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Galliprant Tablets

Galliprant Tablets

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Get on up with Galliprant® (grapiprant tablets) and get down with reducing your dog's osteoarthritis pain. Galliprant is the easy-to-give daily medication that can be used at the earliest signs of osteoarthritis in dogs. It’s a first-of-its-kind non-steroidal anti-inflammatory (NSAID) that uses targeted action to treat canine osteoarthritis pain and inflammation.

Canine osteoarthritis is the most common cause of chronic pain in dogs, and it doesn't just occur in older, heavy dogs. It's a painful disease that causes inflammation and swelling in a dog's joints. Although there's no cure for canine osteoarthritis, recognizing the possible signs helps you treat your dog's pain as early as possible. Talk to your veterinarian today to learn more about canine osteoarthritis and how Galliprant may help your canine friend stay active.

Prescription Required


Galliprant®(grapiprant tablets) is a new class of anti-inflammatory that targets pain, so you can start targeted pain relief from the earliest diagnosed stages of canine OA. Give these dogs the relief they need and help keep them doing the things they love.

  • Galliprant is a first-in-class piprant; a non-COX-inhibiting prostaglandin receptor antagonist (PRA)
  • Galliprant does not inhibit the production of many housekeeping prostanoids that maintain homeostatic functions1
  • It specifically blocks the EP4 receptor, the primary mediator of canine OA pain and inflammation1

  • Galliprant tested at up to approximately 15X the labeled dose for 9 months in healthy dogs.2,3
  • Studied at up to approximately 15X the labeled 2 mg/kg dose for a 9-month duration in healthy dogs
  • No clinically significant changes in liver, kidney or coagulation parameters
  • No noticeable effects on food consumption, body weight, ECG, organ weight or hematology
  • In most situations, gastrointestinal disturbances were mild or slight and fairly infrequent
  • Neither treatment nor GI disturbance was associated with changes in appetite, appearance or demeanor of dogs
  • Suitable for dogs as young as 9 months of age

  • Galliprant treatment resulted in statistically significant improvements in pain interference and pain severity scores compared to placebo on days 7, 14, 21 and 28.4
  • Prospective, randomized, masked, placebo-controlled, 16-site study
  • Galliprant dosed at 2 mg/kg once daily for 28 days
  • 285 dogs enrolled
  • Dogs receiving Galliprant were 2 to 16.75 years old, weighing 9 to 131 pounds
  • Placebo tablet size and shape matched to Galliprant tablets
  • Validated owner assessment: Canine Brief Pain Inventory (CBPI)* on days 0, 7, 14, 21, 28
  • Veterinary assessment (total orthopedic scores) at screening and on days 14 and 28

  • Grapiprant represents a promising treatment modality for the pain and inflammation associated with OA in dogs.

    Mode of action targets canine OA pain and inflammation while reducing the impact on GI, kidney and liver homeostasis1,2
  • Suitable for dogs as young as 9 months of age
  • Proven safe in a 9-month safety study at up to approximately 15X the recommended therapeutic dose in healthy dogs2,3
  • Most dogs can be dosed with a whole or half tablet

  • Dose Weight in Pounds Weight in Kilograms 20 mg tablet 60 mg tablet 100 mg tablet
    0.9 mg/lb (2 mg/kg) once daily 8-15 3.6-6.8 0.5    
    0.9 mg/lb (2 mg/kg) once daily 15.1-30 6.9-13.6 1    
    0.9 mg/lb (2 mg/kg) once daily 30.1-45 13.7-20.4   0.5  
    0.9 mg/lb (2 mg/kg) once daily 45.1-75 20.5-34   1  
    0.9 mg/lb (2 mg/kg) once daily 75.1-150 34.1-68     1
    0.9 mg/lb (2 mg/kg) once daily 150.1-220 68.1-100     2


    Review Summary
    54 Reviews
    87% (47)
    9% (5)
    2% (1)
    2% (1)
    0% (0)
    100% Recommend this product (54 of 54 responses)
    By Cliff L.
    Madison, Mississippi
    A Miracle Drug for dog joints
    August 3, 2019
    Within 20 minutes of giving Cait, a 13 year old Border Collie, her first pill, she started being perky, walking without waddling, and best of all, had her old smile back and eyes full of joy! I had no real knowledge of how bad her pain had become until I saw the happy look on her face, again. And interest in things returned, a wagging tail is regular now!

    I tried the 30 day supply because I didn't want to pay the price of a larger bottle until I knew if it worked or not. So now I will buy the big bottle so that I won't miss a day of giving her pain freedom.

    The instructions which include results of the testing phase of this medicine said that there were few adverse reactions and no deaths of voluntary test subjects, and I have watched out for symptoms for two weeks now, and have not seen any adverse reaction. I heartily recommend this dog-only drug!
    ProsWalks normally again after two years of decreasing abilities. Keeps the pain away all day and until after bed time, resulting in her being able to do things she hasn't been able to do for a long time, and she shows all the signs of happiness to be alive! Easy to give. Flavored so she will want to chew it up before swallowing
    ConsNo cons.
    By Kerry
    I have my dog back!
    July 6, 2018
    My vet noticed my Husky seemed to be having hip problems when I boarded him for a couple days last summer. I thought he wasn't as active because of the summer heat. She prescribed Galliprant and a joint supplement. Within a week he was chasing tennis balls again and had lots of stamina on our daily walks. This medicine has done wonders with no negative side affects observed in a year of use.
    Merchant Response:Spectacular story Kerry. Stories like this are great!
    By Trent
    Springfield Missouri
    Great product
    April 26, 2018
    Galliprant has made a huge difference in my aging dog's mobility. Since she had been taking Galliprant she is much more active.

    Merchant Response:Glad Galliprant could help. You have one adorable dog Trent =)
    By Monica
    Southern California
    Great Arthritis Medicine For Dogs
    November 20, 2019
    This medicine was prescribed to us by our vet. Our senior dog (15 years old) has responded well to them, however, since our dog doesn't talk, it is hard to know what he thinks and what pain he is still feeling. I do notice he can still hop up in excitement when I get his food ready. The pills are beef flavored and I have no problem giving it to him without a treat. Highly recommend to others with dogs with arthritis issues.
    Merchant Response:Monica, we wish our dogs could talk. Galliprant Tabs are great. Thanks for your order.
    ProsBeef flavored pill.
    By Mtndog
    August 11, 2019
    Really good products
    ProsMy older Bernese loves these
    ConsPricey but effective
    By Danny
    Apollo Beach, FL
    Miracle drug
    July 12, 2019
    My yellow lab is turning 11 this month and had slowed down considerably a few months ago. He had difficulty getting up after laying on his bed for a while and could barely walk up 3 steps from the garage into the house. When we tried galliprant we saw immediate results. Within 2 days, he was energetic and acting like a young pup again. I'm so glad we tried this drug and will continue to use it.
    By Phil
    Lovettsville, VA
    Good price for the volume
    March 28, 2019
    Very good price for 90 tablets. Transfer of prescription was smooth and easy. Shipping was fast.
    By Monica
    West Hills, CA
    January 6, 2019
    No side effects so far and some improvement
    By M T.
    Galliprant helps my dog's arthritis pain!
    January 5, 2019
    My lab is only 8 years old and suffers terribly from arthritis. Galliprant is the only thing I could find that doesn't make him sick when he takes it and it alleviates his pain! The pricing at EntirelyPets is better than anywhere I have found for this medication including Costco! Thanks, EntirelyPets!
    By Gloria
    My furry kid is like a puppy again
    December 29, 2018
    Our 15 year old Shih-Tzu had problems getting up on all fours. Poor pup could hardly move with pain. After a couple days on Galliprant he came running into the room to greet us. He has been on the drug about a year now and he continues to benefit from it. I can’t imagine how his arthritis would do without it.
    By Caron
    Indian Wells, CA
    November 11, 2018
    Good price and fast shipping
    By Marcia
    Excellent product, excellent service
    September 27, 2018
    Appreciated the speed of this prescription from my request to delivery. Also the product is great too. Thank you!
    Merchant Response:We do our best! Glad you like the Galliprant.
    ProsContacted my vet and processed the request very quickly.
    By Y2vett
    Miracle Worker
    September 8, 2018
    This little magic pill really seems to be helping my dog. She would suffer from stiff joints and would limp on occasion. Since being prescribed the Gailliprant she has been 100%, no limp and she can once again enjoy her long morning walks.
    Merchant Response:Y2vett, We are ecstatic to hear that your dog has found relief with Gailliprant and is enjoying her long morning walks.
    By Jennifer
    Las Vegas, NV
    Highly effective for my Labrador!
    September 5, 2018
    I have an 8 year old Labrador with significant arthritis in his ankles. The arthritis started to present itself about 2 years, which was before Galliprant was released. Our morning walks had dwindled down to once or twice a week outings and he was always in noticeable discomfort. Rimadyl did nothing to help him. My vet recommended that I try Galliprant once it was released and it made an almost immediate difference. Within days he was walking around like nothing was bothering him. He’s been taking the medication for a year and a half, and we are back to walking every morning. It’s an expensive medication but I haven’t found anything else that comes close to the results we’ve gotten from Galliprant. And no side effects.
    ProsHighly effective. Started working almost immediately. No side effects.
    By Bob
    Mojave desert
    Good results
    August 25, 2018
    The medication is expensive but appears to be helping my almost 15 year old Pekinese remain active and relatively happy.
    ProsThe best price I could find online and in person
    ConsPrice still seems high
    By Mo
    Great service
    August 18, 2018
    Fast, easy and affordable service! We live in the sierras so receiving our dogs medication by mail is definitely a plus. The cost of our dogs prescription at our vet office was very costly. This pet pharmacy offered us a significant savings. They contacted our vet office immediately and we had our dogs prescription in less than 5 days. We will definitely be using this pet pharmacy regularly.
    Merchant Response:Mo, That's why we are here! Thank you for the kind words. We'll be here for you and your animals when you need us. Take care!
    By Mary P.
    August 8, 2018
    I love this product
    By Becky
    Waco, TX
    Galliprant is great
    August 3, 2018
    Galliprant really helps my fur baby and his arthritis feel better. Entirely pets was was to order and the best price!
    By Dianne
    Excellent service
    July 13, 2018
    Always some to speak with on phone and is specific about any special instructions for prescriptions. Discounts always applied and shipping is very timely. I love this company!!!
    Merchant Response:Thank you for your kind words Dianne! Glad we are able to help!
    By Jana C.
    Wonderful Medication
    July 12, 2018
    This medication has helped both of my dogs better than any other anti-inflammatory. They love the flavor as well.
    Merchant Response:Hi Jana, It's great to hear how well the Galliprant Tabs are working for your pups. Hope all is well!
    ProsGreat medication
    ConsIt is expensive
    By Patricia R.
    Arthritis uin back legs
    July 2, 2018
    My 14 year old dog does great with this products,
    Makes me happy to see her get up and down without having a hard time trying to get up.

    Merchant Response:Hello Patricia, thank you for your comment and we are happy to hear the Galliprant is working well for your dog!
    By Carol
    Vashon Island, WA
    Good price, great service
    June 3, 2018
    My vet prescribed Galliprant for my very old Newf awhile back; along with some other prescription drugs, Galliprant is making her last months more comfortable: she’s walking, slower and less and less far as time goes on, and still enjoying those little walks and her meals and, well, life. We take it a day at a time and appreciate each good day.

    Merchant Response:Carol, Glad to hear Galliprant is working for your newfoundland dog. She's beautiful.
    By Joan
    Naperville, IL
    Amazing pain relief!
    May 31, 2018
    We thought our old English bulldog was at the end of his time. He was in so much pain, he could not get outside to the bathroom. Since he started on Galliprant, he can not only go outside, but can climb the staircase to bed in the evening. We are so grateful for the extra time we have with him now.

    Merchant Response:Good for him. We a big fans of English Bulldogs here.
    ProsNo side effects we can see, only pain relief.
    ConsHard to get.
    By Tina
    Northeast PA
    Good product
    May 31, 2018
    I've had my almost 16 year old dog on this medication for almost a year. It has helped her, although I can still see her favor herself due to arthritis. I like that it is a safer medication for her organs and that it is a daily medication.
    By Laura
    Portland, OR
    helped my 11 yo lab
    April 29, 2018
    After a couple days of giving this to my 11 year old yellow lab, I noticed she was more willing to get up and move around and more interested in walks and play. She has an easier time getting up and down the stairs, and on and off the couch. I've definitely noticed an improvement, but I can't quite call it a miracle drug. We will keep giving this to her!
    Merchant Response:We do our best on pricing with Galliprant. We have a direct relationship and pass as much savings along as possible.
    Prosadminister once a day, our dog eats it along with her food every morning. a good alternative to NSAID options.
    By Pam
    April 20, 2018
    My dog has gotten her spunk back. She would limp after just a small amount of exercise. Now she is going on long walks and playing with her ball like she did before she had ACL surgery.
    By Adrienne
    San Jose, CA
    Galliprant helps
    April 8, 2018
    I don't know if it's Galliprant that keeps my 14-year old golden retriever going for 2 walks (slooooow ones) a day, but I am happy to keep giving it to him and love having him with me. I also started giving him Omega-3 pet soft gels recently, so that could be helping. My two cents' worth.
    By Susan
    Salem, Missouri
    Wonderful product
    March 25, 2018
    Galliprant has made a dramatic change in our 11 year old Irish Setter's life. She no longer shows any effects of arthritis. She runs in the field and wrestles with our younger dog like she's a pup again. The best part is that Galliprant doesn't affect the kidneys like other arthritis pain killers so she doesn't need frequent blood tests.
    By Carol
    Bedford, Va
    March 18, 2018
    Tried this on recommendation of my vet for 12 yo terrier with arthritis who won't give up jumping on and off bed.
    He's walking/jumping well with no apparent discomfort. Well tolerated. No side effects thus far.
    We switched because at his age we wanted less liver impact.
    ProsEasily taken in food Once a day dosing or can split and 1/2 dose twice a day
    By Teasha
    Palmdale, CA
    Great Price, Great Medication
    March 4, 2018
    This medication works to ease my dog's pain. The process of ordering this was painless as all the work to obtain the prescription from my veterinarian was done by entirely pet pharmacy. EPP kept me informed whenever there was a delay or when they received the prescription and when it was on the way to me. I appreciate the personal treatment I receive when ordering from EPP.