is synthetic progesterone hormone that is given orally to prevent estrus in mares or to control the time that estrus starts. It contains the active ingredient altrenogest. For:
Equine Mares Benefits: Regu-Mate effectively suppresses estrus in 95% of mares after 3 days of treatment. Regu-Mate can help mares attain regular estrus cycles, shorten prolonged estrus, and allow for scheduled breeding of mares during the usual breeding season. It's easy to administer - orally or top-dressed on grain. How it works:
Regu-Mate is synthetic progesterone. When progesterone levels are high, generally estrus will not occur.
Dosage & Administration:
The medication is to be given orally directly into the mouth using a syringe, or in the mare's feed.
Women who are or may be pregnant
Persons with known or suspected breast cancer or a history of breast cancer
Persons with known or suspected estrogen-dependent cancer (some uterine cancers)
Persons with cerebrovascular disease (stroke) or coronary artery disease (hardening of the arteries)
Persons with thrombophlebitis or thromboembolic disorders (blood clots) or a history of these diseases
Women with undiagnosed vaginal bleeding
Persons with tumors that developed while they were using oral ontraceptives or other estrogen containing products
Persons with liver disease
Always follow the dosage instructions provided by your veterinarian. If you have difficulty giving the medication, contact your veterinarian. Be sure to follow all the human precautions.
This medication should only be given to the horse for whom it was prescribed.
Possible side effects of Regu-Mate:
Rarely see side effects at labeled dosages. Slight changes in blood levels of calcium, potassium, or liver enzymes may be seen. Consult your veterinarian if you notice any possible side effects.
If your horse experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.
If you miss giving a dose:
Contact your veterinarian.
If you overdose the pet:
May see muscular tremors and an increased breathing rate. If you know or suspect your pet has had an overdose, or if you observe any of these signs in your pet, contact your veterinarian immediately.
What should I avoid while giving Regu-Mate to my pet:
Notify your veterinarian of any other medications, including vitamins and supplements, your horse is taking while receiving Regu-Mate.
Consult your veterinarian before using Regu-Mate with rifampin, since interactions may occur.
Who should not take it?
Not for use in horses hypersensitive (allergic) to altrenogest. Do not use in mares with a previous or current uterine infection or endometritis, or in male horses.
Consult with your veterinarian regarding the physical examinations and laboratory testing necessary prior to and during treatment with Regu-Mate.
Dispose of any unused product, empty containers or partially consumed feed according to local and national requirements.
Human Precautions: Skin contact must be avoided. Use impervious protective gloves when handling Regu-Mate. The following people should not handle Regu-Mate:
Women of childbearing age should handle this product with extreme caution.
Human Exposure: Regu-Mate can be absorbed through the skin. Wear nonporous gloves and personal protective clothing when handling, measuring and administering Regu-Mate. The absorption of Regu-Mate can be increased if the medication is trapped between occlusive materials (e.g., latex gloves) and the skin.
Avoid contamination of other objects (e.g., pens, countertops, etc.) with Regu-Mate. If contaminated, wash well with soap and water.
If skin is exposed, wash with soap and water. Regu-Mate is oily and requires considerable washing and rinsing to remove the drug. Wash hands after use.
If eyes are exposed, flush with water for 15 minutes and get medical attention. If swallowed, do not induce vomiting, but contact a physician or poison control center.