Comfortis for Dogs 60-120 lbs (Brown) - 12 Chew Tabs
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Comfortis for Dogs 60-120 lbs (Brown) - 12 Chew Tabs

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COMFORTIS chewable tablets (spinosad) are available in five chewable flavored tablet sizes for oral administration to dogs and puppies according to their weight. Each chewable tablet is formulated to provide a minimum spinosad dosage of 13.5 mg/Ib (30 mg/kg).

Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. Spinosyn A and spinosyn D have the chemical compositions 2-[(6-deoxy-2,3,4-tri-O-methyl-á-L-mannopyranosyl)oxy]-13-[[5-dimethylamino)-tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-9-ethyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-14-methyl-1 H-as-Indaceno[3,2-d]oxacyclododecin-7, 15-dione and 2-[(6-deoxy-2,3,4-tri-O-methyl-á-L-mannopyranosyl)oxy]-13-[[5-dimethylamino)-tetrahydro-6-methyl-2H-pyran-2-yl] oxy]-9-ethyl-2,3,3a,5a,5b,6,9,10,11,12,13,14, 16a,16b-tetradecahydro-4,14-dimethyl-1 H-as-Indaceno[3,2-d] oxacyclododecin-7,15-dione, respectively.

Indications:COMFORTIS chewable tablets kill fleas and are indicated for the prevention and treatment of flea infestations (Ctenocephalides felis) on dogs for one month.

Prescription Required


Dosage and Administration: COMFORTIS chewable tablets are given orally once a month, at the recommended minimum dosage of 13.5 mg/Ib (30 mg/kg).

Recommended Dosage Schedule:

Body Weight

Spinosad Per Tablet (mg)

Tablets Administered

3-5 lbs Dogs
2-4 lbs Cats



5-10 lbs Dogs
4-6 lbs Cats



10-20 lbs Dogs
6-12 lbs Cats



20-40 lbs Dogs
12-24 lbs Cats



40.1 to 60 Ibs



60.1 to 120* Ibs



* Dogs over 120 Ibs should be administered the appropriate combination of tablets.

Administer COMFORTIS chewable tablets with food for maximum effectiveness.

COMFORTIS is a chewable tablet and is readily consumed by dogs when offered by the owner just prior to feeding. Alternatively, COMFORTIS chewable tablets may be offered in food or administered like other tablet medications. COMFORTIS chewable tablets should be administered at monthly intervals.

If vomiting occurs within an hour of administration, redose with another full dose. If a dose is missed, administer COMFORTIS chewable tablets with food and resume a monthly dosing schedule.

Treatment with COMFORTIS chewable tablets may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with COMFORTIS chewable tablets should continue the entire year without interruption.

To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product.


16 Reviews
81% (13)
13% (2)
0% (0)
0% (0)
6% (1)
94% Recommend this product (15 of 16 responses)
By karla` sanjur
Miami, Florida
October 19, 2018
Works great
Always kills fleas within 30 minutes. Service was great and delivery on time.
By Katrina
Oregon Coast
October 17, 2018
Good Value
Easiest way to buy and a great price.
By Lu Ann Hergenrader
August 29, 2018
Recent order
First time using - great service - contacted my vet for a prescription right away and product arrived very soon after - will use again.
By spex
fountain valley , Ca.
May 18, 2018
I got it !
it was a little faster receiving the comfortis, and sale price was a bonus. I was pleased all around. It is easier to administer to my pet.
ProsEasier to give to my pet.
San Diego, California
March 17, 2018
Stomach Upset
I provided the ComFortis tablet immediately following our dog’s breakfast. He vomited everything up within the hour. Gastrointestinal issues are not typical with our dog.
ConsStomach upset.
By Ella Phillips
San Diego, California
January 18, 2018
Comfortis for Dogs
Very pleased with the service received. There were no discrepancies with the product, or with the order. The customer service was excellent and quite comforting. I would suggest that Entirely Pets is used for all of your pet needs.
Merchant Response:Thank you for your kind words Ella! Glad we are able to help!
ProsGood prices, order in a timely manner!
ConsNo complaints!
By Orange co mom
Huntington Beach California
October 5, 2017
Great product
The time it took to get the actual product was too long but the product itself and the price was great.
ConsTook too long
By Shelley
St. Louis, MO
October 4, 2017
Comfortis for dogs
good value, best price I could find
By Barcomb, Lowell
Houston, Tx
April 23, 2017
Great product
Product works great. No live fleas found on my dog
No scratching.
Happy dog, đŸ•
By pepperoni
san diego, California
April 17, 2016
Really effective; if only it weren't chewable
Great product but both dogs detest the flavor. So I'm left with huge pills I can't even disguise in food and it's the only medication I have to shove down their throats. Comfortis: PLEASE make a small pill that isn't chewable.
Consdogs hate the taste and it's so strong I can't even disguise it covering it with blue cheese!
By holly
Old Fort, NC
April 4, 2016
works great!
I have used this product on my cats. it works really really well and I like it much better than the topical. I hate that stuff. they sleep in my bed and the thought of that getting wiped everywhere freaks me out. the pills are easy, not messy, and really work!!! although I haven't ordered from entirely pets yet, I am planning on using them for my next order because their prices a MUCH less than at the vet!
Prosworks great, no mess, better prices than the vet
By Vicky
McKinlyville CA
March 5, 2016
Finally NO FLEAs!
yĂ y...this product actually works! I've spent hundreds of dollars trying to get the fleas off our GermĂ n Shepherd. For yearrs he would mĂ ke himself, Ă nd me, crazy and hairless from scratching at them. After 2 months, his hair is growing back now and he looks really nice and shiny and happy!! SSo glad I switched from topicals!
By Gary L
Surf City, USA
August 26, 2015
Good price...same product as from my vet
Easy transaction. Simple and quick. Only delay was getting prescription from my own vet. Not Entirely Pet's problem. They fax'ed request to my vet. Once received from vet, shipped to me.
ProsGood price Easy transaction
ConsDelay in securing prescription from my vet
By Gary L
Surf City, USA
August 23, 2015
Same as what I get at my vet
Same product sold by my vet at a higher price that was prescribed for my dog. Easy online transaction.
ProsGood Price Works for my dog
ConsTook awhile for my vet to approve the prescription for my dog. Not Entirely Pets' problem as they fax'ed request to vet right after receiving order. I had to follow up with vet to make sure they responded to Entirely Pets' request.
By Jean
Topeka, Kansas
July 9, 2015
Most reasonable deal found
I did a lot of research and found purchasing Comfortis from Entirely Pets Pharmacy was the best deal. Thanks - I always believe in saving money.
By Karen
Ventura County, Ca
June 21, 2015
Requested Comfortis. Provided my vet's name and fax #. EntirelyPets did the rest.