Interceptor Plus for Dogs 25.1-50 lbs Yellow (6 Chews) | EP Rx
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Interceptor Plus for Dogs 25.1-50 lbs. Prevention for Heartworm + 4 Other Worms | 6 Chews, 6-Month Supply Video

Interceptor Plus for Dogs 25.1-50 lbs. Prevention for Heartworm + 4 Other Worms | 6 Chews, 6-Month Supply

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Description

Interceptor Plus is a brand of medication that is used to prevent and control certain internal parasites in dogs. It is commonly prescribed by veterinarians to protect dogs from heartworm disease, as well as to treat and control other common parasites such as roundworms, hookworms, whipworms, and tapeworms.

The active ingredients in Interceptor Plus include milbemycin oxime and praziquantel. Milbemycin oxime is effective against heartworm larvae in the dog's bloodstream, preventing the development of adult heartworms. It also controls and treats intestinal parasites by interfering with their nervous system. Praziquantel specifically targets tapeworms, causing muscle spasms and paralysis that lead to their expulsion from the dog's body.

Interceptor Plus comes in the form of chewable tablets, which are usually administered once a month. The dosage depends on the dog's weight, and it's important to follow the veterinarian's instructions for proper administration. Regular use of Interceptor Plus can help protect dogs from a range of internal parasites and maintain their overall health.

Key Benefits:

  • Heartworm Disease Prevention: Interceptor Plus is highly effective in preventing heartworm disease, which is a potentially life-threatening condition caused by the transmission of heartworm larvae through mosquito bites. Regular administration of Interceptor Plus can protect dogs from heartworm infection and the serious health consequences associated with it.
  • Broad-Spectrum Parasite Control: Interceptor Plus not only prevents heartworm disease but also controls and treats other common internal parasites in dogs. It targets and eliminates roundworms, hookworms, whipworms, and tapeworms, helping to maintain the overall health and well-being of dogs.
  • Convenient Administration: Interceptor Plus comes in the form of tasty chewable tablets, making it easier to administer to dogs. Many dogs enjoy the flavor of the tablets, which can simplify the process of giving them medication. This convenience factor can help ensure that dogs receive their monthly dose consistently.
  • Veterinarian Recommended: Interceptor Plus is a prescription medication that is recommended and prescribed by veterinarians. Veterinarians have the expertise to assess your dog's specific needs, taking into account factors such as weight, health history, and potential exposure to parasites. Their recommendation ensures that your dog receives the most appropriate and effective parasite prevention and control.
  • Overall Health Benefits: By preventing and treating internal parasites, Interceptor Plus contributes to the overall health and well-being of dogs. Parasite infections can cause a variety of health problems, including digestive issues, weight loss, anemia, and in severe cases, organ damage. By keeping these parasites in check, Interceptor Plus helps maintain optimal health and quality of life for dogs.

Indications:

  • Prevention of Heartworm Disease: Interceptor Plus is used to prevent heartworm disease caused by the parasitic worm Dirofilaria immitis. It kills the immature heartworm larvae (microfilariae) that are transmitted to dogs through mosquito bites, preventing them from developing into adult heartworms.
  • Control and Treatment of Roundworms: Interceptor Plus is effective against the gastrointestinal roundworms Toxocara canis and Toxascaris leonina. It helps control and treat these common intestinal parasites in dogs, preventing their growth and reproduction.
  • Control and Treatment of Hookworms: Interceptor Plus is indicated for the control and treatment of Ancylostoma caninum and Uncinaria stenocephala, which are hookworms that can infect dogs. These parasites can cause anemia and other health issues in dogs, and Interceptor Plus helps eliminate and prevent their infestation.
  • Control and Treatment of Whipworms: Whipworms (Trichuris vulpis) can cause gastrointestinal issues and inflammation in dogs. Interceptor Plus is effective in controlling and treating whipworm infections, reducing the number of adult worms in the intestine.
  • Control and Treatment of Tapeworms: Interceptor Plus contains praziquantel, which is effective against tapeworms in dogs, including Dipylidium caninum and Taenia pisiformis. It causes muscle spasms and paralysis in the tapeworms, leading to their expulsion from the dog's body.

It's important to note that Interceptor Plus is meant for dogs and should not be used in other animal species or humans. The dosage and administration instructions should be followed as prescribed by a veterinarian to ensure the safety and effectiveness of the treatment.

How it works:

Interceptor Plus works through the combined action of its active ingredients, milbemycin oxime and praziquantel, to provide broad-spectrum parasite control in dogs. Here's how it works:

  1. Milbemycin Oxime: This ingredient primarily targets heartworms, as well as other intestinal parasites such as roundworms, hookworms, and whipworms. When administered to a dog, milbemycin oxime is absorbed into the bloodstream, where it circulates throughout the body. It works by interfering with the nerve transmission in the parasites, leading to paralysis and ultimately their death. It prevents heartworm larvae from developing into adult heartworms, thus protecting dogs from heartworm disease. It also controls and treats the other mentioned intestinal parasites.
  2. Praziquantel: This ingredient specifically targets tapeworms. After ingestion, praziquantel is rapidly absorbed from the dog's digestive system into the bloodstream. It then targets the tapeworms in the dog's intestine. Praziquantel disrupts the tapeworms' integument, leading to severe muscle spasms and paralysis. This paralysis weakens the tapeworms' grip on the intestinal wall, allowing them to be expelled from the dog's body through normal bowel movements.

By combining milbemycin oxime and praziquantel, Interceptor Plus provides comprehensive protection against heartworms, roundworms, hookworms, whipworms, and tapeworms. It effectively controls and treats these parasites, helping to maintain the health and well-being of dogs.

It's important to follow the veterinarian's instructions for dosage and administration to ensure the proper effectiveness of Interceptor Plus and to give the medication regularly as prescribed for optimal parasite prevention and control.

Ingredients

Interceptor Plus for Dogs 2-8 lbs (Orange):
Active Ingredients (per flavor tab) Amount
Milbemycin Oxime 2.3 mg
Praziquantel 22.5 mg
Interceptor Plus for Dogs 8.1-25 lbs (Green):
Active Ingredients (per flavor tab) Amount
Milbemycin Oxime 5.75 mg
Praziquantel 57 mg
Interceptor Plus for Dogs 25.1-50 lbs (Yellow):
Active Ingredients (per flavor tab) Amount
Milbemycin Oxime 11.5 mg
Praziquantel 114 mg
Interceptor Plus for Dogs 50.1-100 lbs (Blue):
Active Ingredients (per flavor tab) Amount
Milbemycin Oxime 23 mg
Praziquantel 228 mg

Directions

View Interceptor Plus Drug Facts Sheet

Interceptor Plus should be administered orally, once every month, at the minimum dosage of 0.23 mg/lb (0.5 mg/kg) milbemycin oxime, and 2.28 mg/lb (5 mg/kg) praziquantel. For heartworm prevention, give once monthly for at least 6 months after exposure to mosquitoes (see Effectiveness).

Dosage Schedule
Body Weight Milbemycin Oxime per chewable Praziquantel per chewable Number of chewables
2 to 8 lbs. 2.3 mg 22.8 mg 1
8.1 to 25 lbs. 5.75 mg 57 mg 1
25.1 to 50 lbs. 11.5 mg 114 mg 1
50.1 to 100 lbs. 23 mg 228 mg 1
Over 100 lbs. Administer the appropriate combination of chewables.

Interceptor Plus may be offered to the dog by hand or added to a small amount of dog food. The chewables should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Chewables may be broken into pieces and fed to dogs that normally swallow treats whole. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes after administration to ensure that no part of the dose is lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.

Heartworm Prevention:

Interceptor Plus should be administered at monthly intervals beginning within 1 month of the dog's first seasonal exposure to mosquitoes and continuing until at least 6 months after the dog's last seasonal exposure (see Effectiveness). Interceptor Plus may be administered year-round without interruption. When switching from another heartworm preventative product to Interceptor Plus, the first dose of Interceptor Plus should be given within a month of the last dose of the former product.

Intestinal Nematode and Cestode Treatment and Control:

Dogs may be exposed to and can become infected with roundworms, whipworms, hookworms, and tapeworms throughout the year, regardless of season or climate. Clients should be advised of appropriate measures to prevent reinfection of their dog with intestinal parasites. Because the prepatent period for E. multilocularis may be as short as 26 days, dogs treated at the labeled monthly intervals may become reinfected and shed eggs between treatments.

Contraindications:

There are no known contraindications to the use of Interceptor Plus.

Warnings:

Not for use in humans. Keep this and all drugs out of the reach of children.

Precautions:

Treatment with fewer than 6 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention (see Effectiveness).

Prior to administration of Interceptor Plus, dogs should be tested for existing heartworm infections. At the discretion of the veterinarian, infected dogs should be treated to remove adult heartworms. Interceptor Plus is not effective against adult D. immitis.

Mild, transient hypersensitivity reactions, such as labored breathing, vomiting, hypersalivation, and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae.

Do not use in puppies less than six weeks of age.

Do not use in dogs or puppies less than two pounds of body weight.

The safety of Interceptor Plus has not been evaluated in dogs used for breeding or in lactating females. Studies have been performed with milbemycin oxime alone (see Animal Safety).

Information for Owner or Person Treating Animal:

Echinococcus multilocularis and Echinococcus granulosus are tapeworms found in wild canids and domestic dogs. E. multilocularis and E. granulosus can infect humans and cause serious disease (alveolar hydatid disease and hydatid disease, respectively). Owners of dogs living in areas where E. multilocularis or E. granulosus are endemic should be instructed on how to minimize their risk of exposure to these parasites, as well as their dog's risk of exposure. Although Interceptor Plus was 100% effective in laboratory studies in dogs against E. multilocularis and E. granulosus, no studies have been conducted to show that the use of this product will decrease the incidence of alveolar hydatid disease or hydatid disease in humans. Because the prepatent period for E. multilocularis may be as short as 26 days, dogs treated at the labeled monthly intervals may become reinfected and shed eggs between treatments.

Effectiveness:

Heartworm Prevention:

In a well-controlled laboratory study, Interceptor Plus was 100% effective against induced heartworm infections when administered once monthly for 6 consecutive months. In well-controlled laboratory studies, neither one dose nor two consecutive doses of Interceptor Plus provided 100% effectiveness against induced heartworm infections.

Intestinal Nematodes and Cestodes Treatment and Control:

Elimination of the adult stage of hookworm (Ancylostoma caninum), roundworm (Toxocara canis, Toxascaris leonina), whipworm (Trichuris vulpis) and tapeworm (Echinococcus multilocularis, Echinococcus granulosus, Taenia pisiformis and Dipylidium caninum) infections in dogs was demonstrated in well-controlled laboratory studies.

Palatability:

In a field study of 115 dogs offered Interceptor Plus, 108 dogs (94.0%) accepted the product when offered from the hand as if a treat, 1 dog (0.9%) accepted it from the bowl with food, 2 dogs (1.7%) accepted it when it was placed in the dog's mouth, and 4 dogs (3.5%) refused it.

Animal Safety:

Interceptor Plus:

In a repeated dose safety study, 40 ten-week-old puppies (10 per group) were dosed with either a sham dose (0X) or 1, 3, or 5X the maximum label exposure of Interceptor Plus every 14 days for a total of seven treatments. Ataxia, lethargy, and salivation were seen in the 3X and 5X treated dogs following each of the seven doses. Vomiting was seen in all treatment groups but had a higher incidence in the 3X and 5X treatment groups.

In a repeated dose safety study, 64 six-week-old puppies (16 per group) were dosed with either a sham dose (0X) or 1, 3, or 5X the maximum label exposure of Interceptor Plus every 14 days for a total of four treatments. Lethargy was observed in all groups. Ataxia was observed in the three treated groups, including one dog in the 1X treated group. For both lethargy and ataxia the incidence and duration increased in the 3X and 5X groups. These signs were observed during the first 24 hours following treatment. Salivation and tremors were observed in the 3X and 5X treated dogs beginning immediately after dosing and up to six hours post dose. Vomiting was only observed in the 5X treatment group on most, but not all, treatment days.

For Interceptor Plus the maximum exposure based on product dosing is 2.5 mg/kg for milbemycin oxime and 25.1 mg/kg for praziquantel, which is higher than the minimum effective dose used in the safety studies for milbemycin oxime (see below).

Milbemycin Oxime:

Two studies were conducted in heartworm-infected dogs treated with milbemycin oxime. Mild, transient hypersensitivity reactions were observed in dogs with high microfilariae counts (see Precautions).

Safety studies in pregnant dogs demonstrated that doses of 0.6X the maximum exposure dose of Interceptor Plus, (1.5 mg/kg of milbemycin oxime), administered daily from mating through weaning, resulted in measurable concentrations of milbemycin oxime in milk. Puppies nursing these females demonstrated milbemycin oxime-related effects (depression, decreased activity, diarrhea, dehydration, nasal discharge). A subsequent study, which evaluated the daily administration of 0.6X the maximum exposure dose of Interceptor Plus, from mating until one week before weaning, demonstrated no effects on the pregnant females or their litters. A study, in which pregnant females were dosed once, at 0.6X the maximum exposure dose of Interceptor Plus before, on the day of, or shortly after whelping, resulted in no effects on the puppies.

Some nursing puppies, at 2, 4, and 6 weeks of age, administered oral doses of 9.6 mg/kg milbemycin oxime (3.8X the maximum exposure dose of Interceptor Plus) exhibited tremors, vocalization, and ataxia. These effects were all transient and puppies returned to normal within 24 to 48 hours. No effects were observed in puppies administered 0.5 mg/kg milbemycin oxime (minimum label dose).

A rising-dose safety study conducted in rough-coated Collies resulted in ataxia, pyrexia, and periodic recumbency in one of fourteen dogs administered milbemycin oxime at 12.5 mg/kg (5X the maximum exposure dose of Interceptor Plus). Prior to receiving the 12.5 mg/kg dose on day 56 of the study, all animals had undergone a dosing regimen consisting of 2.5 mg/kg milbemycin oxime on day 0, followed by 5.0 mg/kg on day 14, and 10.0 mg/kg on day 32. No adverse reactions were observed in any of the Collies treated with doses less than 12.5 mg/kg.

Storage:

Store at room temperature, between 59° and 77°F (15-25°C).

FAQ

Interceptor Plus is used for the prevention of heartworm disease caused by Dirofilaria immitis, and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina), adult hookworm (Ancylostoma caninum), adult whipworm (Trichuris vulpis) and adult tapeworm (Taenia pisiformis, Dipylidium canium, Echinococcus multilocularis and Echinococcus granulosus) infections in dogs and puppies over 6 weeks in age and weighing over 2 lbs. Prior to administration of Interceptor Plus (milbemycin oxime/praziquantel), dogs should be tested for existing heartworm infections.
Interceptor Plus should be administered orally, once every month, at the minimum dosage of 0.23 mg/lb (0.5 mg/kg) milbemycin oxime, and 2.28 mg/lb (5 mg/kg) praziquantel. For heartworm prevention, give once monthly for at least 6 months after exposure. Dogs weighing 2-8 lbs should be given one Interceptor Plus chewable tablet (Orange Box) monthly. Dogs weighing 8.1-25 lbs should be given one Interceptor Plus chewable tablet (Green Box) monthly. Dogs weighing 25.1-50 lbs should be given one Interceptor Plus chewable tablet (Yellow Box) monthly. Dogs weighing 50.1-100 lbs should be given one Interceptor Plus chewable tablet (Blue Box) monthly.
The following adverse reactions have been reported in dogs after administration of milbemycin oxime or praziquantel: vomiting, diarrhea, depression/lethargy, ataxia, weight loss, convulsions, weakness, and salivation.
Give the missed dose as soon as you remember. Do not give a double dose of the medication.
Contact your veterinarian immediately.
Do not give Interceptor to your pet if your pet is already taking an alternate heartworm medication.
Interceptor Plus should be administered in a manner that encourages your dog to chew, rather than swallow whole. However, we do not expect a difference in the effectiveness of the product if your dog consumes it whole.
You may maintain normal activities and interactions with your dog.

Interceptor Plus is indicated to treat and control intestinal parasite infections of adult hookworms, roundworms, whipworms and tapeworms.* In occasional cases, it is possible that the action of Interceptor Plus in killing the intestinal worms will lead to the dog expelling them in stool. If you have questions, consult your veterinarian for measures you can take to prevent a reinfection of intestinal parasites.

Hookworm (A. caninum), roundworm (T. canis, T. leonina), whipworm (T. vulpis) and tapeworm (T. pisiformis, E. multilocularis, E. granulosus and D. caninum)

Reviews

Review Summary
4.8
73 Reviews
5
86% (63)
4
12% (9)
3
1% (1)
2
0% (0)
1
0% (0)
100% Recommend this product (73 of 73 responses)
By Doddie
Alabama
Good price
September 7, 2023
Good price
none
By ANB
USA
Great Product
June 16, 2023
Entirely Pets is the BES!
In stock Price Reward Points Can't think of any
By ANB
somewhere in the USA
Great Service
May 11, 2023
Great team, had to call them three times to ask them to refax prescription, due to a problem at the Vet's office.
Great prices before the sales & proms & FABULOUS prices with sales & promos, plus you earn points.
Easy to order online, I am tech challenged, so trust me when I say this. Can't think of any
By Denise
Boise, Idaho
Customer service excellence
March 31, 2023
I received my purchase for a great price and in a timely manner, thanks!
By JimL
Hamilton, NY
Competitive price
March 30, 2023
Weā€™ve been buying Interceptor and Bravetco from Entirely Pets for the past several years because their prices are the best we could find. Always courteous and prompt.
Merchant Response:Hello Jim, We appreciate your feedback, EntirelyPets tries to offer all of our products at a competitive price, please keep an eye out on your email and the website for sales. Sincerely, EntirelyPets Pharmacy
By Charles
North Dartmouth, MA
love it
March 27, 2023
this is the most similar product to what i was using but the other brand smelled strange and my dog hated it. no issues with this one
Merchant Response:Hello Charles, We're glad to hear you are enjoying this product, we hope you continue to see improvements in your pet. Sincerely, EntirelyPets Pharmacy
By tracy b.
mission,texas
super service from caring people
March 10, 2023
great..........thank you very much for your considerable efforts getting my puppy dog, Buddy, his new brand of meds
tracy
Merchant Response:Hello Tracy, Thank you! Our pharmacy team works diligently to get all prescriptions approved and shipped as fast as possible. Sincerely, EntirelyPets Pharmacy
By Loretta
Columbus, OH
Excellent Product
December 14, 2022
I keep all my dogs on this year round. Price is great too
By Sean
Michigan
Excellent
September 15, 2022
Always pleased with the quick service and delivery. Customer service is excellent too. Repeat customer
By Fran
Massachusetts
GREAT PRICES AND FAST DELIVERY
August 22, 2022
Iā€™ve ordered from Entirely Pets several times and always with a good outcome. My Veterinarianā€™s office was closed awhile back and Entirely Pets didnā€™t give up until they received a prescription we needed. Most companies no longer care enough to put the effort in to get orders not this one. I would recommend them and will continue to order from them.
Merchant Response:Thank you for the kind words Fran. We do our best for you and your loved ones.
Always have what I need, coupons and shipping No cons for me
By Suzanne G.
Wantagh NY
Great service
July 21, 2022
Quick and easy
By Hannah
Caney, Kansas
Money Well Spent
March 9, 2022
I raise Golden Retrievers and Pembroke Corgis. I use Interceptor Plus for all of my adult dogs, and for all of my puppies starting at 8 weeks. It is always highly effective and I have never had any problems with it. I highly recommend using it.
By ANB
USA
Great Product
September 18, 2021
Interceptor Plus prevents Heart worms & controls round, hook, whip & tape worms. Dogs think it is a treat & eat it from my hand.
By luanne
Little Compton, RI
Dogs Hate Taste
August 6, 2021
The product is excellent, but both our dogs hate the taste. One dog will eat it if it's covered in peanut butter. With the other dog, we literally have to shove it down his throat and force him to eat it. I wish they would improve the taste.
taste
By Khusbu
Jersey City, NJ
Highly Recommend
June 27, 2021
I put my pup on this after a nightmare tapeworm incident while he was on a different heartworm preventative. Interceptor Plus covers a lot more than other brands, including tapeworms.
And my dog has a habit of eating random things during his walks. He's been doing well on interceptor plus.
By Don
Eastern Pennsylvania
Interceptor Plus
June 19, 2021
Vet recommended Interceptor Plus and Iā€™ve been using it for years. No issues or complaints. Apparently works as advertised.
Easy to administer. A bit pricey.
By Sue
NY
A+
June 18, 2021
First time using entirely pets The prices are great The communication is great you can actually reach people shipping was fast I will definitely be using them again
By Dolores F.
Alabama
The very best!
June 17, 2021
The very best!
By Pat
CT
Excellent product
April 24, 2021
This has worked well for all 3 of our dogs. We have noticed no side effects.
By Pat
Northeast
Works well for all of our dogs
April 24, 2021
Interceptor Plus has worked well for all 3 of our dogs. There have been no side effects in any o them.
By Tiffany
North Carolina
My picky dog loves it
April 21, 2021
My dog is very intuitive to whether she is getting a treat or ā€œmedicineā€ so when she took this the first time with no problem I was sold. Apparently it tastes good!
Easy to give Tastes good(not that I tried it)
By Judy G.
Wisconsin
Interceptor plus for dogs 50 to 100 lbs
March 26, 2021
What was ordered was fine, but took 4 phone calls to see where my order was. Ordered on 3/10 received 3/27. Will use again good prices and the people I dealt with were very nice and got things taken care of.
Merchant Response:Judy, we are working on our order visibility. Big improvements have been made and soon there will be a lot more visibility. A lot of upgrades happening on the back-end systems. Take care!
Good product and nice people
By Frank C.
PA
Excellent Product
January 28, 2021
Excellent Product
By Donna M.
New York
We Prefer It
January 2, 2021
We Prefer Interceptor plus because in addition to the heartworm, tapeworm, hookworm it also covers whip worms. We travel and had an incident where our dog came in contact with whip worms and wasn't using Interceptor Plus. She became sick with the worms and we had to make a stop at a local vet for help. Now we feel safer knowing that with Interceptor Plus our pets will be more protected and covered for Whip worms as well. Our dogs love the taste and eat it with no difficulty.
By Debbie
Louisiana
Great place to shop
January 1, 2021
Price was great and shipping was fast šŸ‘šŸ»
By RamboBlizzard
Albany, NY
Great to keep different types of worms away and cost effective
December 23, 2020
I love Interceptor Plus! We have been using it for years because it was one of the few heart worm medications that covered enough different types of worms to prevent our dogs from reoccurring intestinal worms. They are nice and healthy. The price point is good as well.
covers a wide range of worms
By Pet b.
WELD, ME
Great experience.
December 3, 2020
The meds are quickly processed and ship in great time. Also great price!
By KATHRYN S.
Girardville, PA
great product
November 25, 2020
my order was on time and exactly as described
By leslie h.
lebanon, ct
great place
November 15, 2020
easy web fast delivery
By Hali
Dayton, Ohio
Fast and priced right
October 19, 2020
Delivery with EntirelyPets is always fast and the price is so much better than getting the meds I need from my veterinarian. The process is very easy; they call my vet for the prescription right away, so there's no trouble getting what I need, when I need it.
Fast, reasonable costs, easy. None

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