This summary contains important information about Firocoxib Tablets for Horses. You should read this information before you start giving your horse Firocoxib Tablets for Horses and review it each time your prescription is refilled. This sheet is provided only as a summary and does not take the place of instructions from your veterinarian. Talk to your veterinarian if you need clarification, have questions, or you want to know more about Firocoxib Tablets for Horses.
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PRN Firocoxib Tablets for Horses, 57-mg, 60 count
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- Description
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- FAQ
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Description
PRN Firocoxib Tablets for Horses is a veterinary prescription nonsteroidal anti-inflammatory drug (NSAID) of the coxib class used to control pain and inflammation associated with osteoarthritis in horses. Osteoarthritis (OA) is a painful condition caused by progressive "wear and tear" of cartilage and other parts of the joints that may result in the following changes or signs in your horse:
- Limping or lameness.
- Decreased activity or exercise (reluctance to stand, walk, trot or run, or difficulty performing these activities).
- Stiffness or decreased movement of joints.
Indications
Firocoxib Tablets for Horses are administered once daily for up to 14 days for the control of pain and inflammation associated with osteoarthritis in horses.
Directions
Always provide the Client Information Sheet with the prescription. The recommended dosage of Firocoxib Tablets for Horses is one 57 mg tablet administered orally to horses weighing 800 - 1300 lbs, once daily for up to 14 days. For ease of administration, Tablets for Horses may be given with food.
The overall duration of treatment with any firocoxib formulation in horses, including tablets, injection or oral paste should not exceed 14 days. Please see the package insert for firocoxib injection or oral paste for appropriate prescribing information for those fonnulations.
Contraindications:
Horses with a hypersensitivity to firocoxib should not receive Firocoxib Tablets for Horses.
Warnings:
For use in horses only. Do not use in horses intended for human consumption. Store Firocoxib Tablets for Horses out of the reach of dogs and other pets in a secured location in order to prevent ingestion or overdose.
Human Warnings:
Not for use in humans. Keep this and all medications out of the reach of chil- dren. Consult a physician in case of accidental ingestion by humans.
Precatuions:
Horses should undergo a thorough history and examination before initiation of NSAID therapy. Appropriate laboratory tests should be conducted to establish hematological and serum biochemical baseline data before and periodically during administration of any NSAID. Clients should be advised to observe for signs of potential drug toxicity and be given a Client Information Sheet with each prescription. See Information for Owner or Person Treating Horse section of this package insert.
Treatment with Firocoxib Tablets for Horses should be terminated if signs such as inappetence, colic, abnonnal feces, or lethargy are observed.
As a class, cyclooxygenase inhibitory NSAIDs may be associated with gastrointestinal, renal, and hepatic toxicity. Sensitivity to drug-associated adverse events varies with the individual patient. Horses that have experienced adverse reactions from one NSAID may experience adverse reactions from another NSAID. Patients at greatest risk for adverse events are those that are dehydrated, on diuretic therapy, or those with existing renal, cardiovascular, and/or hepatic dysfunction. Concurrent administration of potentially nephrotoxic drugs should be carefully approached or avoided. NSAIDs may inhibit the prostaglandins that maintain normal homeostatic function. Such anti-prostaglandin effects may result in clinically significant disease in patients with underlying or pre-existing disease that has not been previously diagnosed. Since many NSAIDs possess the to produce gastrointestinal ulcerations and/ or gastrointestinal perforation, concomitant use of Firocoxib Tablets for Horses with other inflammatory drugs, such as NSAIDs or should be avoided.
The concomitant use of protein bound drugs with Firocoxib Tablets for Horses has not been studied in horses. The influence of concomitant drugs that may inhibit the metabolism of Firocoxib Tablets for Horses has not been evaluated. Drug compatibility should be monitored in patients requiring adjunctive therapy.
The safe use of Firocoxib Tablets for Horses in horses less than one year in age, horses used for breeding, or in pregnant or lactating mares has not been evaluated.
Consider appropriate washout times when switching from one NSAID to another NSAID or corticosteroid.
FAQ
Firocoxib Tablets for Horses should be given according to your veterinarian's instructions. Do not change the way you give Firocoxib Tablets for Horses to your horse without first speaking with your veterinarian. Do not exceed 14 days of treatment.
Firocoxib Tablets for Horses may be given with or without food. Do not give firocoxib chewable tablets for dogs to horses, as overdoses may occur and result in serious side effects.
While Firocoxib Tablets for Horses are not a cure for osteoarthritis, it can control the pain and inflammation associated with OA and can improve your horse’s mobility.
Your horse should not be given Firocoxib Tablets for Horses if he/she:
- Has an allergic reaction to firocoxib, the active ingredient in Firocoxib Tablets for Horses.
- Has previously had an allergic reaction (such as hives, facial or lower limb swelling, or red or itchy skin) to aspirin or other NSAIDs.
- Is presently taking aspirin, phenylbutazone, flunixin meglumine, diclofenac, ketoprofen, or other NSAIDs or corticosteroids.
- The safety of Firocoxib Tablets for Horses has not been determined in horses less than one year of age or in breeding horses, pregnant or lactating mares.
- Firocoxib Tablets for Horses is not for use in horses intended for human food consumption.
- People should not take Firocoxib Tablets for Horses. Keep Firocoxib Tablets for Horses and all medications out of the reach of children. Consult a physician in case of accidental ingestion by humans.
- Store Firocoxib Tablets for Horses out of reach of dogs and other pets in a secured location in order to prevent accidental ingestion or overdose.
Talk to your veterinarian about:
- The signs of OA you have observed in your horse, such as limping or stiffness.
- If any tests, such as X-rays, will be done before Firocoxib Tablets for Horses is prescribed.
- How often your horse may need to be examined by your veterinarian.
- The risks and benefits of using Firocoxib Tablets for Horses.
Tell your veterinarian if your horse has ever had the following medical problems:
- Any side effects from taking Firocoxib Tablets for Horses or other NSAIDs, such as aspirin or phenylbutazone.
- Any kidney disease.
- Any liver disease.
- Any gastrointestinal ulcer.
Tell your veterinarian about:
- Other medical problems or allergies that your horse has now or has had in the past.
- All medicines that you are giving or plan to give to your horse, including those you can get without a prescription and any dietary supplements.
Tell your veterinarian if you plan to breed your horse, or if your mare is pregnant or nursing a foal.
Firocoxib Tablets for Horses, like other NSAIDS, may cause some side effects. Serious side effects associated with NSAID therapy in horses can occur with or without warning. The most common side effects associated with Firocoxib Tablets for Horses therapy involve the tongue, lips and skin of the mouth and face (erosions and ulcers of the mucosa and skin) and the kidney. Gastrointestinal, kidney and liver problems have also been reported with other NSAIDs. Look for the following side effects that may indicate your horse is having a problem with Firocoxib Tablets for Horses or may have another medical problem:
- Sores or ulcers on the tongue and inside of mouth.
- Sores, scabs, redness, or rubbing of the facial skin, particularly around the mouth.
- Change in eating or drinking habits (frequency or amount consumed).
- Change in urination habits (frequency or color).
- Yellowing of gums, skin, or whites of the eyes (jaundice).
- Unexpected weight loss.
- Change in behavior (such as increased or decreased activity level).
It is important to stop therapy and contact your veterinarian if you think your horse has a medical problem or side effect while taking Firocoxib Tablets for Horses. If you have additional questions about possible side effects, talk with your veterinarian or call 1-800-874-9764.
Firocoxib Tablets for Horses should not be given with other NSAIDs (for example, aspirin, phenylbutazone, diclofenac, ketoprofen or flunixin) or systemic corticosteroids (for example, prednisone, cortisone, dexamethasone, or triamcinolone).
Tell your veterinarian about all medications that you have given your horse in the past, and any medications you are planning to give with Firocoxib Tablets for Horses. This should include other medicines that you can get without a prescription or any dietary supplements. Your veterinarian may want to check that all of your horse’s medicines can be given together.
Consult your veterinarian if your horse receives more than the prescribed amount of Firocoxib Tablets for Horses.
- This sheet provides a summary of information about Firocoxib Tablets for Horses and general information about NSAIDs. If you have any questions or concerns about Firocoxib Tablets for Horses or osteoarthritis pain, talk with your veterinarian.
- As with all prescribed medicines, Firocoxib Tablets for Horses should only be given to the horse for which it is prescribed. It should be given to your horse only for the condition for which it is prescribed, at the labeled dose and duration.
- It is important to periodically discuss your horse's response to Firocoxib Tablets for Horses. Your veterinarian will determine if your horse is responding as expected and if your horse should continue receiving Firocoxib Tablets for Horses.
