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Incurin Tablets 1 mg, 30 Ct.

Item# IWM044741
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Recurring Saings in EprxAUTOSHIP & SAVE[Details]
Recurring Saings in EprxAUTOSHIP & SAVE[Details]
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Incurin Tablets are an effective treatment for the control of estrogen-responsive urinary incontinence in dogs that have undergone surgical removal of the ovaries and uterus (ovariohysterectomy). This medication has been used effectively worldwide for more than 12 years. Incurin Tablets require a prescription from your veterinarian.

Key Benefits

  • Proven effective in reducing or eliminating urinary incontinence
  • Convenient, once-a-day dosing
  • One simple starting dose for all female dogs, regardless of weight or age
  • Can be titrated to the lowest effective dose

How It Works

Incurin Tablets contain the active ingredient estriol, a natural estrogen, which increases the resting muscle tone of the urethra in female dogs and can be used in the treatment of urinary incontinence due to estrogen depletion. It is given once a day with a starting dose of two tablets for any female dog, regardless of age or weight. The dose of Incurin Tablets is then titrated down over time to the lowest effective dose.


Incurin Tablets are indicated for the control of estrogen-responsive urinary incontinence inovariohysterectomized female dogs.

Incurin Tablets is a registered trademark of Intervet Inc., d/b/a Merck Animal Health, a subsidiary of Merck & Co. Inc.


Active Ingredients



View Incurin Drug Facts Sheet.

The dose of Incurin Tablets is not dependent upon body weight. All dogs should receive an initial dose of 2 mg Incurin Tablets (2 tablets) orally once per day for a minimum of 14 days. After urinary incontinence is controlled, the lowest effective daily dose of Incurin Tablets should be determined by decreasing the dose in a step-wise manner from 2 mg once daily (2 tablets) to 1 mg oncedaily (1 tablet), then 0.5 mg once daily (1/2 tablet) depending upon the response of the individual dog. There should be a minimum of 7 days between each dose adjustment. After the lowest daily dose that controls urinary incontinence is identified, the dose may be decreased further by administering once every two days. Dogs should not receive more than 2 mg Incurin Tablets per day (2 tablets). If thedog does not respond to 2 mg of Incurin Tablets per day, the diagnosis should be re-assessed.


Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Human Warnings

Not for human use. Keep out of the reach of children. Women who are of child-bearing age or those who are breast feeding should use caution when administering Incurin Tablets. Wash your hands with soap and water after administration to avoid exposure to the drug. Consult a physician in case of accidental ingestion by humans.

Animal Warnings

Some estrogens have been associated with bone marrow changes and an increased risk of mammary tumors. However, target animal safety study results and foreign post-market pharmacovigilance data for Incurin Tablets have shown that estriol-treated dogs are at low risk for developing these conditions.


Evaluation of factors contributing to urinary incontinence should be considered prior of administration of Incurin Tablets.

Do not use with other estrogens. The concomitant use of Incurin Tablets with other estrogens has not been evaluated.

The concomitant use of Incurin Tablets with glucocorticoids has not been evaluated.

The use of Incurin Tablets in dogs with liver disease has not been evaluated.

The safe use of Incurin Tablets has not been evaluated in intact female dogs, pregnant or lactating dogs, male dogs, and dogs less than 1 year of age.

Possible Side Effects

Please contact your veterinarian if your pet is suffering from gastrointestinal and estrogenic effects, or if the color or texture of your pet’s vulva changes.


Store at or below 25C (77°F) with excursions permitted to 40°C (104°F)


Incurin Tablets are used for the treatment and control of urinary incontinence that is estrogen-responsive for female dogs that have undergone ovariohysterectomy (surgical removal of the ovaries and uterus).
The dose of Incurin Tablets is not body weight-dependent; all dogs receive an initial dose of 2 tablets orally once per day for a minimum of 14 days. After control of urinary incontinence has been achieved, the lowest effective daily dose should be determined by decreasing the dose in a step-wise manner from 2 tablets, to 1 tablet, then a 1/2 tablet depending on your dog's response. There should be a minimum of 7 days between each dose adjustment. When the lowest dose that controls urinary incontinence is identified, the dose may be decreased further by administering once every two days.
The most common side effects associated with Incurin Tablets treatment under field conditions included loss of appetite, vomiting, excessive water drinking, and swollen vulva.
The safety and effectiveness of Incurin Tablets have not been evaluated in dogs less than 1 year of age, intact female dogs, male dogs, dogs used for breeding, or lactating dogs. Incurin Tablets are contraindicated in dogs showing polyuria (production of excessive amounts of urine) secondary to polydipsia (excessive thirst), or in pregnant dogs.
Contact your veterinarian immediately.


Review Summary
16 Reviews
81% (13)
13% (2)
6% (1)
0% (0)
0% (0)
100% Recommend this product (16 of 16 responses)
By Trisha
Abilene, TX
50 percent cost savings
January 26, 2024
Love this company! Same meds , 1/2 price
By Bernie
quick & convenient
December 28, 2023
This works out very well
By Stephanie K.
Incurin is helping
December 9, 2023
My Yorkie has become incontinent during a deep sleep due to a relaxed sphincter muscle. She is only 7 years old but this happens as a result of spaying if something goes wrong. Incurin has started working after only the first three days. She leaks very little now during the night. She’s only bee on it for 5 days. I suspect within a week or 10 days she’ll no longer leak urine. She has had no side effects from this medication.
By Jim
Anacortes, WA
Incurin Tablets
March 6, 2021
Incurin has been very helpful to our aging Rhodesian Ridgeback.
The price is very acceptable. Once sent, it arrives in a timely matter.
By jack
St Louis, MO
Good product
October 22, 2020
Cheaper than vet.
  • Wouldn't accept coupon code and emails are ignored about it.
By Charlie L.
Jacksonville FL
Fast, Efficient Service
August 22, 2020
I was very please with the fast and friendly service I received.
By Maia
Excellent price!
July 5, 2020
Although it took awhile for the vet to approve the order, I was very pleased with the product because of the price. It's also great to get items directly to our house.
By Cynthia K.
GA - Georgia
It works!
April 12, 2020
After using another product for a couple of years, it sometimes worked and the side effects of agitation & unease, made for a nervous female dog. The incurin works so far. 2 months. Our dog actually relaxes and takes naps during the day. No leaks and the dosage keeps going down as she stays on it longer. As prescribed. Small pill easy to give.
By Kathy
memphis, tn
5 star rating
December 15, 2019
Female dog having Good Results
By Dogdad
Cleveland, OH
March 7, 2019
Great price and fast delivery!
Easy ordering and prescription verification.
By Teri
Tampa, FL
Prescription done quickly
February 15, 2019
I placed my order and within 2 days it was approved and received it in a few days. Great service. I will continue to use them in the future
By Sydney
Incurin effective for dog incontinence
December 6, 2018
Incurin has been an effective product for my 13-1/2 year old Terrier. This prescription was prescribed by our veterinarian. It took approximately three weeks to work completely without urinary leakage accidents. The urinary incontience was primarily due to my dog's age and being able to fully empty her bladder due to hip arthritis/dysplasia. I am very pleased that Incurin is available through Entirely Pets Pharmacy where I pay considerably less than what the veterinarian charges for this medication. Thank you Entirely Pets!
  • Controls urinary leakage due to age and other health issues.
  • Dog no longer has accidents and can hold her urine.
  • If you experience urinary leakage with your dog, it is a life-changer
  • This is not really a negative. In our case, the medication efficacy was gradual and by three weeks, no more accidents and urinary leaks. My experience... give this medication time to work.
By Dale
Great Service
August 24, 2018
Easy to reorder and fast shipping, Thank You
By Steve
Cuyahoga Falls, OH
Easy, peezie, lemon squeezy!
January 3, 2016
Simple and fast (and accurate!).
By Linda S.
Pleasant Prairie, WI
Works well for my dog
August 26, 2015
My BullMastif had incontinence problems after spay surgery. She has used Incurin for about a year now and has not leaked at all. She has regular blood work done to make sure all is well taking the product. Works well for her.
By roger n.
Saint Louis
My vet originally prescribed Proin. For most dogs that's okay but for some it could lead to death
June 6, 2015
We found incurin! After a year or so on it, given it every other day I've had mixed results. She could go months without Leaking where she sleeps as long as the dose is maintained. I think it was when we moved her to every three days we started having problems. She's a Doberman so she has psychotic problems inherent in the breed. Is her wetting(leaking) the bed half psychological? I don't know
It's weird because she does not need to go to the bathroom early in the morning she holds it until about 11 o'clock. (It's almost as though she doesn't want to be bothered with Going to the bathroom)

Overall I would say that Incurin is an excellent product. I would recommend this product before you go to Proin

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