Trifexis For Dogs 60.1-120 Lbs (12 Chew Tabs)

Item# 2125153312


* Pet Food & Other Exclusions

Regular: $254.99
Sale: $217.99
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Trifexis for Dogs - Brown protects petite dogs from fleas, heartworms, hookworms, roundworms, and whipworms.

 This chewable tablet features a scrumptious beef flavor that makes it easy to administer your pet’s monthly dose. By combining spinosad and milbemycin oxide, this treatment combats parasites for a full month and begins working within 30 minutes of administering the first dose.

Triflexis is a prescription medication that is safe for dogs that are at least 8 weeks of age. There are also five different formulations of Triflexis to give the proper dosage based on your dog’s weight. This pack includes 6 months worth of 140 mg doses for dogs that are between 5 and 10 pounds- but there are also dosages for dogs that weigh 11-20 pounds, 21-40 pounds, 41-60 pounds, and 61-120 pounds.

Key Features:
  • Begins killing fleas 30 minutes after application and kills 100% of biting fleas after 4 hours
  • Prevents heartworm disease
  • Treats and controls roundworms, hookworms, and whipworms
  • Palatable beef flavor and real pork liver makes tablet easy to administer

  • How it works: Spinosad, an active ingredient in Trifexis, starts to work within 30 minutes to kill fleas and has been proven to kill 100% of all biting fleas within 4 hours. Trifexis also kills flea eggs before they can mature, which helps to end the flea life cycle. Trifexis prevents heartworm disease by killing microfilariae and larvae from maturing into adult heartworms.

    Side effects
  • Vomiting and diarrhea
  • Cough
  • Increased thirst and/or appetite
  • Redness of skin
  • Anorexia
  • Lethargy or hyperactivity
  • Vocalization
  • Excessive salivation

  • Prescription Required


    Trifexis for Dogs 5 to 10 lbs:
    Active Ingredients per tablet Amount
    Spinosad 140 mg
    Milbemycin oxime 2.3 mg

    Trifexis for Dogs 10.1 to 20 lbs:
    Active Ingredients per tablet Amount
    Spinosad 270 mg
    Milbemycin oxime 4.5 mg

    Trifexis for Dogs 20.1 to 40 lbs:
    Active Ingredients per tablet Amount
    Spinosad 560 mg
    Milbemycin oxime 9.3 mg

    Trifexis for Dogs 40.1 to 60 lbs:
    Active Ingredients per tablet Amount
    Spinosad 810 mg
    Milbemycin oxime 13.5 mg

    Trifexis for Dogs 60.1 to 120 lbs:
    Active Ingredients per tablet Amount
    Spinosad 1620 mg
    Milbemycin oxime 27 mg


    Dosage & Administration: Give Trifexis chewable tablets with food. Give Trifexis chewable tablets once a month. Trifexis chewable tablets may be chewed, offered in food, or administered like other tablet medications. If vomiting occurs within 1 hour of administration, redose the pet with another full dose. Store Trifexis at room temperature (68-77° F). Consult your veterinarian for pregnant or lactating dogs.

  • Please view the chart below for the correct dosage of Trifexis for your dog.

  • Tip: Trifexis does not protect against ticks.
    Pet Weight Dosage
    (Over 8 weeks of age)
    5 - 10 lbs Give one tablet (Pink label box)
    0.1 - 20 lbs Give one tablet (Orange label box)
      20.1 - 40 lbs Give one tablet (Green label box)
      40.1 - 60 lbs Give one tablet (Blue label box)
      60.1 - 120 lbs Give one tablet (Brown label box)
    Over 120 lbs Administer the appropriate combination of tablets
    Horses: X X
    Cats: X X
    Storage: Should be stored at room temperature. Keep away from pets and children.

    What happens if I miss giving a dose: Give the missed dose with food as soon as you remember and resume a monthly dosing schedule.

    What happens if I overdose the pet: Overdose of this medication is unlikely. However, if an overdose is suspected, contact your veterinarian or veterinary emergency room. Symptoms of overdose that may occur include vomiting.

    What should I avoid while giving Trifexis: Your pet may maintain normal activities and interactions while being given Trifexis. The safe use of Trifexis chewable tablets in male dogs intended for breeding has not been established.

    What are the possible side effects of Trifexis: Side effects that may occur include vomiting. If vomiting occurs within one hour of administration, redose with another full dose. Other side effects may occur. Continue giving Trifexis chewable tablets and talk to your veterinarian if your pet experiences decreased appetite, lethargy or decreased activity, diarrhea, cough, increased thirst, vocalization, increased appetite, redness of the skin, hyperactivity and excessive salivation. Talk to your veterinarian about any side effect that seems unusual or especially bothersome to the pet.

    What other drugs will affect Trifexis: Talk to your veterinarian before giving any prescription or over the counter medications.

    What should I discuss with my veterinarian before giving Trifexis: Tell your veterinarian if you are planning on breeding your pet. Tell your veterinarian if your dog has a history of seizures (epilepsy).

    Cautions: Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, one of the components of Trifexis chewable tablets. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy. Puppies less than 14 weeks of age may experience a higher rate of vomiting. Consult your veterinarian for pregnant or lactating dogs.


    1 Reviews
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    100% Recommend this product (1 of 1 responses)
    By Kenny
    Puyallup, Washington
    November 22, 2017
    Chewable Flea Meds
    Quick shipping, easy process with a fantastic low price...
    Merchant Response:Thank you for the feedback Kenny, glad we were able to get the Trifexis to you quickly!