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Comfortis is the first FDA-approved, chewable beef-flavored tablet (derived from pork protein and hydrolyzed soy) that kills fleas and prevents flea infestations on dogs and cats for a full month. Comfortis for Dogs & Cats requires a prescription from your veterinarian.
Comfortis kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis), for one month, on cats and kittens 14 weeks of age and older and 4.1 pounds of body weight or greater.
Comfortis for Dogs: 5-10 lbs - Comfortis for Cats: 4.1-6 lbs | |
---|---|
Active Ingredient (per tablet) | Amount |
Spinosad | 140 mg |
Comfortis for Dogs 10.1-20 lbs - Comfortis for Cats: 6.1-12 lbs | |
Active Ingredient (per tablet) | Amount |
Spinosad | 270 mg |
Comfortis for Dogs 20.1-40 lbs - Comfortis for Cats: 12.1-24 lbs | |
Active Ingredient (per tablet) | Amount |
Spinosad | 560 mg |
Comfortis for Dogs 40.1-60 lbs | |
Active Ingredient (per tablet) | Amount |
Spinosad | 810 mg |
Comfortis for Dogs 60.1-120 lb | |
Active Ingredient (per tablet) | Amount |
Spinosad | 1,620 mg |
View Comfortis Drug Facts Sheet.
Comfortis is given orally once a month, at the recommended minimum dosage of 13.5 mg/lb (30 mg/kg).
Do not use the dosing schedule below when administering Comfortis to cats, as it can result in an underdosage.
*Dogs over 120 lbs should be administered the appropriate combination of tablets.
Administer Comfortis with food for maximum effectiveness
Comfortis is a chewable tablet and is readily consumed by dogs when offered by the owner just prior to feeding. Alternatively, Comfortis may be offered in food or administered like other tablet medications. Comfortis should be administered at monthly intervals.
If vomiting occurs within an hour of administration, redose with another full dose. If a dose is missed, administer Comfortis with food and resume a monthly dosing schedule.
Treatment with Comfortis may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with Comfortis should continue the entire year without interruption.
To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product.
Comfortis is given orally once a month, at the minimum dosage of 22.5 mg/lb (50 mg/kg).
Do not use the dosing schedule below when administering Comfortis to dogs, as it can result in an overdosage.
*Cats over 24 lbs should be administered the appropriate combination of tablets.
Administer Comfortis with food for maximum effectiveness.
Comfortis is a chewable tablet that can be consumed by cats when offered by the owner just prior to or after feeding. Alternatively, Comfortis may be offered in food or administered like other tablet medications. Comfortis should be administered at monthly intervals
If vomiting occurs within an hour of administration, redose with another full dose. If a dose is missed, administer Comfortis with food and resume a monthly dosing schedule.
Treatment with Comfortis may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with Comfortis should continue the entire year without interruption.
To minimize the likelihood of flea reinfestations, it is important to treat all animals within a household with an approved flea protection product.
There are no known contraindications for the use of Comfortis.
Not for human use. Keep this and all drugs out of the reach of children.
Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with COMFORTIS (see Post Approval Experience)
Comfortis is for use in dogs and puppies 14 weeks of age and older (see Animal Safety).
Use with caution in breeding females (see Animal Safety). Use with caution in dogs with pre-existing epilepsy (see Adverse Reactions). The safe use of Comfortis in breeding males has not been evaluated.
Use with caution with concomitant extra-label use of ivermectin (see Adverse Reactions).
The safe use of Comfortis in breeding, pregnant, or lactating cats has not been evaluated.
Store at 20-25°C (68 -77°F), excursions permitted between 15 to 30°C (59 to 86°F).
In a well-controlled laboratory study, Comfortis began to kill fleas 30 minutes after administration and demonstrated 100% effectiveness within 4 hours. Comfortis kill fleas before they can lay eggs. If a severe environmental infestation exists, fleas may persist for a period of time after dose administration due to the emergence of adult fleas from pupae already in the environment. In field studies conducted in households with existing flea infestations of varying severity, flea reductions of 98.0% to 99.8% were observed over the course of 3 monthly treatments with Comfortis. Dogs with signs of flea allergy dermatitis showed improvement in erythema, papules, scaling, alopecia, dermatitis/pyodermatitis and pruritus as a direct result of eliminating the fleas.
Comfortis kills fleas before they can lay eggs when used monthly, according to the label directions. If you see fleas on your dog or cat within a month after your pet receives Comfortis, they are most likely new fleas. Because your pet has been treated with Comfortis, these new fleas will be killed before they can produce eggs that contaminate your home. Continued monthly use of Comfortis can prevent any new flea infestations.
Your pet can experience continued exposure to fleas living in the environment. It's important to treat all animals in the household with an approved flea product to help control the flea population. Learn more about controlling flea infestations in your home.
As with any medication, sometimes side effects occur. See the Comfortis label for complete safety information.
For cats: In some cases, cats vomited after receiving Comfortis. If vomiting occurs within one hour of administration, re-dose with another full dose. Additional adverse reactions observed in studies were lethargy, decreased appetite, weight loss, and diarrhea. Use with caution with concomitant extra-label use of ivermectin. See the Comfortis label for complete safety information.
For dogs: The most common adverse reaction reported is vomiting. Other adverse reactions reported in decreasing order of frequency are depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation and seizures. Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/drooling, seizures, ataxia, mydriasis, blindness, and disorientation. See the Comfortis label for complete safety information.
Your veterinarian is your pet's healthcare expert and can make the best medication recommendations. This includes the prevention, control and/or treatment of parasites such as fleas, heartworms and intestinal parasites. These parasites can cause conditions including flea allergy dermatitis, anemia, and heart disease. Key points of your discussion might include: