Terramycin for Animals - (3.5 gram) - [Antibiotic]

Terramycin (Oxytetracycline Hydrochloride and Polymyxin B Sulfate) is a broad-spectrum ophthalmic antibiotic ointment formulated to treat a wide range of eye infections in dogs, cats, cattle, sheep, and horses. This bright yellow ointment delivers potent antimicrobial activity against gram-positive and gram-negative bacteria, including aerobic and anaerobic species, spirochetes, rickettsiae, and some larger viruses.

Oxytetracycline hydrochloride is a versatile antibiotic that inhibits bacterial protein synthesis, while Polymyxin B sulfate, derived from Bacillus polymyxa, is rapidly bactericidal against gram-negative organisms—especially Pseudomonas aeruginosa—and may offer additional antifungal benefits. Together, these ingredients offer additive or synergistic antibacterial effects.

This ophthalmic preparation is formulated in a special petrolatum base for optimal ocular absorption and ease of application. Each gram contains 5 mg of oxytetracycline HCl and 10,000 units of polymyxin B sulfate.

Key Benefits

• Broad-spectrum antibiotic action with synergistic dual ingredients
• Effective against both primary and secondary eye infections in pets
• Treats conjunctivitis, keratitis, corneal ulcers, and pink eye
• Useful in managing Chlamydia-related eye infections in cats
• Suitable for use in dogs, cats, horses, cattle, and sheep

How It Works

Oxytetracycline inhibits bacterial protein synthesis, preventing growth and replication. Polymyxin B disrupts the bacterial cell membrane, causing rapid death of susceptible gram-negative bacteria. Their combined action maximizes effectiveness across a wide range of pathogens.

Indications

Terramycin Ophthalmic Ointment is indicated for the prophylaxis and treatment of superficial ocular infections caused by oxytetracycline- and polymyxin-sensitive organisms. Conditions include:

• Conjunctivitis
• Keratitis
• Corneal ulcers
• Blepharitis
• Pink eye
• Secondary bacterial complications of distemper in dogs
• Bacterial eye inflammation due to other infectious diseases

Effective in dogs, cats, cattle, sheep, and horses.

Active Ingredients:

• Oxytetracycline Hydrochloride: Equivalent to 5 mg of oxytetracycline per gram of ointment
• Polymyxin B Sulfate: 10,000 units per gram of ointment

Inactive Ingredients:

• Petrolatum base
• Mineral oil (may be included depending on formulation)

View the Terramycin Drug Facts Sheet (PDF)

Terramycin Ophthalmic Ointment (Oxytetracycline Hydrochloride and Polymyxin B Sulfate) is for topical use in the eyes of dogs, cats, cattle, sheep, and horses. Apply directly to the affected eye(s) 2–4 times daily or as directed by your veterinarian.

Caution:

• Do not allow the tip of the tube to touch any surface, including eyes, hands, or other objects.
• This medication may temporarily blur vision following application.
• Do not use other eye medications unless prescribed or approved by your veterinarian.
• Prolonged use may lead to secondary bacterial or fungal infections.

Warning:

Hypersensitivity Warning (Cats): Serious and potentially life-threatening allergic reactions have been reported in cats after using antibiotic ophthalmic medications. If your cat shows any of the following symptoms within 4 hours of application, discontinue use and contact your veterinarian immediately:

• Facial swelling
• Itching or scratching
• Vomiting
• Weakness or lethargy
• Difficulty breathing

Note:

The use of oxytetracycline or similar antibiotics can occasionally result in overgrowth of resistant organisms such as Monilia, staphylococci, or other bacteria and fungi. If signs of a new infection appear during treatment, discontinue use and consult your veterinarian for alternative therapy.

Storage Instructions:

Store Terramycin Ointment at controlled room temperature between 20°C to 25°C (68°F to 77°F). Permissible temperature excursions are 15°C to 30°C (59°F to 86°F). Keep out of reach of children and pets.