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Tri-Otic Ointment Tube 7.5gm

Item# HA20111940
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Description

Tri-Otic Ointment is a prescription medication used to treat acute and chronic external ear infections, caused by bacteria and yeast. It also reduces inflammation, pain and itching, while it reduces ear wax production. This safe, effective formula comes as an ointment to be placed easily in the ears.

Key Benefits

  • Treats ear infections due to bacteria and yeast
  • Reduces inflammation, pain, and itching
  • Also helps reduce ear wax production

Powerful Tri-otic ointment is effective because it blends three antimicrobials into one medication for treating ear infections. This combination of gentamicin sulfate, betamethasone valerate and clotrimazole work together to stop bacteria and yeast, which are the source of infections, while soothing the symptoms including pain, swelling, and annoying itching.

Indications

Gentamicin-betamethasone-clotrimazole ointment is indicated for the treatment ofcanine acute and chronic otitis externa associated with yeast (Malassezia pachydermatis, formerlyPityrosporum canis) and/or bacteria susceptible to gentamicin.

Ingredients

Active Ingredients:

Gentamicin Sulfate, USP equivalent to 3 mg Gentamicin base; Betamethasone Valerate, USP equivalent to 1 mg Betamethasone; and 10 mg Clotrimazole, USP.

Inactive Ingredients:

Mineral oil-based system containing a plasticized Hydrocarbon gel.

Directions

View Tri-Otic Drug Facts Sheet.

The external ear should be thoroughly cleaned and dried before treatment. Remove foreign material, debris, crusted exudates, etc., with suitable non-irritating solutions. Excessive hair should be clipped from the treatment area. After verifying that the eardrum isintact, instill 4 drops (2 drops from the 215 g. bottle) of gentamicin-betamethasone-clotrimazole ointment twice daily into the ear canal of dogs weighing less than 30 lbs. Instill 8 drops (4 drops fromthe 215 g. bottle) twice daily into the ear canal of dogs weighing 30 lbs. or more. Therapy should continue for 7 consecutive days.

Cautions:

Federal law restricts this drug to use by or on the order of a licensed veterinarian. Keep this and all drugs out of the reach of children.

Contraindications:

If hypersensitivity to any of the components occurs, treatment should be discontinued and appropriate therapy instituted. Concomitant use of drugs known to induce ototoxicity should be avoided. Do not use in dogs with known perforation of eardrums.

Warnings:

The use of gentamicin-betamethasone-clotrimazole ointment has been associated with deafness or partial hearing loss in a small number of sensitive dogs (e.g. geriatric). The hearing deficitis usually temporary. If hearing or vestibular dysfunction is noted during the course of treatment, discontinue use of gentamicin-betamethasone-clotrimazole ointment immediately and flush the ear canal thoroughly with a non-ototoxic solution. Corticosteroids administered to dogs, rabbits, and rodents during pregnancy have resulted in cleft palate in offspring. Other congenital anomalies including deformed forelegs, phocomelia, and anasarca have been reported in offspring of dogs which received corticosteroids during pregnancy.

Clinical and experimental data have demonstrated that corticosteroids administered orally orparenterally to animals may induce the first stage of parturition if used during the last trimester ofpregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta,and metritis.

Precautions:

Identification of infecting organisms should be made either by microscopic rollsmear evaluation or by culture as appropriate. Antibiotic susceptibility of the pathogenic organism(s)should be determined prior to use of this preparation.

If overgrowth of non-susceptible bacteria, fungi, or yeasts occur, or if hyper-sensitivity develops,treatment should be discontinued and appropriate therapy instituted.

Administration of recommended doses of gentamicin-betamethasone-clotrimazole ointment beyond 7 days may result in delayed wound-healing.

Avoid ingestion. Adverse systemic reactions have been observed following the oral ingestion of sometopical corticosteroid preparations. Patients should be closely observed for the usual signs of adrenocorticoid overdosage which include sodium retention, potassium loss, fluid retention, weightgain, polydipsia, and/or polyuria. Prolonged use or overdosage may produce adverse immuno suppressive effects.

Use of corticosteroids, depending on dose, duration, and specific steroid, may result in endogenous steroid production inhibition following drug withdrawal. In patients presently receiving or recently withdrawn from corticosteroid treatments, therapy with a rapidly acting corticosteroid should be considered in especially stressful situations.

Before instilling any medication into the ear, examine the external ear canal thoroughly to be certain the tympanic membrane is not ruptured in order to avoid the possibility of transmitting infection to the middle ear as well as damaging the cochlea or vestibular apparatus from prolonged contact.

Storage:

2° and 25°C (36° and 77°F).

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