Macrosyn for Cattle & Swine - Injectable Solution, 100-mg, 100-mL - [Respiratory Health]

Macrosyn Injectable Solution is an antibiotic indicated for the treatment of bovine respiratory disease (BRD), infectious bovine keratoconjunctivitis (pinkeye), and foot rot in beef and non-lactating dairy cattle and for treatment and control of swine respiratory disease (SRD) in swine.

Key Benefits:

• Broad-spectrum antibiotic to treat the major causes of BRD in cattle.
• Broad-spectrum antibiotic to treat the major causes of SRD in swine.
• Low-volume dose.
• Easy syringeability.
• Rapidly absorbs into the body tissues post administration.
• Made in North America.

Indications

Beef and Non-lactating Dairy Cattle

BRD - Macrosyn Injectable Solution is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis; and for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis.

IBK - Macrosyn Injectable Solution is indicated for the treatment of infectious bovine keratoconjunctivitis (IBK) associated with Moraxella bovis.

Foot Rot - Macrosyn Injectable Solution is indicated for the treatment of bovine foot rot (interdigital necrobacillosis) associated with Fusobacterium necrophorum and Porphyromonas levii.

Suckling Calves, Dairy Calves, and Veal Calves

BRD - Macrosyn Injectable Solution is indicated for the treatment of BRD associated with M. haemolytica, P. multocida, H. somni, and M. bovis.

Swine Macrosyn Injectable Solution is indicated for the treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica, Haemophilus parasuis, and Mycoplasma hyopneumoniae; and for the control of SRD associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, and Mycoplasma hyopneumoniae in groups of pigs where SRD has been diagnosed.

Cattle

Inject subcutaneously as a single dose in the neck at a dosage of 2.5 mg/kg (1.1 mL/100 lb) body weight (BW). Do not inject more than 10 mL per injection site.

Swine

Inject intramuscularly as a single dose in the neck at a dosage of 2.5 mg/kg (0.25 mL/22 lb) BW. Do not inject more than 2.5 mL per injection site.

Contraindications:

The use of Macrosyn Injectable Solution is contraindicated in animals previously found to be hypersensitive to the drug.

Precautions:

Cattle The effects of Macrosyn on bovine reproductive performance, pregnancy, and lactation have not been determined. Subcutaneous injection can cause a transient local tissue reaction that may result in trim loss of edible tissue at slaughter.

Swine The effects of Macrosyn on porcine reproductive performance, pregnancy, and lactation have not been determined. Intramuscular injection can cause a transient local tissue reaction that may result in trim loss of edible tissue at slaughter.

ADVERSE REACTIONS

Cattle In one BRD field study, two calves treated with tulathromycin injection at 2.5 mg/kg BW exhibited transient hypersalivation. One of these calves also exhibited transient dyspnea, which may have been related to pneumonia.

Swine In one field study, one out of 40 pigs treated with tulathromycin injection at 2.5 mg/kg BW exhibited mild salivation that resolved in less than four hours.

Storage Conditions:

Store at or below 25°C (77°F).

100 mL - Use within 28 days of first puncture and puncture a maximum of 17 times with a needle.

250 mL - Use within 28 days of first puncture and puncture a maximum of 29 times with a needle or 5 times with a dosage delivery device. If using a needle or draw-off spike larger than 4 gauge, discard any remaining product immediately after use.

500 mL - Use within 28 days of first puncture and puncture a maximum of 29 times with a needle or 5 times with a dosage delivery device. If using a needle or draw-off spike larger than 4 gauge, discard any remaining product immediately after use.