Carprovet Flavored Tablets (compares to Rimadyl) are used for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs. Carprovet Flavored Tablets contain carprofen, a non-steroidal anti-inflammatory drug (NSAID).
The recommended dosage for oral administration to dogs is 1 mg/lb of body weight twice daily. Carprovet Flavored Tablets are scored, and dosage should be calculated in half-tablet increments. Tablets can be halved by placing the tablet on a hard surface and pressing down on both sides of the score. Carprovet Flavored Tablets are palatable and willingly consumed by most dogs when offered by the owner. Therefore, they may be fed by hand or placed on food. Care should be taken to ensure that the dog consumes the complete dose.
Precautions: Carprovet should not be used in dogs exhibiting previous hypersensitivity to carprofen.
As a class, cyclooxygenase inhibitory NSAIDs may be associated with gastrointestinal and renal toxicity. Effects may result from decreased prostaglandin production and inhibition of the enzyme cyclooxygenase which is responsible for the formation of prostaglandins from arachidonic acid. When NSAIDs inhibit prostaglandins that cause inflammation, they may also inhibit those prostaglandins which maintain normal homeostatic function. These anti-prostaglandin effects may result in clinically significant disease in patients with the underlying or pre-existing disease more often than in healthy patients. NSAID therapy could unmask occult disease which has previously been undiagnosed due to the absence of apparent clinical signs. Patients with the underlying renal disease, for example, may experience exacerbation or decompensation of their renal disease while on NSAID therapy.
Carprofen is an NSAID, and as with others in that class, adverse reactions may occur with its use. The most frequently reported effects have been gastrointestinal signs. Events involving suspected renal, hematologic, neurologic, dermatologic, and hepatic effects have also been reported. Patients at greatest risk for renal toxicity are those that are dehydrated, on concomitant diuretic therapy, or those with renal, cardiovascular, and hepatic dysfunction. Since many NSAIDs possess the potential to induce gastrointestinal ulceration, concomitant use of Carprofen with other anti-inflammatory drugs, such as corticosteroids and NSAIDs, should be avoided or very closely monitored. Sensitivity to drug-associated adverse reactions varies with the individual patient. For example, Carprofen treatment was not associated with renal toxicity or gastrointestinal ulceration in well-controlled safety studies of up to 10 times the dose in dogs.
Carprofen is not recommended for use in dogs with bleeding disorders (e.g., Von Willebrand's disease), as safety has not been established in dogs with these disorders. The safe use of Carprofen in pregnant dogs, dogs used for breeding purposes, or in lactating bitches has not been established. Studies to determine the activity of Carprofen when administered concomitantly with other protein-bound drugs have not been conducted. Drug compatibility should be monitored closely in patients requiring additional therapy.
Due to the palatable nature of Carprovet Flavored Tablets, store out of reach of dogs in a secured location. Severe adverse reactions may occur if large quantities of tablets are ingested.
Adverse Reactions: May include decreased appetite, vomiting, diarrhea, dark or tarry stools, increased water consumption, increased urination, pale gums due to anemia, yellowing of gums, skin or white of the eye due to jaundice, lethargy, incoordination, seizure, or behavioral changes. Serious adverse reactions associated with this drug class can occur without warning and in rare situations result in death. Owners should be advised to discontinue Carprofen therapy and contact their veterinarian immediately if signs of intolerance are observed. The vast majority of patients with drug related adverse reactions have recovered when the signs are recognized, the drug is withdrawn, and veterinary care, if appropriate, is initiated. Owners should be advised of the importance of periodic follow-up for all dogs during administration of any NSAID.
For use in dogs only. Do not use in cats.
Storage: Store at controlled room temperature 15°C-30°C (59°F-86°F).
What is Carprovet?
Carprovet is a non-steroidal anti-inflammatory drug (NSAID) that is used to reduce pain and in inflammation (soreness) due to osteoarthritis and pain following surgery in dogs. Carprovet is a prescription drug for dogs. It is available as a tablet and is given to dogs by mouth.
Osteoarthritis (OA) is a painful condition caused by “wear and tear” of cartilage and other parts of the joints that may result in the following changes or signs in your dog:
To control surgical pain (e.g., for surgeries such as spays, ear procedures or orthopedic repairs) your veterinarian may administer Carprovet before the procedure and recommend that your dog be treated for several days after going home.
What kind of results can I expect when my dog is on Carprovet?
While Carprovet is not a cure for osteoarthritis, it can relieve the pain and inflammation of OA and improve your dog's mobility.
Who should not take Carprovet?
Your dog should not be given Carprovet if he/she:
Carprovet should be given to dogs only.
Cats should not be given Carprovet. Call your veterinarian immediately if your cat receives Carprovet. People should not take Carprovet. Keep Carprovet and all medicines out of reach of children. Call your physician immediately if you accidentally take Carprovet.
How to give Carprovet to your dog.
Carprovet should be given according to your veterinarian's instructions. Your veterinarian will tell you what amount of Carprovet is right for your dog and for how long it should be given. Carprovet should be given by mouth and may be given with or without food.
What to tell/ask your veterinarian before giving Carprovet.
Talk to your veterinarian about:
Tell your veterinarian if your dog has ever had the following medical problems:
Tell your veterinarian about:
Tell your veterinarian if your dog is:
What are the possible side effects that may occur in my dog during Carprovet therapy?
Carprovet, like other drugs, may cause some side effects. Serious but rare side effects have been reported in dogs taking NSAIDs, including Carprovet. Serious side effects can occur with or without warning and in rare situations result in death.
The most common NSAID-related side effects generally involve the stomach (such as bleeding ulcers), and liver or kidney problems. Look for the following side effects that can indicate your dog may be having a problem with Carprovet or may have another medical problem:
It is important to stop therapy and contact your veterinarian immediately if you think your dog has a medical problem or side effect from Carprovet therapy. If you have additional questions about possible side effects, talk to your veterinarian.
Can Carprovet be given with other medicines?
Carprovet should not be given with other NSAIDs (for example, aspirin, deracoxib, etodolac, firocoxib, meloxicam, tepoxalin) or steroids (for example, cortisone, dexamethasone, prednisone, triamcinolone).
Tell your veterinarian about all medicines you have given your dog in the past, and any medicines that you are planning to give with Carprovet. This should include other medicines that you can get without a prescription. Your veterinarian may want to check that all of your dog's medicines can be given together.
What do I do in case my dog eats more than the prescribed amount of Carprovet?
Contact your veterinarian immediately if your dog eats more than the prescribed amount of Carprovet.