Proin for Dogs | 25, 50, 75 mg | Free Shipping | EntirelyPets Rx
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Proin Chewable Tablets

Proin Chewable Tablets

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Recurring Saings in EprxAUTOSHIP & SAVE[Details]
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  • Arkansas, Illinois, Iowa, Louisiana, Oregon & West Virginia


Proin for dogs (phenylpropanolamine hydrochloride) is an FDA-Approved effective medication for managing and treating canine urinary incontinence. It is comes in a liver-flavored chewable tablet that makes for easy administration.

Proin Use

For the control of urinary incontinence due to urethral sphincter hypotonus in dogs

Animals Treated


Key Benefits

  • Is a supplement for urinary incontinence in dogs
  • Ensures sustained phenylpropanolamine levels in the bloodstream and may help reduce the conditions often associated with high levels of phenylpropanolamine such as decreased appetite, changes in heart rate, increased blood pressure, hyperexcitability
  • Palatable liver flavor

How It Works

Proin contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the bladder sphincter muscle, which helps to control urine leakage.

NADA #141-324


Active Ingredient

Phenylpropanolamine hydrochloride


Dosage and Administration

The total recommended dosage for oral administration is 2 mg/kg (0.91 mg/lb) of body weight twice daily. Proin is scored and dosage should be calculated in half-tablet increments. Give Proin exactly as directed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Proin at room temperature away from moisture and heat. Keep this medication away from children and pets.

View Proin drug facts sheet.

Quick Tips

  • The medication may be given with food.
  • Proin liver flavored chewable tablets are available by prescription for use in dogs to treat urinary incontinence.
  • Proin may cause restlessness, irritability, or loss of appetite.
  • Tell your veterinarian about any other medication you may be giving your pet.

Dosage Table

All weights2 mg/kg (0.91 mg/lb) of body weight twice daily

Storage Directions

Store at controlled room temperature 20-25°C (68-77°F), excursions permitted between 15-40°C (59-104°F) Keep out of reach of children and pets.


Proin may cause increased thirst. Make sure to provide ample fresh water. Don't give Proin with ephedrine or epinephrine, and don't give it within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar.


Not for human use. Keep out of reach of children. Consult a physician in case of accidental ingestion by humans./p>

Possible Side Effects

Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.


Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.
Seek emergency veterinary medical treatment. Symptoms of overdose may include increased blood pressure, increased heart rate, seizures or coma.
Do not give Proin with ephedrine or epinephrine and do not give within 2 weeks of using an MAOI such as selegiline or Preventic Collar.
Before giving Proin, tell your veterinarian if your pet is being given digoxin, NSAIDs such as aspirin or Rimadyl, tricyclic antidepressants such as clomipramine, and beta-blockers such as atenolol, or any other prescription or over the counter medications.
Tell your veterinarian if your pet has ever had an allergic reaction to this medication. Tell your veterinarian if your pet has glaucoma, hyperthyroid disease, diabetes, heart problems or high blood pressure. Tell your veterinarian if your pet is pregnant or lactating.

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