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Proin FOR DOGS is an effective and safe chewable supplemental product. Proin is a chewable tablets for the management and treatment of canine urinary incontinence.

  • Is a supplement for urinary incontinence in dogs
  • Ensures sustained phenylpropanolamine levels in the blood stream and may help reduce the conditions often associated with high levels of phenylpropanolamine such as: decreased appetite, changes in heart rate, increased blood pressure, hyperexcitability

  • How it works:Proin contains the active ingredient phenylpropanolamine, an adrenergic agent that works by tightening the bladder sphincter muscle, which helps to control urine leakage.

    Unable to ship to the following states:

  • Arkansas, Illinois, Iowa, Louisiana, Oregon & West Virginia

  • Prescription Required


    Dosage & Administration: The usual dose for dogs is 0.4-0.8mg/pound every 12 hours. Give Proin exactly as directed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. Store Proin at room temperature away from moisture and heat. Keep this medication away from children and pets.

  • Proin liver flavored chewable tablets are available by prescription for use in dogs to treat urinary incontinence.
  • Proin may cause restlessness, irritability, or loss of appetite.
  • Tell your veterinarian about any other medication you may be giving your pet.

  • Tip: Give this medication exactly as directed by your veterinarian. Do not exceed 1.8mg/lb per day. The medication may be given with food.

    Pet Weight Dosage
    Dogs: All weights Tablets: The usual dose for dogs is 0.4-0.8mg/pound every 12 hours. Drops: 0.4-0.8mg/pound every 12 hours.
    Cats: X X
    Horses: X X

    Storage: Should be stored at room temperature away from moisture and heat. Keep this medication away from children and pets.

    What happens if I miss giving a dose: Give the missed dose as soon as you remember during the same day. However, if you don't remember until the next day, skip the dose you missed and give only the next regularly scheduled dose. Do not give a double dose of the medication.

    What happens if I overdose the pet: Seek emergency veterinary medical treatment. Symptoms of overdose may include increased blood pressure, increased heart rate, seizures or coma.

    Possible side effects of Proin: Stop giving Proin and contact your veterinarian immediately if your pet has an allergic reaction (difficulty breathing; swelling of the lips, tongue, face; and hives). Other side effects that may occur include restlessness, irritability, increased heart rate, increased blood pressure and loss of appetite. Continue to give the medication and contact your veterinarian. Other less serious side effects may occur. Contact your veterinarian about any side effects that seem bothersome.

    What should I avoid while giving Proin to my pet: Do not give Proin with ephedrine or epinephrine and do not give within 2 weeks of using an MAOi such as selegilene or Preventic Collar.

    What other drugs will affect Proin: Before giving Proin, tell your veterinarian if your pet is being given digoxin, NSAIDs such as aspirin or Rimadyl, tricyclic antidepressants such as clomipramine, and beta blockers such as atenolol, or any other prescription or over the counter medications.

    What should I discuss with my veterinarian before giving Proin to my pet: Tell your veterinarian if your pet has ever had an allergic reaction to this medication. Tell your veterinarian if your pet has glaucoma, hyperthyroid disease, diabetes, heart problems or high blood pressure. Tell your veterinarian if your pet is pregnant or lactating.

    Cautions: Don't give Proin with ephedrine or epinephrine, and don't give it within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar. Possible side effects can occur, including restlessness, or loss of appetite, difficulty breathing, hives, and swelling of the lips, tongue, or face. If these or any other side effects occur, contact your veterinarian immediately.


    Review Summary
    14 Reviews
    86% (12)
    14% (2)
    0% (0)
    0% (0)
    0% (0)
    100% Recommend this product (14 of 14 responses)
    By Scott
    Spokane, Wa
    Cheaper price than elsewhere and fast shipping
    July 18, 2018
    I have ordered this for my dog for a few months and while I wish it was cheaper, it was at least cheaper then anyone else. Now that they have dealt with the Vet and the prescription, the process was very quick and it was shipped to my residence in a timely manner.
    Merchant Response:Hi Scott, Here at EntirelyPets Pharmacy, we aim to give the best service to our customers. We appreciate your business.
    By Chris
    Works as described
    May 30, 2018
    Huge problem with older dogs is leaking bladder. This manages the issue.
    By Abby C.
    Great price
    May 10, 2018
    I was happy to see the larger size at a great price, Will be reordering
    By Deb
    nottingham, PA
    November 24, 2017
    Exactly what I ordered.
    ProsJust what I needed.
    By Merrill
    Great sale price!
    November 11, 2017
    Entirely pets, was quick and easy & it was a great sale price for Proin. These are pills that my dog needs. To control her incontinence, as she gets older?
    Merchant Response:Hello Merrill, thank you for your comment and we are happy to hear the Proin is working well for your dog!
    By Patty
    For urinary incontinence in dogs
    October 28, 2017
    Entirely Pets Pharmacy is cooperative, convenient, and economical. Order received in good condition.
    By Kathy
    Proin: Incontinence
    June 12, 2017
    Has really been helping our 12 year Old Bull Mastiff with her kidney issues - Not totally sure what her issues are, we have had an ultra sound and they found no tumors - She was leaking/peeing in house, This has helped.
    ProsIs helping our dog so that is good.
    By Bruce K.
    Colorado Springs, CO
    Fixed incontinence problems
    May 3, 2017
    Our 14 yr old dog was experiencing incontinence problems. Proin was the solution. She still has an occasional accident when she is sleeping at night but Proin solved the problem during the day and usually at night. Vast improvement when she started taking it!
    Merchant Response:Thank you for the great feedback Bruce and we're so happy to hear that the Proin has made such a great difference for your dog!
    By Rebecca
    Independence OH
    Very helpful to our Coco
    April 21, 2017
    Our 11 year old lab/shepherd always has had issues with her "private" area. At her most recent physical, vet suggested this drug. Coco is much more comfortable when taking this drug twice a day.
    By Thomas
    Great service
    April 12, 2017
    Good service and communication
    By Thomas
    Great service
    April 12, 2017
    Great service and communication
    By Yvonne
    Bellevue, Wa
    Proin 50 mg/180 chewable tablets
    March 29, 2017
    Delivered as ordered. Great price, will order from this pharmacy again :).
    My dog has been on Proin for the last 12 years of her 14 years to control her incontinence. To my knowledge, Proin has no nasty side effects.
    By Donna H.
    Perkasie, PA
    Proin 75mg
    March 24, 2017
    Exactly what I wanted. Great price and came quickly.
    By White B.
    Product Works For Us
    March 16, 2017
    Although we had real trepidation about giving this medication to our dog because of some bad reviews online, our vet said she has never had a problem with any dog taking it. It really does work for our dog; no leaking at all since she began taking it. Recently had to up the dose to two tablets a day, with no problems at this point. The price is GREAT compared to what we were paying locally!!!
    ProsWorks as prescribed; MUCH less expensive here