Galliprant Tablets
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Galliprant Tablets

Galliprant Tablets

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Galliprant (grapiprant tablets) is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. See package insert for complete product details.

Galliprant (grapiprant tablets) is a new, targeted approach to relieving canine osteoarthritis (OA) pain and inflammation. Its mode of action specifically targets the EP4 receptor, helping to keep the GI, kidney and liver homeostatic functions maintained.

Prescription Required


Galliprant®(grapiprant tablets) is a new class of anti-inflammatory that targets pain, so you can start targeted pain relief from the earliest diagnosed stages of canine OA. Give these dogs the relief they need and help keep them doing the things they love.

  • Galliprant is a first-in-class piprant; a non-COX-inhibiting prostaglandin receptor antagonist (PRA)
  • Galliprant does not inhibit the production of many housekeeping prostanoids that maintain homeostatic functions1
  • It specifically blocks the EP4 receptor, the primary mediator of canine OA pain and inflammation1

  • Galliprant tested at up to approximately 15X the labeled dose for 9 months in healthy dogs.2,3
  • Studied at up to approximately 15X the labeled 2 mg/kg dose for a 9-month duration in healthy dogs
  • No clinically significant changes in liver, kidney or coagulation parameters
  • No noticeable effects on food consumption, body weight, ECG, organ weight or hematology
  • In most situations, gastrointestinal disturbances were mild or slight and fairly infrequent
  • Neither treatment nor GI disturbance was associated with changes in appetite, appearance or demeanor of dogs
  • Suitable for dogs as young as 9 months of age

  • Galliprant treatment resulted in statistically significant improvements in pain interference and pain severity scores compared to placebo on days 7, 14, 21 and 28.4
  • Prospective, randomized, masked, placebo-controlled, 16-site study
  • Galliprant dosed at 2 mg/kg once daily for 28 days
  • 285 dogs enrolled
  • Dogs receiving Galliprant were 2 to 16.75 years old, weighing 9 to 131 pounds
  • Placebo tablet size and shape matched to Galliprant tablets
  • Validated owner assessment: Canine Brief Pain Inventory (CBPI)* on days 0, 7, 14, 21, 28
  • Veterinary assessment (total orthopedic scores) at screening and on days 14 and 28

  • Grapiprant represents a promising treatment modality for the pain and inflammation associated with OA in dogs.

    Mode of action targets canine OA pain and inflammation while reducing the impact on GI, kidney and liver homeostasis1,2
  • Suitable for dogs as young as 9 months of age
  • Proven safe in a 9-month safety study at up to approximately 15X the recommended therapeutic dose in healthy dogs2,3
  • Most dogs can be dosed with a whole or half tablet

  • Dose Weight in Pounds Weight in Kilograms 20 mg tablet 60 mg tablet 100 mg tablet
    0.9 mg/lb (2 mg/kg) once daily 8-15 3.6-6.8 0.5    
    0.9 mg/lb (2 mg/kg) once daily 15.1-30 6.9-13.6 1    
    0.9 mg/lb (2 mg/kg) once daily 30.1-45 13.7-20.4   0.5  
    0.9 mg/lb (2 mg/kg) once daily 45.1-75 20.5-34   1  
    0.9 mg/lb (2 mg/kg) once daily 75.1-150 34.1-68     1
    0.9 mg/lb (2 mg/kg) once daily 150.1-220 68.1-100     2


    45 Reviews
    87% (39)
    9% (4)
    2% (1)
    2% (1)
    0% (0)
    100% Recommend this product (45 of 45 responses)
    By Kerry
    July 6, 2018
    I have my dog back!
    My vet noticed my Husky seemed to be having hip problems when I boarded him for a couple days last summer. I thought he wasn't as active because of the summer heat. She prescribed Galliprant and a joint supplement. Within a week he was chasing tennis balls again and had lots of stamina on our daily walks. This medicine has done wonders with no negative side affects observed in a year of use.
    Merchant Response:Spectacular story Kerry. Stories like this are great!
    By Trent
    Springfield Missouri
    April 26, 2018
    Great product
    Galliprant has made a huge difference in my aging dog's mobility. Since she had been taking Galliprant she is much more active.

    Merchant Response:Glad Galliprant could help. You have one adorable dog Trent =)
    By Marcia
    September 27, 2018
    Excellent product, excellent service
    Appreciated the speed of this prescription from my request to delivery. Also the product is great too. Thank you!
    Merchant Response:We do our best! Glad you like the Galliprant.
    ProsContacted my vet and processed the request very quickly.
    By Y2vett
    September 8, 2018
    Miracle Worker
    This little magic pill really seems to be helping my dog. She would suffer from stiff joints and would limp on occasion. Since being prescribed the Gailliprant she has been 100%, no limp and she can once again enjoy her long morning walks.
    Merchant Response:Y2vett, We are ecstatic to hear that your dog has found relief with Gailliprant and is enjoying her long morning walks.
    By Jennifer
    Las Vegas, NV
    September 5, 2018
    Highly effective for my Labrador!
    I have an 8 year old Labrador with significant arthritis in his ankles. The arthritis started to present itself about 2 years, which was before Galliprant was released. Our morning walks had dwindled down to once or twice a week outings and he was always in noticeable discomfort. Rimadyl did nothing to help him. My vet recommended that I try Galliprant once it was released and it made an almost immediate difference. Within days he was walking around like nothing was bothering him. He’s been taking the medication for a year and a half, and we are back to walking every morning. It’s an expensive medication but I haven’t found anything else that comes close to the results we’ve gotten from Galliprant. And no side effects.
    ProsHighly effective. Started working almost immediately. No side effects.
    By Bob
    Mojave desert
    August 25, 2018
    Good results
    The medication is expensive but appears to be helping my almost 15 year old Pekinese remain active and relatively happy.
    ProsThe best price I could find online and in person
    ConsPrice still seems high
    By Mo
    August 18, 2018
    Great service
    Fast, easy and affordable service! We live in the sierras so receiving our dogs medication by mail is definitely a plus. The cost of our dogs prescription at our vet office was very costly. This pet pharmacy offered us a significant savings. They contacted our vet office immediately and we had our dogs prescription in less than 5 days. We will definitely be using this pet pharmacy regularly.
    Merchant Response:Mo, That's why we are here! Thank you for the kind words. We'll be here for you and your animals when you need us. Take care!
    By Mary K Perrine
    August 8, 2018
    I love this product
    By Becky
    Waco, TX
    August 3, 2018
    Galliprant is great
    Galliprant really helps my fur baby and his arthritis feel better. Entirely pets was was to order and the best price!
    By Dianne
    July 13, 2018
    Excellent service
    Always some to speak with on phone and is specific about any special instructions for prescriptions. Discounts always applied and shipping is very timely. I love this company!!!
    Merchant Response:Thank you for your kind words Dianne! Glad we are able to help!
    By Jana Chauncey
    July 12, 2018
    Wonderful Medication
    This medication has helped both of my dogs better than any other anti-inflammatory. They love the flavor as well.
    Merchant Response:Hi Jana, It's great to hear how well the Galliprant Tabs are working for your pups. Hope all is well!
    ProsGreat medication
    ConsIt is expensive
    By Patricia L Radtke-Pirko
    July 2, 2018
    Arthritis uin back legs
    My 14 year old dog does great with this products, Makes me happy to see her get up and down without having a hard time trying to get up.

    Merchant Response:Hello Patricia, thank you for your comment and we are happy to hear the Galliprant is working well for your dog!
    By Carol
    Vashon Island, WA
    June 3, 2018
    Good price, great service
    My vet prescribed Galliprant for my very old Newf awhile back; along with some other prescription drugs, Galliprant is making her last months more comfortable: she’s walking, slower and less and less far as time goes on, and still enjoying those little walks and her meals and, well, life. We take it a day at a time and appreciate each good day.

    Merchant Response:Carol, Glad to hear Galliprant is working for your newfoundland dog. She's beautiful.
    By Joan
    Naperville, IL
    May 31, 2018
    Amazing pain relief!
    We thought our old English bulldog was at the end of his time. He was in so much pain, he could not get outside to the bathroom. Since he started on Galliprant, he can not only go outside, but can climb the staircase to bed in the evening. We are so grateful for the extra time we have with him now.

    Merchant Response:Good for him. We a big fans of English Bulldogs here.
    ProsNo side effects we can see, only pain relief.
    ConsHard to get.
    By Tina
    Northeast PA
    May 31, 2018
    Good product
    I've had my almost 16 year old dog on this medication for almost a year. It has helped her, although I can still see her favor herself due to arthritis. I like that it is a safer medication for her organs and that it is a daily medication.
    By Laura
    Portland, OR
    April 29, 2018
    helped my 11 yo lab
    After a couple days of giving this to my 11 year old yellow lab, I noticed she was more willing to get up and move around and more interested in walks and play. She has an easier time getting up and down the stairs, and on and off the couch. I've definitely noticed an improvement, but I can't quite call it a miracle drug. We will keep giving this to her!
    Merchant Response:We do our best on pricing with Galliprant. We have a direct relationship and pass as much savings along as possible.
    Prosadminister once a day, our dog eats it along with her food every morning. a good alternative to NSAID options.
    By Pam
    April 20, 2018
    My dog has gotten her spunk back. She would limp after just a small amount of exercise. Now she is going on long walks and playing with her ball like she did before she had ACL surgery.
    By Adrienne
    San Jose, CA
    April 8, 2018
    Galliprant helps
    I don't know if it's Galliprant that keeps my 14-year old golden retriever going for 2 walks (slooooow ones) a day, but I am happy to keep giving it to him and love having him with me. I also started giving him Omega-3 pet soft gels recently, so that could be helping. My two cents' worth.
    By Susan
    Salem, Missouri
    March 25, 2018
    Wonderful product
    Galliprant has made a dramatic change in our 11 year old Irish Setter's life. She no longer shows any effects of arthritis. She runs in the field and wrestles with our younger dog like she's a pup again. The best part is that Galliprant doesn't affect the kidneys like other arthritis pain killers so she doesn't need frequent blood tests.
    By Carol
    Bedford, Va
    March 18, 2018
    Tried this on recommendation of my vet for 12 yo terrier with arthritis who won't give up jumping on and off bed. He's walking/jumping well with no apparent discomfort. Well tolerated. No side effects thus far. We switched because at his age we wanted less liver impact.
    ProsEasily taken in food Once a day dosing or can split and 1/2 dose twice a day
    By Teasha
    Palmdale, CA
    March 4, 2018
    Great Price, Great Medication
    This medication works to ease my dog's pain. The process of ordering this was painless as all the work to obtain the prescription from my veterinarian was done by entirely pet pharmacy. EPP kept me informed whenever there was a delay or when they received the prescription and when it was on the way to me. I appreciate the personal treatment I receive when ordering from EPP.
    By joan leahy
    March 1, 2018
    very good customer service!!!!! thank you!!!!
    By Richard Abood
    Culver City, CA
    February 15, 2018
    I have bought from you five times this item. Twice it was out of stock and another time it took you three days after I ordered it for you to ship it. I called on a Monday and they told me it would be shipped right away and it wasn't shipped till Wednesday. Not a very good track record.
    By Mike
    February 15, 2018
    Our Lab is over 11 years and had a lot of problems walking. Galliprant has helped tremendously. He was able to hunt pheasants this season without being in constant pain.
    By Carol
    Hemet, calif
    February 15, 2018
    They really help her out a lot.
    By Nanci
    Mountain View, Ca.
    January 26, 2018
    Great deal!
    Entirely Pets is a great place to get your rx items for your pets! They delivery so quickly you can't beat this!!
    By Richard
    Phoenix, AZ
    December 8, 2017
    Faster processing this time around.
    The initial presentation of the pain Rx, took weeks to get traction on. But, this is now a refill, that moved very quickly through the order process. Thank you.
    By DAVID
    December 8, 2017
    Merchant Response:Thank you for your feedback David and I am terribly sorry to hear the Galliprant doesn't sit well with your dog's GI tract! Was there another medication your vet could suggest trying?
    By Kelly
    Chicago, IL
    November 18, 2017
    awesome results
    Our dog experiences significant hip pain. As he has aged, it has really impacted his ability to walk and climb stairs. We began using this medication about three months ago. We give him half a pill a day. After a couple of days, we saw a huge change in his behavior. He is able to walk, run, and climb stairs much easier. It is almost like having a puppy back in the house.
    Merchant Response:Hi Kelly, we are so happy to hear the Galliprant really helps your dog feel young again and enables him to run around and play! We wish you all the best!
    By Lorinda
    November 3, 2017
    Pricey but worth it
    4 stars considered because of price. 5 stars on how my dog feels taking it! He has severe arthritis at age 9 and was taking an NSAID that was fine. Worried about long term use, I read about Galliprant being less harsh. He is doing as well if not better and I feel better that it could be less harmful long term. He cannot stand if not taking it. The time will still come too soon for him, but Galliprant has prolonged his quality of life and therefore mine too. He has siblings showing signs and I don't know how I will financially afford it, but emotionally I will find a way. It is worth it when I see him smile as he runs, yes runs, towards me.
    ProsIt works Reported to be less harmful long term I can put in his food and he takes it readily