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Firocoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in dogs to treat pain and inflammation associated with osteoarthritis. It is available as a chewable tablet and is effective in reducing inflammation and pain for up to 24 hours. Firocoxib works by inhibiting the activity of an enzyme called cyclooxygenase-2 (COX-2), which plays a key role in the production of inflammatory molecules in the body. It is important to follow the recommended dosage and administration instructions provided by a veterinarian when giving firocoxib to a dog to minimize potential side effects and ensure safety. Common side effects of firocoxib may include vomiting, diarrhea, decreased appetite, and lethargy, and in rare cases, serious adverse effects such as gastrointestinal ulcers, liver damage, or kidney failure may occur. It is essential to consult with a veterinarian before starting any new medication for a pet.
Firocoxib chewable tablets are indicated for the following conditions in dogs:
It is important to note that Firocoxib should only be used under the guidance and prescription of a veterinarian. They will assess the specific condition of the dog and determine if Firocoxib is the appropriate treatment option.
Firocoxib belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Specifically, it is a selective cyclooxygenase-2 (COX-2) inhibitor. COX-2 is an enzyme that plays a key role in the production of prostaglandins, which are responsible for causing pain, fever, and inflammation.
By inhibiting COX-2, Firocoxib reduces the production of prostaglandins, which helps to alleviate pain and inflammation associated with conditions like osteoarthritis and post-operative pain. Importantly, Firocoxib has a lower risk of gastrointestinal, renal, and liver side effects compared to other NSAIDs due to its selectivity for COX-2.
It is important to note that the exact mechanism of action of Firocoxib is not fully understood, and it is recommended to only be used under the guidance and prescription of a veterinarian.
Always provide the Client Information Sheet with prescription. Carefully consider the potential benefits and risks of Firocoxib Chewable Tablets for Dogs and other treatment options before deciding to use Firocoxib Chewable Tablets for Dogs. Use the lowest effective dose for the shortest duration consistent with individual response. The recommended dosage of Firocoxib Chewable Tablets for Dogs for oral administration in dogs is 2.27 mg/lb (5.0 mg/kg) body weight once daily as needed for osteoarthritis and for 3 days as needed for postoperative pain and inflammation associated with soft-tissue and orthopedic surgery. The dogs can be treated with Firocoxib Chewable Tablets for Dogs approximately two hours prior to surgery. The tablets are scored and dosage should be calculated in half tablet increments. Firocoxib Chewable tablets for Dogs can be administered with or without food.
Dogs with known hypersensitivity for firocoxib should not receive Firocoxib Chewable Tablets for Dogs.
Not for use in humans. Keep this and all medications out of the reach of children. Consult a physician in case of accidental ingestion by humans.
Keep Firocoxib Chewable Tablets for Dogs in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.
For oral use in dogs only. Use of this product at doses above the recommended 2.27 mg/lb (5.0 mg/kg) in puppies less than seven months of age has been associated with serious adverse reactions, including death. Due to tablet sizes and scoring, dogs weighing less than 12.5 lb (5.7 kg) cannot be accurately dose.
All dogs should undergo a thorough history and physical examination before the initiation of NSAID therapy. Appropriate laboratory testing to establish hematological and serum baseline data is recommended prior to and periodically during administration of any NSAID.
Owners should be advised to observe for signs of potential drug toxicity and be given a Client Information Sheet about Firocoxib Chewable Tablets for Dogs.