Prednisolone Acetate Ophthalmic Suspension

Prednisolone Acetate Ophthalmic Suspension is in a class called corticosteroids. It is used to inhibit inflammation and, therefore, swelling and pain from inflammation are lessened. Prednisolone Acetate Ophthalmic Suspension 1% is used to treat eye inflammation caused by infections, injury, surgery, or other conditions. Additionally, Prednisolone Acetate Ophthalmic Suspension 1% may also be used for purposes other than those listed.

Key Benefits

• Decreases inflammation in the eye
• Convenient easy-dose dropper bottle
• Lessens burning and redness

Prednisolone Acetate Ophthalmic Suspension is prescribed to decrease inflammation due to conditions such as conjunctivitis (inflammation of the lining of the lids) and some types of keratitis (inflammation of the cornea).

How It Works

It is a synthetic corticosteroid that that blocks the production of substances that trigger allergic and inflammatory actions.

Indications

Prednisolone acetate ophthalmic suspension 1% is indicated for the treatment of steroid-responsiveinflammation of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe.

• Prednisolone Acetate Ophthalmic Suspension 1% is a prescription corticosteroid eye drop.
• Prednisolone Acetate Ophthalmic 1% is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to prescribe this product for dogs and horses
• Prednisolone Acetate Ophthalmic Suspension 1% is used in dogs and horses to treat eye inflammation caused by infections, injury, surgery, or other conditions. It is used to inhibit inflammation and, therefore, swelling and pain from inflammation are lessened.
• Prednisolone Acetate Ophthalmic Suspension 1% is also used to treat swelling, itching, redness, and irritation of the eyes and eyelids.

Always follow the dosage instructions provided by your veterinarian. If you have difficulty applying the medication, contact your veterinarian. If discharge is present, the area should be cleansed with a sterile eyewash solution prior to applying Prednisolone acetate ophthalmic suspension.

Shake the solution well before using. Place one hand under and around your pet's chin and lift upward, so the pet's eyes are looking towards the ceiling. Rest your other hand, holding the bottle, on top of the pet's head. Be sure the tip of the bottle is pointed away from your pet's eye so if your pet jerks, the tip will not injure the eye. Hold the bottle about one inch from the eye. Squeeze the drops into the corner of the eye, taking care not to touch the dropper to the eye surface. Continue to hold the head back for a moment while the drops disperse over the whole eye surface.

Always wash your hands before and after applying this medication. If you are applying more than one medication to the eye, allow 5 minutes between applications so one medication is not washed out by the next. Be sure not to interchange the caps of the medications.

This medication should only be given to the pet for whom it was prescribed.

Caution:

Before using Prednisolone Acetate Ophthalmic Suspension 1%, tell your veterinarian if your pet is using other eye drops or eye medications. If your pet has swelling of the face, itching, or appears to have difficulty breathing, contact your veterinarian immediately. Do not touch the dropper opening to any surface including eyes or hands. This medication may cause blurred vision.

Contraindications

Prednisolone acetate ophthalmic suspension 1% is contraindicated in most viral diseases of the corneaand conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella,and also in mycobacterial infection of the eye and fungal diseases of ocular structures. Prednisoloneacetate ophthalmic suspension 1% is also contraindicated in individuals with known or suspectedhypersensitivity to any of the ingredients of this preparation and to other corticosteroids.

Warnings:

Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, defects invisual acuity and fields of vision, and in posterior subcapsular cataract formation. Prolonged use mayalso suppress the host immune response and thus increase the hazard of secondary ocular infections.

Various ocular diseases and long-term use of topical corticosteroids have been known to cause cornealand scleral thinning. Use of topical corticosteroids in the presence of thin corneal or scleral tissue maylead to perforation.

Acute purulent infections of the eye may be masked or activity enhanced by the presence ofcorticosteroid medication.

If this product is used for 10 days or longer, intraocular pressure should be routinely monitored eventhough it may be difficult in children and uncooperative patients. Steroids should be used with caution inthe presence of glaucoma. Intraocular pressure should be checked frequently.

The use of steroids after cataract surgery may delay healing and increase the incidence of blebformation.

Use of ocular steroids may prolong the course and may exacerbate the severity of many viral infectionsof the eye (including herpes simplex). Employment of a corticosteroid medication in the treatment of patients with a history of herpes simplex requires great caution; frequent slit lamp microscopy isrecommended.

Corticosteroids are not effective in mustard gas keratitis and Sjögren's keratoconjunctivitis.

Contains sodium bisulfite, a sulfite that may cause allergic-type reactions, including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. Theoverall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.

Storage:

Store this product at room temperature, away from moisture and heat. Keep the bottle properly capped.

Precautions

The initial prescription and renewal of the medication order beyond 20 milliliters of prednisolone acetate ophthalmic suspension 1% should be made by a physician only after examination of the patient with the aid of magnification, such as slit lamp biomicroscopy, and, where appropriate, fluoresceinstaining. If signs and symptoms fail to improve after 2 days, the patient should be re-evaluated.

As fungal infections of the cornea are particularly prone to develop coincidentally with long-term localcorticosteroid applications, fungal invasion should be suspected in any persistent corneal ulcerationwhere a corticosteroid has been used or is in use. Fungal cultures should be taken when appropriate.

If this product is used for 10 days or longer, intraocular pressure should be monitored.