Vitamin K1 Inj 10mg/ml (100 ml)

Vitamin K1 intended for use in cats, dogs, goats, sheep, swine, horses, calves, and cattle. It is used for countering hypoprothrombinemia caused by ingesting compounds that are coumarin-based typically used in rodenticides for commercial use.

Key Benefits

• Suitable for parenteral administration to domestic animals and livestock
• Convenient pack size
• Short withholds for livestock
• An aqueous colloidal solution
• Treats domestic animals exposed to poisoning by Warfarin or other coumarins

How It Works

After administering this medication intramuscularly, phytonadione is absorbed readily. Following this absorption, initial concentration of phytonadione is primarily in the liver. This rapidly declines and vitamin K does not accumulate in tissues of the body.

Indications

Vitamin K1 Injection is indicated in the treatment of hypoprothrombinaemia associated with poisoning by warfarin or other coumarins

View Vitamin K1 Drug Facts Sheet.

To be administered by intramuscular, subcutaneous or slow intravenous injection.

• Dogs & Cats 0.25 - 2.5mg/kg bodyweight.
• Large animals 0.5 - 2.5mg/kg bodyweight.

Daily dosing should continue for four days. In severe cases of anaemia the dosage may be increased to 5mg/kg bodyweight for 4 days followed by oral Vitamin K1 therapy.

Contraindications, Warnings, Etc

For animal treatment only.

Not to be used in animals known to be hypersensitive to the active ingredient.

Anaphylactoid and other hypersensitivity reactions may occur following intravenous administration. Fatalities have occurred with products of this kind although it is unclear whether these reactions were caused by phytomenadione itself or by surfactants included in the formulation.

Pain and swelling may occur at injection sites following administration of Phytomenadione.

Intravenous injections should be given slowly (ie over 30 - 40 seconds).

Acute haemorrhage may also require transfusion therapy. Phytomenadione will not counteract the anticoagulant action of heparin.

Withrawal Periods

Milk:

Milk intended for human consumption must not be taken from a cow during treatment. Milk for human consumption may be taken only after 7 days from the last treatment.

Meat:

Animals intended for human consumption should not be slaughtered during treatment.

Animals for human consumption may be slaughtered for human consumption only after 28 days from the last treatment.

Interaction with other medicaments and other forms of interaction

As Vitamin K1 possibly acts by competitive antagonism of coumarins, the efficacy of Vitamin K1 will be reduced by continued dosage of coumarins.

Pharmaceutical Precautions

For animal treatment only. Keep out of reach and sight of children. Do not store above 25°C and protect from light. Do not allow the injection to freeze. If separation has occurred or if oil droplets have appeared, the injection should not be used. Avoid the introduction of contamination during use. Should any apparent growth or discoloration occur the product should be discarded.