doses.
Separate placebo-controlled, masked, multicenter field studies confirmed the effectiveness of carprofen caplets for the control of postoperative pain when dosed at 2 mg/lb once daily in various breeds of dogs. In these studies, dogs presented for ovariohysterectomy, cruciate repair, and aural surgeries were administered carprofen preoperatively and for a maximum of 3 days (soft tissue) or 4 days (orthopedic) postoperatively. In general, dogs administered carprofen showed statistically significant improvement in pain scores compared to controls.
INDICATIONS: Vetprofen is indicated for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
CONTRAINDICATIONS: Vetprofen should not be used in dogs exhibiting previous hyper- sensitivity to carprofen.
WARNINGS: Keep out of reach of children. Not for human use. Consult a physician in cases of accidental ingestion by humans. For use in dogs only. Do not use in cats. All dogs should undergo a thorough history and physical examination before initiation of NSAID therapy. Appropriate laboratory tests to establish hematological and serum biochemical baseline data before, and periodically during, administration of any NSAID should be considered. Owners should be advised to observe for signs of potential drug toxicity (see Information for Dog Owners, Adverse Reactions, Animal Safety, and Post-Approval Experience).
INFORMATION FOR DOG OWNERS: Vetprofen, like other drugs of its class, is not free from adverse reactions. Owners should be advised of the potential for adverse reactions and be informed of the clinical signs associated with drug intolerance. Adverse reactions may include decreased appetite, vomiting, diarrhea, dark or tarry stools, increased water consumption, increased urination, pale gums due to anemia, yellowing of gums, skin or white of the eye due to jaundice, lethargy, incoordination, seizure, or behavioral changes. Serious adverse reactions associated with this drug class can occur without warning and in rare situations result in death (see Adverse Reactions). Owners should be advised to discontinue Vetprofen therapy and contact their veterinarian immediately if signs of intolerance are observed. The vast majority of patients with drug related adverse reactions have recovered when the signs are recognized, the drug is withdrawn, and veterinary care, if appropriate, is initiated. Owners should be advised of the importance of periodic follow up for all dogs during administration of any NSAID.
What kind of results can I expect when my dog is on Vetprofen? While Vetprofen is not a cure for osteoarthritis, it can relieve the pain and inflammation of OA and improve your dog's mobility.
Who should not take Vetprofen? Your dog should not be given Vetprofen if he/she:
Vetprofen should be given to dogs only. Cats should not be given Vetprofen. Call your veterinarian immediately if your cat receives Vetprofen. People should not take Vetprofen. Keep Vetprofen and all medicines out of reach of children. Call your physician immediately if you accidentally take Vetprofen.
How to give Vetprofen to your dog. Vetprofen should be given according to your veterinarian's instructions. Your veterinarian will tell you what amount of Vetprofen is right for your dog and for how long it should be given. Vetprofen should be given by mouth and may be given with or without food.
What to tell/ask your veterinarian before giving Vetprofen. Talk to your veterinarian about:
What are the possible side effects that may occur in my dog during Vetprofen therapy? Vetprofen, like other drugs, may cause some side effects. Serious but rare side effects have been reported in dogs taking NSAIDs, including carprofen. Serious side effects can occur with or without warning and in rare situations result in death.
The most common NSAID-related side effects generally involve the stomach (such as bleeding ulcers), and liver or kidney problems. Look for the following side effects that can indicate your dog may be having a problem with Vetprofen or may have another medical problem:
it is important to stop therapy and contact your veterinarian immediately if you think your dog has a medical problem or side effect from Vetprofen therapy. If you have additional questions about possible side effects, talk to your veterinarian.
Can Vetprofen be given with other medicines? Vetprofen should not be given with other NSAIDs (for example, aspirin, deracoxib, etodolac, firocoxib, meloxicam, tepoxalin) or steroids (for example, cortisone, dexamethasone, prednisone, triamcinolone).
Tell your veterinarian about all medicines you have given your dog in the past, and any medicines that you are planning to give with Vetprofen. This should include other medicines that you can get without a prescription. Your veterinarian may want to check that all of your dog's medicines can be given together.
What do I do in case my dog eats more than the prescribed amount of Vetprofen? Contact your veterinarian immediately if your dog eats more than the prescribed amount of Vetprofen.