Neomycin for Dogs & Cats -, Polymyxin B Sulfates and Gramicidin Ophthalmic Solution 10 mL (Manufacturer may vary) - [Eye Health]

Neo-Poly Gramicidin Ophthalmic Solution is a triple antibiotic used by veterinarians to treat superficial infections of the eye caused by bacteria. Common infections that can be treated with this solution include conjunctivitis, keratitis and keratoconjunctivitis, blepharitis and blepharoconjunctivitis.

Key Benefits

• Prescribed for bacterial eye infections
• Three effective topical antibiotics in one convenient solution
• For cats and dogs

How It Works

This triple-antibiotic solution is recommended by veterinarians to treat superficial bacterial eye infections by reducing eyelid and eye inflammation and swelling. These infections can include:

• Blepharoconjunctivitis
• Blepharitis
• Keratoconjunctivitis
• Keratitis
• Conjunctivitis

Indications

Neomycin and Polymyxin B Sulfates and Gramicidin Ophthalmic Solution, USP is indicated for the topical treatment of superficial infections of the external eye and its adnexa caused by susceptible bacteria. Such infections encompass conjunctivitis, keratitis and keratoconjunctivitis, blepharitis and blepharoconjunctivitis.

Instill one or two drops into the affected eye every 4 hours for 7 to 10 days. In severe infections, dosage may be increased to as much as two drops every hour.

Contraindications:

This product is contraindicated in those persons who have shown hypersensitivity to any of its components.

Warnings:

Not for Injection into the Eye. This product should never be directly introduced into the anterior chamber of the eye or injectedsubconjunctivally.

Topical antibiotics, particularly neomycin sulfate, may cause cutaneous sensitization. A precise incidence of hypersensitivity reactions (primarily skin rash) due to topical antibiotics is not known.

The manifestations of sensitization to topical antibiotics are usually itching, reddening and edema of the conjunctiva and eyelid. A sensitization reaction may manifest simply as a failure to heal. During long-term use of topical antibiotic products, periodic examination for such signs is advisable, and the patient should be told to discontinue the product if they are observed. Symptoms usually subside quickly on withdrawing the medication. Applications of products containing these ingredients should be avoided for the patient thereafter. (See Precautions: General.)

Precautions:

General

As with other antibiotic preparations, prolonged use of this product may result in overgrowth of nonsusceptible organisms including fungi. If superinfection occurs, appropriate measures should be initiated.

Bacterial resistance to this product may also develop. If purulent discharge, inflammation or pain becomes aggravated, the patient should discontinue use of the medication and consult a physician.

There have been reports of bacterial keratitis associated with the use of topical ophthalmic products in multiple-dose containers which have been inadvertently contaminated by patients, most of whom had a concurrent corneal disease or a disruption of the ocular epithelial surface (see Precautions: Information for Patients).

Allergic cross-reactions may occur which could prevent the use of any or all of the following antibiotics for the treatment of future infections: kanamycin, paromomycin, streptomycin, and possibly gentamicin.

Information for Patients

Patients should be instructed to avoid allowing the tip of the dispensing container to contact the eye, eyelid, fingers, or any other surface. The use of this product by more than one person may spread infection.

Patients should also be instructed that ocular products, if handled improperly, can become contaminated by common bacteria known to cause ocular infections. Serious damage to the eye and subsequent loss of vision may result from using contaminated products (see Precautions: General). If the condition persists or gets worse, or if a rash or other allergic reaction develops, the patient should be advised to stop use and consult a physician. Do not use this product if you are allergic to any of the listed ingredients.

Keep tightly closed when not in use. Keep out of reach of children.

Adverse Reactions:

Adverse reactions have occurred with the anti-infective components of this product. The exact incidence is not known. Reactions occurring most often are allergic reactions including itching, swelling, and conjunctival erythema (see Warnings). More serious hypersensitivity reactions, including anaphylaxis, have been reported rarely.

Local irritation on instillation has also been reported.

To report SUSPECTED ADVERSE REACTIONS, contact Bausch + Lomb, a division of Valeant Pharmaceuticals North America LLC, at 1-800-321-4576 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Storage:

Store between 15°-25° C (59°-77° F).