Phenylbutazone for Horses - [Bute] 20% Injection 200mg/ml (100 ml) - [Pain & Inflammation Relief] | On Sale | EntirelyPets Rx
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Phenylbutazone for Horses - [Bute] 20% Injection 200mg/ml (100 ml) - [Pain & Inflammation Relief]

Phenylbutazone for Horses - [Bute] 20% Injection 200mg/ml (100 ml) - [Pain & Inflammation Relief]

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Description

Phenylbutazone is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with fractures, arthritis, and painful injuries to the limbs and joints. Phenylbutazone requires a prescription from your veterinarian, and is available by the tablet, in an injectable solution, and as an oral paste. Phenylbutazone injectable solution must be kept in the refrigerator at all times. To ensure proper temperature, Phenylbutazone injectable solution requires overnight shipping at an additional cost.

Key Benefits

  • Relieves pain and inflammation
  • Particularly good for osteoarthritis
  • Reduces fever

How It Works

Phenylbutazone is a non-steroidal anti-inflammatory drug (NSAID) which through its anti-inflammatory action can relieve pain, reduce inflammation and reduce fever.

Indications

For relief of inflammatory conditions associated with the musculoskeletal system in horses.

Directions

Intravenously:

1 to 2 g per 1,000 lbs of body weight (5 to 10 mL/1,000 lbs) daily. Injection should be given slowly and with care. Limit intravenous administration to a maximum of 5 successive days, which may be followed by oral phenylbutazone dosage forms.

Guidelines to Successful Theraphy

  1. Use a relatively high dose for the first 48 hours, then reduce gradually to a maintenance dose. Maintain lowest dose capable of producing desired clinical response.
  2. Response to phenylbutazone therapy is prompt, usually occurring within 24 hours. If no significant clinical response is evident after 5 days, reevaluate diagnosis and therapeutic approach.
  3. In animals, phenylbutazone is largely metabolized in 8 hours. It is recommended that a third of the daily dose be administered at 8 hour intervals. Reduce dosage as symptoms regress. In some cases, treatment may be given only when symptoms appear with no need for continuous medication. If long-term therapy is planned, oral administration is suggested.
  4. Many chronic conditions will respond to phenylbutazone therapy, but discontinuance of treatment may result in recurrence of symptoms.

Caution:

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Contraindications:

Treated animals should not be slaughtered for food purposes. Parenteral injections should be made intravenously only; do not inject subcutaneously or intramuscularly. Use with caution in patients who have a history of drug allergy.

Precautions:

Stop medication at the first sign of gastrointestinal upset, jaundice, or blood dyscrasia. Authenticated cases of agranulocytosis associated with the drug have occurred in man. To guard against this possibility, conduct routine blood counts at weekly intervals during the early phase of therapy and at intervals of two weeks thereafter. Any significant fall in the total white count, relative decrease in granulocytes, or black or tarry stools, should be regarded as a signal for immediate cessation of therapy and institution of appropriate counter measures. In the treatment of inflammatory conditions associated with infections, specific anti-infective therapy is required.

Storage:

Store in a refrigerator between 2°C - 8°C (36°F - 46°F).

FAQ

Phenylbutazone is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with fractures, arthritis and painful injuries to the limbs and joints. Phenylbutazone may be used for purposes other than those listed in this medication guide.
Tell your veterinarian if your horse has ever had an allergic reaction to phenylbutazone or any other NSAID. Tell your veterinarian if your horse has any liver, kidney or heart disease. Tell your veterinarian if your horse is pregnant or lactating. Talk to your veterinarian about the appropriate syringe to use with Phenylbutazone Injectable Solution.
Give this medication exactly as directed by your veterinarian. If you do not understand the directions, ask your pharmacist or veterinarian to explain them to you. Tablets should be given with food. Phenylbutazone injectable solution should be administered intravenously. Store this medication at room temperature. Keep out of the reach of children and pets.
Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and give the next one as directed. Do not give a double dose of the medication.
In the event of overdose, contact your veterinarian or veterinary emergency room. Symptoms of overdose may include decreased urine production and blood in the urine, jaundice (yellowing of the skin, gums and eyes), pale gums, weakness, and ulcers.
Do not use phenylbutazone in animals allergic to it or other NSAIDs. Do not use in pregnant or lactating mares. Do not give phenylbutazone with other NSAIDs, corticosteroids, or other ulcer causing medications.
Side effects that may occur when using phenylbutazone may include ulcers, kidney damage, bloody stool, decreased white blood cells and platelets as well as an allergic reaction (facial swelling, hives, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, coma). Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your horse.
Use caution when giving phenylbutazone with phenytoin, warfarin, sulfonamides, glipizide, digoxin, barbiturates, rifampin, chlorpheniramine or diphenhydramine. Talk to your veterinarian or pharmacist before using phenylbutazone with any prescription or over the counter medications, including vitamins, minerals and herbal supplements.
Your pharmacist has additional information about phenylbutazone written for health professionals that you may read.

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