300 PRO LA a versatile, broad-spectrum antibiotic available only through veterinarians. Its high cure rate and longer duration make it ideal for multiple treatment protocols including where BRD metaphylaxis is indicated. 300 PRO LA® is approved for use in beef cattle, non-lactating dairy cattle, calves, pre-ruminating (veal) calves and swine.
Beef catte, non-lactating dairy cattle, calves, including pre-ruminating, (veal) calves:
A single intramuscular or subcutaneous dosage of 13.6mg of oxytetracycline per pound of bodyweight, 300 PRO LA is recommended for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia (Passteurella) haemolytica.
At a single intramuscular or subcutaneous dose range of 9 to 13.6 mg of oxytetracycline per pound of bodyweight, 300 PRO LA is recommended in the treatment of the following conditions:
For other indications 300 PRO LA is to be administered intramuscularly, subcutaneously or intravenously at a level of 3 to 5 mg of oxytetracycline per pound of bodyweight per day. In treatment of foot-rot and advanced cases of other indicated diseases, a dosage level of 5 mg per pound of bodyweight per day is recommended. Treatment should be continued 24 to 48 hours following remission of disease signs, however, not to exceed a total of four consecutive days. If improvement is not noted within 24 to 48 hours of the beginning of treatment, diagnosis and therapy should be re-evaluated.
Do not administer intramuscularly in the neck of small calves due to lack of sufficient muscle mass. Use extreme care when administering this product by intravenous injection. Perivascular injection or leakage from an intravenous injection may cause severe swelling at the injection site.
Swine: A single dosage of 9 mg of oxytetracycline per pound of bodyweight administered intramuscularly is recommended in the treatment of bacterial pneumonia caused by Pasteurella multocida in swine, where retreatment is impractical due to husbandry conditions or where repeated restrain is inadvisable.
300 PRO LA can also be administered by intramuscular injection at a level of 3 to 5 mg of oxytetracycline per pound of bodyweight per day. Treatment should be continued 24 to 49 hours following remission of disease signs; however, not to exceed a total of four consecutive days. If improvement is not noted within 24 to 48 hours of the beginning of treatment, diagnosis and therapy should be re-evaluated.
For sows, administer once intramuscularly 3 mg of oxytetracycline per pound of bodyweight approximately eight hours before farrowing or immediately after completion of farrowing as an aid in the control of infectious enteritis in baby pigs.
For swine weighing 25 lbs of bodyweight and under, 300 PRO LA should be administered undiluted for treatment at 9mg/lb should be administered diluted for treatment at 3 or 5 mg/lg
|9mg dosage undiluted 300 PRO LA||3 or 5 mg/lb volume of diluted 300 PRO LA|
|Bodyweight||9 mg/lb||3 mg/lb||Dilution*||5 mg/lb|
|5 lb||0.15 mL||0.4 mL||37.5 mg/mL||0.7 mL|
|10 lb||0.30 mL||0.6 mL||50 mg/mL||1.0 mL|
|25 lb||0.75 mL||1.0 mL||75 mg/mL||1.7 mL|
*To prepare dilutions, add one part of 300 PRO LA to three, five or seven parts of the sterile water, or 55 dextrose solution as indicated; the diluted product should be used immediately.
PRECAUTIONS: Exceeding the highest recommended level of drug per pound of bodyweight per day, adminsitering more than the recommended number of treatments, and/or exceeding 10mL intramuscularly or subcutaneously per injection site in adult beef cattle and non-lactating dairy cattle and 5mL intramuscularly per injection site in adult swine, may result in antibiotic residues beyond the withdrawal time.
Consult with you veterinarian prior to administering this product in order to determine the proper treatment required in the event of an adverse reaction. At the first sign of any adverse reaction, discontinue use of the product and seek the advice of your veterinarian. Some of the reactions may be attributable either to anaphylaxis (an allergic reaction) or to cardiovascular collapse of unknown cause.
Shortly after injection treated animals may have transient hemoglobinuria resulting in darkened urine.
As with all antibiotic preparations, use of this drug may result in overgrowth of non-susceptible organisms, including fungi. The absence of a favourable response following treatment, or the development of new signs or symptoms may suggest an overgrowth of non-susceptible organisms. If superinfections occur, the use of this product should be discontinued and appropriate specific therapy should be instituted.
Since bacteriostatic drugs may intergere with the bactericidal action of penicillin, it is advisable to avoid giving 300 PRO LA in conjuction with penicillin.