Proparacaine Hydrochloride Ophthalmic Solution 0.5% (15ml) | On Sale | EntirelyPets Rx
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Proparacaine Hydrochloride Ophthalmic Solution 0.5% (15ml) (Manufacturer may vary)

Item# HA21240292
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Recurring Saings in EprxAUTOSHIP & SAVE[Details]
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Description

Proparacaine Hydrochloride Ophthalmic Solution is indicated for topical anesthesia in ophthalmic practice. Representative ophthalmic procedures in which the preparation provides good local anesthesia include measurement of intraocular pressure (tonometry), removal of foreign bodies and sutures from the cornea, conjunctival scraping in diagnosis and gonioscopic examination; it is also indicated for use as a topical anesthetic prior to surgical operations such as cataract extraction.

Directions

Dosage & Administration

Deep anesthesia as in cataract extraction:

Instill 1 drop to the eye every 5 to 10 minutes for 5 to 7 doses.

Removal of sutures:

Instill 1 or 2 drops to the eye 2 or 3 minutes before removal of stitches.

Removal of foreign bodies:

Instill 1 or 2 drops to the eye prior to operating.

Tonometry:

Instill 1 or 2 drops to the eye immediately before measurement.

Contraindications:

This preparation is contraindicated in patients with known hypersensitivity to any component of the solution.

Warnings:

Not for Injection. For Topical Ophthalmic use only.

Prolonged use of a topical ocular anesthetic may produce permanent corneal opacification with accompanying loss of vision.

Precautions

General

Proparacaine should be used cautiously and sparingly in patients with known allergies, cardiac disease, or hyperthyroidism. The long-term toxicity of proparacaine is unknown; prolonged use may possibly delay wound healing. Although exceedingly rare with ophthalmic application of local anesthetics, it should be borne in mind that systemic toxicity (manifested by central nervous system stimulation followed by depression) may occur.

Protection of the eye from irritating chemicals, foreign bodies and rubbing during the period of anesthesia is very important. Tonometers soaked in sterilizing or detergent solutions should be thoroughly rinsed with sterile distilled water prior to use. Patients should be advised to avoid touching the eye until the anesthesia has worn off. Do not touch dropper tip to any surface as this may contaminate the solution.

Adverse Reactions

Pupillary dilatation or cycloplegic effects have rarely been observed with proparacaine hydrochloride. The drug appears to be safe for use in patients sensitive to other local anesthetics, but local or systemic sensitivity occasionally occurs. Instillation of proparacaine in the eye at recommended concentration and dosage usually produces little or no initial irritation, stinging, burning, conjunctival redness, lacrimation or increased winking. However, some local irritation and stinging may occur several hours after the instillation.

Rarely, a severe, immediate-type, apparently hyperallergic corneal reaction may occur which includes acute, intense and diffuse epithelial keratitis; a gray, ground-glass appearance; sloughing of large areas of necrotic epithelium; corneal filaments and, sometimes, iritis with descemetitis.

Allergic contact dermatitis with drying and fissuring of the fingertips has been reported.

Softening and erosion of the corneal epithelium and conjunctival congestion and hemorrhage have been reported.

Storage:

Refrigerate at 2° to 8°C (36° to 46°F). Keep bottle tightly closed. Store in carton until empty to protect from light. If solution shows more than a faint yellow color, it should not be used.

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