Ciprofloxacin Hydrochloride Ophthalmic Solution is a topical prescription antibiotic medication used to treat a wide variety of ophthalmic bacterial infections. Ciprofloxacin has been shown to be active against gram-positive microorganisms including Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, and Streptococcus (Viridans Group). Ciprofloxacin has been shown to be active against gram-negative microorganisms including Haemophilus influenzae, Pseudomonas aeruginosa, and Serratia marcescens. It is indicated in the treatment of external infections of the eye, such as conjunctivitis, corneal ulcer, blepharitis, keratitis, and other susceptible bacterial infections
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Ciprofloxacin Ophthalmic Solution
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Description
Ciprofloxacin Hydrochloride Ophthalmic Solution is a sterile topical antibiotic solution for the treatment of corneal ulcers, conjunctivitis, blepharitis, keratitis, and other susceptible bacterial infections of the eye in cats, dogs, and horses. The active ingredient, Ciprofloxacin, is a fluoroquinolone antibacterial that is active against a broad spectrum of gram-positive and gram-negative ocular pathogens.
Key Benefits
- Kills bacteria in the eye including conjunctivitis
- Safe for dogs and cats
- Dropper top for easier dosing
How It Works
Ciprofloxacin Hydrochloride Ophthalmic Solution is used to treat conjunctivitis as well as many other susceptible bacterial infections of the eye, including gram-positive and gram-negative pathogens that cause eye infection. It works by stopping bacteria from making DNA. This kills the bacteria and stops the infection.
Indications
Ciprofloxacin Ophthalmic Solution is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the conditions listed below:
Corneal Ulcers:
- Pseudomonas aeruginosa
- Serratia marcescens*
- Staphylococcus aureus
- Staphylococcus epidermidis
- Streptococcus pneumoniae
- Streptococcus (Viridans Group)*
Conjunctivitis:
- Haemophilus influenzae
- Staphylococcus aureus
- Staphylococcus epidermidis
- Streptococcus pneumoniae
*Efficacy for this organism was studied in fewer than 10 infections.
Directions
- Use according to your veterinarian's instructions.
- For Corneal Ulcers: The usual recommended dosage for corneal ulcers is two (2) drops into the affected eye every 15 minutes for the first six hours and then two (2) drops into the affected eye every 30 minutes for the remainder of the first day. On the second day, instill two drops in the affected eye hourly. On the third through the fourteenth days, place two drops in the affected eye every four hours. Treatment may be continued after 14 days if corneal re-epithelialization (wound healing) has not occurred.
- For Bacterial Conjunctivitis: The usual recommended dosage for bacterial conjunctivitis is 1-2 drops instilled into the conjunctival sac(s) every 2 hours while awake for two days and 1-2 drops every 4 hours while awake for the next 5 days.
Tip: Do not touch the dropper to any surface, including the surface of your pet's eye.
| Dosage for Cats, Dogs & Horses | |
|---|---|
| Weight | Dosage |
| All weights | Use as prescribed by your veterinarian. |
Caution:
Safe use in pregnant pets or pets intended for breeding has not been proven. If your pet's condition worsens or does not improve, stop product administration and consult your veterinarian. Ciprofloxacin Hydrochloride Ophthalmic Solution 0.3% is for topical ophthalmic use only. It is not for injection into the eye. Sensitivity to topically applied aminoglycosides may occur in some pets. If your pet has a reaction to Ciprofloxacin Hydrochloride Ophthalmic Solution 0.3%, discontinue use and consult your veterinarian.
Storage:
Store at 36°-77°F (2°-25°C).
Contraindications:
A history of hypersensitivity to ciprofloxacin or any other component of the medication is a contraindication to its use. A history of hypersensitivity to other quinolones may also contraindicate the use of ciprofloxacin.
Warnings:
Not for Injection into the Eye.
Serious and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported in patients receiving systemic quinolone therapy. Some reactions were accompanied by cardiovascular collapse, loss of consciousness, tingling, pharyngeal or facial edema, dyspnea, urticaria, and itching. Only a few patients had a history of hypersensitivity reactions. Serious anaphylactic reactions require immediate emergency treatment with epinephrine and other resuscitation measures, including oxygen, intravenous fluids, intravenous antihistamines, corticosteroids, pressor amines and airway management, as clinically indicated.
Remove contact lenses before using.
FAQ
Tell your veterinarian if your pet is known to have hypersensitivity to any ingredients in Ciprofloxacin Hydrochloride Ophthalmic Solution. Tell your veterinarian if your pet is pregnant, lactating or used for breeding purposes. Tell your veterinarian about any other medications your pet is currently being given.
The usual recommended dosage for corneal ulcers is two (2) drops into the affected eye every 15 minutes for the first six hours and then two (2) drops into the affected eye every 30 minutes for the remainder of the first day. On the second day, instill two drops in the affected eye hourly. On the third through the fourteenth days, place two drops in the affected eye every four hours. Treatment may be continued after 14 days if corneal re-epithelialization (wound healing) has not occurred.
The usual recommended dosage for bacterial conjunctivitis is 1-2 drops instilled into the conjunctival sac(s) every 2 hours while awake for two days and 1-2 drops every 4 hours while awake for the next 5 days.
Possible side effects of Ciprofloxacin Hydrochloride Ophthalmic Solution 0.3% include local burning or discomfort. Other less frequently occurring side effects include lid margin crusting, crystals/scales, foreign body sensation, itching, conjunctival hyperemia and a bad taste in the mouth following instillation.
Give the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and give the next regularly scheduled dose. Do not give a double dose unless otherwise directed by your veterinarian.
A topical overdose of Ciprofloxacin Hydrochloride Ophthalmic Solution 0.3% may be flushed from the eye(s) with warm tap water. If you suspect that your pet has ingested an overdose of Ciprofloxacin Hydrochloride Ophthalmic Solution 0.3%, consult your veterinarian or emergency veterinary clinic immediately.
Do not use Ciprofloxacin Hydrochloride Ophthalmic Solution 0.3% on pets with known hypersensitivity to any of its components. Ciprofloxacin Hydrochloride Ophthalmic Solution 0.3% is for topical ophthalmic use only. Not for injection into the eye. As with other antibiotic preparations, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. If superinfection occurs, appropriate therapy should be initiated. Whenever clinical judgment dictates, your pet should be examined with the aid of magnification, such as slit lamp biomicroscopy and, where appropriate, fluorescein staining. Ciprofloxacin should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity reaction. Do not touch dropper to any surface including the surface of the eye, as this may contaminate the solution.
Do not use Ciprofloxacin Hydrochloride Ophthalmic Solution 0.3% if your pet has a history of hypersensitivity to ciprofloxacin or any other component of the medication is a contraindication to its use. A history of hypersensitivity to other quinolones may also contraindicate the use of ciprofloxacin.