Elanco Zenrelia (Ilunocitinib) Tablets for Dogs - 8.5mg (1 Count) - [Allergic Itch & Inflammation Relief]

Allergic dermatitis can make your dog very uncomfortable. Symptoms like excessive itching, scratching, and biting aren't only disruptive to you and your pet, but they can also cause more severe problems over time, including hair loss and skin infection.

Zenrelia (ilunocitinib tablets) is a once-daily tablet that relieves itching due to allergic dermatitis and controls atopic dermatitis.

Zenrelia is designed to begin working rapidly.* The active ingredient, ilunocitinib, reduces the inflammatory response in your dog's skin caused by allergies, making your dog feel less itchy. What's more, Zenrelia is designed to deliver continuous efficacy over the long term and can get your dog back to normal**.

Dogs should not take Zenrelia for at least 28 days to 3 months prior to vaccination and should not take Zenrelia for at least 28 days after vaccination. Discuss your dog’s vaccine schedule with your veterinarian. Zenrelia is given once a day with or without food, so it may be easier to incorporate into your daily routine. Always follow your veterinarian's instructions. The most common side effects reported with this dog dermatitis treatment were vomiting, diarrhea and tiredness; see package insert including the Boxed Warning.

Zenrelia is a prescription itch relief medication for dogs at least 12 months of age. Ask your veterinarian if Zenrelia can relieve itching in your dog due to allergic and atopic dermatitis. Fast relief for your best friend is also a relief for you. Spend more time doing the things you love, like cuddling and playing, and less time managing your dog's allergy symptoms.

* Forster S, Boegel A, Despa S, et al. Comparative efficacy and safety of ilunocitinib and oclacitinib for the control of pruritus and associated skin lesions in dogs with atopic dermatitis. Veterinary Dermatology. 2025; 1–10
** Clinical remission of itch demonstrated by a Normal-PVAS<2

Key Features

• Zenrelia relieves itching in dogs due to allergic dermatitis and controls atopic dermatitis
• Zenrelia works fast, providing visible improvements in itch* * Forster S, Boegel A, Despa S, et al. Comparative efficacy and safety of ilunocitinib and oclacitinib for the control of pruritus and associated skin lesions in dogs with atopic dermatitis. Veterinary Dermatology. 2025; 1–10
• Ilunocitinib, the active ingredient in Zenrelia, works by reducing the itch and inflammatory response in your dog's skin due to allergies
• The most common side effects reported with this dog dermatitis treatment were vomiting, diarrhea and tiredness; see package insert including the Boxed Warning
• The once-daily tablet can be given with or without food from the comfort of your home

Active Ingredients
ilunocitinib

Directions for Use
Once daily, oral tablet for the control of itch associated with allergic and atopic dermatitis, in dogs 12 months and up.

Storage Instructions
Once daily, oral tablet for the control of itch associated with allergic and atopic dermatitis, in dogs 12 months and up.

Safety Warning
IMPORTANT SAFETY INFORMATION See package insert including the Boxed Warning. For full prescribing information speak with your veterinarian, call 1 888 545 5973 or visit www.elancolabels.com/us/zenrelia.

WARNING: VACCINE-INDUCED DISEASE AND INADEQUATE IMMUNE RESPONSE TO VACCINES. Based on results of the vaccine response study, dogs receiving Zenrelia are at risk of fatal vaccine-induced disease from modified live virus vaccines and inadequate immune response to any vaccine. Discontinue Zenrelia for at least 28 days to 3 months prior to vaccination and withhold Zenrelia for at least 28 days after vaccination.

Dogs should be up to date on vaccinations prior to starting Zenrelia. Do not use in dogs less than 12 months old or dogs with a serious infection. Dogs should be monitored for the development of infections because Zenrelia may increase the chances of developing an infection. Neoplastic conditions (benign and malignant) were observed during clinical studies. The most common side effects were vomiting, diarrhea and tiredness. Zenrelia has not been tested in dogs used for breeding, pregnant, or lactating dogs and has not been evaluated in combination with glucocorticoids, cyclosporine, or other immune suppressive drugs.