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Temaril-P 5mg (per tablet)

Item# HA2011386S
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Recurring Saings in EprxAUTOSHIP & SAVE[Details]
Recurring Saings in EprxAUTOSHIP & SAVE[Details]
$1.17Reg $1.40
$117.00Reg $152.99
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Temaril-P is used to treat itching and coughing (including kennel cough) in dogs. Temaril-P is a combination antihistamine (trimeprazine) and corticosteroid (prednisolone). Temaril-P is used for the relief of itching regardless of cause. It is also used in the treatment of various cough conditions such as kennel cough, bronchitis and coughs of nonspecific origin. Temaril-P may also be used for purposes other than those listed here.

Key Benefits

  • Canine antipruritic, antitussive tablet.
  • Combines antipruritic, antitussive activity of trimeprazine with anti-inflammatory effect of prednisolone.
  • For relief of itching regardless of cause.
  • Recommended for treatment of "kennel cough" (tracheobronchitis).

How It Works

Temaril-P contains trimeprazine and prednisolone. Trimeprazine is an antihistamine, which helps relieve itching and coughing. Prednisolone is a corticosteroid that reduces inflammation.

Indications & Usage

  1. Antipruritic - Temaril-P is recommended for the relief of itching regardless of cause. Its usefulness has been demonstrated for the relief of itching and the reduction of inflammation commonly associated with most skin disorders of dogs such as the eczema caused by internal disorders, otitis, and dermatitis (allergic, parasitic, pustular, and nonspecific). It often relieves pruritus which does not respond to other therapy. With any pruritus treatment, the cause should be determined and corrected; otherwise, signs are likely to recur following discontinuance of therapy.
  2. Antitussive - Temaril-P has been found to be effective therapy and adjunctive therapy in various cough conditions of dogs. Therefore, in addition to its antipruritic action, Temaril-P is recommended for the treatment of "kennel cough" or tracheobronchitis, bronchitis including all allergic bronchitis, and infections and coughs of nonspecific origin. (Coughs due to cardiac insufficiencies would not be expected to respond to Temaril-P therapy.) As with any antitussive treatment, the etiology of the cough should be determined and eliminated if possible. Otherwise, symptoms are likely to recur following discontinuance of therapy.

Note: Temaril-P may be administered to animals suffering from acute or chronic bacterial infections provided the infection is controlled by appropriate antibiotic or chemotherapeutic agents.


View Temaril-P Drug Facts Sheet.

The same dosage schedule may be followed for both antipruritic and anti-tussive therapy.

Weight Initial Dosage
Up to 10 lb 1/2 tablet, twice daily
11-20 lb 1 tablet, twice daily
21-40 lb 2 tablets, twice daily
Over 40 lb 3 tablets, twice daily

After 4 days, reduce dosage to 1/2 of the initial dose or to an amount just sufficient to maintain remission of symptoms. Individual animal response will vary and dosage should be adjusted until proper response is obtained.


Federal law restricts this drug to use by or on the order of a licensed veterinarian.


Clinical and experimental data have demon-strated that corticosteroids administered orally or by injection to animals may induce the first stage of parturi-tion if used during the last trimester of pregnancy and may precipitate premature parturition followed by dysto-cia, fetal death, retained placenta, and metritis. Addi-tionally, corticosteroids administered to dogs, rabbits, and rodents during pregnancy have resulted in cleft pal-ate in offspring. Corticosteroids administered to dogs during pregnancy have also resulted in other congenital anomalies, including deformed forelegs, phocomelia, and anasarca. If a vasoconstrictor is needed, norepine-phrine should be used in lieu of epinephrine. Pheno-thiazine derivatives may reverse the usual elevating action of epinephrine causing a further lowering of blood pressure.

Precautions & Side Effects

All the precautions applicable to cortisone and to phenothiazine derivatives apply also to Temaril-P. Possible side effects attributableto corticosteroids include sodium retention and potas-sium loss, negative nitrogen balance, suppressed adrenalcortical function, delayed wound healing, osteoporosis, elevated levels of SGPT and SAP, and vomiting and diar-rhea (occasionally bloody). Cushings syndrome in dogs has been reported in association with prolonged or repeated steroid therapy. Possible increased suscepti-bility to bacterial invasion and/or the exacerbation of preexisting bacterial infection may occur in patients receiving corticosteroids. As noted above, however, this problem can be avoided by concomitant use of appropri-ate anti-infective agents. Possible side effects attribu-table to phenothiazine derivatives include sedation; pro-truding nictitating membrane; blood dyscrasias; intensifi-cation and prolongation of the action of analgesics, sedatives and general anesthetics; and potentiation of organophosphate toxicity and the activity of procaine hydrochloride.

It should be remembered that the premonitory signs of cortisone overdosage, such as sodium retention and edema, may not occur with prednisolone. Therefore, the veterinarians must be alert to detect less obvious side effects, such as blood dyscrasias, polydipsia, and polyuria.

The appearance and severity of side effects are dose related and are minimal at the recommended dosage level. If troublesome side effects are encountered, the dosage of Temaril-P should be reduced and discontin-ued unless the severity of the condition being treated makes its relief paramount.

Prolonged treatment with Temaril-P must be withdrawn gradually. Use of corticosteroids, depending on dose, duration, and specific steroid, may result in inhibition of endogenous steroid production following drug with-drawal. In patients presently receiving or recently with-drawn from systemic steroid treatments, therapy with a rapidly acting corticosteroid should be considered in unusually stressful situations.


Store in a Dry, Cool Place at Temperatures Not Above 25°C (77°F)


Temaril-P is a prescription medication that is FDA approved for use in dogs. Temaril-P is available as a scored tablet containing trimeprazine tartrate equivalent to 5 mg trimeprazine and prednisolone 2 mg. Prolonged use of Temaril-P should not be stopped suddenly. There should be a gradual reduction in dosage before stopping. Temaril-P should be taken with food to lessen stomach upset.
Do not give Temaril-P to your pet if the pet has a serious viral or fungal infection. Temaril-P can be given in the presence of acute or chronic bacterial infections provided the infection is controlled by antibiotic. Temaril-P may weaken the pet's immune response and its ability to fight infections. Tell your veterinarian if your pet has diabetes mellitus or any other medical conditions. Tell your veterinarian if your pet is being given en phenytoin, Phenobarbital, diuretics, or insulin. Also tell your veterinarian if the pet is pregnant or lactating.
Give this medication exactly as directed by your veterinarian. Do not give more or less than is prescribed by the veterinarian. If you do not understand the directions ask the pharmacist or veterinarian to explain them to you. The usual dose of Temaril-P is based on weight. For dogs up to 10 lbs give 1/2 tablet, for 11-20 lbs give 1 tablet, 21-40 lbs give 2 tablets, and for dogs 41 lbs and up give 3 tablets. These tablets are given twice a day. After 4 days, the dose is typically reduced to 1/2 the initial dose. Keep plenty of water available for the pet. Temaril-P should be given with food.
If any of the following serious side effects occur, stop giving Temaril-P and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face; hives). Trimeprazine can cause drowsiness, tremors and muscle weakness. Prednisolone may cause symptoms of Cushing's disease which include increased thirst, urination and hunger as well as vomiting and diarrhea. Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet.
Give the missed dose as soon as you remember. However, if is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not give a double dose of the medication.
Seek emergency veterinary medical treatment. Symptoms of overdose may include excess drowsiness, low blood pressure, and seizures.
Do not give Temaril-P to dogs allergic to it or to either of its ingredients. Temaril-P should not be given to dogs that are pregnant or that are diabetic. Temaril-P may cause drowsiness. Do not use any vaccines without checking with the veterinarian.
Do not give any other over the counter or prescription medications, including herbal products, during treatment with Temaril-P without first talking to the veterinarian. Many other medications can interact with Temaril-P resulting in side effects or altered effectiveness. These include sedatives, anesthetics, pain medications, epinephrine and procaine.


Review Summary
3 Reviews
67% (2)
33% (1)
0% (0)
0% (0)
0% (0)
100% Recommend this product (3 of 3 responses)
By Cindy
Temaril P
May 21, 2021
Got my prescription very quickly. Around 1/2 of our vets price. Very impressed.
  • Meds Came quickly.
  • Price is still a bit to high for someone on a fixed income.
By Cindy
Phoenix, AZ
prescription medication
September 5, 2018
My vet recommended this medication for my yorkie who has canine valley fever. It controls severe coughing for long periods of time without side effects I also use it for my other elderly yorkie dealing with congestive heart failure ... simply put, I'd be lost without this medication as it improved the quality of life for both my precious dogs ...
  • every few months blood work necessary to check liver enzymes .... well worth it ... I give both dogs milk thistle for liver support and they're doing fine
By Yvonne S.
Lake Forest Park, WA
Temaril-P 5mg
April 12, 2018
I have use Entirely Pets Pharmacy for a very long time and will continue as they have been very good with filling the prescriptions I order and I receive deliveries promptly.

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