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Methocarbamol Inj USP is a potent skeletal muscle relaxant which has an unusually selective action on the central nervous system, specifically on the internuncial neurons of the spinal cord. This specific action results in a diminution of skeletal muscle hyperactivity without concomitant alteration in normal muscle tone. It is long-acting and essentially non-toxic, and has proved effective in a wide range of disorders involving acute muscle spasm.
The injectable form of methocarbamol is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties.
Adult horses administer 2 to 10mg per lb for moderate conditions and 10 to 25mg per lb for severe conditions. Methocarbamol is for I.V. use and may be given undiluted directly into the vein. The dosage and the frequency of injection should be based on the severity of symptoms and on the therapeutic response seen.