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Galliprant Tablets

Galliprant Tablets

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Galliprant® (grapiprant tablets) is a new class of anti-inflammatory that targets pain, so you can start targeted pain relief from the earliest diagnosed stages of canine OA. Give these dogs the relief they need and help keep them doing the things they love.

Primary Use

Prescription medication that controls pain and inflammation associated with osteoarthritis in dogs.

Key Benefits

  • Treats canine OA pain and inflammation
  • Easy to adminster with chicken-flavored tablet form that can be taken with or without food.
  • Galliprant is a first-in-class piprant; a non-COX-inhibiting prostaglandin receptor antagonist (PRA)
  • Galliprant does not inhibit the production of many housekeeping prostanoids that maintain homeostatic functions
  • It specifically blocks the EP4 receptor, the primary mediator of canine OA pain and inflammation

How It Works

Galliprant deploys a new, targeted approach to relieving canine osteoarthritis (OA) pain and inflammation. It does this by specifically targeting the EP4 receptor, helping to keep the GI, kidney and liver homeostatic functions maintained.


Galliprant is not for use in humans. Do not use in dogs younger than 9 months and less than 8 pounds, dogs used for breeding, or in pregnant or lactating dogs.

NADA 141-455


Active Ingredient



Dosage and Administration

Use the lowest effective dose for the shortest duration consistent withindividual response.

The dose of Galliprant (grapiprant tablets) is 0.9 mg/lb (2 mg/kg) once daily.

Galliprant tablets are scored and dosage should be calculated in half tablet increments. Dogs less than 8 lbs (3.6 kgs) cannot be accurately dosed.

View Galliprant package insert for more information.

Dosage Table

Weight in PoundsWeight in Kilograms20 mg tablet60 mg tablet100 mg tablet
30.1-4513.7-20.4 0.5 
45.1-7520.5-34 1 
75.1-15034.1-68  1
150.1-22068.1-100  2

Storage Directions

Store at or below 86° F (30° C). Keep out of reach of children and animals.


Galliprant should not be used in dogs that have a hypersensitivity to grapiprant.

Possible Side Effects

Vomiting, soft, mucoid stools, diarrhea and decreased appetite.


Galliprant® (grapiprant tablets) is a first-of-its-kind, non-steroidal anti-inflammatory (NSAID) that uses targeted action to treat canine osteoarthritis pain and inflammation. The convenient, flavored chewable tablet is safe to use daily. Your veterinarian may start treatment for your dog as early as 9 months of age and as soon as your dog is diagnosed with osteoarthritis to help keep your dog doing the things he loves.
Once osteoarthritis pain sets in, your dog is less likely to move and may put on a few extra pounds. This can lead to more stress on joints and even more inflammation and pain. Galliprant can help break the cycle by providing targeted osteoarthritis pain relief so your dog can continue doing the things he loves, like going on walks and playing fetch.
Your veterinarian will prescribe the proper dose for your dog; talk with your veterinarian if you have questions. Your dog should not use Galliprant if less than 8 pounds of body weight. Dogs that weigh more than 150 pounds may require more than one tablet.
Galliprant can be administered with or without food.
Galliprant is available as a once daily, flavored chewable tablet.
As osteoarthritis is a chronic disease, Galliprant may need to be given for an extended period of time. Ask your veterinarian what's right for your dog and periodically discuss your dog's ongoing response to treatment.
Yes! Galliprant is approved for daily use to provide targeted osteoarthritis pain relief so your dog can continue doing the things he loves, like going on walks and playing fetch. The most common side effects associated with Galliprant include vomiting, soft, mucoid stools, diarrhea, decreased appetite. You should contact your veterinarian if your dog's appetite decreases or stools become abnormal or if your dog experiences any other side effects.
Galliprant was used (safely) during the field studies with other concurrent therapies, including antibiotics, parasiticides, and vaccinations. Galliprant should not be given with other non-steroidal anti-inflammatory drugs (NSAIDs) or corticosteroids (for example, aspirin, caprofen, meloxicam and prednisone). The concomitant use of protein-bound drugs with Galliprant has not been studied. Commonly used protein-bound drugs include cardiac, anticonvulsant and behavioral medications. Talk with your veterinarian about any medications your dog is taking, or that you plan to give your dog.
It's important to tell your veterinarian about all medications that you are giving your dog or plan to give your dog, including those you can get without a prescription and any dietary supplements. Your veterinarian can help you determine whether adding a joint supplement is appropriate for your dog.
Galliprant contains pork liver as the flavoring agent. It is up to your veterinarian to determine the best course of treatment in a potentially allergic dog.
You should discuss any other conditions your dog has with your veterinarian to determine whether or not it is safe for your dog to take Galliprant.
Once you have a prescription from your veterinarian, you can purchase Galliprant directly from your veterinarian or through an authorized pet pharmacy. It is important to follow up with your veterinarian from time to time.

See the expiration date that has been provided on the prescription your dog receives. Ask your veterinarian if you have questions.

Galliprant (grapiprant tablets) is indicated for the control of pain and inflammation associated with osteoarthritis in dogs.

Not for use in humans. For use in dogs only. Keep out of reach of children and pets. Monitoring is recommended if used long term. Should not be used in dogs who are allergic to grapiprant or with other anti-inflammatory drugs. The safe use of Galliprant has not been studied in dogs younger than 9 months of age and less than 8 pounds (3.6 kg), dogs used for breeding, pregnant or lactating dogs, or dogs with heart disease. The most common adverse reactions were vomiting, diarrhea, decreased appetite and tiredness. See full safety information on the Galliprant label.

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