What is compounding?
Drug compounding is often regarded as the process of combining or mixing drugs to create a medication tailored to the needs of an individual patient.
The generic form of Vetmedin is Pimobendan.
Vetmedin is in limited supply. Orders placed will be shipped as product continues to come off backorder.
Dexamethasone is a solution prescribed to help reduce inflammation found in the eye, including pinkeye. This easy-to-use medication helps to provide relief by reducing burning and redness. Plus, Dexamethasone comes with a convenient eye dropper for accurate dosing.
Dexamethasone Sodium Phosphate Ophthalmic Solution is an anti-inflammatory corticosteroid.
For the treatment of the following conditions:
Ophthalmic: Steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea,and anterior segment of the globe, such as allergic conjunctivitis, acne rosacea, superficial punctatekeratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitis when the inherenthazard of steroid use is accepted to obtain an advisable diminution in edema and inflammation; cornealinjury from chemical or thermal burns, or penetration of foreign bodies.
Otic: Steroid responsive inflammatory conditions of the external auditory meatus, such as allergic otitisexterna, selected purulent and nonpurulent infective otitis externa when the hazard of steroid use isaccepted to obtain an advisable diminution in edema and inflammation.
Apply as directed by your veterinarian every 2-4 hours. When using the drops, shake the drops to make sure the medication is mixed well. If using more than 1 drop, wait about 1 minute between drops.
Epithelial herpes simplex keratitis (dendritic keratitis). Acute infectious stages of vaccinia, varicella,and many other viral diseases of the cornea and conjunctiva.
Mycobacterial infection of the eye.
Fungal diseases of ocular or auricular structures.
Hypersensitivity to any component of this product, including sulfites (see Warnings).
Perforation of a drum membrane.
Prolonged use may result in ocular hypertension and/or glaucoma, with damage to the optic nerve,defects in visual acuity and fields of vision, and posterior subcapsular cataract formation. Prolongeduse may suppress the host response and thus increase the hazard of secondary ocular infections. Inthose diseases causing thinning of the cornea or sclera, perforations have been known to occur with theuse of topical corticosteroids. In acute purulent conditions of the eye or ear, corticosteroids may maskinfection or enhance existing infection. If these products are used for 10 days or longer, intraocularpressure should be routinely monitored even though it may be difficult in children and uncooperativepatients.
Employment of corticosteroid medication in the treatment of herpes simplex other than epithelial herpessimplex keratitis, in which it is contraindicated, requires great caution; periodic slit-lamp microscopy isessential.
This product contains sodium bisulfite, a sulfite that may cause allergic-type reactions includinganaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptiblepeople. The overall prevalence of sulfite sensitivity in the general population is unknown and probablylow. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.
The possibility of persistent fungal infections of the cornea should be considered after prolongedcorticosteroid dosing.
There have been reports of bacterial keratitis associated with the use of multiple dose containers oftopical ophthalmic products. These containers had been inadvertently contaminated by patients who, inmost cases, had a concurrent corneal disease or a disruption of the ocular epithelial surface. (See Precautions, Information for Patients).
Patients should be instructed to avoid allowing the tip of the dispensing container to contact the eye orsurrounding structures.
Patients should also be instructed that ocular solutions, if handled improperly, can become contaminatedby common bacteria known to cause ocular infections. Serious damage to the eye and subsequent loss ofvision may result from using contaminated solutions. (See Precautions, General).
Patients should also be advised that if they develop an intercurrent ocular condition (e.g., trauma, ocularsurgery or infection), they should immediately seek their physician's advice concerning the continueduse of the present multidose container.
One of the preservatives in dexamethasone sodium phosphate ophthalmic solution, benzalkoniumchloride, may be absorbed by soft contact lenses. Patients wearing soft contact lenses should beinstructed to wait at least 15 minutes after instilling dexamethasone sodium phosphate ophthalmicsolution before they insert their lenses.
Long-term animal studies have not been performed to evaluate the carcinogenic potential or the effecton fertility of dexamethasone sodium phosphate ophthalmic solution.
Pregnancy Category C: Dexamethasone has been shown to be teratogenic in mice and rabbitsfollowing topical ophthalmic application in multiples of the therapeutic dose.
In the mouse, corticosteroids produce fetal resorptions and a specific abnormality, cleft palate. In therabbit, corticosteroids have produced fetal resorptions and multiple abnormalities involving the head,ears, limbs, palate, etc.
There are no adequate or well-controlled studies in pregnant women. Dexamethasone sodium phosphateophthalmic solution should be used during pregnancy only if the potential benefit to the mother justifiesthe potential risk to the embryo or fetus. Infants born of mothers who have received substantial doses ofcorticosteroids during pregnancy should be observed carefully for signs of hypoadrenalism.
Glaucoma with optic nerve damage, visual acuity and field defects, posterior subcapsular cataractformation, secondary ocular infection from pathogens including herpes simplex, perforation of theglobe.
Rarely, filtering blebs have been reported when topical steroids have been used following cataractsurgery.
Rarely, stinging or burning may occu
Store between 15°-25°C (59°-77°F).
Do not use in animals hypersensitive (allergic) to any of the ingredients.
Do not use in fungal or viral infections of the eye before healing has started. Also do not use if an ulcer on the eye could be present, since it could cause the ulcer to worsen or rupture. Therefore, an ophthalmic exam by a veterinarian is necessary before using this medication.
Prolonged use may result in a serious bacterial or fungal infection.
Prevent ingestion of the medication. If ingested at high doses or for extended periods, corticosteroids can cause premature birth. In dogs, rabbits, and rodents, corticosteroids can cause birth defects.
se with caution in animals with diabetes mellitus or Cushing's disease (hyperadrenocorticism).
Consult with your veterinarian regarding the eye examinations and laboratory testing necessary prior to and during treatment with corticosteroid ophthalmic preparations.
Side effects are unusual with this medication. Rarely, pressure may increase inside the eye, cataracts may form, or a perforation of the cornea may occur. Other, more common side effects may include burning, stinging, itching, redness, blurred vision, or sensitivity to light.
If ingested, the most common side effect of corticosteroids is an increase in the amount of drinking and urinating. Less commonly may see an increased appetite and weight gain, panting, diarrhea, vomiting, and behavior changes.