VETIGEL Hemostatic Gel, 5ml syringe, (2 pack) | On Sale | EntirelyPets Rx
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VETIGEL Hemostatic Gel, 5ml syringe, (2 pack)

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Description

VETIGEL Hemostatic Gel is an advanced medical product designed to stop bleeding quickly and effectively. It is a hemostatic agent used by veterinarians and healthcare professionals to control bleeding in animals and humans. VETIGEL is known for its rapid action and ease of use in various medical situations.

Key Benefits:

  • Rapid Hemostasis: VETIGEL is engineered to swiftly stop bleeding by forming a gel-like barrier over the wound site, sealing it and preventing further blood loss.
  • Versatile Application: It can be used in a wide range of situations, including surgical procedures, traumatic injuries, and even in dental surgeries for pets.
  • Ease of Use: VETIGEL is designed for easy application. It can be applied directly to the bleeding site, adhering quickly to provide immediate hemostatic control.
  • Biocompatible: The gel is biocompatible, meaning it is safe for use in both animals and humans. It does not cause tissue irritation or adverse reactions.
  • Reduced Risk of Infection: By sealing the wound rapidly, VETIGEL helps reduce the risk of infection, promoting a faster and smoother recovery process.
  • Quick Application: VETIGEL's efficient application reduces the time and effort required to control bleeding, which can be crucial in emergency situations.

How it Works:

VETIGEL Hemostatic Gel is a cutting-edge medical product designed to rapidly control bleeding in both veterinary and human medicine. Its mechanism of action involves a combination of advanced biotechnology and natural coagulation processes to achieve hemostasis (the cessation of bleeding). Here's how it works:

  1. Application to the Wound:
    • When applied to a bleeding wound, VETIGEL Hemostatic Gel is carefully administered directly onto the site of hemorrhage. It adheres quickly to the wound's surface, creating an immediate physical barrier.
  2. Formation of the Gel Matrix:
    • VETIGEL's proprietary formulation contains special molecules that react with blood components, especially the proteins and platelets present in the bloodstream. These interactions trigger the rapid formation of a gel-like matrix at the bleeding site. This matrix effectively seals the wound, preventing further blood loss.
  3. Enhanced Clotting Mechanism:
    • VETIGEL actively supports the body's natural clotting mechanisms. It accelerates the aggregation of platelets, which are responsible for initiating clot formation. The gel matrix provides an optimal environment for platelet activation, allowing them to bind together and form a stable clot.
  4. Hemostasis Achievement:
    • As the gel matrix takes shape and the clot stabilizes, bleeding is swiftly controlled. This results in the cessation of blood loss, even in cases of moderate to severe hemorrhage.
  5. Biocompatible and Absorbable:
    • VETIGEL is designed to be biocompatible, meaning it is safe for use within the body. It does not induce adverse reactions or tissue irritation. Over time, as the wound heals, VETIGEL is naturally absorbed by the body without the need for removal or additional intervention.
  6. Reduced Risk of Infection:
    • The quick formation of the gel matrix not only stops bleeding but also creates a barrier that reduces the risk of infection by preventing external contaminants from entering the wound.
  7. Ease of Use:
    • One of the key advantages of VETIGEL is its ease of use. Healthcare professionals and veterinarians can quickly and efficiently apply it in emergency situations or during surgical procedures.

VETIGEL Hemostatic Gel utilizes a unique combination of biochemical and physical processes to achieve rapid hemostasis. It forms a gel matrix at the bleeding site, promotes platelet activation, and accelerates clot formation, ultimately stopping bleeding and supporting the body's natural healing process. This innovative product has become an invaluable tool in medical and veterinary settings for managing bleeding effectively and improving patient outcomes.

Directions

Administration of VETIGEL Hemostatic Gel:

  1. Preparation: Before administering VETIGEL Hemostatic Gel, ensure that you have the necessary materials and have assessed the wound or bleeding site. It's essential to follow proper hygiene and safety protocols.
  2. Gel Application:
    • Clean the Wound: Gently clean the wound or bleeding site with sterile saline solution or water, if possible. Remove any debris or foreign objects to ensure a clean application surface.
    • Control Bleeding: Attempt to control any active bleeding by applying direct pressure with a sterile gauze or bandage. This step is crucial for effective hemostasis.
    • Apply VETIGEL: Once the bleeding is under control, carefully apply VETIGEL Hemostatic Gel directly onto the wound. Use enough gel to cover the entire affected area. It adheres quickly and begins the hemostatic process.
  3. Spread and Mold: To ensure proper coverage and adherence, gently spread and mold the gel over the wound using a clean, sterile instrument or gloved hands. Ensure that the entire bleeding site is adequately covered.
  4. Monitoring: After applying VETIGEL, monitor the wound closely. Observe for any signs of renewed bleeding or unusual reactions. If bleeding persists or if you notice any adverse effects, seek immediate medical or veterinary attention.
  5. Additional Dressing: Depending on the nature and location of the wound, your healthcare professional or veterinarian may recommend applying an additional sterile dressing or bandage over the VETIGEL to provide further protection and support.
  6. Follow Professional Guidance: It's crucial to administer VETIGEL Hemostatic Gel under the guidance of a trained healthcare professional or veterinarian. They can provide specific instructions tailored to the patient's condition and ensure proper application techniques.
  7. Single-Use Product: VETIGEL is typically a single-use product. Dispose of any unused portions according to local regulations and safety guidelines.
  8. Patient Care: Following the application of VETIGEL, continue to provide appropriate care to the patient. This may include wound care, monitoring for signs of infection, and any necessary follow-up appointments.
  9. Storage: Store VETIGEL Hemostatic Gel as per the manufacturer's recommendations, typically in a cool, dry place, away from direct sunlight.

Remember that the proper administration of VETIGEL is crucial for its effectiveness in controlling bleeding. Always consult with a healthcare professional or veterinarian for guidance on its application, especially in emergency situations or during surgical procedures. Timely and correct administration can make a significant difference in patient outcomes and recovery.

Important Safety Information:

  1. Professional Use: VETIGEL Hemostatic Gel is primarily intended for use by trained veterinarians and healthcare professionals. Proper training and understanding of its application are essential for safe and effective use.
  2. Compatibility: VETIGEL is compatible with most commonly used surgical and wound management products. However, always consult the product's instructions for specific compatibility information.
  3. Single Use: VETIGEL is typically a single-use product. Dispose of any unused portions properly and in accordance with local regulations.
  4. Allergic Reactions: While VETIGEL is generally well-tolerated, individuals or animals with known allergies to its components should avoid its use. If an allergic reaction occurs, discontinue use and seek medical or veterinary assistance.
  5. Side Effects: In rare cases, mild side effects such as redness or irritation at the application site may occur. If you observe any unusual reactions, consult a healthcare professional or veterinarian.
  6. Consult a Professional: In emergency situations, it is crucial to consult a healthcare professional or veterinarian for guidance on using VETIGEL to ensure the best possible outcomes.

Remember that VETIGEL Hemostatic Gel is a valuable tool in managing bleeding effectively. Always use it in accordance with professional guidance and best practices to achieve optimal results and ensure the safety and well-being of the patient.

FAQ

VETIGEL is a flowable hemostatic gel comprised of algae- and fungi-derived biopolymers. Its components are sodium alginate, poly (N-acetyl-D-glucosamine, D-glucosamine) and water.
VETIGEL acts as a hemostatic wound covering and plug to stop bleeding. Once gel is applied to a wound, it maintains local pressure and adhesion to aid in the quickening of clot formation via tamponade action. Gel that comes directly in contact with blood crosslinks and forms a strong barrier that maintains durable and long-term hemostasis at the wound site.

VETIGEL is applied by following four steps:

  1. Prime the syringe
  2. Use gauze to remove excess blood from the field
  3. Perpendicularly administer gel, directly to the wound
  4. Shear the gel against the tissue while pulling the syringe away from the wound

VETIGEL is a plant-based biopolymer solution made of sodium alginate, poly (N-acetyl-D- glucosamine, D-glucosamine) and water. Given VETIGEL is a hydrogel mainly comprised of water, the significant majority (>80%) of the product is absorbed within weeks. The residual poly (N-acetyl-D-glucosamine, D-glucosamine) is expected to degrade in the body enzymatically, and alginates traditionally degrade via acid hydrolysis and/or dissolving due to ion exchange.

VETIGEL has been subjected to human-grade ISO 10993 biocompatibility testing, including long-term implantation studies that have shown the material does not present long-term risk to the patient.

Yes. VETIGEL is terminally sterilized via gamma irradiation.
VETIGEL Dental Accessories are not claimed to be sterile. VETIGEL® Dental Accessories are cleaned and disinfected via steam autoclave.
VETIGEL was assessed for its biocompatibility per ISO 10993 (human medical device biocompatibility standards) that was interpreted for veterinary use. This testing included cytotoxicity, intracutaneous reactivity, maximization sensitization, pyrogenicity, genotoxicity, and more. The results of the testing confirmed that VETIGEL is biocompatible and give assurance that VETIGEL® does not pose risk of rejection by the body.
VETIGEL is comprised of sodium alginate dissolved in water with solid particles of poly (N- acetyl-D-glucosamine, D-glucosamine) dispersed in it. In two limited studies, use of VETIGEL was not shown to result in a clinically significant increase in adhesion formation as compared to existing standards of care. While granular materials may be known to increase risk of adhesions, alginates are known to have well-established anti-adhesion properties.
VETIGEL's primary mechanism of action is mechanical (i.e. tamponade) and occurs independently of the patient's clotting process. VETIGEL has not been evaluated in coagulopathic patients. Removal of VETIGEL from a treatment site in patients with coagulopathy may result in rebleeding due to the lack of a durable clot.
Yes, VETIGEL can be applied topically.
The use of VETIGEL is being investigated in procedures outside of dental/oral surgery, enucleations, biopsies, and other surgical use cases. VETIGEL has not been evaluated in neurological procedures, and though there is no indication that it poses significant short-term risk post-application, the long-term risks are currently unknown. Long-term exposure of neurological tissue to granular particles may cause risk.
The use of VETIGEL is being investigated in procedures outside of dental/oral surgery, enucleations, biopsies, and other surgical use cases. VETIGEL has not been evaluated in epistaxis procedures, though there is no indication that it poses short-term risk post-application.
VETIGEL's gel form lends itself to easily flowability and conformance to complex wound geometries. Due to its ionic crosslinking nature in the presence of blood, VETIGEL has been observed forming a plasticized, strong matrix at the bleeding sites, which may reduce or eliminate the risk of fragmentation. This functionality was designed into the product to improve upon many existing standards of care (sponges, powders) that may present this risk. The risk of an embolic event after administering VETIGEL has not been formally evaluated in a clinical setting.

Sodium alginate is a widely used biopolymer in wound dressings intended to keep wounds moist and to promote wound healing. Poly (N-acetyl-D-glucosamine, D-glucosamine) is often used as an antimicrobial agent in medical devices. These materials have been used in ISO 10993 biocompatibility studies and in clinical scenarios where there have been no reports of increased infection.

The risk of increased infection after administering VETIGEL has not been formally evaluated in a clinical setting. Use standard of care practices when applying VETIGEL in contaminated areas.

VETIGEL has no known or expected interactions with drugs.
Yes, VETIGEL's constituent polymers are safe for ingestion. However, this is not recommended.

Contraindications:

  • The safety and effectiveness of VETIGEL for use in ophthalmic procedures have not been established.
  • VETIGEL is not intended to be used for controlling menorrhagia.
  • VETIGEL is not intended to be used as a wound-closure device.

Warnings:

  • Do not use VETIGEL in Equus due to pyrogen sensitivity.
  • Do not inject VETIGEL intravascularly due to risk of embolization.
  • Do not close the mucosa over VETIGEL (in dental)
Store VETIGEL in a refrigerator (2-8°C) upon receipt. VETIGEL has a shelf life of 15 months upon storage. See Instructions For Use for further information.

VETIGEL can be used on a variety of procedures, including but not limited to:

Dental extractions, oral mass removals, abdominal and thoracic mass removals, soft organ biopsies, enucleations, spays & neuters, amputations, venous & arterial bleeds, cholecystectomies, catheterization, lacerations, and ear & tail docking.

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