Simparica (sarolaner) Chewables Tablets for Dogs
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Simparica (sarolaner) Chewables Tablets for Dogs

Simparica (sarolaner) Chewables Tablets for Dogs

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Simparica™ (sarolaner) chewables are a safe monthly chewable for dogs that offers persistent protection from fleas and ticks. Simparica™ acts fast - starts killing fleas within 3 hours and ticks within 8 hours. Each chewable contains 5 mg of sarolaner.

Simparica™ is a flavored, chewable tablet for administration to dogs over 6 months of age according to their weight. Each tablet is formulated to provide a minimum sarolaner dosage of 0.91 mg/lb (2 mg/kg) body weight.


Prescription Required


Sarolaner, Hydrolyzed Soy Protein, Starch, Corn, Wheat Germ, Anhydrous Dibasic Calcium Phosphate, Corn Syrup, Gelatin


Simparica is given orally once a month at the recommended minimum dosage of 0.91 mg/lb (2 mg/kg).

View Simparica Drug Facts Sheet.

Body Weight Sarolaner per Tablet (mg) Number of Tablets Administered
2.8 to 5.5 lbs. 5 One
5.6 to 11.0 lbs. 10 One
11.1 to 22.0 lbs. 20 One
22.1 to 44.0 lbs. 40 One
44.1 to 88.0 lbs. 80 One
88.1 to 132.0 lbs. 120 One
>132.1 lbs. Administer the appropriate combination of tablets

Simparica can be offered by hand, in the food, or administered like other tablet medications. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If a dose is missed, administer Simparica and resume a monthly dosing schedule.

Simparica should be administered at monthly intervals.

Flea Treatment and Prevention:

Treatment with Simparica may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with Simparica can continue the entire year without interruption.

To minimize the likelihood of flea re-infestation, it is important to treat all dogs and cats within a household with an approved flea control product.

TIck Treatment and Control: Treatment with Simparica can begin at any time of the year (see Effectivenes).

Contraindications: There are no known containdications for the use of Simparica.

Warnings: Not for use in humans. Keep this and all drugs out of reach of children and pets. For use in dogs only. Do not use Simparica in cats. Simparica should not be used in dogs less than 6 months of age (see Animal Safety).

Precautions: Simparica may cause abnormal neurologic signs such as tremors, decreased conscious proprioception, ataxia, decreased or absent menace, and/or seizures (see Animal Safety). The safe use of Simparica has not been evaluated in breeding, pregnant, or lactating dogs.


Review Summary
8 Reviews
88% (7)
0% (0)
0% (0)
0% (0)
13% (1)
88% Recommend this product (7 of 8 responses)
By Joanne
MS gulf coast
Happy Pup
August 22, 2019
We adopted a heartworm positive dog. Following 3 months of treatment, our vet recommended the heartworm prevention shots & Simparica for monthly flea & tick prevention. Our dog loves Simparica & eats it from our hands like a treat.
ProsPup likes the product & it isn't a topical treatment that rubs off on our hands or other items. No fleas nor ticks bothering us or the pup.
By Allison
August 18, 2019
Arrived timely. Excellent price! They contacted my vet! It’s the same medication we receive from the vet but cheaper!!!!
By Gudrun B.
Simparica oral flea treatment for dogs
October 17, 2018
This prescription oral flea treatment works great for my dog, no more messy ointments. She has not had any adverse reactions to the medication.

It's not cheap but it's worth it.

Good product.

By Annie
June 10, 2018
Chewables are so easy to use. This is also an excellent price.
Merchant Response:Dear Annie, It's great to hear that the Simparica chewables are easy to use and to your satisfaction. EntirelyPets Pharmacy appreciates your business.
ProsEasy to use.
By Patty M.
Very satisfied
May 16, 2018
I like using a chewable flea medication instead of a tropical one. I was using Nexguard until my Vet told me about Simparica. She said it’s as safe and as effective as Nexguard, and it’s less expensive.
That really helps especially when you have multiple dogs!
By Rich
March 7, 2018
Entirelypets Pharmacy is a great place to get your meds for your pet. Great communication and customer service is awesome!
ProsGreat communication, awesome customer service, and great prices
By JuicyJ
Shipping is SLOW!
February 21, 2018
I've ordered from them 3-4 times now and their ordering processing is terribly slow. It took 2 weeks for this order to ship for a Rx that has unlimited refills! Seeking another company to order my dog's Rx from as they continue to disappoint.
ConsSLOW shipping
By Lisa J.
Galveston TX
Great product
July 2, 2017
I have tried them all and this works the best for my dogs. We have a lot of fleas here and the summer time it's brutal. Simperica works great and works all month. I have a finicky chi and the Simperica is small enough and doesn't have a foul odor..
ProsSmall, no foul odor