Polyflex for Cattle - 25 gm (200 ml) - [Respiratory Health]

Polyflex (ampicillin for injectable suspension) is an antibiotic for the treatment of infections caused by Gram-positive and Gram-negative bacteria, including bacterial pneumonia.

• Approved for use in dairy and beef cattle and calves.
• Polyflex is a ß-lactam class of antibiotics and requires a veterinary prescription.

Key Features

• Polyflex is a fast-acting treatment against respiratory tract infections.
• Provides bactericidal activity against Gram-positive and Gram-negative bacteria.
• Labeled for treatment of bacterial pneumonia (shipping fever, calf pneumonia and bovine pneumonia) caused Aerobacter spp., Klebsiella spp., Staphylococcus spp.,
• Streptococcus spp., Pasteurella multocida and E. coli susceptible to ampicillin trihydrate.
• Polyflex offers a more economical alternative to expensive third-generation cephalosporin drugs.

How It Works

Polyflex is an antibiotic injectable solution that offers bactericidal bacteria against susceptible gram-negative and gram-positive bacteria. Some of the many uses of Polyflex are:

• E.coli
• Pasteurella multocida
• Streptococcus spp.
• Staphylococcus spp.
• Klebsiella spp.
• Aerobacter spp.
• Bacterial pneumonia (bovine pneumonia, calf pneumonia, and shipping fever)
• Respiratory tract infections

Indications

Polyflex has proved effective in the treatment of many infections previously beyond the spectrum of penicillin therapy. This drug is particularly indicated in the treatment of the following infections caused by susceptible strains of organisms:

Dogs and Cats - Respiratory Tract Infections: Upper respiratory infections, tonsillitis and bronchopneumonia due to hemolytic streptococci, Staphylococcus aureus, Escherichia coli, Proteus mirabilis and Pasteurella spp.

Urinary Tract Infections due to Proteus mirabilis, Escherichia coli,Staphylococcus spp., hemolytic streptococci and Enterococcus spp.

Skin, Soft Tissue and Post-Surgical Infections: Abscesses, pustular dermatitis, cellulitis and infections of the anal gland, due to Escherichia coli, Proteus mirabilis,hemolytic streptococci, Staphylococcus spp. and Pasteurella spp.

Cattle and Calves Including Non-Ruminating (Veal Calves) - Respiratory Tract Infections: Bacterial pneumonia (shipping fever, calf pneumonia and bovine pneumonia) caused by Aerobacter spp., Klebsiella spp., Staphylococcus spp., Streptococcus spp., Pasteurella multocida and E. coli susceptible to ampicillin trihydrate.

Dosage: The dosage of Polyflex will vary according to the animal being treated, the severity of the infection and the animal's response.

Dogs and Cats - The recommended dose for dogs or cats is 3 mg/lb of body weight administered twice daily by subcutaneous or intramuscular injection.

Cattle and Calves Including Non-Ruminating (Veal Calves) - From 2 mg to 5 mg/lb of body weight once daily by intramuscular injection. Do not treat for more than 7 days.

In all species, 3 days treatment is usually adequate, but treatment should be continued for 48 to 72 hours after the animal has become afebrile or asymptomatic.

Mixing, Administration and Storage:

1. Transfer 79 ml of sterile water into the bottle of Polyflex.
2. Gently shake the bottle to rehydrate 100 mLs of Polyflex.
3. Administer intramuscular at 2 mL per 100 lbs. bodyweight.
4. After rehydration, store in a refrigerator for up to 3 months.

Top Reasons to Use Polyflex with Total Confidence

Polyflex goes beyond conventional penicillin therapy. POLYFLEX offers reliable treatment of infections, caused by Gram-positive and Gram-negative bacteria.

1. Fast-acting treatment against respiratory tract infections
• Labeled for treatment of bacterial pneumonia (shipping fever, calf pneumonia and bovine pneumonia) caused Aerobacter spp., Klebsiella spp., Staphylococcus spp.,
• Streptococcus spp., Pasteurella multocida and E. coli susceptible to ampicillin trihydrate.
2. Short milk and meat withdrawal times
• Follow the 48-hour milk withholding and six-day slaughter withdrawal times after the last treatment. POLYFLEX has predictable withdrawal periods when compared to more variable withdrawal periods associated with the use of penicillin.
3. Convenient Dosing at 2mL per 100 lbs*
• *Start by adding 79 mL sterile water to the bottle. Gently shake to reconstitute and make 100 mLs of POLYFLEX. Administer 2 mL per 100 lbs body weight. This delivers 5 mg ampicillin per lb body weight.
• For flexible dosing, consult your veterinarian for guidance when using the flexible dosing from 2 mg-5 mg/lb.
4. Economical treatment cost
• POLYFLEX offers a more economical treatment cost compared to third-generation cephalosporin drugs.

Mixing and Storage

• POLYFLEX is supplied as 25 grams of ampicillin sterile powder in a glass bottle.
• Follow label directions and use sterile water to rehydrate the sterile powder and to create POLYFLEX ampicillin injection for suspension.
• After rehydration, POLYFLEX can be stored under refrigeration for up to 3 months.

POLYFLEX Dosage and Safety

Dosage Information

• Approved for use in cattle (including lactating dairy cows) and calves (including non-ruminating veal calves). Always follow milk and meat withdrawal per the label.
• Cattle and calves: 2 to 5 mg/lb of body weight once daily by intramuscular (IM) injection. Do not treat with POLYFLEX for more than seven days.
• Three days' treatment is usually adequate, but treatment should be continued for 48 to 72 hours after the animal has become afebrile or asymptomatic.

Caution:

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Contraindications:

A history of allergic reactions to penicillin, cephalosporins or their analogues should be considered a contradication for the use of this agent.

Residue Warnings:

1. Do not treat cattle for more than 7 days.
2. Milk from treated cows must not be used for food during treatment, and for 48 hours (4 milkings) after the last treatment.
3. Cattle must not be slaughtered for food during treatment, and for 144 hours (6 days) after the last treatment.

Precautions:

Because it is a derivative of 6-aminopenicillanic acid, POLYFLEX has the potential for producing allergic reactions. If they should occur, POLYFLEX should be discontinued and the subject treated with the usual agents (antihistamines, pressor amines, corticosteroids).

Safety Information

Do not treat cattle for more than 7 days. Milk from treated cows must not be used for food during treatment, and for 48 hours (4 milkings) after the last treatment. Cattle must not be slaughtered for food during treatment, and for 144 hours (6 days) after the last treatment.

POLYFLEX has the potential for producing allergic reactions because it is a derivative of 6 aminopenicillanic acid. If a reaction should occur, discontinue use of POLYFLEX and treat the subject with the usual agents (antihistamines, pressor amines, corticosteroids).

Storage:

Store at or below 25°C (77°F) with excursions permitted up to 30°C (86°F). After reconstitution, store under refrigeration.