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Rilexine (cephalexin)

Rilexine (cephalexin)

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Rilexine is a chewable tablet for the treatment of pyoderma skin disease in dogs. It also treats bacterial infections of the skin and urinary tract infections. It is FDA-approved and easier to administer than a capsule. Rilexine for dogs has 3 sizes of tablets, making it easier to give your dog the exact dose and prevent side effects associated with inaccurate dosing.

Rilexine Uses

  • Rilexine is used for the treatment of secondary superficial bacteria pyoderma in dogs caused by susceptible strains of Staphylococcus pseudintermedius.
  • It treats cutaneous infections in dogs, including skin fold pyoderma impetigo, folliculitis, furunculosis, cellulitis and urinary tract infections.

Key Benefits

  • Effectively treats pyoderma in dogs
  • Treats urinary tracts infections and bacterial infections of the skin
  • Comes in a tasty liver-flavored chewable tablet
  • Scored tablets for easy dosing
  • Available in 150 mg, 300 mg, and 600 mg

How It Works

Rilexine treats superficial bacterial pyoderma, a bacterial infection on the skin commonly found in dogs more so than cats. Symptoms include lesions, itchiness, and pus-filled swelling on the skin. In some cases, pyoderma can cause hair loss. Rilexine works by inhibiting the nucleopeptide synthesis of the bacterial wall, thus leading to the destruction of bacteria. Rilexine treats urinary tract infections and bacterial infections of the skin like skin fold pyoderma impetigo, folliculitis, furunculosis and cellulitis.


Keep out of reach of children. For Dogs Only. Do not use for humans. People with sensitivities to antimicrobials like penicillin should avoid handling.

NADA 141-326


Active Ingredient


ProductCephalexin Amount
Rilexine 150 mg150 mg
Rilexine 300 mg300 mg
Rilexine 600 mg600 mg


Dosage and Administration

Give this medication exactly as directed by your veterinarian. Rilexine can be given with or without food. The recommended dose of Rilexine (cephalexin) tablets is 22 mg/kg (10 mg/lb) of body weight twice daily for 28 days.

Quick Tips

  • Always consult with your veterinarian about the appropriate dosage for your dog.
  • Tablets are chewable and scored for easy dosing.
  • Do not give to dogs with a known allergy to cephalexin or penicillin.

Dosage Table

DogsAll WeightsThe recommended dose is 22 mg/kg (10 mg/lb) of body weight twice daily for 28 days.
*Consult your veterinarian for appropriate dosing

Storage Directions

Store capsules at room temperature away from moisture or heat.

Possible Side Effects

Diarrhea and rarely antibiotic-associated colitis, nausea and vomiting, abdominal discomfort, headache allergic reactions including rashes, pruritus, urticaria, serum sickness-like reactions with rashes, fever and arthralgia, and anaphylaxis; erythema multiforme, toxic epidermal necrolysis reported disturbances in liver enzymes, transient hepatitis and cholestatic jaundice other side-effects reported include eosinophilia and blood disorders (including thrombocytopenia, leucopenia, agranulocytosis, aplastic anaemia and haemolytic anaemia) reversible interstitial nephritis, hyperactivity, nervousness, sleep disturbances, confusion, hypertonia, and dizziness. However, at the levels associated with casual exposure, these are unlikely in normal use.


Keep out of reach of children. Do not handle or use extreme caution and proper precautions when handling this product if you know you are sensitized to it or are allergic to cephalexin, other cephalosporins, penicillin, or any other beta-lactam antibiotic or similar related medication.

If you are unsure of a possible sensitivity please contact your doctor or pharmacist. Handle this product in a manner that enables you to avoid any exposure, taking all recommended precautions. Wash hand after use. If you develop symptoms following exposure such as skin rash you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty breathing are more serious symptoms and require urgent medical attention.

Give the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and give the next regularly scheduled dose. Do not give a double dose unless otherwise directed by your veterinarian.
Seek emergency veterinary medical treatment.

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