Ondansetron is an antiemetic drug used to treat or prevent severe vomiting in dogs and cats. While the FDA has approved it only for use in humans, veterinarians may prescribe it in certain situations.
Ondansetron is a drug that selectively inhibits serotonin 5HT3 receptors. 5HT3 receptors are located on vagal nerve terminals, enteric neurons in the GI tract, and centrally in the brain in a region called the chemoreceptor trigger zone.
Ondansetron is an antiemetic used for severe vomiting in dogs and cats. Ondansetron,metoclopramide, and maropitant are equally effective in reducing the frequency of vomiting in dogswith parvoviral enteritis. Ondansetron can be particularly effective for treating chemotherapy-associated vomiting. A study in cats found that ondansetron 0.22 mg/kg IM administered withdexmedetomidine and buprenorphine (in the same syringe) reduced the incidence (≈33%) and severityof nausea and vomiting when compared to ondansetron given 30 minutes before dexmedetomidine andbuprenorphine (67%) or when ondansetron was not given (76%).
Consult with your veterinarian on recommended dosage