Bravecto Topical Solution for Dogs - 22-44 lbs (4 Tubes)

Bravecto (Fluralaner) is a Topical Solution for Dogs that kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks. Bravecto is also indicated for the treatment and control of Amblyomma americanum (lone star tick) infestations for 8 weeks.

Provides dogs up to 12 weeks of flea and tick protection in just 1 dose

Longest-lasting protection available in a topical solution

Kills adult fleas and is indicated for the treatment and prevention of flea infestations and the treatment and control of tick infestations for 12 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater.

Fast-acting, long-lasting protection

Easy topical application with an easy to use, non-spill twist applicator

Lasts nearly 3X longer than monthly treatments

Resists repeated swimming/bathing for a full 12-week* period

Safe for breeding, pregnant or nursing dogs

For dogs who prefer a chew, talk to your veterinarian about Bravecto® (fluralaner) Chews for Dogs

Active ingredient(s): Fluralaner

Bravecto should be administered topically as a single dose every 12 weeks according to the Dosage Schedule below to provide a minimum dose of 11.4 mg/lb (25 mg/kg) body weight. Bravecto may be administered every 8 weeks in case of potential exposure to Amblyomma americanum ticks (see Effectiveness).

Contraindications: There are no known contraindications for the use of the product.

Dosage Schedule

Body Weight Ranges (lb)	Fluralaner Content (mg)/tube	Tubes Administered
4.4-9.9	112.5	One
>9.9-22.0	250	One
>22.0-44.0	500	One
>44.0-88.0	1000	One
>88.0-123.0*	1400	One

*dogs over 123.0 lbs should be administered the appropriate combination of tubes.

Storage Information: Do not store above 77°F (25°C). Store in the original package in order to protect from moisture. The pouch should only be opened immediately prior to use.

Who is Bravecto Topical Solution for Dogs for? For Dogs and Puppies 6 months of age and older weighing 4.4 pounds or greater

How does Bravecto Topical Solution for Dogs work? Fluralaner is for systemic use and belongs to the class of isoxazoline-substituted benzamide derivatives. Fluralaner is an inhibitor of the arthropod nervous system. The mode of action of fluralaner is the antagonism of the ligand-gated chloride channels (gamma-aminobutyric acid (GABA)-receptor and glutamate-receptor).

Why use Bravecto Topical Solution for Dogs?

Provides flea and tick treatment for up to 12 weeks (8 weeks for the lone star tick) in just 1 dose

Treatment may begin at any time of the year and can continue year round without interruption

Bathing or water immersion 3 days after administration will not reduce the effectiveness of Bravecto against fleas and Ixodes ricinus ticks

Longest-lasting protection available in a topical solution

Available by veterinary prescription only

Effectiveness: In well-controlled laboratory studies, Bravecto killed fleas and reduced the numbers of live fleas on dogs by >99% and 100% within 24 and 48 hours, respectively, post-infestation for 12 weeks. In well-controlled laboratory studies, Bravecto demonstrated ?93.3% effectiveness against Dermacentor variabilis, Ixodes scapularis and Rhipicephalus sanguineus 48 hours post-infestation for 12 weeks. Bravecto demonstrated ?90% effectiveness against Amblyomma americanum 72 hours post-infestation for 8 weeks, but failed to demonstrate ?90% effectiveness beyond 8 weeks.

In a well-controlled U.S. field study, a single dose of Bravecto reduced fleas by ?99.8% for 12 weeks. Dogs with signs of flea allergy dermatitis showed improvement in erythema, alopecia, papules, scales, crusts, and excoriation as a direct result of eliminating flea infestations.

In a European laboratory study, Bravecto demonstrated ?98.2% effectiveness against fleas and Ixodes ricinus ticks after multiple water immersion or shampooing occasions, the first occurring 3 days after application, for 12 weeks.