Proin for Dogs | 25, 50, 75 mg | Free Shipping | EntirelyPets Rx
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Proin Chewable Tablets

Proin Chewable Tablets

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Recurring Saings in EprxAUTOSHIP & SAVE[Details]
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  • Description
  • Ingredients
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  • FAQ
  • Reviews


Shipping Restrictions

Unable to ship to the following states:

  • Arkansas, Illinois, Iowa, Louisiana, Oregon & West Virginia


Proin for dogs (phenylpropanolamine hydrochloride) is an FDA-Approved effective medication for managing and treating canine urinary incontinence. It is comes in a liver-flavored chewable tablet that makes for easy administration.

Proin Use

For the control of urinary incontinence due to urethral sphincter hypotonus in dogs

Animals Treated


Key Benefits

  • Is a supplement for urinary incontinence in dogs
  • Ensures sustained phenylpropanolamine levels in the bloodstream and may help reduce the conditions often associated with high levels of phenylpropanolamine such as decreased appetite, changes in heart rate, increased blood pressure, hyperexcitability
  • Palatable liver flavor

How It Works

Proin contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the bladder sphincter muscle, which helps to control urine leakage.

NADA #141-324


Active Ingredient

Phenylpropanolamine hydrochloride


Dosage and Administration

The total recommended dosage for oral administration is 2 mg/kg (0.91 mg/lb) of body weight twice daily. Proin is scored and dosage should be calculated in half-tablet increments. Give Proin exactly as directed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Proin at room temperature away from moisture and heat. Keep this medication away from children and pets.

View Proin drug facts sheet.

Quick Tips

  • The medication may be given with food.
  • Proin liver flavored chewable tablets are available by prescription for use in dogs to treat urinary incontinence.
  • Proin may cause restlessness, irritability, or loss of appetite.
  • Tell your veterinarian about any other medication you may be giving your pet.

Dosage Table

All weights2 mg/kg (0.91 mg/lb) of body weight twice daily

Storage Directions

Store at controlled room temperature 20-25°C (68-77°F), excursions permitted between 15-40°C (59-104°F) Keep out of reach of children and pets.


Proin may cause increased thirst. Make sure to provide ample fresh water. Don't give Proin with ephedrine or epinephrine, and don't give it within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar.


Not for human use. Keep out of reach of children. Consult a physician in case of accidental ingestion by humans./p>

Possible Side Effects

Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.


Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.
Seek emergency veterinary medical treatment. Symptoms of overdose may include increased blood pressure, increased heart rate, seizures or coma.
Do not give Proin with ephedrine or epinephrine and do not give within 2 weeks of using an MAOI such as selegiline or Preventic Collar.
Before giving Proin, tell your veterinarian if your pet is being given digoxin, NSAIDs such as aspirin or Rimadyl, tricyclic antidepressants such as clomipramine, and beta-blockers such as atenolol, or any other prescription or over the counter medications.
Tell your veterinarian if your pet has ever had an allergic reaction to this medication. Tell your veterinarian if your pet has glaucoma, hyperthyroid disease, diabetes, heart problems or high blood pressure. Tell your veterinarian if your pet is pregnant or lactating.


Review Summary
25 Reviews
84% (21)
16% (4)
0% (0)
0% (0)
0% (0)
100% Recommend this product (25 of 25 responses)
By Kap
New Jersey
February 5, 2021
Works great - fast shipping
Excellent price
By Nancy s.
St. Louis mo
Excellent service and good price
December 22, 2020
Thanks for answering my questions Staff well trained
By Wanda S.
Great price
October 21, 2020
Medicine works well. Best price I have found. Speedy delivery
By Anonymous
great product
September 20, 2020
Our female pointer was having UTI problems until the vet recommended Proin. Since we started using Proin, she hasn't had a single UTI !!
great price, slow delivery
August 6, 2020
price is great, but the process of getting a script to fulfill the order caused a major delay...
By Brent
Spring, TX
Good price. Good Value
May 22, 2020
This is a good price and value for Proin. Easy ordering and just what I expected.
By Kathleen P.
Proin works well for my dogs
May 13, 2020
My two dogs have been on Proin for several years now and it works well for them both. My usual supplier has been out of stock and unable to refill my prescriptions for more than two months. I found the medication in stock at Entirely Pets Pharmacy. The price is good, saving about $20 for each dog over what the veterinarian charges and the delivery is timely.
By Cj
Urgently needed medication
April 26, 2020
Quick and efficient. Needed Med ASAP since vet was out and you come through. Thank you.
By Keith
Port Charlotte Fl
Great product
April 19, 2020
This works great on our 1 1/2 year old Golden Retriever. Took awhile for it to get to us due to a back order but finally came. Will be buying here from now on, best price for it here.
By Suzan W.
April 3, 2020
Proin ER was just not doing the job with my dog's leakage after she had been on regular Proin for a year. Apparently this was a common problem as my vet told me they couldn't get it supplied anymore. All online sites were out but I
was very happy to find that you had it and dry life has been restored. Thank you Entirely Pets! Hopefully the manufacturer will continue to make the drug.
By bob
really works
February 7, 2019
our dog leaked urine, and this medicine stopped that from happening. there is an effect on the dog's demeanor, however.
  • stops urine leakage
  • dog seems somewhat spaced out on this stuff.
By Scott
Spokane, Wa
Cheaper price than elsewhere and fast shipping
July 18, 2018
I have ordered this for my dog for a few months and while I wish it was cheaper, it was at least cheaper then anyone else. Now that they have dealt with the Vet and the prescription, the process was very quick and it was shipped to my residence in a timely manner.
Merchant Response:Hi Scott, Here at EntirelyPets Pharmacy, we aim to give the best service to our customers. We appreciate your business.
By Chris
Works as described
May 30, 2018
Huge problem with older dogs is leaking bladder. This manages the issue.
By Abby C.
Great price
May 10, 2018
I was happy to see the larger size at a great price, Will be reordering
By Deb
nottingham, PA
November 24, 2017
Exactly what I ordered.
  • Just what I needed.
  • None
By Merrill
Great sale price!
November 11, 2017
Entirely pets, was quick and easy & it was a great sale price for Proin. These are pills that my dog needs. To control her incontinence, as she gets older?
Merchant Response:Hello Merrill, thank you for your comment and we are happy to hear the Proin is working well for your dog!
By Patty
For urinary incontinence in dogs
October 28, 2017
Entirely Pets Pharmacy is cooperative, convenient, and economical. Order received in good condition.
By Kathy
Proin: Incontinence
June 12, 2017
Has really been helping our 12 year Old Bull Mastiff with her kidney issues - Not totally sure what her issues are, we have had an ultra sound and they found no tumors - She was leaking/peeing in house, This has helped.
  • Is helping our dog so that is good.
By Bruce K.
Colorado Springs, CO
Fixed incontinence problems
May 3, 2017
Our 14 yr old dog was experiencing incontinence problems. Proin was the solution. She still has an occasional accident when she is sleeping at night but Proin solved the problem during the day and usually at night. Vast improvement when she started taking it!
Merchant Response:Thank you for the great feedback Bruce and we're so happy to hear that the Proin has made such a great difference for your dog!
By Rebecca
Independence OH
Very helpful to our Coco
April 21, 2017
Our 11 year old lab/shepherd always has had issues with her "private" area. At her most recent physical, vet suggested this drug. Coco is much more comfortable when taking this drug twice a day.
By Thomas
Great service
April 12, 2017
Good service and communication
By Thomas
Great service
April 12, 2017
Great service and communication
By Yvonne
Bellevue, Wa
Proin 50 mg/180 chewable tablets
March 29, 2017
Delivered as ordered. Great price, will order from this pharmacy again :).
My dog has been on Proin for the last 12 years of her 14 years to control her incontinence. To my knowledge, Proin has no nasty side effects.
By Donna H.
Perkasie, PA
Proin 75mg
March 24, 2017
Exactly what I wanted. Great price and came quickly.
By White B.
Product Works For Us
March 16, 2017
Although we had real trepidation about giving this medication to our dog because of some bad reviews online, our vet said she has never had a problem with any dog taking it. It really does work for our dog; no leaking at all since she began taking it. Recently had to up the dose to two tablets a day, with no problems at this point. The price is GREAT compared to what we were paying locally!!!
  • Works as prescribed;
  • MUCH less expensive here
  • None

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