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Ketoconazole is commonly used to treat systemic fungal infections and can also be used to reduce the doses and costs of cyclosporine treatment by interfering with cyclosporine drug metabolism. Treatment may be required for a longer period of time to get rid of the fungal infection. Ketoconazole may also reduce the synthesis of the male hormone testosterone. As a result, infertility may result from ketoconazole therapy in male dogs.
Ketoconazole is an antifungal medication that blocks the formation of cortisol in the adrenal glands and for that reason is used in the treatment of Cushing's disease.
Ketoconazole tablets are not indicated for treatment of onychomycosis, cutaneous dermatophyteinfections, or Candida infections.
Ketoconazole tablets should be used only when other effective antifungal therapy is not available ortolerated and the potential benefits are considered to outweigh the potential risks.
Ketoconazole tablets are indicated for the treatment of the following systemic fungal infections inpatients who have failed or who are intolerant to other therapies: blastomycosis, coccidioidomycosis,histoplasmosis, chromomycosis, and paracoccidioidomycosis. Ketoconazole tablets should not be usedfor fungal meningitis because it penetrates poorly into the cerebrospinal fluid.
Tip: Results of treatment may not be seen for 1 or 2 weeks and the duration of treatment may last up to several months. The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. Make sure you complete the prescription unless specifically directed by your veterinarian. Even if your pet feels better, the entire treatment plan should be completed to prevent relapse or prevent the development of resistance.
Ketoconazole Dosage for Cats | |
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Weight | Dosage |
All weights | Dosage depends on the particular disease being treated. |
Ketoconazole Dosage for Dogs | |
Weight | Dosage |
All weights | Dosage depends on the particular disease being treated. |
Ketoconazole can interact with many other drugs. Fully disclose to your veterinarian any medications your pet is taking before giving ketoconazole. Do not use in pregnant or nursing animals.
May cause infertility in male dogs by decreasing testosterone synthesis. Testosterone production rebounds once the drug is discontinued.
Keep out of reach of children and animals.
Store at room temperature in well-closed containers.