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Deramaxx Chewable Tablets for Dogs

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  • Description
  • Ingredients
  • Directions
  • FAQ
  • Reviews

Description

Deramaxx is a non-steroidal anti-inflammatory drug (NSAID) used in dogs to control pain and inflammation. It is particularly effective against osteoarthritis, a degenerative disease that affects your dog's joints. It is available as beef-flavored, scored, chewable tablets. Deramaxx works by reducing substances that cause pain, inflammation, and fever in the body. Deramaxx is also used to reduce pain associated with surgery or dental procedures. Deramaxx requires a prescription from your veterinarian.

Key Benefits

  • Effectively controls pain and inflammation
  • Pain-free dogs may be more active and less likely to become overweight
  • Controls the pain of Osteoarthritis associated with walking, climbing, standing, and sitting.
  • Makes your pet more comfortable, ensuring more refreshing rest and sleep.

How It Works

Deramaxx is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the COX-2 inhibitor class of medications. Deramaxx is different from other NSAIDs because at recommended doses it blocks the COX-2 enzyme, not the COX-1 enzyme. While the COX-1 enzyme is necessary for many normal body functions, COX-2 enzymes trigger inflammation and contribute to pain in arthritic joints.

Indications

Always provide "Information for Dog Owners" Sheet with prescription. Carefully consider the potential benefits and risk of Deramaxx and other treatment options before deciding to use Deramaxx. Use the lowest effective dose for the shortest duration consistent with individual response.

Ingredients

Deramaxx 12 mg tablets:
Active Ingredients Amount
Deracoxib 12 mg
Deramaxx 25 mg tablets:
Active Ingredients Amount
Deracoxib 25 mg
Deramaxx 75 mg tablets:
Active Ingredients Amount
Deracoxib 75 mg
Deramaxx 100 mg tablets:
Active Ingredients Amount
Deracoxib 100 mg

Directions

View Deramaxx Drug Facts Sheet.

Indications and Usage:

Always provide "information for Dog Owners" Sheet with prescription. Carefully consider the potential benefits and risk of Deramaxx and other treatment options before deciding to use Deramaxx Use the lowest effective dose for the shortest duration consistent with individual response.

Osteoarthritis Pain and Inflammation:

Deramaxx Chewable Tablets are indicated for the control of pain and inflammation associated with osteoarthritis in dogs.

Dosage and Administration:

Osteoarthritis Pain and Inflammation: 0.45-0.91 mg/lb/day (1 to 2 mg/kg/day) as a single daily dose, as needed.

Dogs needing in a dose of less than 12.5 mg can only be accurately dosed through use of the 12 mg tablet, which can be broken in half to provide 6 mg. Do not attempt to accurately dose smaller dogs through the use of breaking larger tablets. Inaccurate dosing may result in adverse drug events (see Adverse Reactions, Animal Safety, and Post-Approval Experience).

Postoperative Orthopedic Pain and Inflammation:

Deramaxx Chewable Tablets are indicated for the control of postoperative pain and inflammation associated with orthopedic surgery in dogs.

Dosage and Administration:

Postoperative Orthopedic Pain and Inflammation: 1.4-1.8 mg/lb/day (3 to 4 mg/kg/day) as a single daily dose, as needed, not exceed 7 days of administration.

Dogs needing a dose of less than 12.5 mg can only be accurately dose through use of the 12 mg tablet, which can be broken in half to provide 6 mg. Do not attempt to accurately dose smaller dogs through the use of breaking larger tablets. Inaccurate dosing may result in adverse drug events (see Adverse Reactions, Animal Safety and Post-Approval Experience).

Postoperative Dental Pain and Inflammation:

Deramaxx Chewable Tablets are indicated for the control of postoperative pain and inflammation associated with dental surgery in dogs.

Dosage and Administration:

Postoperative Dental Pain and Inflammation: 0.45-0.91 mg/lb/day (1 to 2 mg mg/kg/day) as a single daily dose, for 3 days. The first dose should be given approximately 1 hour prior to dental surgery and subsequent doses should be given daily for up to two additional treatments.

Dogs needing a dose of less than 12.5 mg can only be accurately dosed through use of the 12 mg tablet, which can be broken in half to provide 6 mg. Do not attempt to accurately dose smaller dogs through the use of breaking larger tablets. Inaccurate dosing may result in adverse drug events (see Adverse Reactions, Animal Safety, and Post-Approval Experience).

Since Deramaxx tablet bioavailability is greatest when taken with food, postprandial administration is preferable. However, Deramaxx tablets have been shown to be effective under both fed and fasted conditions; therefore, they may be administered in the fasted state if necessary. For postoperative orthopedic and dental pain, administer Deramaxx tablets prior to the procedure. Tablets are scored and dosage should be calculated in half-tablet increments. In clinical practice it is recommended to adjust the individual patient dose while continuing to monitor the dog's status until a minimum effective dose has been reached.

Dogs at risk for osteoarthritis:

  • Are over the age of five
  • Are inactive or overweight
  • Are large or giant breed dogs
  • Have suffered joint injuries
  • Are predisposed to developmental orthopedic disorders such as hip or elbow dysplasia

Signs of pain from Canine Osteoarthritis

  • Reluctance to climb stairs
  • Stiffness after strenuous exercise or after the rest period following exercise
  • Limping
  • Difficulty rising, sitting or squatting to defecate or urinate
  • Changes in behavior
  • Loss of appetite

Contraindications:

Dogs with known hypersensitivity to deracoxib should not receive Deramaxx.

Warnings:

Not for use in humans. Keep this and all medications out of reach of children. Consult a physician in case of accidental ingestion by humans. For use in dogs only. Do not use in cats.

Dogs needing a dose of less than 12.5 mg can only be accurately dosed through use of the 12 mg tablet, which can be broken in half to provide 6 mg. Do not attempt to accurately dose smaller dogs through the use of breaking larger tablets. Inaccurate dosing may result in adverse drug events (see Adverse Reactions, Animal Safety, and Post-Approval Experience).

All dogs should undergo a thorough history and physical examination before the initiation of NSAID therapy. Appropriate laboratory tests to establish hematological and serum biochemical baseline data prior to, and periodically during, administration of any NSAID is recommended. Owners should be advised to observe for signs of potential drug toxicity (see Adverse Reactions, Animal Safety and Post-Approval Experience) and be given an "Information for Dog Owners" sheet.

Precautions:

Dogs needing a dose of less than 12.5 mg can only be accurately dose through use of the 12 mg tablet, which can be broken in half to provide 6 mg. Do not attempt to accurately dose smaller dogs through the use of breaking larger tablets. Inaccurate dosing may result in adverse drug events (see Adverse Reactions, Animal Safety, and Post-Approval Experience).

Since NSAIDs possess the potential to produce gastrointestinal ulceration and/or perforation, concomitant use of deramaxx tablets with other anti-inflammatory drugs, such as NSAIDs or corticosteroids, should be avoided, As a class, NSAIDs may be associated with gastrointestinal, renal and hepatic toxicity. The following collective group of clinical signs has been reported with some serious gastrointestinal events, in decreasing order of reported frequency: anorexia, tachycardia, tachypnea, pyrexia, ascites, pale mucous membranes, dyspnea. In some cases, circulatory shock, collapse and cardiac arrest have also been reported. Sensitivity to drug-associated adverse events varies with the individual patient.

Dogs that have experienced adverse reactions from one NSAID may experience adverse reactions from another NSAID. Patients at greatest risk for adverse events are those that are dehydrated, on concomitant diuretic therapy, or those with existing renal, cardiovascualr, and or hepatic dysfunction. Plasma levels of deracoxib may increase in a greater than dose-proportional fashion above 8 mg/kg/day. Deramaxx tablets have been safely used during field studies in conjunction with other common medications, including heartworm preventatives, anthelmintics, anesthetics, pre-anesthetic medications, and antibiotics.

If additional pain medication is needed after a daily dose of Deramaxx tablets, a non-NSAID/non-corticosteroid class of analgesic may be necessary. It is known whether dogs with a history of hypersensitivity to sulfonamide drugs will exhibit hypersensitivity to Deramaxx tablets. The safe use of Deramaxx tablets in dogs younger than 4 months of age, dogs used for breeding, or in pregnant or lactating dogs has not been evaluated.

NSAIDs may inhibit the prostaglandins which maintain normal homeostatic function. Such anti-oristaglandin effects may result in clinically significant disease in patients with underlying or pre-existing disease that has not been previously diagnosed.

Appropriate monitoring procedures should be employed during all surgical procedures. The use of parenteral fluids during surgery should be considered to decrease potential renal complications when using NSAIDs perioperatively. Concurrent administration of potentially nephrotoxic drugs should be carefully approached.

The use of concomitantly protein-bound drugs with Deramaxx tablets has not been studied in dogs. Commonly used protein-bound drugs include cardiac, anticonvulsant and behavioral medications. The influence of concomitant drugs that may inhibit metabolism of Deramaxx tablets has not been evaluated. Drug compatibility should be monitored in patients requiring adjunctive therapy. Consider appropriate washout times when switching from one NSAID to another or when switching from corticosteroid use to NSAID use.

Palatability:

Deramaxx tablets were evaluated for palatability in 100 client-owned dogs of variety of breeds and sizes. Dogs received two doses of Deramaxx tablets, one on each of two consecutive days. Deramaxx tablets were accepted by 94% of dogs on the first day of dosing and by 92% of dogs on the second day of dosing.

Effectiveness:

Deramaxx tablets were evaluated in masked, placebo-controlled multi-site field studies involving client-owned animals to determine effectiveness.

Information for Dog Owners:

Deramaxx like other drugs of its class, is not free from adverse reactions. Owners should be advised of the potential for adverse reactions and be informed of the clinical signs associated with drug intolerance. Adverse reactions may include vomiting, diarrhea, decreased appetite, dark or tarry stools, increase water consumption, increased urination, anemia, yellowing of gums, skin or white of the eye due to jaundice, lethargy, in-coordination, seizure, or behavioral changes. Serious adverse reactions with this drug class can occur without warning and in some cases result in death (see Warnings, Post-Approval Experience and Adverse Reactions). Owners should be advised to discontinue Deramaxx therapy and contact their veterinarian immediately if signs of intolerance are observed.

The vast majority of patients with drug related adverse reactions have recovered when the signs are recognized, the drug is withdrawn, and veterinary care, if appropriate, is initiated. Owners should be advised of the importance pr periodic follow up for all dogs during administration of any NSAID.

Storage:

Deramaxx tablets should be stored at room temperature between 59° and 86°F (15-30°C).

Keep this and all medications out of reach of children.

FAQ

Deramaxx tablets are a prescription non-steroidal anti-inflammatory drug (NSAID) of the coxib class. They are indicated for the control of postoperative pain and inflammation associated with orthopedic (bone) and dental surgery in dogs and for the control of pain and inflammation (soreness) associated with osteoarthritis in dogs. The tablets are flavored to make administration more convenient.

Deramaxx tablets allow your dog to recover more comfortably by controlling pain and inflammation that follow orthopedic and dental surgery.

  • The postoperative orthopedic pain dose is a higher dose; administration at this dose should not exceed 7 days total, including the days the patient is administered Deramaxx while in the hospital.
  • Control of pain and inflammation may vary from dog to dog.
  • If Deramaxx tablets are not given according to your veterinarian's directions, your dog's pain may return.
  • Consult your veterinarian if your dog appears to be uncomfortable.

Osteoarthritis is a painful condition caused by damage to cartilage and other parts of the joint that may result in the following changes or signs in your dog:

  • Limping or lameness
  • Decreased activity or exercise (reluctance to stand, climb stairs, jump or run, or difficulty in performing these activities)
  • Stiffness or decreased movement of joints

While Deramaxx is not a cure for osteoarthritis, it can control the pain and inflammation of osteoarthritis and improve your dog's mobility. Response may vary from dog to dog but can be quite dramatic. Deramaxx tablets may need to be given on a periodic basis for the animal's lifetime. Use the lowest dose to provide adequate relief. Always consult with your veterinarian before altering the dose.

Your dog should not be given Deramaxx tablets if she/he:

  • Has had an allergic reaction to deracoxib, the active ingredient in Deramaxx tablets
  • Has had an allergic reaction (such as hives, facial swelling, or red or itchy skin) to aspirin or other NSAIDs
  • Is presently taking aspirin, other NSAIDs, or corticosteroids (unless directed by your veterinarian)
  • Has bloody stool or vomit
  • Has a pre-existing kidney or liver condition
  • Has any condition predisposing to dehydration
  • Is anorexic (loss of appetite)

Tell your veterinarian about:

  • Any side effects your dog has experienced from Deramaxx tablets or other NSAIDs
  • Any digestive upset (vomiting or diarrhea) your dog has had
  • Any kidney disease your dog has had
  • Any other medical problems or allergies that your dog has now or has had in the past
  • All medications that you are giving your dog or plan to give your dog, including those you can get without prescription and any dietary supplements
  • If you plan to breed your dog, or if your dog is pregnant or nursing

Talk to your veterinarian about:

  • The orthopedic or dental surgery your dog will undergo
  • What tests might be done before surgery is performed or Deramaxx tablets are prescribed
  • The signs of pain or inflammation that may occur after surgery
  • Normal events that can be expected after your dog undergoes surgery
  • The proper amount of exercise after surgery to aid recovery
  • The signs of osteoarthritis you have observed (for example, limping or stiffness)
  • The importance of weight control, physical therapy and exercise in the management of osteoarthritis
  • How often your dog may need to be examined by your veterinarian
  • The risks and benefits of using Deramaxx tablets

Deramaxx tablets may cause some side effects in individual dogs. Serious side effects associated with this drug can occur with or without warning and, in some cases, result in death. The most common side effects associated with Deramaxx therapy involve the digestive tract (vomiting, decreased appetite and diarrhea). Liver and kidney problems have also been reported. It is important to stop the medication and contact your veterinarian immediately if you think your dog may have a medical problem or side effect while on Deramaxx tablets. If you have additional questions about possible side effects, talk with your veterinarian or call Elanco US Inc. at 1-888-545-5973.

Look for the following side effects that may indicate that your dog is having a problem with Deramaxx tablets or may have another medical problem:

  • Vomiting
  • Decrease in appetite
  • Change in behavior, such as depression, restlessness, aggression or apprehension
  • Change in bowel movements such as diarrhea or change in stool color (black, tarry or bloody stool)
  • Change in drinking or urination
  • Yellowing of gums, skin or whites of the eyes (jaundice)
Deramaxx tablets should not be given with other non-steroidal anti-inflammatory drugs (NSAID)s or corticosteroids (for example, aspirin, carprofen, etodolac, prednisone). Tell your veterinarian about all medications that you have given your dog in the past, and any medications that your are planning to give with Deramaxx tablets. This should include any medications that you can get without a prescription and any dietary supplements. Your veterinarian may want to evaluate the potential for any drug interactions and to assure drug compatibility.
Contact your veterinarian immediately if your dog eats more than the prescribed amount of Deramaxx tablets.

This sheet provides a summary of information about Deramaxx tablets. If you have any questions or concerns about Deramaxx tablets, postoperative orthopedic and dental pain and inflammation, or osteoarthritis, talk to your veterinarian.

As with all prescribed medications, Deramaxx tablets should only be given to the dog for which they are prescribed. They should be given to your dog only for the condition for which they were prescribed, at the prescribed dose, as directed by your veterinarian. It is important to periodically discuss your dog's response to Deramaxx tablets at regular checkups. Your veterinarian will best determine if your dog is responding as expected and if your dog should continue receiving Deramaxx tablets.

People should not take Deramaxx tablets. Keep Deramaxx tablets and all medication out of reach of children. Call your physician immediately if you accidentally take Deramaxx tablets.
Deramaxx tablets should be given according to your veterinarian's instructions. Your veterinarian will tell you what amount of Deramaxx tablets is right for your dog and for how long they should be given. Do not change the way you give Deramaxx tablets to your dog without first speaking with your veterinarian. Deramaxx tablets should be given by mouth and may be given with or without food, although with food is preferable.

Reviews

Review Summary
4.9
11 Reviews
5
91% (10)
4
9% (1)
3
0% (0)
2
0% (0)
1
0% (0)
100% Recommend this product (11 of 11 responses)
By Susan
Reseda, CA
My picky dog loves Joint Max
April 28, 2020
Great combo Deramaxx and joint max. We hide pills in the chews that our picky dog wont eat. Doesn't like peanut butter or pill pockets but loves these chews.
ProsGreat tasting... at least my dog thinks so. And seems to help.
ConsA little pricey.
By Debi
Marietta, GA
Great price for this medicine
June 4, 2015
Not sure how to review a prescribed drug but this has helped both of my dogs that are on it. They are older dogs dealing with some arthritis and one with hip dysplasia. Both get up and moving with much more ease after stating this.

Entirely Pets Pharmacy does in fact contact your vet to be sure this is actually prescribed for your pet and they do it very quickly. And since my dogs will be on this forever finding a better price than my vet can provide me was imperative and EP came up with the best price.
By Barbara
EVANSVILLE, IN
Top of the line medication.
April 20, 2020
My 191lb Newfoundland has been using this since injuring his knee 3 yrs ago.

Shows no signs of pain. Great product!
ProsWorks great in reducing the pain.
ConsCost- more expensive than others on the market.
By Kirby
Riverside CA
great service and price
January 30, 2020
quick service and great prices
Consnone
By Camsmom
Chesterfield, Missouri
Took years off my dog!
December 7, 2018
My 12 yr old lab/shepherd has arthritis in his rear and a sensitive stomach. He cannot take any other NSAID without getting really sick. Deramaxx took away his pain without getting him sick.
ProsEfficacy Less side effects Easy to give Lots of dosage levels
ConsPrice
By jsh
Perris
deramaxx
August 18, 2018
this item as prescribed by my vet has helped my old dog get around better
Merchant Response:Jsh, We are very glad to hear that Deramaxx helps your your dog. Both of you, take care.
By Brian
Nebraska
Great job.
August 7, 2018
They took care of everything I needed to get the prescription filled. It was easy to do and they save me a lot of money. I will definitely use them again.
Merchant Response:We are hard at work over here Brian. Thanks for your kind comments.
By Heather
California
Deramaxx
June 16, 2018
Has helped our dog tremendously.
Merchant Response:Hi Heather, Great to hear that Deramaxx is working wonders for your dog.
By Karen
Ohio
Medicine works, price not so much now
December 31, 2016
This medicine has been a lifesaver for my dog, but the price just went up and I don't know how much longer I can do this.
By Donna
Talala, OK
Good medicine, best service!
October 28, 2016
My 13 yr old Rottie has to have this medication on a daily basis. It's not cheap, but it cost way more from our vet. I was so,pleased to find it thru Entirely Pets pharmacy at such a good price. The service from contacting the vet to filling the script & getting it to me has been flawless. I am very pleased! Thank yo!
By Nancy
Chicago
Easy Rx Fill
April 16, 2015
Sammy will only eat this drug if I cut it in quarter pieces and hide it in a beef treat. It may be due to the nasal cancer changing his taste buds, or he is just really picky.
ProsEasy to fill this order.
ConsHe does seem to suffer from one of the side-effects which is dizziness. So look out for sign of that in your pet.

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