Galliprant Tablets
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Galliprant Tablets

Galliprant Tablets

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Galliprant (grapiprant tablets) is indicated for the control of pain and inflammation associated with osteoarthritis in dogs. See package insert for complete product details.

Galliprant (grapiprant tablets) is a new, targeted approach to relieving canine osteoarthritis (OA) pain and inflammation. Its mode of action specifically targets the EP4 receptor, helping to keep the GI, kidney and liver homeostatic functions maintained.

Prescription Required


Galliprant®(grapiprant tablets) is a new class of anti-inflammatory that targets pain, so you can start targeted pain relief from the earliest diagnosed stages of canine OA. Give these dogs the relief they need and help keep them doing the things they love.

  • Galliprant is a first-in-class piprant; a non-COX-inhibiting prostaglandin receptor antagonist (PRA)
  • Galliprant does not inhibit the production of many housekeeping prostanoids that maintain homeostatic functions1
  • It specifically blocks the EP4 receptor, the primary mediator of canine OA pain and inflammation1

  • Galliprant tested at up to approximately 15X the labeled dose for 9 months in healthy dogs.2,3
  • Studied at up to approximately 15X the labeled 2 mg/kg dose for a 9-month duration in healthy dogs
  • No clinically significant changes in liver, kidney or coagulation parameters
  • No noticeable effects on food consumption, body weight, ECG, organ weight or hematology
  • In most situations, gastrointestinal disturbances were mild or slight and fairly infrequent
  • Neither treatment nor GI disturbance was associated with changes in appetite, appearance or demeanor of dogs
  • Suitable for dogs as young as 9 months of age

  • Galliprant treatment resulted in statistically significant improvements in pain interference and pain severity scores compared to placebo on days 7, 14, 21 and 28.4
  • Prospective, randomized, masked, placebo-controlled, 16-site study
  • Galliprant dosed at 2 mg/kg once daily for 28 days
  • 285 dogs enrolled
  • Dogs receiving Galliprant were 2 to 16.75 years old, weighing 9 to 131 pounds
  • Placebo tablet size and shape matched to Galliprant tablets
  • Validated owner assessment: Canine Brief Pain Inventory (CBPI)* on days 0, 7, 14, 21, 28
  • Veterinary assessment (total orthopedic scores) at screening and on days 14 and 28

  • Grapiprant represents a promising treatment modality for the pain and inflammation associated with OA in dogs.

    Mode of action targets canine OA pain and inflammation while reducing the impact on GI, kidney and liver homeostasis1,2
  • Suitable for dogs as young as 9 months of age
  • Proven safe in a 9-month safety study at up to approximately 15X the recommended therapeutic dose in healthy dogs2,3
  • Most dogs can be dosed with a whole or half tablet

  • Dose Weight in Pounds Weight in Kilograms 20 mg tablet 60 mg tablet 100 mg tablet
    0.9 mg/lb (2 mg/kg) once daily 8-15 3.6-6.8 0.5    
    0.9 mg/lb (2 mg/kg) once daily 15.1-30 6.9-13.6 1    
    0.9 mg/lb (2 mg/kg) once daily 30.1-45 13.7-20.4   0.5  
    0.9 mg/lb (2 mg/kg) once daily 45.1-75 20.5-34   1  
    0.9 mg/lb (2 mg/kg) once daily 75.1-150 34.1-68     1
    0.9 mg/lb (2 mg/kg) once daily 150.1-220 68.1-100     2


    30 Reviews
    83% (25)
    13% (4)
    3% (1)
    0% (0)
    0% (0)
    100% Recommend this product (30 of 30 responses)
    By Kerry
    July 6, 2018
    I have my dog back!
    My vet noticed my Husky seemed to be having hip problems when I boarded him for a couple days last summer. I thought he wasn't as active because of the summer heat. She prescribed Galliprant and a joint supplement. Within a week he was chasing tennis balls again and had lots of stamina on our daily walks. This medicine has done wonders with no negative side affects observed in a year of use.
    Merchant Response:Spectacular story Kerry. Stories like this are great!
    By Trent
    Springfield Missouri
    April 26, 2018
    Great product
    Galliprant has made a huge difference in my aging dog's mobility. Since she had been taking Galliprant she is much more active.

    Merchant Response:Glad Galliprant could help. You have one adorable dog Trent =)
    By Marcia
    September 27, 2018
    Excellent product, excellent service
    Appreciated the speed of this prescription from my request to delivery. Also the product is great too. Thank you!
    Merchant Response:We do our best! Glad you like the Galliprant.
    ProsContacted my vet and processed the request very quickly.
    By Y2vett
    September 8, 2018
    Miracle Worker
    This little magic pill really seems to be helping my dog. She would suffer from stiff joints and would limp on occasion. Since being prescribed the Gailliprant she has been 100%, no limp and she can once again enjoy her long morning walks.
    Merchant Response:Y2vett, We are ecstatic to hear that your dog has found relief with Gailliprant and is enjoying her long morning walks.
    By Jennifer
    Las Vegas, NV
    September 5, 2018
    Highly effective for my Labrador!
    I have an 8 year old Labrador with significant arthritis in his ankles. The arthritis started to present itself about 2 years, which was before Galliprant was released. Our morning walks had dwindled down to once or twice a week outings and he was always in noticeable discomfort. Rimadyl did nothing to help him. My vet recommended that I try Galliprant once it was released and it made an almost immediate difference. Within days he was walking around like nothing was bothering him. He’s been taking the medication for a year and a half, and we are back to walking every morning. It’s an expensive medication but I haven’t found anything else that comes close to the results we’ve gotten from Galliprant. And no side effects.
    ProsHighly effective. Started working almost immediately. No side effects.
    By Bob
    Mojave desert
    August 25, 2018
    Good results
    The medication is expensive but appears to be helping my almost 15 year old Pekinese remain active and relatively happy.
    ProsThe best price I could find online and in person
    ConsPrice still seems high
    By Mo
    August 18, 2018
    Great service
    Fast, easy and affordable service! We live in the sierras so receiving our dogs medication by mail is definitely a plus. The cost of our dogs prescription at our vet office was very costly. This pet pharmacy offered us a significant savings. They contacted our vet office immediately and we had our dogs prescription in less than 5 days. We will definitely be using this pet pharmacy regularly.
    Merchant Response:Mo, That's why we are here! Thank you for the kind words. We'll be here for you and your animals when you need us. Take care!
    By Mary K Perrine
    August 8, 2018
    I love this product
    By Becky
    Waco, TX
    August 3, 2018
    Galliprant is great
    Galliprant really helps my fur baby and his arthritis feel better. Entirely pets was was to order and the best price!
    By Dianne
    July 13, 2018
    Excellent service
    Always some to speak with on phone and is specific about any special instructions for prescriptions. Discounts always applied and shipping is very timely. I love this company!!!
    Merchant Response:Thank you for your kind words Dianne! Glad we are able to help!
    By Jana Chauncey
    July 12, 2018
    Wonderful Medication
    This medication has helped both of my dogs better than any other anti-inflammatory. They love the flavor as well.
    Merchant Response:Hi Jana, It's great to hear how well the Galliprant Tabs are working for your pups. Hope all is well!
    ProsGreat medication
    ConsIt is expensive
    By Patricia L Radtke-Pirko
    July 2, 2018
    Arthritis uin back legs
    My 14 year old dog does great with this products, Makes me happy to see her get up and down without having a hard time trying to get up.

    Merchant Response:Hello Patricia, thank you for your comment and we are happy to hear the Galliprant is working well for your dog!
    By Carol
    Vashon Island, WA
    June 3, 2018
    Good price, great service
    My vet prescribed Galliprant for my very old Newf awhile back; along with some other prescription drugs, Galliprant is making her last months more comfortable: she’s walking, slower and less and less far as time goes on, and still enjoying those little walks and her meals and, well, life. We take it a day at a time and appreciate each good day.

    Merchant Response:Carol, Glad to hear Galliprant is working for your newfoundland dog. She's beautiful.
    By Joan
    Naperville, IL
    May 31, 2018
    Amazing pain relief!
    We thought our old English bulldog was at the end of his time. He was in so much pain, he could not get outside to the bathroom. Since he started on Galliprant, he can not only go outside, but can climb the staircase to bed in the evening. We are so grateful for the extra time we have with him now.

    Merchant Response:Good for him. We a big fans of English Bulldogs here.
    ProsNo side effects we can see, only pain relief.
    ConsHard to get.
    By Tina
    Northeast PA
    May 31, 2018
    Good product
    I've had my almost 16 year old dog on this medication for almost a year. It has helped her, although I can still see her favor herself due to arthritis. I like that it is a safer medication for her organs and that it is a daily medication.
    By Laura
    Portland, OR
    April 29, 2018
    helped my 11 yo lab
    After a couple days of giving this to my 11 year old yellow lab, I noticed she was more willing to get up and move around and more interested in walks and play. She has an easier time getting up and down the stairs, and on and off the couch. I've definitely noticed an improvement, but I can't quite call it a miracle drug. We will keep giving this to her!
    Merchant Response:We do our best on pricing with Galliprant. We have a direct relationship and pass as much savings along as possible.
    Prosadminister once a day, our dog eats it along with her food every morning. a good alternative to NSAID options.
    By Nanci
    Mountain View, Ca.
    January 26, 2018
    Great deal!
    Entirely Pets is a great place to get your rx items for your pets! They delivery so quickly you can't beat this!!
    By Richard
    Phoenix, AZ
    December 8, 2017
    Faster processing this time around.
    The initial presentation of the pain Rx, took weeks to get traction on. But, this is now a refill, that moved very quickly through the order process. Thank you.
    By DAVID
    December 8, 2017
    Merchant Response:Thank you for your feedback David and I am terribly sorry to hear the Galliprant doesn't sit well with your dog's GI tract! Was there another medication your vet could suggest trying?
    By Kelly
    Chicago, IL
    November 18, 2017
    awesome results
    Our dog experiences significant hip pain. As he has aged, it has really impacted his ability to walk and climb stairs. We began using this medication about three months ago. We give him half a pill a day. After a couple of days, we saw a huge change in his behavior. He is able to walk, run, and climb stairs much easier. It is almost like having a puppy back in the house.
    Merchant Response:Hi Kelly, we are so happy to hear the Galliprant really helps your dog feel young again and enables him to run around and play! We wish you all the best!
    By Lorinda
    November 3, 2017
    Pricey but worth it
    4 stars considered because of price. 5 stars on how my dog feels taking it! He has severe arthritis at age 9 and was taking an NSAID that was fine. Worried about long term use, I read about Galliprant being less harsh. He is doing as well if not better and I feel better that it could be less harmful long term. He cannot stand if not taking it. The time will still come too soon for him, but Galliprant has prolonged his quality of life and therefore mine too. He has siblings showing signs and I don't know how I will financially afford it, but emotionally I will find a way. It is worth it when I see him smile as he runs, yes runs, towards me.
    ProsIt works Reported to be less harmful long term I can put in his food and he takes it readily
    By regina
    alameda, ca
    October 25, 2017
    helped tremendously
    we have a 15 year old lab/terrier mix with awful arthritis in her hips. Galliprant has made a huge difference for her,along with Gapapentin and Tramadal. She is still a happy girl, she has been on the Galliprant for about 3 months. Only downside is loose stools.
    Prospain relief, quality of life.
    Consloose stools
    By Donna
    Minneapolis, Minnesota
    October 22, 2017
    Galliprant tabs
    My vet recommended this, even though they do not carry it. Entirely Pets had the best price, so I contacted them, and they contacted my vet for the prescription. It all went well, and my little dog seems to be doing fine with this instead of the one that she had been taking and that my vet said was more harmful to her organs.
    By Betty
    October 19, 2017
    excellent pain relief!
    More effective than the other Rx drugs for pain/inflammation. My cute little pom prances around once again when on Galliprant. I noticed less digestive issues, as nausea, with this drug. Highly recommended!
    Merchant Response:Hello Betty, thank you so much for your feedback and we're so happy to hear the Galliprant helps put the pep back in the step of your little Pomeranian!
    Prosvery effective pain management.
    Consoccasional nausea after being on the Rx for > 3 days straight. Easily resolved by skippng one day after 3 continuous days on Galliprant - my vet fully agrees with this "fix".
    By Bob
    Olympia, WA
    October 15, 2017
    A true Blessing
    Galliprant was recommended from my vet after my dog suffered terrible side affects from another medication. My dog was constantly limping due to arthritis and therefore had been miserable. Our ten year old Maggie loved to play fetch, hike and play until her arthritis prevented her from doing anything. After giving her Galliprant, it was like night and day. After a few days the limp was gone and she began getting back to her normal self. I can't say enough about this medication. I haven't noticed any side effects and will continue giving her Galliprant for life.

    Merchant Response:Thank you for the feedback Bob, we truly love the photos of Molly and are so happy to hear the Galliprant has her feeling good again and able to partake in all her favorite activities with you again!
    By Raney
    Albuquerque, New Mexico
    September 2, 2017
    Pleased new customer
    After a pump was put on this expense of anti-inflammatory from the vets office we decided to shop around. Your pricing was more than fair and we were very happy with the communication. It took a while to run it through our vet but I'm sure it will be quick in the future now for refills . Very pleased and will be using you all again. Raney, Rob, barney, polkadot and Jaina in Albuquerque New Mexico
    Merchant Response:Hello Raney, thank you so much for your feedback and we look forward to continuing to help you save money on your dog's medications!
    By Molly Jo
    NW Ohio
    July 14, 2017
    Great Price Same item
    I purchased a three months supply of Galliprant for my 11 yr old poodles arthritis and the total cost was what a one month supply cost from my vet. For exact SAME product! Highly recommended!
    Prossame item less cost, fast shipping
    Consnone so far
    By Cynthia Sheppard
    Cottonwood, CA
    June 23, 2017
    Galliprant Tabs
    Vet recommended this new medicine for my dog, he didn't carry it and so I went on a search for it and found it here and at a reasonable price. Excellent delivery time and always available to help me if needed. Wouldn't go anywhere else
    By Boston Bob
    June 1, 2017
    Galliprant Great, Service less so
    Galliprant has improved my 14 yo Lab's life immensely. She was having trouble with stairs, struggling to get up on hardwood floors, and generally not very happy. I'm now 3 weeks in and she's almost back to her bouncy self. Ginger has a sensitive stomach so my vet was reluctant to use more common NSAIDs. She has had no negative gastro impacts from Galliprant. It's not cheap, but I do recommend it in the right situations. I would give Galliprant 5 stars.
    By Tyson
    San Juan Capistrano, CA
    April 28, 2017
    Works like it is supposed to
    I received the item in a timely manner. It also came with a free gift which was very nice. The medication is the right one, and works just like it is supposed to.
    Merchant Response:Thank you for your feedback Tyson and we are so happy to hear the Galliprant is helping your dog and hope you enjoyed the gift :)