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Vetoryl (Trilostane) 10 mg (30 caps)

Item# IWM035163
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Recurring Saings in EprxAUTOSHIP & SAVE[Details]
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  • Description
  • Ingredients
  • Directions
  • FAQ
  • Reviews


Vetoryl Capsules 10 mg are an FDA-Approved solution used to treat dogs with pituitary-dependent and adrenocortical tumor-dependent hyperadrenocorticism. Hyperadrenocorticism is also commonly known as Cushing's Disease.

Key Benefits

  • Improvement seen within several weeks
  • Available in 5 mg, 10 mg, 30 mg, 60 mg, or 120 mg capsules (based on weight)
  • FDA-Approved

How It Works

Vetoryl uses a chemical (Trilostane) that controls the adrenal gland's excess production of cortisol, a hormone released into the bloodstream during times of stress.


Do not give this medication to dogs with kidney or liver disease. Vetoryl capsules should not be given to dogs taking certain medications or dogs that are pregnant. Speak with your veterinarian about all medications your dog is taking, including over-the-counter medicines.

prescription required symbol

NDC 17033-105-30

NADA 141-291


Active Ingredient: Trilostane


Give this medication exactly as directed by your veterinarian.Wash your hands after use. Do not handle the capsules if you are pregnant or trying to become pregnant. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you.

View Vetoryl package insert for more information.

Dosage & Administration

  • Administer 1 capsule of appropriate concentration for your dog's weight (see table below)
  • Give this medication with food
  • Concentrations may be mixed to achieve the correct dose for your dog

Quick Tips

  • Vetoryl is used to treat dogs with hyperadrenocorticism, also known as Cushing's Disease.
  • Vetoryl capsules should be given with food.
  • Do not open capsules and do not attempt to split or divide capsule.

Dosage Table

3.8 to 10 lbsOne 10 mg capsule daily
10 to 22 lbsOne 30 mg capsule daily
22 to 44 lbsOne 60 mg capsule daily
44 to 88 lbsOne 120 mg capsule daily
88 to 132 lbsOne 120 mg capsule of 120 mg and one 60 mg capsule daily (180 mg total)
Over 132 lbsAdminister the appropriate amount of capsules based on dog's weight. Speak with your veterinarian to help you determine the correct dosage for your dog.

Storage Directions

Store at room temperature 25°C (77°F) with excursions between 15°- 30°C (59°- 86°F) permitted. Keep out of reach of children and pets.

Human Warnings

Keep out of reach of children. Not for human use.

Wash hands after use. Do not empty capsule contents and do not attempt to divide the capsules. Do not handle the capsules if pregnant or if trying to conceive. Trilostane is associated with teratogenic effects and early pregnancy loss in laboratory animals. In the event of accidental ingestion/overdose, seek medical advice immediately and take the labeled container with you.


The use of Vetoryl Capsules is contraindicated in dogs that have demonstrated hypersensitivity to trilostane. Do not use Vetoryl Capsules in animals with primary hepatic disease or renal insufficiency . Do not use in pregnant dogs. Studies conducted with trilostane in laboratory animals have shown teratogenic effects and early pregnancy loss.

Possible Side Effects

If any of the following serious side effects occur, stop giving Vetoryl and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face; hives), severe depression, bloody diarrhea, collapse, or other severe reactions. Other less serious side effects such as unexpected decrease in appetite, vomiting, diarrhea, and lethargy may occur. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your dog.


Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not give a double dose of the medication.
Seek emergency veterinary medical treatment. Symptoms of Vetoryl overdose may include lethargy, weakness, vomiting, or collapse.
Do not give Vetoryl to dogs with kidney or liver disease. Do not give to pregnant or nursing dogs or dogs intended for breeding. Do not touch Vetoryl capsules if you are pregnant or trying to become pregnant.
Before giving Vetoryl tell your veterinarian if your pet is also taking ACE inhibitors such as enalapril, potassium sparing diuretics such as spironolactone, ketoconazole, or potassium supplements. Talk to your veterinarian or pharmacist before giving any prescription or over the counter medicines or nutritional supplements.
Tell your veterinarian if your pet has kidney or liver disease. Tell your veterinarian about any other medical problems or allergies your dog has now or has had in the past. Tell your veterinarian about any medications your dog is taking including over the counter products and nutritional supplements. Tell your veterinarian if your pet is pregnant, nursing, or if you plan to breed your dog.


Review Summary
10 Reviews
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100% Recommend this product (10 of 10 responses)
By Kathryn
The Villages FL
Order online Pet supplies
March 7, 2021
Once I got the prescription details worked out as my Vet would not email RX, my order was here overnight. It was exactly what I ordered and the price was so much more reasonable. As I have aging dogs plan to use Entirely for all future needs.
By Curtis
Beverly Hills, California
Great price for brandname product
May 4, 2020
This is the real brand name product for pets with Cushings Disease. Mine could not live without it and I appreciate the great pricing EntirelyPets Pharmacy offers consistently!
  • price, availability
By Kelly
Review of Entirely Pets Pharmacy
October 15, 2018
This is my second order through this company. The first order did not go smoothly but after a phone call to the company, they got everything cleaned up and taken care of right away. The second order went like clockwork, and I received my order that same week.
  • Pleased with the efficiency in which your office handles the orders, customer service reps were kind and knowledgable.
  • So far, none. I am happy with the service I have received thus far.
By Lacie
Helps with Cushings
September 6, 2018
My vet prescribed this for my 11 year old Boston Terrier who has Cushings Disease. It helps with the symptoms (thirst, stress & excessive urination). It does make my dog very sleep though.

I give my Boston Terrier Vetoryl along with some natural supplements: Milk Thistle Blend (liver & kidney protection), Flaxseed Lignans, and Melatonin. I must say that my dog's fur was patchy and horrible (even when on Vetoryl) until I added Melatonin to her regimen. The melatonin grew her fur back beautifully, the best it's ever been!

I searched all over the internet and found that Entirely Pets Pharmacy has the best price for Vetoryl. Ordering online is easy and fast. I've been ordering from them more than a year now.

Merchant Response:Lacie, We are ecstatic to find your Boston Terrier with Cushings Disease has come a long way with Vetoryl and your additional supplements. We can tell you are a good pet parent and we are happy to have you as a customer. Sincerely All of us at EntirelyPets Pharmacy. PS, that photo is adorable!
By Charles S.
Fresno, CA
Our experience
May 11, 2018
The product is good and now that I received suggestions from the staff my ordering experience should be a lot better.

Once a customer sets up their account and gets the prescription on file the best method to not have worries and get the order placed and delivered it was suggested that I call the order in and not use the online ordering method. Simply put when you order online the order goes into a "pile" and does not get handled until your place comes up. When you order by phone you may have to wait a bit to get someone on the line but your order is received, handled, and all should go smooth.

Hope this helps to all.
By Jim
Chicago, Illinois
Dog Medication
May 6, 2018
We were running low on our dog’s medication and found in third instance that Entirely Pets Pharmacy offered it at a considerably lower price. We ordered it and were happy to see it arrive in less than a week.
  • The price was much lower than all competitors.
  • We never knew when the medication would arrive as delivery times for the same item varied in the past. This often caused concern we would run out of medicine before a new supply would arrive.
Right product. Right price
April 14, 2018
I spent years paying so much more for the same product my dog needs.
By marissa
bonita, CA
Best price
December 22, 2017
I like that I don't have to drive 45 minutes one way each month to pick meds up at twice the price!
  • Excellent customer service.
  • Used auto ship every 4 weeks but haven't received yet!
By M S.
Sacramento, CA
November 24, 2017
My dog as lived with cushings the last 4 years. Its well under control. Entirely Pets Pharmacy is a efficient and cost savings way to order my pets prescriptions on line.
Merchant Response:So glad to hear you're able to keep your dog's cushings under control with the Veotryl, also glad we could help save you money by doing so ;)
By Nancy
May 1, 2017
Prescribed item from the vet but only cheaper at Entirely Pets Pharmacy.
Merchant Response:Thank you for your feedback Nancy, glad we were able to work together and help you save money!

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