CEFTIFLEX® is a sterile powder which contains Sodium Salt of Ceftiofur, a broad-spectrum Cephalosporin antibiotic active against gram-positive and gram-negative bacteria, including B-lactamase producing strains. For cattle, swine, sheep, goats, horses, dogs, chicks and turkey poults.
Horses CEFTIFLEX® is indicated for treatment of respiratory infections in horses associated with Streptococcus zooepidemicus. Dogs CEFTIFLEX® is indicated for the treatment of canine urinary tract infections associated with Escherichia coli and Proteus mirabilis.
Each mL of the reconstituted drug contains ceftiofur sodium equivalent to 50 mg ceftiofur. The pH was adjusted with sodium hydroxide and monobasic potassium phosphate.
Dogs: Administer to dogs by subcutaneous injection at the dosage of 1.0 mg ceftiofur per pound (2.2 mg/kg) of body weight (0.1 mL reconstituted sterile solution per 5 lbs body weight). Treatment should be repeated at 24-hour intervals for 5-14 days.
Reconstituted CEFTIFLEX® is to be administered to dogs by subcutaneous injection. No vial closure should be entered more than 20 times. Therefore, only the 1 gram vial is approved for use in dogs.
Horses: Administer to horses by intramuscular injection at the dosage of 1.0 to 2.0 mg ceftiofur per pound (2.2 to 4.4 mg/kg) of body weight (2-4 mL reconstituted sterile solution per 100 lbs body weight). A maximum of 10 mL may be administered per injection site.
Treatment should be repeated at 24-hour intervals, continued for 48 hours after clinical signs have disappeared and should not exceed 10 days.
STORAGE: Store unreconstituted product at controlled room temperature 20° to 25° C (68° to 77° F) [see USP].
Store reconstituted product either in a refrigerator 2° to 8°C (36° to 46° F) for up to 7 days or at controlled room temperature 20° to 25° C (68° to 77° F) [see USP] for up to 12 hours. Protect from light. Color may vary from off-white to a tan color. Color does not affect potency.