Trifexis For Dogs 60.1-120 Lbs (6 Chew Tabs)

Item# HA21251533


* Pet Food & Other Exclusions

Regular: $127.99
Sale: $109.99
Recurring Saings in Eprx



Trifexis for Dogs - Brown protects petite dogs from fleas, heartworms, hookworms, roundworms, and whipworms.

 This chewable tablet features a scrumptious beef flavor that makes it easy to administer your pet’s monthly dose. By combining spinosad and milbemycin oxide, this treatment combats parasites for a full month and begins working within 30 minutes of administering the first dose.

Triflexis is a prescription medication that is safe for dogs that are at least 8 weeks of age. There are also five different formulations of Triflexis to give the proper dosage based on your dog’s weight. This pack includes 6 months worth of 140 mg doses for dogs that are between 5 and 10 pounds- but there are also dosages for dogs that weigh 11-20 pounds, 21-40 pounds, 41-60 pounds, and 61-120 pounds.

Key Features:
  • Begins killing fleas 30 minutes after application and kills 100% of biting fleas after 4 hours
  • Prevents heartworm disease
  • Treats and controls roundworms, hookworms, and whipworms
  • Palatable beef flavor and real pork liver makes tablet easy to administer

  • How it works: Spinosad, an active ingredient in Trifexis, starts to work within 30 minutes to kill fleas and has been proven to kill 100% of all biting fleas within 4 hours. Trifexis also kills flea eggs before they can mature, which helps to end the flea life cycle. Trifexis prevents heartworm disease by killing microfilariae and larvae from maturing into adult heartworms.

    Side effects
  • Vomiting and diarrhea
  • Cough
  • Increased thirst and/or appetite
  • Redness of skin
  • Anorexia
  • Lethargy or hyperactivity
  • Vocalization
  • Excessive salivation

  • Prescription Required


    Trifexis for Dogs 5 to 10 lbs:
    Active Ingredients per tablet Amount
    Spinosad 140 mg
    Milbemycin oxime 2.3 mg

    Trifexis for Dogs 10.1 to 20 lbs:
    Active Ingredients per tablet Amount
    Spinosad 270 mg
    Milbemycin oxime 4.5 mg

    Trifexis for Dogs 20.1 to 40 lbs:
    Active Ingredients per tablet Amount
    Spinosad 560 mg
    Milbemycin oxime 9.3 mg

    Trifexis for Dogs 40.1 to 60 lbs:
    Active Ingredients per tablet Amount
    Spinosad 810 mg
    Milbemycin oxime 13.5 mg

    Trifexis for Dogs 60.1 to 120 lbs:
    Active Ingredients per tablet Amount
    Spinosad 1620 mg
    Milbemycin oxime 27 mg


    Dosage & Administration: Give Trifexis chewable tablets with food. Give Trifexis chewable tablets once a month. Trifexis chewable tablets may be chewed, offered in food, or administered like other tablet medications. If vomiting occurs within 1 hour of administration, redose the pet with another full dose. Store Trifexis at room temperature (68-77° F). Consult your veterinarian for pregnant or lactating dogs.

  • Please view the chart below for the correct dosage of Trifexis for your dog.

  • Tip: Trifexis does not protect against ticks.
    Pet Weight Dosage
    (Over 8 weeks of age)
    5 - 10 lbs Give one tablet (Pink label box)
    0.1 - 20 lbs Give one tablet (Orange label box)
      20.1 - 40 lbs Give one tablet (Green label box)
      40.1 - 60 lbs Give one tablet (Blue label box)
      60.1 - 120 lbs Give one tablet (Brown label box)
    Over 120 lbs Administer the appropriate combination of tablets
    Horses: X X
    Cats: X X
    Storage: Should be stored at room temperature. Keep away from pets and children.

    What happens if I miss giving a dose: Give the missed dose with food as soon as you remember and resume a monthly dosing schedule.

    What happens if I overdose the pet: Overdose of this medication is unlikely. However, if an overdose is suspected, contact your veterinarian or veterinary emergency room. Symptoms of overdose that may occur include vomiting.

    What should I avoid while giving Trifexis: Your pet may maintain normal activities and interactions while being given Trifexis. The safe use of Trifexis chewable tablets in male dogs intended for breeding has not been established.

    What are the possible side effects of Trifexis: Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Trifexis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, redness of the skin, hyperactivity and excessive salivation. Talk to your veterinarian about any side effect that seems unusual or especially bothersome to the pet.

    What other drugs will affect Trifexis: Talk to your veterinarian before giving any prescription or over the counter medications.

    What should I discuss with my veterinarian before giving Trifexis: Tell your veterinarian if you are planning on breeding your pet. Tell your veterinarian if your dog has a history of seizures (epilepsy).

    Cautions: Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, one of the components of Trifexis chewable tablets. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy. Puppies less than 14 weeks of age may experience a higher rate of vomiting. Consult your veterinarian for pregnant or lactating dogs.


    7 Reviews
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    86% Recommend this product (6 of 7 responses)
    By Carla
    Little River, SC
    December 6, 2017
    Great price
    Quick shipping after receiving the prescription from our veterans. Super price on one of the newest heartworm/ flea medications.
    By Wendy
    April 26, 2017
    Great Service!
    Entirely Pets kept me updated all along the way from letting me know they had contacted my vet, when they got the prescription, when it shipped and asking if it arrived when it was supposed to. The process was extremely fast and my product was at my door in less than a week. Everything was perfect!
    ProsGreat service, wonderful product and excellent price.
    By Linda Scamardo
    Bryan, TX
    March 16, 2017
    Ordering online has been so convenient for me and saving money also, This will be the only way I will order from now on. EntirelyPets is a friendly use website and I have recommended them to my family and friends.
    By Susan
    Saint Charles
    October 23, 2016
    Great price but real headache to purchase
    Price was great. However, my prescription from Vetco was not readily accepted. Way too much time had to be spent to get heartworm meds for my dog.
    ProsGreat price
    ConsPrescription process was a complete mess
    By DeenaM
    Charleston WV
    January 5, 2016
    Quick Delivery
    I have been using Trifexis for years and always look for the best pricing. This was the lowest I could find, and the delivery time was really quick especially since it was shipped cross country!
    By Bogeyman
    Downey, California
    October 2, 2015
    Easy purchase, good price
    Was looking for a place to buy my dog's Trifexis. Ended up selecting It was a simple process, with a 20% discount on my prescription. Once the prescription was filled, it was shipped to my house very quickly. I will definitely be going back to them for a refill.
    Prosgreat pricing. fast processing. easy and simple ordering process.
    By Jan
    July 5, 2015
    1st purchase of Trifexis
    Good communication regarding order details. Good price & quick shipment of 6 months Trifexis for both of my dogs. Will buy again.