Durvet Ivermectin Injection

Ivermectin Injection 1% Sterile Solution is a parasiticide for the treatment and control of internal and external parasites of cattle and swine. Indicated for effective treatment and control of gastrointestinal roundworms, lungworms, grubs, sucking lice, and mange mites in cattle and gastrointestinal roundworms, lungworms, lice, and mange mites in swine.

Key Benefits

• Broad Spectrum: effective against a wide range of external and internal parasites in beef cattle and swine
• Convenient: single, small volume dose required
• Effective: causes paralysis and death of parasites and helps prevent reinfection
• Package safety: rigid plastic vials provide for a firm grip and prevent breakage, individual vial cartons protect vial contents from sunlight
• Economical: inexpensive on a cost per dose basis
• Safe: approved by FDA

View Durvet Ivermectin Injection Drug Facts Sheet.

Indications:

Cattle: Ivermectin Injection is indicated for the effective treatment and control of harmful species of gastrointestinal roundworms, lungworms, grubs, sucking lice, and mange mites in cattle,

Swine: Ivermectin Injection is indicated for the effective treatment and control of harmful species of gastrointestinal roundworms, lungworms, lice, and mange mites in swine.

Dosage:

Cattle: Ivermectin Injection should be given only by subcutaneous injection under the loose skin in front of or behind the shoulder at the recommended dose level of 200 mcg of ivermectin per kilogram of body weight. Each mL of Ivermectin Injection contains 10 mg of ivermection, sufficient to treat 110 lb (50 kg) of body weight (maximum 10 mL per injection site).

Body Weight (lb)	Dose Volume (mL)
220	2
330	3
440	4
550	5
660	6
770	7
880	8
990	9
1100	10

Swine: Ivermectin Injection should be given only by subcutaneous injection in the neck of swine at the recommended dose level of 300 mcg of ivermectin per kilogram (2.2 lb) of body weight. Each mL of Ivermectiin Injection contains 10 mg of ivermectin, sufficient to treat 75 lb of body weight.

Body Weight (lb)	Dose Volume (mL)
Growing Pigs
19	1/4
38	1/2
75	1
150	2
Breeding Animals (Sows, Gilts, and Boars)
225	3
300	4
375	5
450	6

Administration

Cattle: Ivermectin Injection is to be given subcutaneously only, to reduce risk of potentially fatal clostridial infection of the injection site. Animals should be appropriately restrained to achieve the proper route of administration. Use of a 16-gauge, 1/2 to 3/4 needle is suggested. Inject under the loose skin in front of or behind the shoulder.

When using the 50 mL, 250 mL, or 500 mL package size, use only automatic syringe equipment. Use sterile equipment and sanitize the injection site by applying a suitable disinfectant.

Clean, properly disinfected needles should be used to reduce the potential for injection site infections. No special handling or protective clothing is necessary.

Swine: Ivermectin (ivermectin) Injection is to be given subcutaneously in the neck. Animals should be appropriately restrained to achieve the proper route of administration. Use of a 16 or 18 gauge needle is suggested for sows and boars, while an 18 or 20 gauge needle may be appropriate for your animals. Inject under the skin, immediately behind the ear.

When using the 50 mL, 250 mL or 500 mL package size, use only automatic syringe equipment. As with any injection, sterile equipment should be used. The injection site should be cleaned and disinfected with alcohol before injection. The rubber stopper should also be disinfected with alcohol to prevent contamination of the contents. Mild and transient pain reactions may be seen in some swine following subcutaneous administration.

Recommended Treatment Program

Swine: At the time of initiating any parasite control program, it is important to treat all breeding animals in the herd. After the initial treatment, use Ivermectin Injection regularly as follows:

Breeding Animals

• Sows: Treat prior to farrowing, preferably 7-14 days before, to minimize infection of piglets.
• Gilts: Treat 7-14 days prior to breeding. Treat 7-14 days prior to farrowing.
• Boars: Frequency and need for treatments are dependent upon exposure. Treat at least two times a year.

Feeder Pigs (Weeners/Growers/Finishers)

All weaner/feeder pigs should be treated before placement in clean quarters. Pigs exposed to contaminated soil or pasture may need retreatment if reinfection occurs.

Note:

1. Ivermectin Injection has a persistent drug level sufficient to control mite infestations throughout the egg to adult life cycle. However, since the ivermectin effect is not immediate, care must be taken to prevent reinfestation from exposure to untreated animals or contaminated facilities. Generally, pigs should not be moved to clean quarters or exposed to uninfested pigs for approximately one week after treatment. Sows should be treated at least one week before farrowing to minimize transfer of mites to newborn baby pigs
2. Louse eggs are unaffected by Ivermectin Injection and may require up to three weeks to hatch. Louse infestations developing from hatching eggs may require retreatment.
3. Consult a veterinarian for aid in the diagnosis and control of internal and external parasites of swine.

Special Minor Use

Reindeer: For the treatment and control of warbles Oedemagena tarandi) in reindeer, inject 200 micrograms ivermectin per kilogram of body weight, subcutaneously. Follo use directions for cattle as described under Administration.

American Bison: For the treatment and control of grubs (Hypoderma bovis) in American bison, inject 200 micrograms ivermectin per kilogram of body weight, subcutaneously. Follow use directions for cattle as described under Administration.

Residue Warning: Do not treat reindeer or American bison within 8 weeks (56 days) of slaughter.

Warning-Not for use in Humans

Keep this and all drugs out of the reach of children.

The Material Safety Data Sheet (MSDS) contains more detailed occupational safety information. To report adverse effects, obtain an MSDS or for assistance, contact Durvet, Inc. at 1-800-821-5570.

Residue Warning:

Do not treat cattle within 35 days of slaughter. Because a withdrawal time in milk has not been established, do not use in female dairy cattle of breeding age. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal. Do not treat swine within 18 days of slaughter.

Precautions

Transitory discomfort has been observed in some cattle following subcutaneous administration. A low incidence of soft tissue swelling at the injection site has been observed. These reactions have disappeared without treatment. For cattle, divide doses greater than 10 mL between two injection sites to reduce occasional discomfort or site reaction.

Use sterile equipment and sanitize the injection site by applying a suitable disinfectant. Clean, properly disinfected needles should be used to reduce the potential for injection site infections. Observe cattle for injection site reactions. Reactions may be due to clostridial infection and should be aggressively treated with appropriate antibiotics. If injection site infections are suspected, consult your veterinarian. This product is not for intravenous or intramuscular use.

Protect product from light. Ivermectin Injection for Cattle and Swine has been developed specifically for use in cattle, swine, reindeer, and American bison only. This product should not be used in other animal species as severe adverse reactions, including fatalities in dogs, may result.

Restricted Drug (California) - Use Only as Directed

When to Treat Cattle with Grubs

Ivermectin Injection effectively controls all stages of cattle grubs. However, proper timing of treatment is important. For most effective results, cattle should be treated as soon as possible after the end of the heel fly (warble fly) season. Destruction of Hypoderma larvae (cattle grubs) at the period when these grubs are in vital areas may cause undesirable host-parasite reactions including the possibility of fatalities. Killing Hypoderma lineatum when it is in the vertebral canal may cause staggering or paralysis. These reactions are not specific to treatment with Ivermectin Injection, but can occur with any successful treatment of grubs. Cattle should be treated either before or after these stages of grub development. Consult your veterinarian concerning the proper time for treatment.

Cattle treated with Ivermectin Injection after the end of the heel fly season may be treated with Ivermectin Injection during the winter for internal parasites, mange mites, or sucking lice without danger of grub-related reactions. A planned parasites control program is recommended.

Environmental Safety

Studies indicate that when ivermectin comes in contact with soil, it readily and tightly binds to the soil and becomes inactive over time. Free ivermectin may adversely affect fish and certain aquatic organisms on which they feed. Do not permit water runoff from feedlots or production sites to enter lakes, streams or ponds. Do not contaminate water by direct application or by the improper disposal of drug containers. Dispose of containers in an approved landfill or by incineration.

As with other avermectiins, Ivermectin is excreted in the dung of treated animals and can inhibit the reproduction and growth of pest and beneficial insects that use dung as a source of food and for reproduction. The magnitude and duration of such effects are species and life-cycle specific. When used according to label directions, the product is not expected to have an adverse impact on populations of dung-dependant insects.