Sentinel Flavor Tabs is a preventive for heartworms, adult roundworms, adult hookworms and whipworms for your dog. Sentinel also prevents the development of flea eggs on your pet by breaking the flea life cycle. Sentinel can be taken along with Capstar for a more thorough flea treatment program. Sentinel requires a prescription from a veterinarian in order to be dispensed to your pet.
Sentinel Flavor Tabs are indicated for use in dogs and puppies, four weeks of age and older, and two pounds body weight or greater. Sentinel Flavor Tabs are also indicated for the prevention of heartworm disease caused by Dirofilaria immitis for the prevention and control of flea populations, the control of adult Ancylostoma caninum (hookworm), and the removal and control of adult Toxocara canis and Toxascaris leonina (roundworm) and Trichuris vulpis (whipworm) infections.
Lufenuron controls flea populations by preventing the development of flea eggs and does not kill adult fleas. Concurrent use of an adulticide product may be necessary for adequate control of adult fleas.
Without concurrent use of an adulticide, adequate flea control may not be achieved in dogs that have repeated exposure to flea-infested animals or environments.
Milbemycin oxime eliminates the tissue stage of heartworm larvae and the adult stage of hookworm, roundworm, and whipworm infestations. Lufenuron, the other active ingredient, is an insect development inhibitor that breaks the flea life cycle by inhibiting egg development. Lufenuron prevents most flea eggs from hatching or maturing into adults and thus prevents and controls flea populations by breaking the life cycle.
Do not use in puppies less than four weeks of age and less than two pounds of body weight. Dogs should be tested for existing heartworm infections prior to initiating treatment with Sentinel Flavor Tabs. Infected dogs should be treated to remove adult heartworms and microfilariae prior to initiating treatment with Sentinel Flavor Tabs.
|Active Ingredient (per tablet)||Milbemycin Oxime||Lufenuron|
|Sentinel Brown||2.3 mg||46 mg|
|Sentinel Green||5.75 mg||115 mg|
|Sentinel Yellow||11.5 mg||230 mg|
|Sentinel White||23 mg||460 mg|
Milbemycin oxime provided complete protection against heartworm infection in both controlled laboratory and clinical trials.
In laboratory studies, a single dose of milbemycin oxime at 0.5 mg/kg was effective in removing roundworm, hookworm and whipworm. In well-controlled clinical trials, milbemycin oxime was also effective in removing roundworms and whipworms and in controlling hookworms.
Lufenuron provided 99% control of flea egg development for 32 days following a single dose of lufenuron at 10 mg/kg in studies using experimental flea infestations. In well-controlled clinical trials, when treatment with lufenuron tablets was initiated prior to the flea season, mean flea counts were lower in lufenuron-treated dogs versus placebo-treated dogs. After 6 monthly treatments, the mean number of fleas on lufenuron-treated dogs was approximately 4 compared to 230 on placebo-treated dogs.
When treatment was initiated during the flea season, lufenuron tablets were effective in controlling flea infestations on dogs that completed the study. The mean flea count per lufenuron-treated dog was approximately 74 prior to treatment but had decreased to 4 after six monthly doses of lufenuron. A topical adulticide was used in the first eight weeks of the study to kill the pre-existing adult fleas.
Give Sentinel exactly as directed by the veterinarian. If you do not understand the directions ask your pharmacist or veterinarian to explain them to you. The usual dose of Sentinel for dogs 2 to 10 pounds is 2.3mg/46mg, 11 to 25 pounds is 5.75mg/115mg, 26 to 50 pounds is 11.5mg/230mg and 51 to 100 pounds is 23mg/460mg given once a month year-round. For dogs over 100 pounds give the appropriate combination of tablets.
Heartworm testing should be performed prior to the start of prevention therapy. If your pet is off Sentinel for 6 months or less, re-start the medication and test after 6 months since microfilaria, that take 6 months to mature, will result in a positive test result. Store Sentinel at room temperature. Do not remove the tablet from its wrapper until ready to give the medicine. Keep this medication away from children and pets. Consult your veterinarian for pregnant or lactating dogs.
|2-10 lbs||One Tablet (Brown)|
|11-25 lbs||One Tablet (Green)|
|26-50 lbs||One Tablet (Yellow)|
|51-100 lbs||One Tablet (White)|
|Over 100 lbs||Give combination of Flavor Tabs based on weight|
Should be stored at room temperature between 59° and 77°F (15-25°C). Keep out of reach of children.
Not for human use. Keep this and all drugs out of the reach of children.
The following adverse reactions have been reported in dogs after giving milbemycin oxime or lufenuron: vomiting, depression/lethargy, pruritus, urticaria, diarrhea, anorexia, skin congestion, ataxia, convulsions, hypersalivation, and weakness.
For optimal protection against 5 kinds of parasites, including fleas and heartworms, you should administer Sentinel Flavor Tabs every 30 days.
Sentinel Flavor Tabs are chewable tablets that are given by mouth along with a meal. Giving the product with a meal helps ensure full absorption of the medicine.
Both products protect dogs against heartworms, roundworms, and hookworms, but Sentinel Flavor Tabs also protect against 2 important and common parasites that Heartgard Plus doesn’t: fleas and whipworms.
In addition to providing flea and heartworm protection, you’ll also be protecting your dog against common intestinal parasites—roundworms, hookworms, and whipworms.